JPS60222412A - 水性液剤不溶成分の分離法 - Google Patents

水性液剤不溶成分の分離法

Info

Publication number: JPS60222412A
Authority: JP; Japan
Prior art keywords: crude drug; components; aqueous solution; resultant mixture; castor oil
Prior art date: 1984-04-09
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

JP59071187A

Other languages

English (en)

Japanese (ja)

Other versions

JPS625888B2 (de

Inventor

Seiji Sekino

関野　清治

Kenji Kawasuji

川筋　健次

Jiro Sekiya

関谷　二郎

Kiichi Kubo

喜一久保

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

KOUKANDOU KK

Original Assignee

KOUKANDOU KK

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-04-09

Filing date

1984-04-09

Publication date

1985-11-07

1984-04-09 Application filed by KOUKANDOU KK filed Critical KOUKANDOU KK

1984-04-09 Priority to JP59071187A priority Critical patent/JPS60222412A/ja

1985-11-07 Publication of JPS60222412A publication Critical patent/JPS60222412A/ja

1987-02-07 Publication of JPS625888B2 publication Critical patent/JPS625888B2/ja

Status Granted legal-status Critical Current

Links

239000007864 aqueous solution Substances 0.000 title claims abstract description 10
238000000034 method Methods 0.000 title claims description 9
229940079593 drug Drugs 0.000 claims abstract description 28
239000003814 drug Substances 0.000 claims abstract description 28
239000000243 solution Substances 0.000 claims abstract description 16
229920003171 Poly (ethylene oxide) Polymers 0.000 claims abstract description 12
-1 polyoxyethylene Polymers 0.000 claims abstract description 12
239000001267 polyvinylpyrrolidone Substances 0.000 claims abstract description 11
229920000036 polyvinylpyrrolidone Polymers 0.000 claims abstract description 11
235000013855 polyvinylpyrrolidone Nutrition 0.000 claims abstract description 11
239000004359 castor oil Substances 0.000 claims abstract description 10
235000019438 castor oil Nutrition 0.000 claims abstract description 10
ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 claims abstract description 10
238000004519 manufacturing process Methods 0.000 claims description 8
238000001802 infusion Methods 0.000 claims description 4
238000010438 heat treatment Methods 0.000 abstract description 4
239000002244 precipitate Substances 0.000 abstract description 4
IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 abstract description 2
229920000642 polymer Polymers 0.000 abstract description 2
239000011369 resultant mixture Substances 0.000 abstract 3
230000001376 precipitating effect Effects 0.000 abstract 2
238000000151 deposition Methods 0.000 abstract 1
230000003311 flocculating effect Effects 0.000 abstract 1
238000004321 preservation Methods 0.000 abstract 1
239000000306 component Substances 0.000 description 24
239000007788 liquid Substances 0.000 description 18
241000411851 herbal medicine Species 0.000 description 16
239000000284 extract Substances 0.000 description 14
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 12
238000002360 preparation method Methods 0.000 description 11
238000001556 precipitation Methods 0.000 description 9
239000004615 ingredient Substances 0.000 description 7
239000000203 mixture Substances 0.000 description 7
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 7
241000893536 Epimedium Species 0.000 description 6
235000018905 epimedium Nutrition 0.000 description 6
239000008213 purified water Substances 0.000 description 6
241001632410 Eleutherococcus senticosus Species 0.000 description 5
238000001816 cooling Methods 0.000 description 4
230000000694 effects Effects 0.000 description 4
238000001914 filtration Methods 0.000 description 4
239000003795 chemical substances by application Substances 0.000 description 3
KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
239000000706 filtrate Substances 0.000 description 3
238000009472 formulation Methods 0.000 description 3
238000002386 leaching Methods 0.000 description 3
235000020733 paullinia cupana extract Nutrition 0.000 description 3
DFPAKSUCGFBDDF-UHFFFAOYSA-N Nicotinamide Chemical compound NC(=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-UHFFFAOYSA-N 0.000 description 2
235000000556 Paullinia cupana Nutrition 0.000 description 2
