JPS5750970A - Preparation of 5-ureidohydantoin - Google Patents

Preparation of 5-ureidohydantoin

Info

Publication number
JPS5750970A
JPS5750970A JP12608480A JP12608480A JPS5750970A JP S5750970 A JPS5750970 A JP S5750970A JP 12608480 A JP12608480 A JP 12608480A JP 12608480 A JP12608480 A JP 12608480A JP S5750970 A JPS5750970 A JP S5750970A
Authority
JP
Japan
Prior art keywords
compound
formula
condensation agent
pref
urea
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP12608480A
Other languages
Japanese (ja)
Other versions
JPH0233033B2 (en
Inventor
Kiyonori Yokogoshi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PAAMAKEMU ASIA KK
Permachem Asia Ltd
Original Assignee
PAAMAKEMU ASIA KK
Permachem Asia Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PAAMAKEMU ASIA KK, Permachem Asia Ltd filed Critical PAAMAKEMU ASIA KK
Priority to JP12608480A priority Critical patent/JPS5750970A/en
Publication of JPS5750970A publication Critical patent/JPS5750970A/en
Publication of JPH0233033B2 publication Critical patent/JPH0233033B2/ja
Granted legal-status Critical Current

Links

Abstract

PURPOSE: To prepare the titled substance useful as a remedy and preventive for ulcer in itself or in the form of an aluminum derivative and administable without side-effect, in high purity and yield, by reacting a glyoxylic acid ester with urea in the presence of a condensation agent.
CONSTITUTION: The compound of formula I (R is alkyl, aryl, aralkyl or acetyl) is reacted with urea in the presence of a condensation agent (e.g. mineral acid, thiohalide, inorganic alkali, alcoholate, etc.) at 55W85°C to obtain the compound of formula II. The amount of the condensation agent is pref. 0.5W4.0 equivalent per 1 equivalent of the compound of formula I, and the reaction is pref. carried out in the presence of a polar solvent such as water, alcohol, glycol, acetonitrile, DMF, etc.
COPYRIGHT: (C)1982,JPO&Japio
JP12608480A 1980-09-12 1980-09-12 Preparation of 5-ureidohydantoin Granted JPS5750970A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP12608480A JPS5750970A (en) 1980-09-12 1980-09-12 Preparation of 5-ureidohydantoin

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP12608480A JPS5750970A (en) 1980-09-12 1980-09-12 Preparation of 5-ureidohydantoin

Publications (2)

Publication Number Publication Date
JPS5750970A true JPS5750970A (en) 1982-03-25
JPH0233033B2 JPH0233033B2 (en) 1990-07-25

Family

ID=14926201

Family Applications (1)

Application Number Title Priority Date Filing Date
JP12608480A Granted JPS5750970A (en) 1980-09-12 1980-09-12 Preparation of 5-ureidohydantoin

Country Status (1)

Country Link
JP (1) JPS5750970A (en)

Also Published As

Publication number Publication date
JPH0233033B2 (en) 1990-07-25

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