JPS5857407B2 - 直腸投与剤用基剤 - Google Patents

直腸投与剤用基剤

Info

Publication number: JPS5857407B2
Authority: JP; Japan
Prior art keywords: base; acid; salts; salt; rectal administration
Prior art date: 1980-03-19
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

JP55035128A

Other languages

English (en)

Japanese (ja)

Other versions

JPS56131526A (en

Inventor

和彦北尾

憲一西村

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Kyoto Pharmaceutical Industries Ltd

Original Assignee

Kyoto Pharmaceutical Industries Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1980-03-19

Filing date

1980-03-19

Publication date

1983-12-20

1980-03-19 Application filed by Kyoto Pharmaceutical Industries Ltd filed Critical Kyoto Pharmaceutical Industries Ltd

1980-03-19 Priority to JP55035128A priority Critical patent/JPS5857407B2/ja

1980-05-06 Priority to GB8015044A priority patent/GB2051574B/en

1980-05-08 Priority to FR8010267A priority patent/FR2455897A1/fr

1980-05-09 Priority to DE19803017829 priority patent/DE3017829A1/de

1980-05-12 Priority to US06/149,132 priority patent/US4338306A/en

1980-10-24 Priority to AU63686/80A priority patent/AU537260B2/en

1980-10-30 Priority to BE0/202645A priority patent/BE885941A/fr

1980-11-05 Priority to CA000364040A priority patent/CA1166964A/fr

1980-11-06 Priority to CH825580A priority patent/CH645808A5/de

1980-11-06 Priority to SE8007820A priority patent/SE447447B/sv

1980-11-07 Priority to IT25850/80A priority patent/IT1134202B/it

1981-10-15 Publication of JPS56131526A publication Critical patent/JPS56131526A/ja

1982-04-02 Priority to US06/365,021 priority patent/US4485033A/en

1983-12-20 Publication of JPS5857407B2 publication Critical patent/JPS5857407B2/ja

