JPS57179122A - Blood coagulation factor ix preparation for oral administration - Google Patents

Blood coagulation factor ix preparation for oral administration

Info

Publication number: JPS57179122A
Authority: JP; Japan
Prior art keywords: blood coagulation; coagulation factor; liposome; contents; preparation
Prior art date: 1981-04-28
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

JP56065685A

Other languages

English (en)

Japanese (ja)

Other versions

JPH03851B2 (th

Inventor

Isamu Horikoshi

Nobuo Sakuragawa

Masaharu Ueno

Kaoru Takahashi

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Individual

Original Assignee

Individual

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1981-04-28

Filing date

1981-04-28

Publication date

1982-11-04

1981-04-28 Application filed by Individual filed Critical Individual

1981-04-28 Priority to JP56065685A priority Critical patent/JPS57179122A/ja

1981-10-07 Priority to US06/309,269 priority patent/US4348384A/en

1982-11-04 Publication of JPS57179122A publication Critical patent/JPS57179122A/ja

1991-01-09 Publication of JPH03851B2 publication Critical patent/JPH03851B2/ja

Status Granted legal-status Critical Current

Links

108010076282 Factor IX Proteins 0.000 title abstract 4
238000002360 preparation method Methods 0.000 title abstract 2
239000002775 capsule Substances 0.000 abstract 4
239000002502 liposome Substances 0.000 abstract 4
239000003795 chemical substances by application Substances 0.000 abstract 3
229940124158 Protease/peptidase inhibitor Drugs 0.000 abstract 2
238000010521 absorption reaction Methods 0.000 abstract 2
238000000354 decomposition reaction Methods 0.000 abstract 2
239000000137 peptide hydrolase inhibitor Substances 0.000 abstract 2
108010039627 Aprotinin Proteins 0.000 abstract 1
108010039209 Blood Coagulation Factors Proteins 0.000 abstract 1
102000015081 Blood Coagulation Factors Human genes 0.000 abstract 1
208000031220 Hemophilia Diseases 0.000 abstract 1
208000009292 Hemophilia A Diseases 0.000 abstract 1
108091005804 Peptidases Proteins 0.000 abstract 1
239000004365 Protease Substances 0.000 abstract 1
102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 abstract 1
229960004405 aprotinin Drugs 0.000 abstract 1
239000003114 blood coagulation factor Substances 0.000 abstract 1
229940019700 blood coagulation factors Drugs 0.000 abstract 1
230000009849 deactivation Effects 0.000 abstract 1
230000002401 inhibitory effect Effects 0.000 abstract 1
ZPNFWUPYTFPOJU-LPYSRVMUSA-N iniprol Chemical compound C([C@H]1C(=O)NCC(=O)NCC(=O)N[C@H]2CSSC[C@H]3C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](C(N[C@H](C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=4C=CC(O)=CC=4)C(=O)N[C@@H](CC=4C=CC=CC=4)C(=O)N[C@@H](CC=4C=CC(O)=CC=4)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CSSC[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC=4C=CC=CC=4)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC2=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CSSC[C@H](NC(=O)[C@H](CC=2C=CC=CC=2)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H]2N(CCC2)C(=O)[C@@H](N)CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N2[C@@H](CCC2)C(=O)N2[C@@H](CCC2)C(=O)N[C@@H](CC=2C=CC(O)=CC=2)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N2[C@@H](CCC2)C(=O)N3)C(=O)NCC(=O)NCC(=O)N[C@@H](C)C(O)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@H](C(=O)N1)C(C)C)[C@@H](C)O)[C@@H](C)CC)=O)[C@@H](C)CC)C1=CC=C(O)C=C1 ZPNFWUPYTFPOJU-LPYSRVMUSA-N 0.000 abstract 1
239000000463 material Substances 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
210000000813 small intestine Anatomy 0.000 abstract 1

Landscapes

Medicinal Preparation (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

JP56065685A 1980-10-17 1981-04-28 Blood coagulation factor ix preparation for oral administration Granted JPS57179122A (en)

Priority Applications (2)

Application Number	Priority Date	Filing Date	Title
JP56065685A JPS57179122A (en)	1981-04-28	1981-04-28	Blood coagulation factor ix preparation for oral administration
US06/309,269 US4348384A (en)	1980-10-17	1981-10-07	Pharmaceutical composition for oral administration containing coagulation factor VIII or IX

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP56065685A JPS57179122A (en)	1981-04-28	1981-04-28	Blood coagulation factor ix preparation for oral administration

Publications (2)

Publication Number	Publication Date
JPS57179122A true JPS57179122A (en)	1982-11-04
JPH03851B2 JPH03851B2 (th)	1991-01-09

Family

ID=13294104

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP56065685A Granted JPS57179122A (en)	1980-10-17	1981-04-28	Blood coagulation factor ix preparation for oral administration

Country Status (1)

Country	Link
JP (1)	JPS57179122A (th)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS60188328A (ja) *	1984-02-07	1985-09-25	インターフエロン・サイエンシズ・インコーポレーテツド	インターフエロン投与用ビヒクル
WO1995022981A1 (en) *	1994-02-24	1995-08-31	Nippon Chemiphar Co., Ltd.	Oral synthetic peptide preparation
JP2001514209A (ja) *	1997-09-04	2001-09-11	バイオゾーンラボラトリーズ，インコーポレイテッド	経口リポソーム送達系

1981
- 1981-04-28 JP JP56065685A patent/JPS57179122A/ja active Granted

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS60188328A (ja) *	1984-02-07	1985-09-25	インターフエロン・サイエンシズ・インコーポレーテツド	インターフエロン投与用ビヒクル
WO1995022981A1 (en) *	1994-02-24	1995-08-31	Nippon Chemiphar Co., Ltd.	Oral synthetic peptide preparation
JP2001514209A (ja) *	1997-09-04	2001-09-11	バイオゾーンラボラトリーズ，インコーポレイテッド	経口リポソーム送達系
JP2010001317A (ja) *	1997-09-04	2010-01-07	Biozone Lab Inc	経口リポソーム送達系

Also Published As

Publication number	Publication date
JPH03851B2 (th)	1991-01-09

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