JPS5632485A - Preparation of organogermanium compound - Google Patents

Preparation of organogermanium compound

Info

Publication number
JPS5632485A
JPS5632485A JP10789679A JP10789679A JPS5632485A JP S5632485 A JPS5632485 A JP S5632485A JP 10789679 A JP10789679 A JP 10789679A JP 10789679 A JP10789679 A JP 10789679A JP S5632485 A JPS5632485 A JP S5632485A
Authority
JP
Japan
Prior art keywords
germanium
tetrahalogenide
trihalogenosilane
reacted
reacting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP10789679A
Other languages
Japanese (ja)
Other versions
JPS6228797B2 (en
Inventor
Shuzo Nagashima
Toshimitsu Suzuki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asai Germanium Research Institute
Pola Orbis Holdings Inc
Original Assignee
Asai Germanium Research Institute
Pola Chemical Industries Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asai Germanium Research Institute, Pola Chemical Industries Inc filed Critical Asai Germanium Research Institute
Priority to JP10789679A priority Critical patent/JPS5632485A/en
Publication of JPS5632485A publication Critical patent/JPS5632485A/en
Publication of JPS6228797B2 publication Critical patent/JPS6228797B2/ja
Granted legal-status Critical Current

Links

Abstract

PURPOSE: To obtain the titled compound useful for improving the features of diseases, e.g. various intractable diseases, by reacting a germanium tetrahalogenide with a trihalogenosilane in the presence of an organic base, reacting the resultant product with acrylic acid etc., and hydrolyzing the reaction product.
CONSTITUTION: A germanium tetrahalogenide, e.g. germanium tetrachloride, is reacted with a trihalogenosilane, e.g. trichlorosilane, with or without an inert solvent, e.g. benzene, under cooling in an ice bath, in the presence of an organic base, e.g. triethylamine or pyridine. The reaction mixture is then distilled to give the organic salt of a trihalogenogermane as a residue, which is then reacted with acrylic acid or acrylamide in the proesence of an anhydrous solvent, e.g. dioxane, at room temperature, and then hydrolyzed to give the compound of the formula.
USE: Beautifying effects on the skin and anti-inflammatory effects in addition to the treatment of intractable diseases, e.g. concer of the internal organ.
COPYRIGHT: (C)1981,JPO&Japio
JP10789679A 1979-08-24 1979-08-24 Preparation of organogermanium compound Granted JPS5632485A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP10789679A JPS5632485A (en) 1979-08-24 1979-08-24 Preparation of organogermanium compound

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP10789679A JPS5632485A (en) 1979-08-24 1979-08-24 Preparation of organogermanium compound

Publications (2)

Publication Number Publication Date
JPS5632485A true JPS5632485A (en) 1981-04-01
JPS6228797B2 JPS6228797B2 (en) 1987-06-23

Family

ID=14470809

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10789679A Granted JPS5632485A (en) 1979-08-24 1979-08-24 Preparation of organogermanium compound

Country Status (1)

Country Link
JP (1) JPS5632485A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4720564A (en) * 1984-04-25 1988-01-19 Asai Germanium Research Institute Antioxidant organogermanium compound
US5352815A (en) * 1992-03-16 1994-10-04 Asai Germanium Research Institute Co., Ltd. Agent for suppression and interception of mailard reaction
GB2279650A (en) * 1992-12-28 1995-01-11 Agency Ind Science Techn Process for isomerization of compound of aldose structure into compound of ketose structure,and isomerization agent or accelerator used therein

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4720564A (en) * 1984-04-25 1988-01-19 Asai Germanium Research Institute Antioxidant organogermanium compound
US5352815A (en) * 1992-03-16 1994-10-04 Asai Germanium Research Institute Co., Ltd. Agent for suppression and interception of mailard reaction
GB2279650A (en) * 1992-12-28 1995-01-11 Agency Ind Science Techn Process for isomerization of compound of aldose structure into compound of ketose structure,and isomerization agent or accelerator used therein
GB2279650B (en) * 1992-12-28 1996-11-20 Jp National Food Research Inst Process for isomerization of compound of aldose structure into compound of ketose structure,and isomerization agent or accelerator used therein

Also Published As

Publication number Publication date
JPS6228797B2 (en) 1987-06-23

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