JPS57197284A - Alpha-tocopheryl nicotinate metal complex, its preparation, and remedy for arteriosclerosis comprising it as active ingredient - Google Patents

Alpha-tocopheryl nicotinate metal complex, its preparation, and remedy for arteriosclerosis comprising it as active ingredient

Info

Publication number: JPS57197284A
Authority: JP; Japan
Prior art keywords: tocopheryl nicotinate; arteriosclerosis; remedy; copper; compound shown
Prior art date: 1981-05-29
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

JP8116381A

Other languages

English (en)

Japanese (ja)

Other versions

JPS6326760B2 (de

Inventor

Eiichi Suenaga

Kenji Miura

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Sanwa Kagaku Kenkyusho Co Ltd

Original Assignee

Sanwa Kagaku Kenkyusho Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1981-05-29

Filing date

1981-05-29

Publication date

1982-12-03

1981-05-29 Application filed by Sanwa Kagaku Kenkyusho Co Ltd filed Critical Sanwa Kagaku Kenkyusho Co Ltd

1981-05-29 Priority to JP8116381A priority Critical patent/JPS57197284A/ja

1982-12-03 Publication of JPS57197284A publication Critical patent/JPS57197284A/ja

1988-05-31 Publication of JPS6326760B2 publication Critical patent/JPS6326760B2/ja

Status Granted legal-status Critical Current

Links

-1 Alpha-tocopheryl nicotinate metal complex Chemical class 0.000 title abstract 2
206010003210 Arteriosclerosis Diseases 0.000 title abstract 2
208000011775 arteriosclerosis disease Diseases 0.000 title abstract 2
239000004480 active ingredient Substances 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 3
229910052751 metal Inorganic materials 0.000 abstract 3
239000002184 metal Substances 0.000 abstract 3
VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 2
XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 abstract 2
MSCCTZZBYHQMQJ-AZAGJHQNSA-N Tocopheryl nicotinate Chemical compound C([C@@](OC1=C(C)C=2C)(C)CCC[C@H](C)CCC[C@H](C)CCCC(C)C)CC1=C(C)C=2OC(=O)C1=CC=CN=C1 MSCCTZZBYHQMQJ-AZAGJHQNSA-N 0.000 abstract 2
239000010949 copper Substances 0.000 abstract 2
150000003839 salts Chemical class 0.000 abstract 2
BMYNFMYTOJXKLE-UHFFFAOYSA-N 3-azaniumyl-2-hydroxypropanoate Chemical compound NCC(O)C(O)=O BMYNFMYTOJXKLE-UHFFFAOYSA-N 0.000 abstract 1
RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 abstract 1
HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 abstract 1
150000001450 anions Chemical class 0.000 abstract 1
229910017052 cobalt Inorganic materials 0.000 abstract 1
239000010941 cobalt Substances 0.000 abstract 1
GUTLYIVDDKVIGB-UHFFFAOYSA-N cobalt atom Chemical compound [Co] GUTLYIVDDKVIGB-UHFFFAOYSA-N 0.000 abstract 1
229910052802 copper Inorganic materials 0.000 abstract 1
229910000365 copper sulfate Inorganic materials 0.000 abstract 1
ORTQZVOHEJQUHG-UHFFFAOYSA-L copper(II) chloride Chemical compound Cl[Cu]Cl ORTQZVOHEJQUHG-UHFFFAOYSA-L 0.000 abstract 1
ARUVKPQLZAKDPS-UHFFFAOYSA-L copper(II) sulfate Chemical compound [Cu+2].[O-][S+2]([O-])([O-])[O-] ARUVKPQLZAKDPS-UHFFFAOYSA-L 0.000 abstract 1
OPQARKPSCNTWTJ-UHFFFAOYSA-L copper(ii) acetate Chemical compound [Cu+2].CC([O-])=O.CC([O-])=O OPQARKPSCNTWTJ-UHFFFAOYSA-L 0.000 abstract 1
229910052742 iron Inorganic materials 0.000 abstract 1
WPBNNNQJVZRUHP-UHFFFAOYSA-L manganese(2+);methyl n-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate;n-[2-(sulfidocarbothioylamino)ethyl]carbamodithioate Chemical compound [Mn+2].[S-]C(=S)NCCNC([S-])=S.COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC WPBNNNQJVZRUHP-UHFFFAOYSA-L 0.000 abstract 1
239000000463 material Substances 0.000 abstract 1
238000002844 melting Methods 0.000 abstract 1
230000008018 melting Effects 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
239000000825 pharmaceutical preparation Substances 0.000 abstract 1
239000002904 solvent Substances 0.000 abstract 1
239000011701 zinc Substances 0.000 abstract 1
229910052725 zinc Inorganic materials 0.000 abstract 1

Landscapes

Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

JP8116381A 1981-05-29 1981-05-29 Alpha-tocopheryl nicotinate metal complex, its preparation, and remedy for arteriosclerosis comprising it as active ingredient Granted JPS57197284A (en)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
JP8116381A JPS57197284A (en)	1981-05-29	1981-05-29	Alpha-tocopheryl nicotinate metal complex, its preparation, and remedy for arteriosclerosis comprising it as active ingredient

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP8116381A JPS57197284A (en)	1981-05-29	1981-05-29	Alpha-tocopheryl nicotinate metal complex, its preparation, and remedy for arteriosclerosis comprising it as active ingredient

Publications (2)

Publication Number	Publication Date
JPS57197284A true JPS57197284A (en)	1982-12-03
JPS6326760B2 JPS6326760B2 (de)	1988-05-31

Family

ID=13738781

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP8116381A Granted JPS57197284A (en)	1981-05-29	1981-05-29	Alpha-tocopheryl nicotinate metal complex, its preparation, and remedy for arteriosclerosis comprising it as active ingredient

Country Status (1)

Country	Link
JP (1)	JPS57197284A (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0347864A3 (de) *	1988-06-24	1992-04-01	Andries Johannes Cornelus Strydom	Antiatherosklerose-Mittel

1981
- 1981-05-29 JP JP8116381A patent/JPS57197284A/ja active Granted

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0347864A3 (de) *	1988-06-24	1992-04-01	Andries Johannes Cornelus Strydom	Antiatherosklerose-Mittel

Also Published As

Publication number	Publication date
JPS6326760B2 (de)	1988-05-31

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