JPS58180484A - １−置換Ｎ−／８α−エルゴリニル／−Ｎ′，Ｎ′−ジエチルウレア及びその製造方法 - Google Patents

１−置換Ｎ−／８α−エルゴリニル／−Ｎ′，Ｎ′−ジエチルウレア及びその製造方法

Info

Publication number
JPS58180484A
JPS58180484A JP58039349A JP3934983A JPS58180484A JP S58180484 A JPS58180484 A JP S58180484A JP 58039349 A JP58039349 A JP 58039349A JP 3934983 A JP3934983 A JP 3934983A JP S58180484 A JPS58180484 A JP S58180484A
Authority
JP
Japan
Prior art keywords
ergolinyl
general formula
diethylurea
methyl
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP58039349A
Other languages
English (en)
Japanese (ja)
Inventor
アントニン・チエルニイ
ユリ・クレペルカ
カレル・レザベク
ミロスラフ・セダ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Spofa Spojene Podniky Pro Zdravotnickou Vyrobu
Original Assignee
Spofa Spojene Podniky Pro Zdravotnickou Vyrobu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Spofa Spojene Podniky Pro Zdravotnickou Vyrobu filed Critical Spofa Spojene Podniky Pro Zdravotnickou Vyrobu
Publication of JPS58180484A publication Critical patent/JPS58180484A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/10—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hetero atoms directly attached in position 8
    • C07D457/12—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Endocrinology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP58039349A 1982-03-12 1983-03-11 １−置換Ｎ−／８α−エルゴリニル／−Ｎ′，Ｎ′−ジエチルウレア及びその製造方法 Pending JPS58180484A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CS821734A CS231214B1 (en) 1982-03-12 1982-03-12 Processing method of 1-substituted n+l8alpha-ergoline+p-n,diethyl urea
CS173482 1982-03-12

Publications (1)

Publication Number Publication Date
JPS58180484A true JPS58180484A (ja) 1983-10-21

Family

ID=5352449

Family Applications (1)

Application Number Title Priority Date Filing Date
JP58039349A Pending JPS58180484A (ja) 1982-03-12 1983-03-11 １−置換Ｎ−／８α−エルゴリニル／−Ｎ′，Ｎ′−ジエチルウレア及びその製造方法

Country Status (15)

Country Link
JP (1) JPS58180484A (de)
AT (1) AT383349B (de)
AU (1) AU555961B2 (de)
BE (1) BE896122A (de)
CA (1) CA1203531A (de)
CH (1) CH652125A5 (de)
CS (1) CS231214B1 (de)
DE (1) DE3308719A1 (de)
DK (1) DK84683A (de)
FI (1) FI830754L (de)
FR (1) FR2523131B1 (de)
GB (1) GB2116548B (de)
IT (1) IT1161209B (de)
NL (1) NL8300829A (de)
SE (1) SE452321B (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59176285A (ja) * 1983-03-14 1984-10-05 シエ−リング・アクチエンゲゼルシヤフト 新規の置換エルゴリン、その製法および該化合物を含有する、中枢神経系に対して作用を有する医薬

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0208417A3 (de) * 1985-06-12 1989-09-06 SPOFA Spojené Podniky Pro Zdravotnickou Vyrobu Verwendung von 1-(8alpha-Ergolinyl)-3,3-diethylureaderivaten zur Behandlung von Endometritis
DE3522894A1 (de) * 1985-06-24 1987-01-02 Schering Ag Verwendung von tergurid als geriatrikum
FR2584720B1 (fr) * 1985-07-11 1987-10-02 Rhone Poulenc Sante Procede de preparation de derives n-methyles de l'ergoline
DE3620293A1 (de) * 1986-06-16 1987-12-17 Schering Ag 1-und/oder 2-substituierte ergolinderivate
DE3623503A1 (de) * 1986-07-09 1988-01-21 Schering Ag 1-aryl-ergolinyl-harnstoffderivate, verfahren zu deren herstellung sowie die verwendung dieser verbindungen als arzneimittel
DE10212564B4 (de) * 2002-03-12 2007-04-19 Neurobiotec Gmbh 1-Allyl-ergotalkaloid-Derivate und ihre Verwendung zur Prophylaxe und Therapie von Migräne
BR112013011640A2 (pt) * 2010-11-11 2017-10-10 Sinoxa Pharma Ug lisurida, tergurida e derivados das mesmas para o uso na profilaxia e/ou na terapia de alterações fibróticas
MX2017009405A (es) 2015-01-20 2018-01-18 Xoc Pharmaceuticals Inc Compuestos de tipo ergolina y usos de estos.
EP3247357A4 (de) 2015-01-20 2018-07-11 Xoc Pharmaceuticals, Inc Isoergolinverbindungen und verwendungen davon
WO2018223065A1 (en) 2017-06-01 2018-12-06 Xoc Pharmaceuticals, Inc. Ergoline derivatives for use in medicine

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH344731A (de) * 1956-05-18 1960-02-29 Sandoz Ag Verfahren zur Herstellung von neuen, am Indolstickstoff alkylierten Derivaten der Lysergsäure-Reihe
AT231082B (de) * 1960-10-12 1964-01-10 Sandoz Ag Verfahren zur Herstellung von neuen Harnstoff-Derivaten
EP0021206B1 (de) * 1979-06-13 1983-06-22 Schering Aktiengesellschaft Neue (Ergolin-yl)-N', N'-diäthylharnstoff-Derivate, ihre Herstellung und sie enthaltende Arzneimittel

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59176285A (ja) * 1983-03-14 1984-10-05 シエ−リング・アクチエンゲゼルシヤフト 新規の置換エルゴリン、その製法および該化合物を含有する、中枢神経系に対して作用を有する医薬

Also Published As

Publication number Publication date
SE452321B (sv) 1987-11-23
FI830754A7 (fi) 1983-09-13
DK84683A (da) 1983-09-13
GB2116548A (en) 1983-09-28
CA1203531A (en) 1986-04-22
SE8301257D0 (sv) 1983-03-08
GB2116548B (en) 1985-03-20
SE8301257L (sv) 1983-09-13
GB8305735D0 (en) 1983-04-07
FR2523131B1 (fr) 1987-08-28
FI830754L (fi) 1983-09-13
BE896122A (fr) 1983-07-01
ATA72783A (de) 1986-11-15
FR2523131A1 (fr) 1983-09-16
CH652125A5 (de) 1985-10-31
IT1161209B (it) 1987-03-18
AT383349B (de) 1987-06-25
AU1216783A (en) 1983-09-15
AU555961B2 (en) 1986-10-16
CS231214B1 (en) 1984-10-15
IT8319935A0 (it) 1983-03-07
DK84683D0 (da) 1983-02-24
DE3308719A1 (de) 1983-09-22
FI830754A0 (fi) 1983-03-07
NL8300829A (nl) 1983-10-03

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