JPS56135499A - Manufacture of steroidal delta4,6 dienone - Google Patents

Manufacture of steroidal delta4,6 dienone

Info

Publication number
JPS56135499A
JPS56135499A JP2365581A JP2365581A JPS56135499A JP S56135499 A JPS56135499 A JP S56135499A JP 2365581 A JP2365581 A JP 2365581A JP 2365581 A JP2365581 A JP 2365581A JP S56135499 A JPS56135499 A JP S56135499A
Authority
JP
Japan
Prior art keywords
delta4
dienone
steroidal
manufacture
steroidal delta4
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2365581A
Other languages
English (en)
Japanese (ja)
Inventor
Richiyaado Beeringu Jieemusu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GD Searle LLC
Original Assignee
GD Searle LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GD Searle LLC filed Critical GD Searle LLC
Publication of JPS56135499A publication Critical patent/JPS56135499A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/001—Lactones
    • C07J21/003—Lactones at position 17
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C07J7/004—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa
    • C07J7/0045—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa not substituted in position 16
    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
    • C25B3/00—Electrolytic production of organic compounds
    • C25B3/01—Products
    • C25B3/05—Heterocyclic compounds
    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
    • C25B3/00—Electrolytic production of organic compounds
    • C25B3/01—Products
    • C25B3/07—Oxygen containing compounds
    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
    • C25B3/00—Electrolytic production of organic compounds
    • C25B3/20—Processes
    • C25B3/23—Oxidation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Materials Engineering (AREA)
  • Metallurgy (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Electrolytic Production Of Non-Metals, Compounds, Apparatuses Therefor (AREA)
JP2365581A 1980-02-20 1981-02-19 Manufacture of steroidal delta4,6 dienone Pending JPS56135499A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/122,938 US4270994A (en) 1980-02-20 1980-02-20 Electrochemical dehydrogenation of steroidal Δ3,5 enol ethers under basic conditions to provide steroidal Δ4,6 dienones

Publications (1)

Publication Number Publication Date
JPS56135499A true JPS56135499A (en) 1981-10-22

Family

ID=22405765

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2365581A Pending JPS56135499A (en) 1980-02-20 1981-02-19 Manufacture of steroidal delta4,6 dienone

Country Status (7)

Country Link
US (1) US4270994A (2)
JP (1) JPS56135499A (2)
AU (1) AU6745681A (2)
CA (1) CA1181717A (2)
DE (1) DE3106162A1 (2)
FR (1) FR2476094A1 (2)
GB (1) GB2070017B (2)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5531908A (en) * 1993-08-20 1996-07-02 Suntory Limited Germ-free liquid dispenser
US5981744A (en) 1995-12-11 1999-11-09 G. D. Searle And Co. Processes for preparation of 9,11-epoxy steroids and intermediates useful therein
PT944644E (pt) 1996-12-11 2003-02-28 Searle & Co Processos para a preparacao de esteroides 9,11-epoxi e intermediarios uteis para esse efeito
US6887991B1 (en) * 1996-12-11 2005-05-03 G. D. Searle & Company Processes for preparation of 9, 11-epoxy steroids and intermediates useful therein
AU2003220251A1 (en) * 2002-03-22 2003-10-13 Pharmacia Corporation C-17 spirolactonization and 6,7 oxidation of steroids
US7235655B2 (en) * 2002-03-22 2007-06-26 Pharmacia & Upjohn Company Processes to prepare eplerenone
CL2004000574A1 (es) * 2003-03-21 2005-02-11 Pharmacia Corp Sa Organizada B Proceso para preparar un compuesto 17-espirolactona o la sal de lactona abierta por carbonilacion del correspondiente 17-alquenil o alquinil derivado, los intermediarios que se usan y su proceso de obtencion.
EP3922759A1 (en) * 2020-06-11 2021-12-15 Minakem Process of alpha,beta-desaturation of compounds containing a carbonyl moiety
CN114622228B (zh) * 2022-02-22 2024-04-26 浙江工业大学 一种电催化氧化制取甾体激素类羰基中间体的方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE621197A (2) * 1961-08-08
US3485829A (en) * 1967-04-10 1969-12-23 Syntex Corp Cyclobutano- and cyclobuteno-(3',4':6,7) derivatives of the androstane and 19-nor-androstane series
US3491090A (en) * 1967-04-10 1970-01-20 Syntex Corp Cyclobutano- and cyclobuteno - (3',4':6,7) derivatives of the corticoid series
GB1360904A (en) * 1972-01-19 1974-07-24 Ici Ltd Oxidation of aromatic compounds
DD125838A1 (2) * 1974-06-28 1977-05-25
DD134769A1 (de) * 1978-01-20 1979-03-21 Helmut Kasch Verfahren zur herstellung von 3-oxo-oestra-4,9,11-trienen

Also Published As

Publication number Publication date
AU6745681A (en) 1981-08-27
US4270994A (en) 1981-06-02
FR2476094A1 (fr) 1981-08-21
FR2476094B1 (2) 1983-07-29
CA1181717A (en) 1985-01-29
GB2070017A (en) 1981-09-03
DE3106162A1 (de) 1981-12-17
GB2070017B (en) 1984-11-07

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