JPS58188847A - ペプチド誘導体 - Google Patents

ペプチド誘導体

Info

Publication number
JPS58188847A
JPS58188847A JP57069897A JP6989782A JPS58188847A JP S58188847 A JPS58188847 A JP S58188847A JP 57069897 A JP57069897 A JP 57069897A JP 6989782 A JP6989782 A JP 6989782A JP S58188847 A JPS58188847 A JP S58188847A
Authority
JP
Japan
Prior art keywords
group
formula
compound
reaction
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP57069897A
Other languages
English (en)
Japanese (ja)
Other versions
JPH031319B2 (2
Inventor
Yoshikazu Oka
岡　良和
Kohei Nishikawa
浩平 西川
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Priority to JP57069897A priority Critical patent/JPS58188847A/ja
Priority to DE8383302120T priority patent/DE3373480D1/de
Priority to EP83302120A priority patent/EP0092942B1/en
Priority to US06/485,824 priority patent/US4472383A/en
Priority to CA000426595A priority patent/CA1241644A/en
Publication of JPS58188847A publication Critical patent/JPS58188847A/ja
Publication of JPH031319B2 publication Critical patent/JPH031319B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP57069897A 1982-04-26 1982-04-26 ペプチド誘導体 Granted JPS58188847A (ja)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP57069897A JPS58188847A (ja) 1982-04-26 1982-04-26 ペプチド誘導体
DE8383302120T DE3373480D1 (en) 1982-04-26 1983-04-14 Peptide derivatives, their production and use
EP83302120A EP0092942B1 (en) 1982-04-26 1983-04-14 Peptide derivatives, their production and use
US06/485,824 US4472383A (en) 1982-04-26 1983-04-18 Peptide derivatives, their production and use
CA000426595A CA1241644A (en) 1982-04-26 1983-04-25 Peptide derivatives, their production and use

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP57069897A JPS58188847A (ja) 1982-04-26 1982-04-26 ペプチド誘導体

Publications (2)

Publication Number Publication Date
JPS58188847A true JPS58188847A (ja) 1983-11-04
JPH031319B2 JPH031319B2 (2) 1991-01-10

Family

ID=13415948

Family Applications (1)

Application Number Title Priority Date Filing Date
JP57069897A Granted JPS58188847A (ja) 1982-04-26 1982-04-26 ペプチド誘導体

Country Status (5)

Country Link
US (1) US4472383A (2)
EP (1) EP0092942B1 (2)
JP (1) JPS58188847A (2)
CA (1) CA1241644A (2)
DE (1) DE3373480D1 (2)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4595675A (en) * 1979-09-19 1986-06-17 Hoechst Aktiengesellschaft Bicyclic α-iminocarboxylic acid compounds having hypotensive activity
US4610816A (en) * 1980-12-18 1986-09-09 Schering Corporation Substituted dipeptides as inhibitors of enkephalinases
US4906615A (en) * 1980-12-18 1990-03-06 Schering Corporation Substituted dipeptides as inhibitors of enkephalinases
EP0284510A3 (en) * 1987-03-24 1990-08-22 Asahi Breweries, Ltd. N-[N alpha-(1(S)-carboxy-3-cyclohexyl-propyl)-1-lysyl] N-cyclopentylglycine as antihypertensives
US7147538B2 (en) * 2003-06-19 2006-12-12 Hbi Branded Apparel Enterprises, Llc Cushion insert for straps
US9800501B2 (en) 2013-08-28 2017-10-24 Qualcomm Incorporated Methods and apparatus for multiple user uplink

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4105776A (en) * 1976-06-21 1978-08-08 E. R. Squibb & Sons, Inc. Proline derivatives and related compounds
JPS559058A (en) * 1978-07-06 1980-01-22 Dainippon Pharmaceut Co Ltd 1-(3-mercapto-2-methylpropanoyl)prolyl amino acid derivative
IL58849A (en) * 1978-12-11 1983-03-31 Merck & Co Inc Carboxyalkyl dipeptides and derivatives thereof,their preparation and pharmaceutical compositions containing them
EP0018104B1 (en) * 1979-03-26 1983-05-25 Takeda Chemical Industries, Ltd. Tetrahydroisoquinolines, their production and the compounds and pharmaceutical compositions containing them for use in the prevention or treatment of hypertension
US4256761A (en) * 1979-07-13 1981-03-17 Usv Pharmaceutical Corporation Antihypertensive amides
EP0035868A1 (en) * 1980-03-07 1981-09-16 Takeda Chemical Industries, Ltd. Bicyclic compounds, their production and use
FR2480747A1 (fr) * 1980-04-17 1981-10-23 Roques Bernard Derives d'acides amines et leur application therapeutique
EP0054862B1 (en) * 1980-12-18 1985-11-27 Schering Corporation Substituted dipeptides, processes for their preparation and pharmaceutical compositions containing them and their use in the inhibition of enkephalinase
EP0057998B1 (en) * 1981-01-23 1984-08-08 Takeda Chemical Industries, Ltd. Alicyclic compounds, their production and use

Also Published As

Publication number Publication date
EP0092942A2 (en) 1983-11-02
EP0092942B1 (en) 1987-09-09
CA1241644A (en) 1988-09-06
EP0092942A3 (en) 1984-07-11
JPH031319B2 (2) 1991-01-10
US4472383A (en) 1984-09-18
DE3373480D1 (en) 1987-10-15

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