240000003444 Paullinia cupana Species 0.000 description 2
239000012141 concentrate Substances 0.000 description 2
235000008504 concentrate Nutrition 0.000 description 2
FVTCRASFADXXNN-SCRDCRAPSA-N flavin mononucleotide Chemical compound OP(=O)(O)OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O FVTCRASFADXXNN-SCRDCRAPSA-N 0.000 description 2
239000003978 infusion fluid Substances 0.000 description 2
229940100688 oral solution Drugs 0.000 description 2
239000003755 preservative agent Substances 0.000 description 2
238000012545 processing Methods 0.000 description 2
239000000047 product Substances 0.000 description 2
229950001574 riboflavin phosphate Drugs 0.000 description 2
239000000126 substance Substances 0.000 description 2
230000001256 tonic effect Effects 0.000 description 2
229940088594 vitamin Drugs 0.000 description 2
239000011782 vitamin Substances 0.000 description 2
235000013343 vitamin Nutrition 0.000 description 2
229930003231 vitamin Natural products 0.000 description 2
206010063659 Aversion Diseases 0.000 description 1
FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 1
235000004443 Ricinus communis Nutrition 0.000 description 1
229930006000 Sucrose Natural products 0.000 description 1
CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
239000004480 active ingredient Substances 0.000 description 1
238000004220 aggregation Methods 0.000 description 1
230000002776 aggregation Effects 0.000 description 1
ZOJBYZNEUISWFT-UHFFFAOYSA-N allyl isothiocyanate Chemical class C=CCN=C=S ZOJBYZNEUISWFT-UHFFFAOYSA-N 0.000 description 1
239000008122 artificial sweetener Substances 0.000 description 1
235000021311 artificial sweeteners Nutrition 0.000 description 1
230000009286 beneficial effect Effects 0.000 description 1
229960001948 caffeine Drugs 0.000 description 1
RYYVLZVUVIJVGH-UHFFFAOYSA-N caffeine Chemical compound CN1C(=O)N(C)C(=O)C2=C1N=CN2C RYYVLZVUVIJVGH-UHFFFAOYSA-N 0.000 description 1
FAPWYRCQGJNNSJ-UBKPKTQASA-L calcium D-pantothenic acid Chemical compound [Ca+2].OCC(C)(C)[C@@H](O)C(=O)NCCC([O-])=O.OCC(C)(C)[C@@H](O)C(=O)NCCC([O-])=O FAPWYRCQGJNNSJ-UBKPKTQASA-L 0.000 description 1
229960002079 calcium pantothenate Drugs 0.000 description 1
238000006243 chemical reaction Methods 0.000 description 1
238000011161 development Methods 0.000 description 1
230000035622 drinking Effects 0.000 description 1
238000000605 extraction Methods 0.000 description 1
210000000416 exudates and transudate Anatomy 0.000 description 1
235000003599 food sweetener Nutrition 0.000 description 1
239000000321 herbal drug Substances 0.000 description 1
238000009776 industrial production Methods 0.000 description 1
230000007774 longterm Effects 0.000 description 1
239000000463 material Substances 0.000 description 1
229940126601 medicinal product Drugs 0.000 description 1
229960003966 nicotinamide Drugs 0.000 description 1
235000005152 nicotinamide Nutrition 0.000 description 1
239000011570 nicotinamide Substances 0.000 description 1
239000002304 perfume Substances 0.000 description 1
239000005426 pharmaceutical component Substances 0.000 description 1
238000006116 polymerization reaction Methods 0.000 description 1
239000011148 porous material Substances 0.000 description 1
229940089808 pyridoxine hydrochloride 10 mg Drugs 0.000 description 1
238000011160 research Methods 0.000 description 1
238000000926 separation method Methods 0.000 description 1
239000001509 sodium citrate Substances 0.000 description 1
NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 1
230000003381 solubilizing effect Effects 0.000 description 1
239000000600 sorbitol Substances 0.000 description 1
230000002269 spontaneous effect Effects 0.000 description 1
238000003860 storage Methods 0.000 description 1
235000000346 sugar Nutrition 0.000 description 1
150000008163 sugars Chemical class 0.000 description 1
239000003765 sweetening agent Substances 0.000 description 1
235000020357 syrup Nutrition 0.000 description 1
239000006188 syrup Substances 0.000 description 1
238000012360 testing method Methods 0.000 description 1
239000002562 thickening agent Substances 0.000 description 1
238000002834 transmittance Methods 0.000 description 1