Status Expired legal-status Critical Current

Links

239000002585 base Substances 0.000 claims description 35
150000003839 salts Chemical class 0.000 claims description 24
235000014113 dietary fatty acids Nutrition 0.000 claims description 19
229930195729 fatty acid Natural products 0.000 claims description 19
239000000194 fatty acid Substances 0.000 claims description 19
150000004665 fatty acids Chemical class 0.000 claims description 19
231100000252 nontoxic Toxicity 0.000 claims description 14
230000003000 nontoxic effect Effects 0.000 claims description 14
LVRFTAZAXQPQHI-UHFFFAOYSA-N 2-hydroxy-4-methylvaleric acid Chemical compound CC(C)CC(O)C(O)=O LVRFTAZAXQPQHI-UHFFFAOYSA-N 0.000 claims description 10
125000004432 carbon atom Chemical group C* 0.000 claims description 10
-1 alkali metal salts Chemical class 0.000 claims description 8
229910052783 alkali metal Inorganic materials 0.000 claims description 3
239000013543 active substance Substances 0.000 description 14
GHVNFZFCNZKVNT-UHFFFAOYSA-N decanoic acid Chemical compound CCCCCCCCCC(O)=O GHVNFZFCNZKVNT-UHFFFAOYSA-N 0.000 description 10
NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 description 10
239000008280 blood Substances 0.000 description 9
210000004369 blood Anatomy 0.000 description 9
150000001483 arginine derivatives Chemical class 0.000 description 8
238000000034 method Methods 0.000 description 8
KDXKERNSBIXSRK-YFKPBYRVSA-N L-lysine Chemical class NCCCC[C@H](N)C(O)=O KDXKERNSBIXSRK-YFKPBYRVSA-N 0.000 description 7
POULHZVOKOAJMA-UHFFFAOYSA-N dodecanoic acid Chemical compound CCCCCCCCCCCC(O)=O POULHZVOKOAJMA-UHFFFAOYSA-N 0.000 description 7
239000006215 rectal suppository Substances 0.000 description 7
239000002253 acid Substances 0.000 description 6
WWZKQHOCKIZLMA-UHFFFAOYSA-N octanoic acid Chemical compound CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 description 6
239000005632 Capric acid (CAS 334-48-5) Substances 0.000 description 5
102000004877 Insulin Human genes 0.000 description 5
108090001061 Insulin Proteins 0.000 description 5
238000010521 absorption reaction Methods 0.000 description 5
229940125396 insulin Drugs 0.000 description 5
159000000000 sodium salts Chemical class 0.000 description 5
150000001875 compounds Chemical class 0.000 description 4
229940079593 drug Drugs 0.000 description 4
239000003814 drug Substances 0.000 description 4
239000000203 mixture Substances 0.000 description 4
210000000664 rectum Anatomy 0.000 description 4
239000000829 suppository Substances 0.000 description 4
239000005635 Caprylic acid (CAS 124-07-2) Substances 0.000 description 3
229930186147 Cephalosporin Natural products 0.000 description 3
239000005639 Lauric acid Substances 0.000 description 3
229930182555 Penicillin Natural products 0.000 description 3
239000003242 anti bacterial agent Substances 0.000 description 3
229940088710 antibiotic agent Drugs 0.000 description 3
239000003782 beta lactam antibiotic agent Substances 0.000 description 3
229940124587 cephalosporin Drugs 0.000 description 3
150000001780 cephalosporins Chemical class 0.000 description 3
229960002446 octanoic acid Drugs 0.000 description 3
XAEFZNCEHLXOMS-UHFFFAOYSA-M potassium benzoate Chemical compound [K+].[O-]C(=O)C1=CC=CC=C1 XAEFZNCEHLXOMS-UHFFFAOYSA-M 0.000 description 3
108090000765 processed proteins & peptides Proteins 0.000 description 3
229940100618 rectal suppository Drugs 0.000 description 3
210000002700 urine Anatomy 0.000 description 3
239000002132 β-lactam antibiotic Substances 0.000 description 3
229940124586 β-lactam antibiotics Drugs 0.000 description 3
241000894006 Bacteria Species 0.000 description 2
PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 2
KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 description 2
239000004472 Lysine Substances 0.000 description 2
QQONPFPTGQHPMA-UHFFFAOYSA-N Propene Chemical compound CC=C QQONPFPTGQHPMA-UHFFFAOYSA-N 0.000 description 2
150000007513 acids Chemical class 0.000 description 2
210000000436 anus Anatomy 0.000 description 2
230000007423 decrease Effects 0.000 description 2
239000002552 dosage form Substances 0.000 description 2
238000009472 formulation Methods 0.000 description 2
238000002347 injection Methods 0.000 description 2
239000007924 injection Substances 0.000 description 2
238000000691 measurement method Methods 0.000 description 2
FBUKVWPVBMHYJY-UHFFFAOYSA-N nonanoic acid Chemical compound CCCCCCCCC(O)=O FBUKVWPVBMHYJY-UHFFFAOYSA-N 0.000 description 2
150000007523 nucleic acids Chemical class 0.000 description 2
102000039446 nucleic acids Human genes 0.000 description 2
108020004707 nucleic acids Proteins 0.000 description 2
150000002960 penicillins Chemical class 0.000 description 2
238000002360 preparation method Methods 0.000 description 2
102000004196 processed proteins & peptides Human genes 0.000 description 2
239000011734 sodium Substances 0.000 description 2
ZDPHROOEEOARMN-UHFFFAOYSA-N undecanoic acid Chemical compound CCCCCCCCCCC(O)=O ZDPHROOEEOARMN-UHFFFAOYSA-N 0.000 description 2
LVRFTAZAXQPQHI-RXMQYKEDSA-N (R)-2-hydroxy-4-methylpentanoic acid Chemical compound CC(C)C[C@@H](O)C(O)=O LVRFTAZAXQPQHI-RXMQYKEDSA-N 0.000 description 1
244000063299 Bacillus subtilis Species 0.000 description 1
235000014469 Bacillus subtilis Nutrition 0.000 description 1
WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
108010015776 Glucose oxidase Proteins 0.000 description 1
239000004366 Glucose oxidase Substances 0.000 description 1
DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
