JPS5777625A - Adsorbent for rheumatoid factor and apparatus for removing rheumatoid factor - Google Patents
Adsorbent for rheumatoid factor and apparatus for removing rheumatoid factorInfo
- Publication number
- JPS5777625A JPS5777625A JP15218480A JP15218480A JPS5777625A JP S5777625 A JPS5777625 A JP S5777625A JP 15218480 A JP15218480 A JP 15218480A JP 15218480 A JP15218480 A JP 15218480A JP S5777625 A JPS5777625 A JP S5777625A
- Authority
- JP
- Japan
- Prior art keywords
- rheumatoid factor
- adsorbent
- fluid
- immunoglobulin
- safe
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003463 adsorbent Substances 0.000 title abstract 5
- 208000027932 Collagen disease Diseases 0.000 abstract 2
- 230000003297 denaturating effect Effects 0.000 abstract 2
- 239000012530 fluid Substances 0.000 abstract 2
- 229940027941 immunoglobulin g Drugs 0.000 abstract 2
- 239000000126 substance Substances 0.000 abstract 2
- JOYRKODLDBILNP-UHFFFAOYSA-N Ethyl urethane Chemical compound CCOC(N)=O JOYRKODLDBILNP-UHFFFAOYSA-N 0.000 abstract 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 210000001124 body fluid Anatomy 0.000 abstract 1
- 239000010839 body fluid Substances 0.000 abstract 1
- 239000004202 carbamide Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000036425 denaturation Effects 0.000 abstract 1
- 238000004925 denaturation Methods 0.000 abstract 1
- 238000001179 sorption measurement Methods 0.000 abstract 1
Landscapes
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
PURPOSE: To provide a rheumatoid factor adsorbent by denaturating an immunoglobulin G-containing substance fixed to a carrier, and to provide a safe and sure treating apparatus for collagen disease, composed of a container having an inlet and an outlet of fluid and containing said adsorbent.
CONSTITUTION: An immunoglobulin G-containing substance is fixed to an inert carrier through covalent bonds, and denaturated to obtain a rheumatoid factor adsorbent. The denaturation is carried out, e.g. with heat, denaturating agent such as urea, urethane, etc., or physical means such as irradiation with UV-light, X-ray, etc. The adsorvent is packed in a container having an inlet and an outlet of fluid to obtain the rheumatoid factor removing apparatus. The adsorbent thus obtained is extremely effective for the adsorption and removal of rheumatoid factor from the body fluid (e.g. blood, plasma, etc.), and useful for the remedy of collagen disease, etc. Furthermore, the apparatus is very compact, simple, and safe.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP15218480A JPS5777625A (en) | 1980-10-31 | 1980-10-31 | Adsorbent for rheumatoid factor and apparatus for removing rheumatoid factor |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP15218480A JPS5777625A (en) | 1980-10-31 | 1980-10-31 | Adsorbent for rheumatoid factor and apparatus for removing rheumatoid factor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS5777625A true JPS5777625A (en) | 1982-05-15 |
Family
ID=15534886
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP15218480A Pending JPS5777625A (en) | 1980-10-31 | 1980-10-31 | Adsorbent for rheumatoid factor and apparatus for removing rheumatoid factor |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5777625A (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5940862A (en) * | 1982-08-30 | 1984-03-06 | テルモ株式会社 | Rheumatoid factor adsorbent and production thereof |
| JPS5949773A (en) * | 1982-08-12 | 1984-03-22 | 鐘淵化学工業株式会社 | Activation of biologically compatible polymer by biological drug using phatological operating body as binding compliance |
| JPS59141524A (en) * | 1983-02-03 | 1984-08-14 | Terumo Corp | Antibody adsorbent |
| US4705628A (en) * | 1985-04-09 | 1987-11-10 | Terumo Kabushiki Kaisha | Immunoglobulin adsorbent and adsorption apparatus |
| WO2009123148A1 (en) * | 2008-03-31 | 2009-10-08 | 旭化成せんい株式会社 | Cellulose derivative fine particles, fluid dispersions of the same, solid dispersions thereof, and diagnostic drugs |
| CN109342743A (en) * | 2018-12-05 | 2019-02-15 | 菲鹏生物股份有限公司 | A kind of preparation method for the denaturation IgG that can be efficiently combined with rheumatoid factor |
-
1980
- 1980-10-31 JP JP15218480A patent/JPS5777625A/en active Pending
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5949773A (en) * | 1982-08-12 | 1984-03-22 | 鐘淵化学工業株式会社 | Activation of biologically compatible polymer by biological drug using phatological operating body as binding compliance |
| JPS5940862A (en) * | 1982-08-30 | 1984-03-06 | テルモ株式会社 | Rheumatoid factor adsorbent and production thereof |
| JPS59141524A (en) * | 1983-02-03 | 1984-08-14 | Terumo Corp | Antibody adsorbent |
| US4705628A (en) * | 1985-04-09 | 1987-11-10 | Terumo Kabushiki Kaisha | Immunoglobulin adsorbent and adsorption apparatus |
| WO2009123148A1 (en) * | 2008-03-31 | 2009-10-08 | 旭化成せんい株式会社 | Cellulose derivative fine particles, fluid dispersions of the same, solid dispersions thereof, and diagnostic drugs |
| JP2015083696A (en) * | 2008-03-31 | 2015-04-30 | 旭化成せんい株式会社 | Cellulose derivative fine particle, liquid dispersion and dispersoid thereof, and diagnostic |
| US9096690B2 (en) | 2008-03-31 | 2015-08-04 | Asahi Kasei Fibers Corporation | Cellulose derivative fine particle, dispersion liquid thereof, dispersion body thereof and diagnostic reagent |
| US9341622B2 (en) | 2008-03-31 | 2016-05-17 | Asahi Kasei Fibers Corporation | Cellulose derivative fine particle, dispersion liquid thereof, dispersion body thereof and diagnostic reagent |
| JP5952522B2 (en) * | 2008-03-31 | 2016-07-13 | 旭化成株式会社 | Cellulose derivative fine particles, dispersion thereof, dispersion thereof and diagnostic agent |
| CN109342743A (en) * | 2018-12-05 | 2019-02-15 | 菲鹏生物股份有限公司 | A kind of preparation method for the denaturation IgG that can be efficiently combined with rheumatoid factor |
| CN109342743B (en) * | 2018-12-05 | 2022-02-18 | 菲鹏生物股份有限公司 | Preparation method of denatured IgG capable of being efficiently combined with rheumatoid factor |
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