JPS5888316A - 傷治癒用組成物、その製法及び利用 - Google Patents
傷治癒用組成物、その製法及び利用Info
- Publication number
- JPS5888316A JPS5888316A JP57192628A JP19262882A JPS5888316A JP S5888316 A JPS5888316 A JP S5888316A JP 57192628 A JP57192628 A JP 57192628A JP 19262882 A JP19262882 A JP 19262882A JP S5888316 A JPS5888316 A JP S5888316A
- Authority
- JP
- Japan
- Prior art keywords
- medium
- ointment
- amniotic membrane
- preparation
- preparation according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 title claims description 19
- 238000004519 manufacturing process Methods 0.000 title claims description 10
- 210000001691 amnion Anatomy 0.000 claims description 36
- 239000002609 medium Substances 0.000 claims description 25
- 206010052428 Wound Diseases 0.000 claims description 21
- 208000027418 Wounds and injury Diseases 0.000 claims description 20
- 239000002674 ointment Substances 0.000 claims description 20
- 238000002360 preparation method Methods 0.000 claims description 18
- 239000001963 growth medium Substances 0.000 claims description 16
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 claims description 6
- 239000007788 liquid Substances 0.000 claims description 4
- 239000004480 active ingredient Substances 0.000 claims description 3
- 229910002092 carbon dioxide Inorganic materials 0.000 claims description 3
- 239000001569 carbon dioxide Substances 0.000 claims description 3
- 238000012258 culturing Methods 0.000 claims description 3
- 239000012188 paraffin wax Substances 0.000 claims description 3
- 230000001804 emulsifying effect Effects 0.000 claims description 2
- 238000001914 filtration Methods 0.000 claims description 2
- 239000003899 bactericide agent Substances 0.000 claims 2
- 230000000474 nursing effect Effects 0.000 claims 2
- 206010011224 Cough Diseases 0.000 claims 1
- 235000016623 Fragaria vesca Nutrition 0.000 claims 1
- 240000009088 Fragaria x ananassa Species 0.000 claims 1
- 235000011363 Fragaria x ananassa Nutrition 0.000 claims 1
- 241001494479 Pecora Species 0.000 claims 1
- 101150063503 RAI1 gene Proteins 0.000 claims 1
- 101100224844 Schizosaccharomyces pombe (strain 972 / ATCC 24843) din1 gene Proteins 0.000 claims 1
- 241000270708 Testudinidae Species 0.000 claims 1
- 239000007864 aqueous solution Substances 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 238000004587 chromatography analysis Methods 0.000 claims 1
- 238000009472 formulation Methods 0.000 claims 1
- 239000008311 hydrophilic ointment Substances 0.000 claims 1
- 238000000746 purification Methods 0.000 claims 1
- 210000004027 cell Anatomy 0.000 description 9
- 238000000034 method Methods 0.000 description 7
- 230000029663 wound healing Effects 0.000 description 6
- 239000000853 adhesive Substances 0.000 description 5
- 230000001070 adhesive effect Effects 0.000 description 5
- 239000010410 layer Substances 0.000 description 5
- 150000003839 salts Chemical class 0.000 description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 5
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 4
- 208000025865 Ulcer Diseases 0.000 description 4
- 230000002745 absorbent Effects 0.000 description 4
- 239000002250 absorbent Substances 0.000 description 4
- 230000001737 promoting effect Effects 0.000 description 4
- 231100000397 ulcer Toxicity 0.000 description 4
- 239000002870 angiogenesis inducing agent Substances 0.000 description 3
- 230000002491 angiogenic effect Effects 0.000 description 3
- 210000001136 chorion Anatomy 0.000 description 3
- 210000004379 membrane Anatomy 0.000 description 3
- 239000012528 membrane Substances 0.000 description 3
- 239000000843 powder Substances 0.000 description 3
- 210000001519 tissue Anatomy 0.000 description 3
- 239000003104 tissue culture media Substances 0.000 description 3
- 208000008601 Polycythemia Diseases 0.000 description 2
- 241001474791 Proboscis Species 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- 239000002390 adhesive tape Substances 0.000 description 2
- 239000012298 atmosphere Substances 0.000 description 2
- 230000001684 chronic effect Effects 0.000 description 2
- 239000006071 cream Substances 0.000 description 2
- 239000000645 desinfectant Substances 0.000 description 2
- 239000012153 distilled water Substances 0.000 description 2
- 239000000284 extract Substances 0.000 description 2
- 239000011521 glass Substances 0.000 description 2
- 230000035876 healing Effects 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 210000002966 serum Anatomy 0.000 description 2
- 235000017557 sodium bicarbonate Nutrition 0.000 description 2
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 2
- 238000003860 storage Methods 0.000 description 2
- UCSJYZPVAKXKNQ-HZYVHMACSA-N streptomycin Chemical compound CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@@H]1[C@](C=O)(O)[C@H](C)O[C@H]1O[C@@H]1[C@@H](NC(N)=N)[C@H](O)[C@@H](NC(N)=N)[C@H](O)[C@H]1O UCSJYZPVAKXKNQ-HZYVHMACSA-N 0.000 description 2
