JPS5540604A - Improved local topicum - Google Patents

Improved local topicum

Info

Publication number
JPS5540604A
JPS5540604A JP11227278A JP11227278A JPS5540604A JP S5540604 A JPS5540604 A JP S5540604A JP 11227278 A JP11227278 A JP 11227278A JP 11227278 A JP11227278 A JP 11227278A JP S5540604 A JPS5540604 A JP S5540604A
Authority
JP
Japan
Prior art keywords
topicum
polymeric compound
hpc
active component
water
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP11227278A
Other languages
Japanese (ja)
Other versions
JPS6218526B2 (en
Inventor
Masuji Yoshii
Toshihiko Imazato
Toshiro Asahina
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsui Toatsu Chemicals Inc
Original Assignee
Mitsui Toatsu Chemicals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsui Toatsu Chemicals Inc filed Critical Mitsui Toatsu Chemicals Inc
Priority to JP11227278A priority Critical patent/JPS5540604A/en
Publication of JPS5540604A publication Critical patent/JPS5540604A/en
Publication of JPS6218526B2 publication Critical patent/JPS6218526B2/ja
Granted legal-status Critical Current

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  • Medicinal Preparation (AREA)

Abstract

PURPOSE: To prepare a local topicum gel suppressing bleeding of the polymeric compound on the surface of the skin, thereby giving improved feeling in use, and containing a specific cellulosic polymeric compound.
CONSTITUTION: A topicum containing a cellulosic polymeric compound soluble in water and alcohols, preferably hydroxypropylcellulose (HPC). HPC is registered in the Japan PHarmacopoeia and prepared by reacting cellulose with propylene oxide. A topicum containing about 1W5wt% of HPC can suppress the bleeding. The specific cellulosic polymeric compound is particularly useful for topicums comprising a carboxyvinyl polymer as a base. In compounding the gel for an aqueous topicum with an active component poorly soluble in water, addition of propylene carbonate is effective to improve the solubility of the active component.
COPYRIGHT: (C)1980,JPO&Japio
JP11227278A 1978-09-14 1978-09-14 Improved local topicum Granted JPS5540604A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP11227278A JPS5540604A (en) 1978-09-14 1978-09-14 Improved local topicum

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP11227278A JPS5540604A (en) 1978-09-14 1978-09-14 Improved local topicum

Publications (2)

Publication Number Publication Date
JPS5540604A true JPS5540604A (en) 1980-03-22
JPS6218526B2 JPS6218526B2 (en) 1987-04-23

Family

ID=14582543

Family Applications (1)

Application Number Title Priority Date Filing Date
JP11227278A Granted JPS5540604A (en) 1978-09-14 1978-09-14 Improved local topicum

Country Status (1)

Country Link
JP (1) JPS5540604A (en)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5750914A (en) * 1980-09-12 1982-03-25 Shionogi & Co Ltd Betamethasone external pharmaceutical
EP0101178A2 (en) 1982-07-13 1984-02-22 Pfizer Corporation Topical anti-inflammatory compositions
JPS6168413A (en) * 1984-09-10 1986-04-08 Lion Corp External gel composition
JPS61257920A (en) * 1985-05-13 1986-11-15 Sato Seiyaku Kk Antimycotic gelatinous agent for external use
JPS6251619A (en) * 1985-08-30 1987-03-06 Wako Pure Chem Ind Ltd Gel pharmaceutical for external use
JPS6251617A (en) * 1985-08-30 1987-03-06 Wako Pure Chem Ind Ltd Vidarabin gel ointment
US4664909A (en) * 1980-12-29 1987-05-12 Colgate-Palmolive Company Stable suspension of powder in alcoholic media
WO1989010745A1 (en) * 1988-05-02 1989-11-16 Pomerantz, Edwin Compositions and in situ methods for forming films on body tissue
US5840809A (en) * 1995-07-03 1998-11-24 Daicel Chemical Industries, Ltd. Epoxidized block copolymer, its production, and its composition
JP2010241824A (en) * 2003-04-28 2010-10-28 Bayer Schering Pharma Ag Pharmaceutical composition in the form of hydrogel for transdermal administration of active substance

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5750914A (en) * 1980-09-12 1982-03-25 Shionogi & Co Ltd Betamethasone external pharmaceutical
US4664909A (en) * 1980-12-29 1987-05-12 Colgate-Palmolive Company Stable suspension of powder in alcoholic media
EP0101178A2 (en) 1982-07-13 1984-02-22 Pfizer Corporation Topical anti-inflammatory compositions
JPS6168413A (en) * 1984-09-10 1986-04-08 Lion Corp External gel composition
JPS61257920A (en) * 1985-05-13 1986-11-15 Sato Seiyaku Kk Antimycotic gelatinous agent for external use
JPS6251619A (en) * 1985-08-30 1987-03-06 Wako Pure Chem Ind Ltd Gel pharmaceutical for external use
JPS6251617A (en) * 1985-08-30 1987-03-06 Wako Pure Chem Ind Ltd Vidarabin gel ointment
WO1989010745A1 (en) * 1988-05-02 1989-11-16 Pomerantz, Edwin Compositions and in situ methods for forming films on body tissue
US5840809A (en) * 1995-07-03 1998-11-24 Daicel Chemical Industries, Ltd. Epoxidized block copolymer, its production, and its composition
JP2010241824A (en) * 2003-04-28 2010-10-28 Bayer Schering Pharma Ag Pharmaceutical composition in the form of hydrogel for transdermal administration of active substance
JP4829102B2 (en) * 2003-04-28 2011-12-07 バイエル ファーマ アクチエンゲゼルシャフト Pharmaceutical composition in the form of a hydrogel for transdermal administration of the active ingredient

Also Published As

Publication number Publication date
JPS6218526B2 (en) 1987-04-23

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