JPS60260520A - 医薬組成物 - Google Patents

医薬組成物

Info

Publication number: JPS60260520A
Authority: JP; Japan
Prior art keywords: active ingredient; stalk; drug composition; group; accumulation
Prior art date: 1984-06-07
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

JP59117957A

Other languages

English (en)

Japanese (ja)

Other versions

JPH043365B2 (fr

Inventor

Takumichi Okuda

奥田　拓道

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Individual

Original Assignee

Individual

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-06-07

Filing date

1984-06-07

Publication date

1985-12-23

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=14724425&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JPS60260520(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1984-06-07 Application filed by Individual filed Critical Individual

1984-06-07 Priority to JP59117957A priority Critical patent/JPS60260520A/ja

1985-12-23 Publication of JPS60260520A publication Critical patent/JPS60260520A/ja

1992-01-23 Publication of JPH043365B2 publication Critical patent/JPH043365B2/ja

Status Granted legal-status Critical Current

Links

229940079593 drug Drugs 0.000 title abstract description 12
239000003814 drug Substances 0.000 title abstract description 12
239000000203 mixture Substances 0.000 title abstract 3
239000004480 active ingredient Substances 0.000 claims abstract description 11
235000005769 Japanese ginseng Nutrition 0.000 claims description 11
241000168720 Panax japonicus Species 0.000 claims description 11
235000003174 Panax japonicus Nutrition 0.000 claims description 11
239000008194 pharmaceutical composition Substances 0.000 claims description 4
239000002775 capsule Substances 0.000 abstract description 7
241000196324 Embryophyta Species 0.000 abstract description 6
XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 abstract description 6
238000009825 accumulation Methods 0.000 abstract description 6
210000004185 liver Anatomy 0.000 abstract description 6
230000002503 metabolic effect Effects 0.000 abstract description 5
BGEBZHIAGXMEMV-UHFFFAOYSA-N 5-methoxypsoralen Chemical compound O1C(=O)C=CC2=C1C=C1OC=CC1=C2OC BGEBZHIAGXMEMV-UHFFFAOYSA-N 0.000 abstract description 4
ZCCUUQDIBDJBTK-UHFFFAOYSA-N psoralen Chemical compound C1=C2OC(=O)C=CC2=CC2=C1OC=C2 ZCCUUQDIBDJBTK-UHFFFAOYSA-N 0.000 abstract description 4
SFLSHLFXELFNJZ-QMMMGPOBSA-N (-)-norepinephrine Chemical compound NC[C@H](O)C1=CC=C(O)C(O)=C1 SFLSHLFXELFNJZ-QMMMGPOBSA-N 0.000 abstract description 2
VXGRJERITKFWPL-UHFFFAOYSA-N 4',5'-Dihydropsoralen Natural products C1=C2OC(=O)C=CC2=CC2=C1OCC2 VXGRJERITKFWPL-UHFFFAOYSA-N 0.000 abstract description 2
DBMJZOMNXBSRED-UHFFFAOYSA-N Bergamottin Natural products O1C(=O)C=CC2=C1C=C1OC=CC1=C2OCC=C(C)CCC=C(C)C DBMJZOMNXBSRED-UHFFFAOYSA-N 0.000 abstract description 2
229960002045 bergapten Drugs 0.000 abstract description 2
KGZDKFWCIPZMRK-UHFFFAOYSA-N bergapten Natural products COC1C2=C(Cc3ccoc13)C=CC(=O)O2 KGZDKFWCIPZMRK-UHFFFAOYSA-N 0.000 abstract description 2
150000003943 catecholamines Chemical class 0.000 abstract description 2
230000002401 inhibitory effect Effects 0.000 abstract description 2
SFLSHLFXELFNJZ-UHFFFAOYSA-N norepinephrine Natural products NCC(O)C1=CC=C(O)C(O)=C1 SFLSHLFXELFNJZ-UHFFFAOYSA-N 0.000 abstract description 2
229960002748 norepinephrine Drugs 0.000 abstract description 2
239000003960 organic solvent Substances 0.000 abstract description 2
230000003405 preventing effect Effects 0.000 abstract description 2
241001063953 Angelica shikokiana Species 0.000 abstract 3
210000000056 organ Anatomy 0.000 abstract 2
239000003925 fat Substances 0.000 abstract 1
150000002978 peroxides Chemical class 0.000 abstract 1
239000006187 pill Substances 0.000 abstract 1
239000003826 tablet Substances 0.000 abstract 1
238000012360 testing method Methods 0.000 description 13
241000700159 Rattus Species 0.000 description 11
239000002285 corn oil Substances 0.000 description 11
235000005687 corn oil Nutrition 0.000 description 11
HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 10
241000208340 Araliaceae Species 0.000 description 9
235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 description 9
235000003140 Panax quinquefolius Nutrition 0.000 description 9
235000008434 ginseng Nutrition 0.000 description 9
UCTWMZQNUQWSLP-UHFFFAOYSA-N adrenaline Chemical compound CNCC(O)C1=CC=C(O)C(O)=C1 UCTWMZQNUQWSLP-UHFFFAOYSA-N 0.000 description 8
230000000694 effects Effects 0.000 description 7
-1 lipid peroxide Chemical class 0.000 description 7
241001465754 Metazoa Species 0.000 description 6
238000002474 experimental method Methods 0.000 description 6
NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 description 6
235000012000 cholesterol Nutrition 0.000 description 5
150000002632 lipids Chemical class 0.000 description 5
240000004808 Saccharomyces cerevisiae Species 0.000 description 4
239000007787 solid Substances 0.000 description 4
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
102000004877 Insulin Human genes 0.000 description 3
108090001061 Insulin Proteins 0.000 description 3
230000003247 decreasing effect Effects 0.000 description 3
235000013402 health food Nutrition 0.000 description 3
229940125396 insulin Drugs 0.000 description 3
238000000034 method Methods 0.000 description 3
230000007935 neutral effect Effects 0.000 description 3
239000000546 pharmaceutical excipient Substances 0.000 description 3
239000000843 powder Substances 0.000 description 3
210000002966 serum Anatomy 0.000 description 3
241000208173 Apiaceae Species 0.000 description 2
102000002322 Egg Proteins Human genes 0.000 description 2
