JPS5626856A - Tetrapeptide - Google Patents

Tetrapeptide

Info

Publication number
JPS5626856A
JPS5626856A JP10238179A JP10238179A JPS5626856A JP S5626856 A JPS5626856 A JP S5626856A JP 10238179 A JP10238179 A JP 10238179A JP 10238179 A JP10238179 A JP 10238179A JP S5626856 A JPS5626856 A JP S5626856A
Authority
JP
Japan
Prior art keywords
formula
protecting group
tetrapeptide
glycyl
dipeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP10238179A
Other languages
Japanese (ja)
Other versions
JPS6055080B2 (en
Inventor
Tadahiro Doi
Tadashi Akita
Yoshiaki Kiso
Shizuo Nakamura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Pharmaceutical Co Ltd
Otsuka Pharmaceutical Factory Inc
Original Assignee
Otsuka Pharmaceutical Co Ltd
Otsuka Pharmaceutical Factory Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharmaceutical Co Ltd, Otsuka Pharmaceutical Factory Inc filed Critical Otsuka Pharmaceutical Co Ltd
Priority to JP54102381A priority Critical patent/JPS6055080B2/en
Publication of JPS5626856A publication Critical patent/JPS5626856A/en
Publication of JPS6055080B2 publication Critical patent/JPS6055080B2/en
Expired legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

NEW MATERIAL:The titled compound of formula I (X is Gly, Ala, Ser, etc.).
EXAMPLE: L-Tyrosyl-glycyl-glycyl-L-phenylalaninol.
USE: Useful as an analgesic, a narcotic antagonistic and an antidiarrheic drugs having an agonistic activity in the opiate acceptor and a prolonged duration with low toxicity, and including any of optical isomers and racemates.
PROCESS: A dipeptide of formula II (R3 is amino-protecting group; R4 is carboxyl- protecting group) is reacted with a dipeptide of formula III by the conventional peptide linkage forming method, e.g. the azide method, to give a tetrapeptide of formula IV, whose protecting group is eliminated by the conventional deprotection means to afford the tetrapeptide of formula I readily.
COPYRIGHT: (C)1981,JPO&Japio
JP54102381A 1979-08-10 1979-08-10 tetrapeptide Expired JPS6055080B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP54102381A JPS6055080B2 (en) 1979-08-10 1979-08-10 tetrapeptide

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP54102381A JPS6055080B2 (en) 1979-08-10 1979-08-10 tetrapeptide

Publications (2)

Publication Number Publication Date
JPS5626856A true JPS5626856A (en) 1981-03-16
JPS6055080B2 JPS6055080B2 (en) 1985-12-03

Family

ID=14325867

Family Applications (1)

Application Number Title Priority Date Filing Date
JP54102381A Expired JPS6055080B2 (en) 1979-08-10 1979-08-10 tetrapeptide

Country Status (1)

Country Link
JP (1) JPS6055080B2 (en)

Also Published As

Publication number Publication date
JPS6055080B2 (en) 1985-12-03

Similar Documents

Publication Publication Date Title
JPS54148722A (en) Nonapeptide and its preparation
JPS5754157A (en) L-argininal derivative and its preparation
HUT49628A (en) Process for producing new peptides and pharmaceutical compositions comprising same
EP1108427A3 (en) Compositions for and uses thereof for altering gene expression with phenylacetate and derivatives thereof
DE122008000006I2 (en) Cyclic peptides with antifungal activity and VAnidulafungin and its pharmaceutically acceptable methods for their preparation. Salts.
KR880011198A (en) Cyclic Peptides and Methods for Making the Same
DE3061127D1 (en) Peptides having ubiquitin-like activity, process for their preparation, therapeutic compositions containing them and their use
JPS5455542A (en) Peptides, their acid salts, and their preparation
US4251439A (en) Pharmacologically active peptides
DE3162053D1 (en) N-acyl peptide compounds, processes for the preparation thereof and pharmaceutical compositions containing them
IE781291L (en) Psychopharmacological peptides
JPS5615256A (en) Novel tetrapeptide derivative
US4579841A (en) Dipeptide derivatives having opiate activity
JPS55164672A (en) Azetidine derivative and its preparation
JPS5626855A (en) Enkephalin derivative and its preparation
JPS56158753A (en) Kyotorphin derivative
JPS56108750A (en) Polypeptide and its preparation
JPS5645449A (en) Novel peptide, its pharmaceutically acceptable salt and preparation of the same
JPS5738756A (en) Tripeptide alkylamide derivative
JPS5785349A (en) Tripeptide alkylamide derivative
JPS5540601A (en) New 3-(3,4-dihydroxyphenyl)serine derivative
JPS55164671A (en) Azetidine derivative and its preparation
JPS55143993A (en) Azetidinone derivative and its preparation
JPS5735570A (en) Alpha-amino-beta-hydroxybutyryl-l-hystidine and its preparation
JPS56138180A (en) Di-n6',o3-demethylistamycin a and its preparation