JPS6027375B2 - 光学的分析装置に使用するための測定流体の準備用装置 - Google Patents

光学的分析装置に使用するための測定流体の準備用装置

Info

Publication number: JPS6027375B2
Authority: JP; Japan
Prior art keywords: capillary tube; container; sample; capillary; reaction solution
Prior art date: 1977-05-14
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

JP53055743A

Other languages

English (en)

Japanese (ja)

Other versions

JPS53141688A (en

Inventor

ゲオルク・フランク

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Bayer AG

Original Assignee

Bayer AG

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1977-05-14

Filing date

1978-05-12

Publication date

1985-06-28

1978-05-12 Application filed by Bayer AG filed Critical Bayer AG

1978-12-09 Publication of JPS53141688A publication Critical patent/JPS53141688A/ja

1985-06-28 Publication of JPS6027375B2 publication Critical patent/JPS6027375B2/ja

Status Expired legal-status Critical Current

Links

239000012530 fluid Substances 0.000 title claims description 29
238000002360 preparation method Methods 0.000 title claims description 14
230000003287 optical effect Effects 0.000 title claims description 9
238000005259 measurement Methods 0.000 claims description 48
238000000034 method Methods 0.000 claims description 47
239000000243 solution Substances 0.000 claims description 40
210000004369 blood Anatomy 0.000 claims description 36
239000008280 blood Substances 0.000 claims description 36
RLFWWDJHLFCNIJ-UHFFFAOYSA-N 4-aminoantipyrine Chemical compound CN1C(C)=C(N)C(=O)N1C1=CC=CC=C1 RLFWWDJHLFCNIJ-UHFFFAOYSA-N 0.000 claims description 35
238000006243 chemical reaction Methods 0.000 claims description 31
HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 claims description 26
239000000203 mixture Substances 0.000 claims description 25
238000004458 analytical method Methods 0.000 claims description 23
102000004190 Enzymes Human genes 0.000 claims description 20
108090000790 Enzymes Proteins 0.000 claims description 20
229940088598 enzyme Drugs 0.000 claims description 20
210000002966 serum Anatomy 0.000 claims description 19
239000008103 glucose Substances 0.000 claims description 17
WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims description 16
BPYKTIZUTYGOLE-IFADSCNNSA-N Bilirubin Chemical compound N1C(=O)C(C)=C(C=C)\C1=C\C1=C(C)C(CCC(O)=O)=C(CC2=C(C(C)=C(\C=C/3C(=C(C=C)C(=O)N\3)C)N2)CCC(O)=O)N1 BPYKTIZUTYGOLE-IFADSCNNSA-N 0.000 claims description 14
108010054147 Hemoglobins Proteins 0.000 claims description 14
102000001554 Hemoglobins Human genes 0.000 claims description 14
239000000376 reactant Substances 0.000 claims description 14
ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 claims description 13
235000012000 cholesterol Nutrition 0.000 claims description 13
102000003992 Peroxidases Human genes 0.000 claims description 11
NNFCIKHAZHQZJG-UHFFFAOYSA-N potassium cyanide Chemical compound [K+].N#[C-] NNFCIKHAZHQZJG-UHFFFAOYSA-N 0.000 claims description 11
OKKJLVBELUTLKV-UHFFFAOYSA-N methanol Substances OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims description 10
108010015776 Glucose oxidase Proteins 0.000 claims description 9
239000004366 Glucose oxidase Substances 0.000 claims description 9
BAWFJGJZGIEFAR-NNYOXOHSSA-N NAD zwitterion Chemical compound NC(=O)C1=CC=C[N+]([C@H]2[C@@H]([C@H](O)[C@@H](COP([O-])(=O)OP(O)(=O)OC[C@@H]3[C@H]([C@@H](O)[C@@H](O3)N3C4=NC=NC(N)=C4N=C3)O)O2)O)=C1 BAWFJGJZGIEFAR-NNYOXOHSSA-N 0.000 claims description 9
229940116332 glucose oxidase Drugs 0.000 claims description 9
235000019420 glucose oxidase Nutrition 0.000 claims description 9
102000003914 Cholinesterases Human genes 0.000 claims description 7
108090000322 Cholinesterases Proteins 0.000 claims description 7
108010050375 Glucose 1-Dehydrogenase Proteins 0.000 claims description 7
229940048961 cholinesterase Drugs 0.000 claims description 7
230000000694 effects Effects 0.000 claims description 7
230000002255 enzymatic effect Effects 0.000 claims description 7
108010046301 glucose peroxidase Proteins 0.000 claims description 6
NYBKRNICRGLHMH-UHFFFAOYSA-M 2,5-dichlorobenzenediazonium;chloride Chemical compound [Cl-].ClC1=CC=C(Cl)C([N+]#N)=C1 NYBKRNICRGLHMH-UHFFFAOYSA-M 0.000 claims description 5
