JPS5679643A - 2,2-dialkoxycyclohexyl acetate and its preparation - Google Patents
2,2-dialkoxycyclohexyl acetate and its preparationInfo
- Publication number
- JPS5679643A JPS5679643A JP15635479A JP15635479A JPS5679643A JP S5679643 A JPS5679643 A JP S5679643A JP 15635479 A JP15635479 A JP 15635479A JP 15635479 A JP15635479 A JP 15635479A JP S5679643 A JPS5679643 A JP S5679643A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- acetate
- expressed
- cyclohexanone
- dialkoxycyclohexyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
NEW MATERIAL:A 2,2-dialkoxycyclohexylacetate expressed by formula I (R1 and R2 are lower alkyl).
EXAMPLE: Ethyl 2,2-diethoxycyclohexylacetate.
USE: A synthetic intermediate for a medicine, e.g. Diclofenac Sodium having pharamacological effects, e.g. an anti-inflammatory, an analgesic and an antipyretic effects.
PROCESS: A cyclohexanone-2-acetate expressed by formula II is reacted with an orthoformic ester expressed by the formula HC(OR2)3 in a molar amount of 1W2 times that of the cyclohexanone-2-acetate, preferably in a little excess, preferably in the presence of an cid catalyst, at a temperature in the range of 0°C to the boiling point of the orthoformic ester, to give a compound of formula I.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP15635479A JPS5679643A (en) | 1979-12-04 | 1979-12-04 | 2,2-dialkoxycyclohexyl acetate and its preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP15635479A JPS5679643A (en) | 1979-12-04 | 1979-12-04 | 2,2-dialkoxycyclohexyl acetate and its preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5679643A true JPS5679643A (en) | 1981-06-30 |
| JPS6312859B2 JPS6312859B2 (en) | 1988-03-23 |
Family
ID=15625915
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP15635479A Granted JPS5679643A (en) | 1979-12-04 | 1979-12-04 | 2,2-dialkoxycyclohexyl acetate and its preparation |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5679643A (en) |
-
1979
- 1979-12-04 JP JP15635479A patent/JPS5679643A/en active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6312859B2 (en) | 1988-03-23 |
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