JPS5583781A - Pyridazinone derivative - Google Patents

Pyridazinone derivative

Info

Publication number
JPS5583781A
JPS5583781A JP15807978A JP15807978A JPS5583781A JP S5583781 A JPS5583781 A JP S5583781A JP 15807978 A JP15807978 A JP 15807978A JP 15807978 A JP15807978 A JP 15807978A JP S5583781 A JPS5583781 A JP S5583781A
Authority
JP
Japan
Prior art keywords
compound
formula
reacted
give
lower alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP15807978A
Other languages
Japanese (ja)
Other versions
JPS6257628B2 (en
Inventor
Noburo Setoguchi
Tatsu Nakao
Hiroshi Mikashima
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tanabe Pharma Corp
Original Assignee
Yoshitomi Pharmaceutical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yoshitomi Pharmaceutical Industries Ltd filed Critical Yoshitomi Pharmaceutical Industries Ltd
Priority to JP15807978A priority Critical patent/JPS5583781A/en
Publication of JPS5583781A publication Critical patent/JPS5583781A/en
Publication of JPS6257628B2 publication Critical patent/JPS6257628B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:A pyridazinone derivative of formula I: (R1 and R2 are lower alkyl groups, or may form a heterocyclic ring together with the adjacent N atom; R3 and R4 are H or lower alkyl groups; n is 2 or 3).
EXAMPLE: 1-( 2-Diethylaminoethyl )-4,4-dimethyl-6-(5-methyl-3-oxo-2,3,4,5-tetrahydropyridazin-6-yl)-1,2,3,4-tetrahydroquinolin-2-one hydrochloride-hemihydrate.
USE: Antithrombotics, antidepressive agents, and intermediates for their synthesis.
PROCESS: A compound of formula III is reacted with a compound of formula IV: (X is halogen) to give a compound of formula V, which is hydrolyzed to form a compound of formula II. The resulting compound or its reactive derivative is then reacted with hydrazine or its hydrate to give the compound of formula I.
COPYRIGHT: (C)1980,JPO&Japio
JP15807978A 1978-12-19 1978-12-19 Pyridazinone derivative Granted JPS5583781A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP15807978A JPS5583781A (en) 1978-12-19 1978-12-19 Pyridazinone derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP15807978A JPS5583781A (en) 1978-12-19 1978-12-19 Pyridazinone derivative

Publications (2)

Publication Number Publication Date
JPS5583781A true JPS5583781A (en) 1980-06-24
JPS6257628B2 JPS6257628B2 (en) 1987-12-02

Family

ID=15663828

Family Applications (1)

Application Number Title Priority Date Filing Date
JP15807978A Granted JPS5583781A (en) 1978-12-19 1978-12-19 Pyridazinone derivative

Country Status (1)

Country Link
JP (1) JPS5583781A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4415572A (en) * 1980-10-31 1983-11-15 Otsuka Pharmaceutical Co., Ltd. Piperazinylcarbostyril compounds
US5656633A (en) * 1991-05-08 1997-08-12 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivatives and pharmaceutical compositions containing the same for use as a disturbance-of-consciousness improving agent, central nervous system stimulant or sigma receptor agonist

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4415572A (en) * 1980-10-31 1983-11-15 Otsuka Pharmaceutical Co., Ltd. Piperazinylcarbostyril compounds
US5656633A (en) * 1991-05-08 1997-08-12 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivatives and pharmaceutical compositions containing the same for use as a disturbance-of-consciousness improving agent, central nervous system stimulant or sigma receptor agonist

Also Published As

Publication number Publication date
JPS6257628B2 (en) 1987-12-02

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