108010089254 Cholesterol oxidase Proteins 0.000 claims description 5
108010055297 Sterol Esterase Proteins 0.000 claims description 5
102000000019 Sterol Esterase Human genes 0.000 claims description 5
108040007629 peroxidase activity proteins Proteins 0.000 claims description 5
VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims description 4
ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 claims description 4
FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 4
239000002253 acid Substances 0.000 claims description 4
SNRUBQQJIBEYMU-UHFFFAOYSA-N dodecane Chemical compound CCCCCCCCCCCC SNRUBQQJIBEYMU-UHFFFAOYSA-N 0.000 claims description 4
239000008055 phosphate buffer solution Substances 0.000 claims description 4
229910052700 potassium Inorganic materials 0.000 claims description 4
239000011591 potassium Substances 0.000 claims description 4
230000015572 biosynthetic process Effects 0.000 claims description 3
239000011780 sodium chloride Substances 0.000 claims description 2
239000007790 solid phase Substances 0.000 claims description 2
229910019142 PO4 Inorganic materials 0.000 claims 2
239000010452 phosphate Substances 0.000 claims 2
LWIHDJKSTIGBAC-UHFFFAOYSA-K tripotassium phosphate Chemical compound [K+].[K+].[K+].[O-]P([O-])([O-])=O LWIHDJKSTIGBAC-UHFFFAOYSA-K 0.000 claims 2
NTBLZMAMTZXLBP-UHFFFAOYSA-M 2-acetylsulfanylethyl(trimethyl)azanium;iodide Chemical compound [I-].CC(=O)SCC[N+](C)(C)C NTBLZMAMTZXLBP-UHFFFAOYSA-M 0.000 claims 1
RMMXTBMQSGEXHJ-UHFFFAOYSA-N Aminophenazone Chemical compound O=C1C(N(C)C)=C(C)N(C)N1C1=CC=CC=C1 RMMXTBMQSGEXHJ-UHFFFAOYSA-N 0.000 claims 1
229960000212 aminophenazone Drugs 0.000 claims 1
229940101270 nicotinamide adenine dinucleotide (nad) Drugs 0.000 claims 1
NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 claims 1
125000002467 phosphate group Chemical group [H]OP(=O)(O[H])O[*] 0.000 claims 1
229910000160 potassium phosphate Inorganic materials 0.000 claims 1
235000011009 potassium phosphates Nutrition 0.000 claims 1
239000003153 chemical reaction reagent Substances 0.000 description 62
239000004033 plastic Substances 0.000 description 40
229920003023 plastic Polymers 0.000 description 40
239000011521 glass Substances 0.000 description 35
238000012360 testing method Methods 0.000 description 29
238000002835 absorbance Methods 0.000 description 18
230000035484 reaction time Effects 0.000 description 13
239000002904 solvent Substances 0.000 description 9
229950006238 nadide Drugs 0.000 description 8
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 8
YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 description 6
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 6
239000004793 Polystyrene Substances 0.000 description 5
230000000052 comparative effect Effects 0.000 description 5
238000002474 experimental method Methods 0.000 description 5
229960005222 phenazone Drugs 0.000 description 5
238000005375 photometry Methods 0.000 description 5
229920002223 polystyrene Polymers 0.000 description 5
230000035945 sensitivity Effects 0.000 description 5
239000000725 suspension Substances 0.000 description 5
XFXPMWWXUTWYJX-UHFFFAOYSA-N Cyanide Chemical compound N#[C-] XFXPMWWXUTWYJX-UHFFFAOYSA-N 0.000 description 4
238000008050 Total Bilirubin Reagent Methods 0.000 description 4
XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 4
229910052782 aluminium Inorganic materials 0.000 description 4
239000003599 detergent Substances 0.000 description 4
239000011888 foil Substances 0.000 description 4
238000007789 sealing Methods 0.000 description 4
MPHSORCNUGSJAA-UHFFFAOYSA-N 2,5-dichlorobenzenediazonium Chemical class ClC1=CC=C(Cl)C([N+]#N)=C1 MPHSORCNUGSJAA-UHFFFAOYSA-N 0.000 description 3
KIUMMUBSPKGMOY-UHFFFAOYSA-N 3,3'-Dithiobis(6-nitrobenzoic acid) Chemical compound C1=C([N+]([O-])=O)C(C(=O)O)=CC(SSC=2C=C(C(=CC=2)[N+]([O-])=O)C(O)=O)=C1 KIUMMUBSPKGMOY-UHFFFAOYSA-N 0.000 description 3
QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 3
UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 3
HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
239000000853 adhesive Substances 0.000 description 3