241000191938 Micrococcus luteus Species 0.000 description 1
206010062575 Muscle contracture Diseases 0.000 description 1
241000283973 Oryctolagus cuniculus Species 0.000 description 1
235000019483 Peanut oil Nutrition 0.000 description 1
239000005643 Pelargonic acid Substances 0.000 description 1
JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 description 1
239000004264 Petrolatum Substances 0.000 description 1
239000002202 Polyethylene glycol Substances 0.000 description 1
ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
244000299461 Theobroma cacao Species 0.000 description 1
235000005764 Theobroma cacao ssp. cacao Nutrition 0.000 description 1
235000005767 Theobroma cacao ssp. sphaerocarpum Nutrition 0.000 description 1
239000000654 additive Substances 0.000 description 1
150000001340 alkali metals Chemical class 0.000 description 1
KLOHDWPABZXLGI-YWUHCJSESA-M ampicillin sodium Chemical compound [Na+].C1([C@@H](N)C(=O)N[C@H]2[C@H]3SC([C@@H](N3C2=O)C([O-])=O)(C)C)=CC=CC=C1 KLOHDWPABZXLGI-YWUHCJSESA-M 0.000 description 1
229960001931 ampicillin sodium Drugs 0.000 description 1
239000003963 antioxidant agent Substances 0.000 description 1
230000003078 antioxidant effect Effects 0.000 description 1
238000004166 bioassay Methods 0.000 description 1
230000003115 biocidal effect Effects 0.000 description 1
235000014121 butter Nutrition 0.000 description 1
235000001046 cacaotero Nutrition 0.000 description 1
150000001735 carboxylic acids Chemical class 0.000 description 1
239000004359 castor oil Substances 0.000 description 1
235000019438 castor oil Nutrition 0.000 description 1
208000006111 contracture Diseases 0.000 description 1
238000007796 conventional method Methods 0.000 description 1
235000005687 corn oil Nutrition 0.000 description 1
239000002285 corn oil Substances 0.000 description 1
238000007821 culture assay Methods 0.000 description 1
230000003247 decreasing effect Effects 0.000 description 1
102000038379 digestive enzymes Human genes 0.000 description 1
108091007734 digestive enzymes Proteins 0.000 description 1
239000003925 fat Substances 0.000 description 1
210000001035 gastrointestinal tract Anatomy 0.000 description 1
238000007429 general method Methods 0.000 description 1
239000008103 glucose Substances 0.000 description 1
229940116332 glucose oxidase Drugs 0.000 description 1
235000019420 glucose oxidase Nutrition 0.000 description 1
235000011187 glycerol Nutrition 0.000 description 1
ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 description 1
150000002314 glycerols Chemical class 0.000 description 1
230000007062 hydrolysis Effects 0.000 description 1
238000006460 hydrolysis reaction Methods 0.000 description 1
239000012535 impurity Substances 0.000 description 1
230000000968 intestinal effect Effects 0.000 description 1
210000000936 intestine Anatomy 0.000 description 1
210000004731 jugular vein Anatomy 0.000 description 1
239000007788 liquid Substances 0.000 description 1
238000004519 manufacturing process Methods 0.000 description 1
239000002480 mineral oil Substances 0.000 description 1
238000002156 mixing Methods 0.000 description 1
230000003387 muscular Effects 0.000 description 1
VQVWOSSLNTVNTB-UHFFFAOYSA-J octanoate thorium(4+) Chemical compound [Th+4].CCCCCCCC([O-])=O.CCCCCCCC([O-])=O.CCCCCCCC([O-])=O.CCCCCCCC([O-])=O VQVWOSSLNTVNTB-UHFFFAOYSA-J 0.000 description 1
239000003921 oil Substances 0.000 description 1
235000019198 oils Nutrition 0.000 description 1
235000014593 oils and fats Nutrition 0.000 description 1
239000002674 ointment Substances 0.000 description 1
239000004006 olive oil Substances 0.000 description 1
235000008390 olive oil Nutrition 0.000 description 1
150000007530 organic bases Chemical class 0.000 description 1
239000012188 paraffin wax Substances 0.000 description 1
239000002245 particle Substances 0.000 description 1
239000000312 peanut oil Substances 0.000 description 1
229940049954 penicillin Drugs 0.000 description 1
229940066842 petrolatum Drugs 0.000 description 1
235000019271 petrolatum Nutrition 0.000 description 1
239000008194 pharmaceutical composition Substances 0.000 description 1
230000036470 plasma concentration Effects 0.000 description 1
229920001223 polyethylene glycol Polymers 0.000 description 1
229920000642 polymer Polymers 0.000 description 1
229910052700 potassium Inorganic materials 0.000 description 1
239000011591 potassium Substances 0.000 description 1
159000000001 potassium salts Chemical class 0.000 description 1
239000003755 preservative agent Substances 0.000 description 1
230000001737 promoting effect Effects 0.000 description 1
238000011160 research Methods 0.000 description 1
229910052708 sodium Inorganic materials 0.000 description 1
239000007901 soft capsule Substances 0.000 description 1
239000007787 solid Substances 0.000 description 1
239000004094 surface-active agent Substances 0.000 description 1
239000000725 suspension Substances 0.000 description 1
238000012360 testing method Methods 0.000 description 1
TUNFSRHWOTWDNC-HKGQFRNVSA-N tetradecanoic acid Chemical compound CCCCCCCCCCCCC[14C](O)=O TUNFSRHWOTWDNC-HKGQFRNVSA-N 0.000 description 1
230000036325 urinary excretion Effects 0.000 description 1
235000015112 vegetable and seed oil Nutrition 0.000 description 1
235000019871 vegetable fat Nutrition 0.000 description 1
239000008158 vegetable oil Substances 0.000 description 1
210000003462 vein Anatomy 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/02—Suppositories; Bougies; Bases therefor; Ovules

