JPS5629567A - Alpha-cycloalkylthio-phenylacetic acid - Google Patents
Alpha-cycloalkylthio-phenylacetic acidInfo
- Publication number
- JPS5629567A JPS5629567A JP10477079A JP10477079A JPS5629567A JP S5629567 A JPS5629567 A JP S5629567A JP 10477079 A JP10477079 A JP 10477079A JP 10477079 A JP10477079 A JP 10477079A JP S5629567 A JPS5629567 A JP S5629567A
- Authority
- JP
- Japan
- Prior art keywords
- cycloalkyl
- alkali metal
- cycloalkylthio
- alpha
- phenylacetic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 229960003424 phenylacetic acid Drugs 0.000 title 1
- 239000003279 phenylacetic acid Substances 0.000 title 1
- -1 α-Cyclohexylthiophenylacetic acid Chemical compound 0.000 abstract 7
- 229910052783 alkali metal Inorganic materials 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- WAKFRZBXTKUFIW-UHFFFAOYSA-N 2-bromo-2-phenylacetic acid Chemical compound OC(=O)C(Br)C1=CC=CC=C1 WAKFRZBXTKUFIW-UHFFFAOYSA-N 0.000 abstract 1
- 229930186147 Cephalosporin Natural products 0.000 abstract 1
- 229930182555 Penicillin Natural products 0.000 abstract 1
- JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 abstract 1
- 150000008044 alkali metal hydroxides Chemical class 0.000 abstract 1
- 239000012736 aqueous medium Substances 0.000 abstract 1
- 229940124587 cephalosporin Drugs 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 229940049954 penicillin Drugs 0.000 abstract 1
- 239000002243 precursor Substances 0.000 abstract 1
- 239000002994 raw material Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
NEW MATERIAL:A compound of formula (R is cycloalkyl) and its salt.
EXAMPLE: α-Cyclohexylthiophenylacetic acid.
USE: A precursor of penicillin and cephalosporin compounds.
PROCESS: The compound of formula is prepared by reacting α-bromophenylacetic acid with cycloalkyl mercaptan or its alkali metal salt in an aqueous medium at room temperature or below. When cycloalkyl mercaptan is used as a raw material, the reaction is carried out in the presence of an alkali metal hydroxide sufficient to form the alkali metal salt of the cycloalkyl mercaptan.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10477079A JPS5629567A (en) | 1979-08-16 | 1979-08-16 | Alpha-cycloalkylthio-phenylacetic acid |
| US06/137,292 US4297486A (en) | 1979-04-04 | 1980-04-03 | Aminoglycoside antibiotic G-367-1 and method for the production thereof |
| FR8007574A FR2452932A1 (en) | 1979-04-04 | 1980-04-03 | NOVEL AMINOGLYCOSIDE ANTIBIOTICS AND THEIR PRODUCTION |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10477079A JPS5629567A (en) | 1979-08-16 | 1979-08-16 | Alpha-cycloalkylthio-phenylacetic acid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS5629567A true JPS5629567A (en) | 1981-03-24 |
Family
ID=14389703
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP10477079A Pending JPS5629567A (en) | 1979-04-04 | 1979-08-16 | Alpha-cycloalkylthio-phenylacetic acid |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5629567A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5547573A (en) * | 1993-10-13 | 1996-08-20 | Robatel | Device for removing cake or residual layer in a centrifuge |
-
1979
- 1979-08-16 JP JP10477079A patent/JPS5629567A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5547573A (en) * | 1993-10-13 | 1996-08-20 | Robatel | Device for removing cake or residual layer in a centrifuge |
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