JPS5540656A - Substituted quinoline-carboxylic acid derivative - Google Patents

Substituted quinoline-carboxylic acid derivative

Info

Publication number
JPS5540656A
JPS5540656A JP11495178A JP11495178A JPS5540656A JP S5540656 A JPS5540656 A JP S5540656A JP 11495178 A JP11495178 A JP 11495178A JP 11495178 A JP11495178 A JP 11495178A JP S5540656 A JPS5540656 A JP S5540656A
Authority
JP
Japan
Prior art keywords
compound
formula
substituted
carboxylic acid
acid derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP11495178A
Other languages
Japanese (ja)
Other versions
JPS6257623B2 (en
Inventor
Tsutomu Irikura
Seigo Suzue
Hiroshi Koga
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kyorin Pharmaceutical Co Ltd
Original Assignee
Kyorin Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyorin Pharmaceutical Co Ltd filed Critical Kyorin Pharmaceutical Co Ltd
Priority to JP11495178A priority Critical patent/JPS5540656A/en
Publication of JPS5540656A publication Critical patent/JPS5540656A/en
Publication of JPS6257623B2 publication Critical patent/JPS6257623B2/ja
Granted legal-status Critical Current

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  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:A compound (or ester) of formula I: [R is (substituted) lower alkyl, alkenyl, alkynyl group, etc.; X and Y are H or halogen and not H at the same time; n is 0, 1, or 2; A is (substituted) amino, OH, or (substituted) cyclic amino group], and its salt.
EXAMPLE: 1-Ethyl-1,4-dihydro-7-( 4-dimethylamino-1-piperidinyl )-6-fluoro-4-oxoquinoline-3-carboxylic acid.
USE: Useful as antibacterials having a great antibacterial activity against Gram-positive and Gram-negative bacteria.
PROCESS: A compound of formula II: (Z is halogen) is reacted with a compound of formula III in the presence of a solvent at room temperature of 200°C to give the objective compound of formula I.
COPYRIGHT: (C)1980,JPO&Japio
JP11495178A 1978-09-19 1978-09-19 Substituted quinoline-carboxylic acid derivative Granted JPS5540656A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP11495178A JPS5540656A (en) 1978-09-19 1978-09-19 Substituted quinoline-carboxylic acid derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP11495178A JPS5540656A (en) 1978-09-19 1978-09-19 Substituted quinoline-carboxylic acid derivative

Publications (2)

Publication Number Publication Date
JPS5540656A true JPS5540656A (en) 1980-03-22
JPS6257623B2 JPS6257623B2 (en) 1987-12-02

Family

ID=14650683

Family Applications (1)

Application Number Title Priority Date Filing Date
JP11495178A Granted JPS5540656A (en) 1978-09-19 1978-09-19 Substituted quinoline-carboxylic acid derivative

Country Status (1)

Country Link
JP (1) JPS5540656A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3135125A1 (en) * 1980-09-05 1982-06-03 Kyorin Seiyaku K.K., Tokyo Process for preparing 6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid compounds
US4617308A (en) * 1985-01-25 1986-10-14 Warner-Lambert Company 7-substituted amino-1-aryl-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids and derivatives thereof as antibacterial agents
US4666920A (en) * 1984-03-17 1987-05-19 Bayer Aktiengesellschaft Antibacterial 1,7-diamino-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3135125A1 (en) * 1980-09-05 1982-06-03 Kyorin Seiyaku K.K., Tokyo Process for preparing 6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid compounds
US4666920A (en) * 1984-03-17 1987-05-19 Bayer Aktiengesellschaft Antibacterial 1,7-diamino-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids
US4753925A (en) * 1984-03-17 1988-06-28 Bayer Aktiengesellschaft Antibacterial 1,7-diamino-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids
US4617308A (en) * 1985-01-25 1986-10-14 Warner-Lambert Company 7-substituted amino-1-aryl-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids and derivatives thereof as antibacterial agents

Also Published As

Publication number Publication date
JPS6257623B2 (en) 1987-12-02

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