JPS565496A - Antibiotic c-19393h2 and its preparation - Google Patents
Antibiotic c-19393h2 and its preparationInfo
- Publication number
- JPS565496A JPS565496A JP8114179A JP8114179A JPS565496A JP S565496 A JPS565496 A JP S565496A JP 8114179 A JP8114179 A JP 8114179A JP 8114179 A JP8114179 A JP 8114179A JP S565496 A JPS565496 A JP S565496A
- Authority
- JP
- Japan
- Prior art keywords
- positive
- streptomyces
- gram
- antibiotic
- negative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- FWWJFXYMDLTDNO-BBCPMLLOSA-N (5r,6r)-3-[(r)-[(e)-2-acetamidoethenyl]sulfinyl]-6-(2-hydroxypropan-2-yl)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid Chemical compound C1C([S@](=O)/C=C/NC(=O)C)=C(C(O)=O)N2C(=O)[C@@H](C(C)(C)O)[C@@H]12 FWWJFXYMDLTDNO-BBCPMLLOSA-N 0.000 title abstract 2
- 238000006243 chemical reaction Methods 0.000 abstract 2
- 241000894006 Bacteria Species 0.000 abstract 1
- 229910021578 Iron(III) chloride Inorganic materials 0.000 abstract 1
- 241000187747 Streptomyces Species 0.000 abstract 1
- 241000187180 Streptomyces sp. Species 0.000 abstract 1
- 230000002378 acidificating effect Effects 0.000 abstract 1
- 238000005273 aeration Methods 0.000 abstract 1
- 238000004458 analytical method Methods 0.000 abstract 1
- 230000000845 anti-microbial effect Effects 0.000 abstract 1
- 239000004599 antimicrobial Substances 0.000 abstract 1
- 239000001963 growth medium Substances 0.000 abstract 1
- RBTARNINKXHZNM-UHFFFAOYSA-K iron trichloride Chemical compound Cl[Fe](Cl)Cl RBTARNINKXHZNM-UHFFFAOYSA-K 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- FEMOMIGRRWSMCU-UHFFFAOYSA-N ninhydrin Chemical compound C1=CC=C2C(=O)C(O)(O)C(=O)C2=C1 FEMOMIGRRWSMCU-UHFFFAOYSA-N 0.000 abstract 1
- 239000012286 potassium permanganate Substances 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000012834 spinner culture method Methods 0.000 abstract 1
- 239000006228 supernatant Substances 0.000 abstract 1
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Compounds Of Unknown Constitution (AREA)
Abstract
NEW MATERIAL:A water-soluble acidic antibiotic C-19393H2 and its salt having the following properties: 1) White powder. 2) Elementary analysis C, 45.34±1.0; H, 4.98±0.5; N, 7.48±0.5, Na, 6.15±1.0; S, 8.51±1.0. 3) Molecular weight 426W322 calculated as one Na in one molecule. 4) Positive to Ehrlich's reaction and KMnO4; negative to ninhydrin, ferric chloride and Sakaguchi's reactions.
USE: An antimicrobial against Gram-positive and Gram-negative bacteria.
PROCESS: A strain of Streptomyces sp.IFO 13886 (FERM-P No.4774) belonging to the genus Streptomyces is incubated in a culture medium by the spinner culture method with aeration at 15W32°C and pH4W8 for 24W144hr. The resulting supernatant liquid is collected and purified.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (16)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP8114179A JPS565496A (en) | 1979-06-26 | 1979-06-26 | Antibiotic c-19393h2 and its preparation |
| AU54518/80A AU534530B2 (en) | 1979-02-02 | 1980-01-10 | 5-aza-(3.2.0)-heptane derivatives |
| DK12580A DK12580A (en) | 1979-02-02 | 1980-01-11 | ANTIBIOTICS C-19393S2 AND H2 |
| US06/113,132 US4518529A (en) | 1979-02-02 | 1980-01-17 | Antibiotics C-19393S2 |
| PT70710A PT70710A (en) | 1979-02-02 | 1980-01-18 | Antibiotics c-19393 s2 and h2 |
| CH67680A CH646432A5 (en) | 1979-02-02 | 1980-01-28 | BETA LACTAM ANTIBIOTICS. |
| HU80180A HU181721B (en) | 1979-02-02 | 1980-01-28 | Process for preparing antibiotics c-19393sdown 2 and c-1939hdown 2 |
| FR8002162A FR2447922A1 (en) | 1979-02-02 | 1980-01-31 | ANTIBIOTICS C-19393 S2 AND C-19393 H2 AND THEIR SALTS, THEIR PREPARATION METHOD FROM MICROORGANISMS OF THE STREPTOMYCE GENUS AND THEIR USE IN MEDICINAL PREPARATIONS |
| ES488836A ES8102590A1 (en) | 1979-02-02 | 1980-01-31 | Antibiotics C-19393S2 +B |
| NL8000628A NL8000628A (en) | 1979-02-02 | 1980-01-31 | ANTIBIOTICS C-19393S2 AND H2. |
| SU802878699A SU1075984A3 (en) | 1979-02-02 | 1980-02-01 | Process for preparing antibiotic c-19393 s2 and/or c-19393 h2 |
| SE8000842A SE8000842L (en) | 1979-02-02 | 1980-02-01 | NEW ANTIBIOTICS |
| GB8003402A GB2042532B (en) | 1979-02-02 | 1980-02-01 | Antibiotics c-19393 s2 and 'i |
| IT19645/80A IT1130246B (en) | 1979-02-02 | 1980-02-01 | ANTIBIOTIC AND MICROBIOLOGICAL PROCEDURE TO PRODUCE IT |
| DE19803003624 DE3003624A1 (en) | 1979-02-02 | 1980-02-01 | ANTIBIOTICA C-19393 S LOW 2 AND H LOW 2 |
| PH23567A PH14316A (en) | 1979-02-02 | 1980-02-01 | Antibiotics c-19393 s2 and h2 and method of preparation thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP8114179A JPS565496A (en) | 1979-06-26 | 1979-06-26 | Antibiotic c-19393h2 and its preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS565496A true JPS565496A (en) | 1981-01-20 |
Family
ID=13738122
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP8114179A Pending JPS565496A (en) | 1979-02-02 | 1979-06-26 | Antibiotic c-19393h2 and its preparation |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS565496A (en) |
-
1979
- 1979-06-26 JP JP8114179A patent/JPS565496A/en active Pending
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