108010000912 Egg Proteins Proteins 0.000 description 2
PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 2
108010023302 HDL Cholesterol Proteins 0.000 description 2
206010067125 Liver injury Diseases 0.000 description 2
239000011230 binding agent Substances 0.000 description 2
210000000748 cardiovascular system Anatomy 0.000 description 2
235000013345 egg yolk Nutrition 0.000 description 2
210000002969 egg yolk Anatomy 0.000 description 2
231100000234 hepatic damage Toxicity 0.000 description 2
230000008818 liver damage Effects 0.000 description 2
239000000314 lubricant Substances 0.000 description 2
239000000463 material Substances 0.000 description 2
239000003921 oil Substances 0.000 description 2
235000019198 oils Nutrition 0.000 description 2
238000002360 preparation method Methods 0.000 description 2
240000002234 Allium sativum Species 0.000 description 1
239000005995 Aluminium silicate Substances 0.000 description 1
229920002134 Carboxymethyl cellulose Polymers 0.000 description 1
FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical class OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 description 1
102000004190 Enzymes Human genes 0.000 description 1
108090000790 Enzymes Proteins 0.000 description 1
108010010803 Gelatin Proteins 0.000 description 1
108010010234 HDL Lipoproteins Proteins 0.000 description 1
208000031226 Hyperlipidaemia Diseases 0.000 description 1
206010020772 Hypertension Diseases 0.000 description 1
229930195725 Mannitol Natural products 0.000 description 1
241000277269 Oncorhynchus masou Species 0.000 description 1
229920002472 Starch Polymers 0.000 description 1
239000013543 active substance Substances 0.000 description 1
235000010443 alginic acid Nutrition 0.000 description 1
229920000615 alginic acid Polymers 0.000 description 1
235000012211 aluminium silicate Nutrition 0.000 description 1
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
239000000440 bentonite Substances 0.000 description 1
229910000278 bentonite Inorganic materials 0.000 description 1
SVPXDRXYRYOSEX-UHFFFAOYSA-N bentoquatam Chemical compound O.O=[Si]=O.O=[Al]O[Al]=O SVPXDRXYRYOSEX-UHFFFAOYSA-N 0.000 description 1
230000015572 biosynthetic process Effects 0.000 description 1
210000004369 blood Anatomy 0.000 description 1
239000008280 blood Substances 0.000 description 1
210000004204 blood vessel Anatomy 0.000 description 1
230000037396 body weight Effects 0.000 description 1
239000001768 carboxy methyl cellulose Substances 0.000 description 1
235000010948 carboxy methyl cellulose Nutrition 0.000 description 1
239000008112 carboxymethyl-cellulose Substances 0.000 description 1
239000001913 cellulose Chemical class 0.000 description 1
229920002678 cellulose Chemical class 0.000 description 1
235000010980 cellulose Nutrition 0.000 description 1
239000003153 chemical reaction reagent Substances 0.000 description 1
239000003795 chemical substances by application Substances 0.000 description 1
238000007796 conventional method Methods 0.000 description 1
230000000916 dilatatory effect Effects 0.000 description 1
201000010099 disease Diseases 0.000 description 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
238000001035 drying Methods 0.000 description 1
235000004611 garlic Nutrition 0.000 description 1
229940029982 garlic powder Drugs 0.000 description 1
229920000159 gelatin Polymers 0.000 description 1
239000008273 gelatin Substances 0.000 description 1
235000019322 gelatine Nutrition 0.000 description 1
235000011852 gelatine desserts Nutrition 0.000 description 1
235000011187 glycerol Nutrition 0.000 description 1
230000002440 hepatic effect Effects 0.000 description 1
241000411851 herbal medicine Species 0.000 description 1
201000001421 hyperglycemia Diseases 0.000 description 1
239000004615 ingredient Substances 0.000 description 1
NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 description 1
230000004130 lipolysis Effects 0.000 description 1
239000002075 main ingredient Substances 0.000 description 1
239000000594 mannitol Substances 0.000 description 1
235000010355 mannitol Nutrition 0.000 description 1
239000012046 mixed solvent Substances 0.000 description 1
229910052760 oxygen Inorganic materials 0.000 description 1
239000001301 oxygen Substances 0.000 description 1
239000008177 pharmaceutical agent Substances 0.000 description 1
230000001766 physiological effect Effects 0.000 description 1
239000001267 polyvinylpyrrolidone Substances 0.000 description 1
229920000036 polyvinylpyrrolidone Polymers 0.000 description 1
235000013855 polyvinylpyrrolidone Nutrition 0.000 description 1
230000002265 prevention Effects 0.000 description 1
239000002994 raw material Substances 0.000 description 1
230000028327 secretion Effects 0.000 description 1
238000000638 solvent extraction Methods 0.000 description 1
238000001179 sorption measurement Methods 0.000 description 1
239000008107 starch Substances 0.000 description 1
235000019698 starch Nutrition 0.000 description 1
238000013517 stratification Methods 0.000 description 1
239000000126 substance Substances 0.000 description 1
235000000346 sugar Nutrition 0.000 description 1
230000002889 sympathetic effect Effects 0.000 description 1
208000024891 symptom Diseases 0.000 description 1
238000003786 synthesis reaction Methods 0.000 description 1
229940126680 traditional chinese medicines Drugs 0.000 description 1
230000025033 vasoconstriction Effects 0.000 description 1
239000011782 vitamin Substances 0.000 description 1
229940088594 vitamin Drugs 0.000 description 1
229930003231 vitamin Natural products 0.000 description 1
235000013343 vitamin Nutrition 0.000 description 1
238000005303 weighing Methods 0.000 description 1