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Oil, Petroleum & Natural Gas (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

JP55035128A 1979-05-10 1980-03-19 直腸投与剤用基剤 Expired JPS5857407B2 (ja)

Priority Applications (12)

Application Number	Priority Date	Filing Date	Title
JP55035128A JPS5857407B2 (ja)	1980-03-19	1980-03-19	直腸投与剤用基剤
GB8015044A GB2051574B (en)	1979-05-10	1980-05-06	Adjuvant for promoting absorption of pharmacologically active substances through the rectum
FR8010267A FR2455897A1 (fr)	1979-05-10	1980-05-08	Adjuvant du type acide gras pour favoriser l'absorption de substances pharmacologiquement actives par le rectum, composition de base pour administration rectale comprenant cet adjuvant et composition pharmaceutique comprenant cet adjuvant
DE19803017829 DE3017829A1 (de)	1979-05-10	1980-05-09	Adjuvans zur foerderung der rektalen absorption von pharmazeutischen wirkstoffen und dieses adjuvans enthaltende mittel
US06/149,132 US4338306A (en)	1979-05-10	1980-05-12	Adjuvant for promoting absorption of pharmacologically active substances through the rectum
AU63686/80A AU537260B2 (en)	1980-03-19	1980-10-24	Rectal base composition
BE0/202645A BE885941A (fr)	1980-03-19	1980-10-30	Adjuvant favorisant l'absorption de substances pharmacologiques par le rectum, et composition de base et composition pharmaceutique comprenant cet adjuvant
CA000364040A CA1166964A (fr)	1979-05-10	1980-11-05	Adjuvant pour favoriser l'absorption de substances a action pharmacologique administrees par voie rectale, composes pharmaceutiques et base excipiente contenant cet adjuvant
CH825580A CH645808A5 (en)	1980-03-19	1980-11-06	Adjuvant for promoting rectal absorption of pharmaceutical agents and compositions containing this adjuvant
SE8007820A SE447447B (sv)	1980-03-19	1980-11-06	Adjuvanskomposition for att befremja absorption av farmakologiskt aktiva substanser fran rektum innehallande icke-toxiska salt av fettsyror med 8-12 kolatomer och icke-toxiska salt av leucinsyra
IT25850/80A IT1134202B (it)	1980-03-19	1980-11-07	Coadiuvante per promuovere l'absorbimento di sostanze farmacologicamente attive attraverso il retto,e composizione farmaceutica che lo comprendono
US06/365,021 US4485033A (en)	1979-05-10	1982-04-02	Adjuvant for promoting absorption of pharmacologically active substances through the rectum

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP55035128A JPS5857407B2 (ja)	1980-03-19	1980-03-19	直腸投与剤用基剤

Publications (2)

Publication Number	Publication Date
JPS56131526A JPS56131526A (en)	1981-10-15
JPS5857407B2 true JPS5857407B2 (ja)	1983-12-20