- JKMHFZQWWAIEOD-UHFFFAOYSA-N 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonic acid Chemical compound OCC[NH+]1CCN(CCS([O-])(=O)=O)CC1 JKMHFZQWWAIEOD-UHFFFAOYSA-N 0.000 description 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- 206010063560 Excessive granulation tissue Diseases 0.000 description 1
- 108010010803 Gelatin Proteins 0.000 description 1
- 239000007995 HEPES buffer Substances 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- 208000037581 Persistent Infection Diseases 0.000 description 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 1
- 208000007536 Thrombosis Diseases 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
- 239000012790 adhesive layer Substances 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 230000033115 angiogenesis Effects 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 230000002421 anti-septic effect Effects 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 230000036770 blood supply Effects 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 229910052792 caesium Inorganic materials 0.000 description 1
- TVFDJXOCXUVLDH-UHFFFAOYSA-N caesium atom Chemical compound [Cs] TVFDJXOCXUVLDH-UHFFFAOYSA-N 0.000 description 1
- 244000309466 calf Species 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 235000014633 carbohydrates Nutrition 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 239000000969 carrier Substances 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 230000001055 chewing effect Effects 0.000 description 1
- 230000035606 childbirth Effects 0.000 description 1
- 239000000356 contaminant Substances 0.000 description 1
- 238000002316 cosmetic surgery Methods 0.000 description 1
- 210000003785 decidua Anatomy 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 230000001605 fetal effect Effects 0.000 description 1
- 210000002950 fibroblast Anatomy 0.000 description 1
- 210000003953 foreskin Anatomy 0.000 description 1
- 238000004108 freeze drying Methods 0.000 description 1
- FBPFZTCFMRRESA-GUCUJZIJSA-N galactitol Chemical compound OC[C@H](O)[C@@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-GUCUJZIJSA-N 0.000 description 1
- 229920000159 gelatin Polymers 0.000 description 1
- 239000008273 gelatin Substances 0.000 description 1
- 235000019322 gelatine Nutrition 0.000 description 1
- 235000011852 gelatine desserts Nutrition 0.000 description 1
- 210000001126 granulation tissue Anatomy 0.000 description 1
- 238000003306 harvesting Methods 0.000 description 1
- 210000003128 head Anatomy 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 210000005260 human cell Anatomy 0.000 description 1
- 239000012678 infectious agent Substances 0.000 description 1
- 230000036512 infertility Effects 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 230000009545 invasion Effects 0.000 description 1
- 210000003127 knee Anatomy 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 235000010755 mineral Nutrition 0.000 description 1
- 239000011707 mineral Chemical class 0.000 description 1
- 239000002808 molecular sieve Substances 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 230000032696 parturition Effects 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- -1 phospho Chemical class 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 210000004894 snout Anatomy 0.000 description 1
- URGAHOPLAPQHLN-UHFFFAOYSA-N sodium aluminosilicate Chemical compound [Na+].[Al+3].[O-][Si]([O-])=O.[O-][Si]([O-])=O URGAHOPLAPQHLN-UHFFFAOYSA-N 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 210000004872 soft tissue Anatomy 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 229960005322 streptomycin Drugs 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- 238000013268 sustained release Methods 0.000 description 1
- 239000012730 sustained-release form Substances 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/50—Placenta; Placental stem cells; Amniotic fluid; Amnion; Amniotic stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Developmental Biology & Embryology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- General Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pregnancy & Childbirth (AREA)
- Reproductive Health (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Virology (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Materials For Medical Uses (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8133375 | 1981-11-05 | ||
| GB08133375A GB2110531B (en) | 1981-11-05 | 1981-11-05 | Wound healing composition prepared from amnion |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS5888316A true JPS5888316A (ja) | 1983-05-26 |
Family
ID=10525651