Landscapes

Medicines Containing Plant Substances (AREA)

JP59117957A 1984-06-07 1984-06-07 医薬組成物 Granted JPS60260520A (ja)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
JP59117957A JPS60260520A (ja)	1984-06-07	1984-06-07	医薬組成物

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP59117957A JPS60260520A (ja)	1984-06-07	1984-06-07	医薬組成物

Publications (2)

Publication Number	Publication Date
JPS60260520A true JPS60260520A (ja)	1985-12-23
JPH043365B2 JPH043365B2 (fr)	1992-01-23

Family

ID=14724425

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP59117957A Granted JPS60260520A (ja)	1984-06-07	1984-06-07	医薬組成物

Country Status (1)

Country	Link
JP (1)	JPS60260520A (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2006082743A1 (fr) *	2005-02-04	2006-08-10	Takara Bio Inc.	Agent therapeutique
JP2016172711A (ja) *	2015-03-16	2016-09-29	国立大学法人九州大学	血液凝固阻害剤及び血液凝固阻害剤の生産方法

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2000027224A1 (fr) *	1998-11-11	2000-05-18	Manabu Nomura	Produits alimentaires favorables a la sante
JP6065289B2 (ja) *	2013-05-09	2017-01-25	国立大学法人九州大学	抽出方法、美白化粧品を生産する方法及びヘアケア製品を生産する方法

1984
- 1984-06-07 JP JP59117957A patent/JPS60260520A/ja active Granted

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2006082743A1 (fr) *	2005-02-04	2006-08-10	Takara Bio Inc.	Agent therapeutique
JP2016172711A (ja) *	2015-03-16	2016-09-29	国立大学法人九州大学	血液凝固阻害剤及び血液凝固阻害剤の生産方法

Also Published As

Publication number	Publication date
JPH043365B2 (fr)	1992-01-23

Legal Events

Date	Code	Title	Description
2004-06-07	EXPY	Cancellation because of completion of term

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JPS60260520A - 医薬組成物 - Google Patents

Info

Links

Landscapes

Priority Applications (1)

Applications Claiming Priority (1)

Publications (2)

Family

ID=14724425

Family Applications (1)

Country Status (1)

Cited By (2)

Families Citing this family (2)

Cited By (2)

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