Landscapes

Medicinal Preparation (AREA)
Medicines Containing Plant Substances (AREA)

JP59071187A 1984-04-09 1984-04-09 水性液剤不溶成分の分離法 Granted JPS60222412A (ja)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
JP59071187A JPS60222412A (ja)	1984-04-09	1984-04-09	水性液剤不溶成分の分離法

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP59071187A JPS60222412A (ja)	1984-04-09	1984-04-09	水性液剤不溶成分の分離法

Publications (2)

Publication Number	Publication Date
JPS60222412A true JPS60222412A (ja)	1985-11-07
JPS625888B2 JPS625888B2 (de)	1987-02-07

Family

ID=13453401

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP59071187A Granted JPS60222412A (ja)	1984-04-09	1984-04-09	水性液剤不溶成分の分離法

Country Status (1)

Country	Link
JP (1)	JPS60222412A (de)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH01313435A (ja) *	1988-05-16	1989-12-18	Young S Kim	牛黄清心液及びその製造方法
JPH04134032A (ja) *	1990-09-25	1992-05-07	Shiga Pref Gov Seiyaku Kk	安定なイカリイン含有内服液剤
FR2682007A1 (fr) *	1991-10-08	1993-04-09	Goemar Laboratoires	Procede de traitement de produits derives de vegetaux, notamment d'origine marine.
FR2682008A1 (fr) *	1991-10-08	1993-04-09	Goemar Laboratoires	Nouvelles compositions derivees d'algues marines, leurs procedes de preparation et applications dans le domaine agricole.
JPH07101834A (ja) *	1993-08-09	1995-04-18	Tsumura & Co	育毛用エアゾール製剤
EP0826372A3 (de) *	1996-09-03	1998-07-08	Emil Flachsmann AG	Verfahren zur Herstellung eines stabilen, homogenen, von Folgeprodukten freien oder nahezu freien Extraktes

1984
- 1984-04-09 JP JP59071187A patent/JPS60222412A/ja active Granted

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH01313435A (ja) *	1988-05-16	1989-12-18	Young S Kim	牛黄清心液及びその製造方法
JPH04134032A (ja) *	1990-09-25	1992-05-07	Shiga Pref Gov Seiyaku Kk	安定なイカリイン含有内服液剤
FR2682007A1 (fr) *	1991-10-08	1993-04-09	Goemar Laboratoires	Procede de traitement de produits derives de vegetaux, notamment d'origine marine.
FR2682008A1 (fr) *	1991-10-08	1993-04-09	Goemar Laboratoires	Nouvelles compositions derivees d'algues marines, leurs procedes de preparation et applications dans le domaine agricole.
WO1993006730A1 (fr) *	1991-10-08	1993-04-15	Laboratoires Goemar	Nouvelles compositions derivees d'algues marines, leurs procedes de preparation et applications dans le domaine agricole
JPH07101834A (ja) *	1993-08-09	1995-04-18	Tsumura & Co	育毛用エアゾール製剤
EP0826372A3 (de) *	1996-09-03	1998-07-08	Emil Flachsmann AG	Verfahren zur Herstellung eines stabilen, homogenen, von Folgeprodukten freien oder nahezu freien Extraktes

Also Published As

Publication number	Publication date
JPS625888B2 (de)	1987-02-07

Publication	Publication Date	Title
JPH0724560B2 (ja)	1995-03-22	植物体エキス含有飲料
JPH0465051B2 (de)	1992-10-16
JPS625888B2 (de)	1987-02-07
JPS61268627A (ja)	1986-11-28	水性液剤の製法
WO1992022307A1 (fr)	1992-12-23	Medicament contre le syndrome de la fatigue chronique
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