Family

ID=12433287

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP55035128A Expired JPS5857407B2 (ja)	1979-05-10	1980-03-19	直腸投与剤用基剤

Country Status (6)

Country	Link
JP (1)	JPS5857407B2 (fr)
AU (1)	AU537260B2 (fr)
BE (1)	BE885941A (fr)
CH (1)	CH645808A5 (fr)
IT (1)	IT1134202B (fr)
SE (1)	SE447447B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US11000636B2 (en)	2016-09-30	2021-05-11	Toray Industries, Inc.	Copolymer and medical material containing the same

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE4134831C2 (de) *	1991-10-22	1995-05-18	Mannesmann Ag	Anordnung zur Ermittlung einer Reibbeiwert-Information
US6794357B1 (en)	1993-06-24	2004-09-21	Astrazeneca Ab	Compositions for inhalation
US5830853A (en)	1994-06-23	1998-11-03	Astra Aktiebolag	Systemic administration of a therapeutic preparation
ITMI20070084A1 (it) *	2007-01-22	2008-07-23	Carlo Ghisalberti	Dispositivi antisettici vaginali a base lipidica

1980
- 1980-03-19 JP JP55035128A patent/JPS5857407B2/ja not_active Expired
- 1980-10-24 AU AU63686/80A patent/AU537260B2/en not_active Expired
- 1980-10-30 BE BE0/202645A patent/BE885941A/fr not_active IP Right Cessation
- 1980-11-06 SE SE8007820A patent/SE447447B/sv not_active IP Right Cessation
- 1980-11-06 CH CH825580A patent/CH645808A5/de not_active IP Right Cessation
- 1980-11-07 IT IT25850/80A patent/IT1134202B/it active

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US11000636B2 (en)	2016-09-30	2021-05-11	Toray Industries, Inc.	Copolymer and medical material containing the same
EP3845573A1 (fr)	2016-09-30	2021-07-07	Toray Industries, Inc.	Copolymère et matériel médical le contenant

Also Published As

Publication number	Publication date
BE885941A (fr)	1981-02-16
CH645808A5 (en)	1984-10-31
SE447447B (sv)	1986-11-17
AU6368680A (en)	1981-09-24
SE8007820L (sv)	1981-09-20
JPS56131526A (en)	1981-10-15
IT1134202B (it)	1986-08-13
IT8025850A0 (it)	1980-11-07
AU537260B2 (en)	1984-06-14

Publication	Publication Date	Title
US4485033A (en)	1984-11-27	Adjuvant for promoting absorption of pharmacologically active substances through the rectum
US4442090A (en)	1984-04-10	Absorption-promoting compounds, compositions thereof with pharmaceuticals and/or bases for rectal administration and method of use
JPWO1993008804A1 (ja)	1993-11-04	プロスタグランジン化合物含有直腸または膣投与用製剤
UA72541C2 (en)	2005-03-15	A pharmaceutical composition containing benzamide derivative
AU625276B2 (en)	1992-07-09	Pharmaceutical compositions
JP4584715B2 (ja)	2010-11-24	持続放出性医薬組成物
CA2123007A1 (fr)	1993-05-13	Preparation pharmaceutique contenant un compose de la prostaglandine, pour administration rectale ou vaginale
JPS5857407B2 (ja)	1983-12-20	直腸投与剤用基剤
AU2002348256B2 (en)	2005-09-01	Antibiotic formulation and a method of making this formulation
CA1334934C (fr)	1995-03-28	Composition antibacterienne administree par voie orale
JPS6396138A (ja)	1988-04-27	製薬学的組成物
JPS6256128B2 (fr)	1987-11-24
JPS6346727B2 (fr)	1988-09-19
JPS60149519A (ja)	1985-08-07	直腸投与用組成物
JPS6055486B2 (ja)	1985-12-05	β−ラクタム環を有する化合物の直腸投与用組成物
JPS6235A (ja)	1987-01-06	カルシトニン類の直腸投与用組成物
RU2777360C1 (ru)	2022-08-02	Готовые к применению лекарственные формы для инъекций
RU2777360C9 (ru)	2022-09-14	Готовые к применению лекарственные формы для инъекций
JPS6067413A (ja)	1985-04-17	直腸投与用組成物
JP7323630B2 (ja)	2023-08-08	使用準備が整った注射用製剤
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