JPS5533435A - 2-phenyl-1-phthalazone derivative - Google Patents

2-phenyl-1-phthalazone derivative

Info

Publication number
JPS5533435A
JPS5533435A JP10629678A JP10629678A JPS5533435A JP S5533435 A JPS5533435 A JP S5533435A JP 10629678 A JP10629678 A JP 10629678A JP 10629678 A JP10629678 A JP 10629678A JP S5533435 A JPS5533435 A JP S5533435A
Authority
JP
Japan
Prior art keywords
phenyl
formula
phthalazone
compound
formyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP10629678A
Other languages
Japanese (ja)
Inventor
Masayuki Ishikawa
Masao Eguchi
Hiromichi Tanaka
Shigeru Ito
Yoshimi Takashima
Masahiko Kobayashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to JP10629678A priority Critical patent/JPS5533435A/en
Publication of JPS5533435A publication Critical patent/JPS5533435A/en
Pending legal-status Critical Current

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:2-Phenyl-1-phthalazone derivatives of formula I (R1WR5 are alkyls; R4 and R5 may incorporate to form disubstituted methylene group; R6 and R7 are alkyl).
EXAMPLE: The compound of formula III.
USE: Since said derivatives have antithromboxane activity, they are useful as preventive and remedy for artoriosclerotic, thrombosis, isthemic cardiopathy and cerebrovascular diseases.
PREPARATION: The reaction between 1 mole of 4-formyl-2-phenyl-1-phthalazone of formula IV as 7-ethoxycarbonyl-6, 8-dimethyl-4-formyl-2-phenyl-1-phthalazone and more than 1 mole, preferably 2W3 moles, of a compound of formula V is effected preferably in a solvent of benzene and in the presence of a catalyst of pyridine or the like to produce the compound of formula I.
COPYRIGHT: (C)1980,JPO&Japio
JP10629678A 1978-09-01 1978-09-01 2-phenyl-1-phthalazone derivative Pending JPS5533435A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP10629678A JPS5533435A (en) 1978-09-01 1978-09-01 2-phenyl-1-phthalazone derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP10629678A JPS5533435A (en) 1978-09-01 1978-09-01 2-phenyl-1-phthalazone derivative

Publications (1)

Publication Number Publication Date
JPS5533435A true JPS5533435A (en) 1980-03-08

Family

ID=14430067

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10629678A Pending JPS5533435A (en) 1978-09-01 1978-09-01 2-phenyl-1-phthalazone derivative

Country Status (1)

Country Link
JP (1) JPS5533435A (en)

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