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP57192628A Pending JPS5888316A (ja) | 1981-11-05 | 1982-11-04 | 傷治癒用組成物、その製法及び利用 |
Country Status (7)
| Country | Link |
|---|---|
| JP (1) | JPS5888316A (de) |
| AT (1) | ATA402782A (de) |
| AU (1) | AU9010382A (de) |
| DE (1) | DE3240909A1 (de) |
| GB (1) | GB2110531B (de) |
| NZ (1) | NZ202259A (de) |
| ZA (1) | ZA828111B (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8708009D0 (en) * | 1987-04-03 | 1987-05-07 | Clayton Found Res | Injectable soft tissue augmentation materials |
| GB8803697D0 (en) * | 1988-02-17 | 1988-03-16 | Deltanine Research Ltd | Clinical developments using amniotic membrane cells |
| WO1991000098A1 (fr) * | 1989-06-23 | 1991-01-10 | Kishinevsky Selskokhozyaistvenny Institut Imeni M.V.Frunze | Preparation anti-inflammatoire et son procede d'obtention |
| EP0735135A3 (de) * | 1995-03-31 | 1997-12-29 | DIZG Deutsches Institüt für Zell- und Gewebeersatz gGmbH | Zellschichten und Transportsystem für Zellschichten |
| RU2156131C1 (ru) * | 1996-06-21 | 2000-09-20 | Беляев Юрий Евгеньевич | Полуфабрикат для получения основы лекарственного средства, основы лекарственного средства из этого полуфабриката (варианты) и лекарственное средство на этой основе (варианты) |
| DE19925549B4 (de) * | 1999-06-04 | 2004-12-23 | Lts Lohmann Therapie-Systeme Ag | Verfahren zur aseptischen Herstellung von Wundauflagen und Verwendung derselben |
| EP1549328A4 (de) * | 2002-09-18 | 2009-07-08 | Emiliano Ghinelli | Verwendung einer humanen schafhäutchen-zusammesentzung zur prophylaxe und behandlung von erkrankungen und zuständen des auges und der haut |
| WO2004033635A2 (en) * | 2002-10-04 | 2004-04-22 | Tissuetech, Inc. | Retinal pigment epithelial cell cultures on amniotic membrane and transplantation |
| CN103361301A (zh) * | 2005-03-31 | 2013-10-23 | 斯丹姆涅恩有限公司 | 高度纯化来自羊膜的细胞群 |
| GB0514567D0 (en) * | 2005-07-15 | 2005-08-24 | Univ Nottingham | Surgical membrane |
| US8871198B2 (en) * | 2006-03-29 | 2014-10-28 | Stemnion, Inc. | Methods related to wound healing |
| US20090004161A1 (en) | 2007-06-26 | 2009-01-01 | Palladino Linda O | Methods for treating pustular conditions of the skin |
| US20120121547A1 (en) * | 2010-09-16 | 2012-05-17 | Wagner Donald J | Methods and compositions for treating chronic wounds |
-
1981
- 1981-11-05 GB GB08133375A patent/GB2110531B/en not_active Expired
-
1982
- 1982-10-21 NZ NZ202259A patent/NZ202259A/en unknown
- 1982-11-03 AU AU90103/82A patent/AU9010382A/en not_active Abandoned
- 1982-11-04 JP JP57192628A patent/JPS5888316A/ja active Pending
- 1982-11-04 ZA ZA828111A patent/ZA828111B/xx unknown
- 1982-11-04 AT AT0402782A patent/ATA402782A/de not_active IP Right Cessation
- 1982-11-05 DE DE19823240909 patent/DE3240909A1/de not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| AU9010382A (en) | 1983-05-12 |
| GB2110531B (en) | 1985-05-01 |
| NZ202259A (en) | 1985-07-31 |
| ZA828111B (en) | 1984-06-27 |
| ATA402782A (de) | 1985-06-15 |
| DE3240909A1 (de) | 1983-05-11 |
| GB2110531A (en) | 1983-06-22 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US4570629A (en) | Hydrophilic biopolymeric copolyelectrolytes, and biodegradable wound dressing comprising same | |
| CA2351341C (en) | Collagen hemostatic foam | |
| US4414202A (en) | Composition for treatment of wounds | |
| US7196054B1 (en) | Methods for treating wound tissue and forming a supplemented fibrin matrix | |
| US4778679A (en) | Method and composition for treatment of wounds | |
| JPH0636815B2 (ja) | 人工皮膜代用品としてのセルロース皮膜の製造方法 | |
| JPS5888316A (ja) | 傷治癒用組成物、その製法及び利用 | |
| CN109731130A (zh) | 一种低温生物3d打印技术制备水凝胶创面敷料的方法 | |
| JPH0549302B2 (de) | ||
| KR20010042539A (ko) | 액체매체 속의 천연 콜라겐의 멸균 방법, 획득된 멸균천연 콜라겐, 그 것을 함유하는 조성물 및 용도 | |
| JP2002501525A (ja) | 火傷及び他の皮膚外傷の治療のための組成物及び手段 | |
| US5300306A (en) | Tissue-equivalent membrane from bovine esophageal tissue | |
| Gupta et al. | Calcium alginate in the management of acute surgical wounds and abscesses | |
| CZ277766B6 (en) | Biologically active material and process for preparing thereof | |
| CN108350420A (zh) | 培养细胞的方法 | |
| EP0034504B1 (de) | Kombinationen für die Behandlung von Wunden | |
| CN103083721B (zh) | 一种京尼平固定活化素b的人工皮肤移植物及制备方法 | |
| GB2146523A (en) | Preparation for stimulating growth of blood vessels prepared from aminochorionic tissue and macrophages | |
| CZ305405B6 (cs) | Použití kombinace obsahující polymerové absorpční činidlo a nemetabolizovatelný cukr pro podporu buněčné rekonstrukce a/nebo buněčné diferenciace | |
| Degernes et al. | Soft-tissue wound management in avian patients | |
| Ferguson et al. | Preparation of cell cultures from human amnion | |
| RU2158112C1 (ru) | Способ кожной пластики | |
| RU2841638C1 (ru) | Способ лечения инфицированных ран у крупного рогатого скота | |
| JPH0720873B2 (ja) | 創傷治癒剤 | |
| JPH0966097A (ja) | 皮膚欠損治療用被覆材 |