230000001070 adhesive effect Effects 0.000 description 3
239000007853 buffer solution Substances 0.000 description 3
238000006911 enzymatic reaction Methods 0.000 description 3
230000002489 hematologic effect Effects 0.000 description 3
238000004519 manufacturing process Methods 0.000 description 3
238000012856 packing Methods 0.000 description 3
150000004965 peroxy acids Chemical class 0.000 description 3
239000008363 phosphate buffer Substances 0.000 description 3
239000007787 solid Substances 0.000 description 3
238000012549 training Methods 0.000 description 3
SCYULBFZEHDVBN-UHFFFAOYSA-N 1,1-Dichloroethane Chemical compound CC(Cl)Cl SCYULBFZEHDVBN-UHFFFAOYSA-N 0.000 description 2
GFFIJCYHQYHUHB-UHFFFAOYSA-N 2-acetylsulfanylethyl(trimethyl)azanium Chemical compound CC(=O)SCC[N+](C)(C)C GFFIJCYHQYHUHB-UHFFFAOYSA-N 0.000 description 2
HQAPREJURVMGMB-UHFFFAOYSA-M 2-acetylsulfanylethyl(trimethyl)azanium;bromide Chemical compound [Br-].CC(=O)SCC[N+](C)(C)C HQAPREJURVMGMB-UHFFFAOYSA-M 0.000 description 2
RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 2
241000277331 Salmonidae Species 0.000 description 2
XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 2
BFNBIHQBYMNNAN-UHFFFAOYSA-N ammonium sulfate Chemical compound N.N.OS(O)(=O)=O BFNBIHQBYMNNAN-UHFFFAOYSA-N 0.000 description 2
229910052921 ammonium sulfate Inorganic materials 0.000 description 2
235000011130 ammonium sulphate Nutrition 0.000 description 2
238000004820 blood count Methods 0.000 description 2
DDRJAANPRJIHGJ-UHFFFAOYSA-N creatinine Chemical compound CN1CC(=O)NC1=N DDRJAANPRJIHGJ-UHFFFAOYSA-N 0.000 description 2
108010071981 cyanhemoglobin Proteins 0.000 description 2
230000007423 decrease Effects 0.000 description 2
239000010432 diamond Substances 0.000 description 2
229910003460 diamond Inorganic materials 0.000 description 2
239000012153 distilled water Substances 0.000 description 2
239000007789 gas Substances 0.000 description 2
239000000546 pharmaceutical excipient Substances 0.000 description 2
239000001397 quillaja saponaria molina bark Substances 0.000 description 2
229930182490 saponin Natural products 0.000 description 2
150000007949 saponins Chemical class 0.000 description 2
238000003860 storage Methods 0.000 description 2
239000000126 substance Substances 0.000 description 2
238000012546 transfer Methods 0.000 description 2
102000003925 1,4-alpha-Glucan Branching Enzyme Human genes 0.000 description 1
108090000344 1,4-alpha-Glucan Branching Enzyme Proteins 0.000 description 1
ICVRSZZKVKXKIV-UHFFFAOYSA-M 2,6-dichlorobenzenediazonium;chloride Chemical compound [Cl-].ClC1=CC=CC(Cl)=C1[N+]#N ICVRSZZKVKXKIV-UHFFFAOYSA-M 0.000 description 1
SWFLNTWSAJTXAS-UHFFFAOYSA-N 3,5-dichlorobenzenediazonium Chemical class ClC1=CC(Cl)=CC([N+]#N)=C1 SWFLNTWSAJTXAS-UHFFFAOYSA-N 0.000 description 1
UEUIKXVPXLWUDU-UHFFFAOYSA-N 4-diazoniobenzenesulfonate Chemical compound [O-]S(=O)(=O)C1=CC=C([N+]#N)C=C1 UEUIKXVPXLWUDU-UHFFFAOYSA-N 0.000 description 1
GANZODCWZFAEGN-UHFFFAOYSA-N 5-mercapto-2-nitro-benzoic acid Chemical compound OC(=O)C1=CC(S)=CC=C1[N+]([O-])=O GANZODCWZFAEGN-UHFFFAOYSA-N 0.000 description 1
108010029731 6-phosphogluconolactonase Proteins 0.000 description 1
102100031126 6-phosphogluconolactonase Human genes 0.000 description 1
RGHNJXZEOKUKBD-UHFFFAOYSA-N D-gluconic acid Natural products OCC(O)C(O)C(O)C(O)C(O)=O RGHNJXZEOKUKBD-UHFFFAOYSA-N 0.000 description 1
101100080807 Drosophila melanogaster mt:ND2 gene Proteins 0.000 description 1
RGHNJXZEOKUKBD-SQOUGZDYSA-N Gluconic acid Natural products OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O RGHNJXZEOKUKBD-SQOUGZDYSA-N 0.000 description 1
108010035289 Glucose Dehydrogenases Proteins 0.000 description 1
108010018962 Glucosephosphate Dehydrogenase Proteins 0.000 description 1
206010018910 Haemolysis Diseases 0.000 description 1
102000005548 Hexokinase Human genes 0.000 description 1
108700040460 Hexokinases Proteins 0.000 description 1
101150016680 MT-ND2 gene Proteins 0.000 description 1
102100028488 NADH-ubiquinone oxidoreductase chain 2 Human genes 0.000 description 1
101150102231 ND2 gene Proteins 0.000 description 1
LEHOTFFKMJEONL-UHFFFAOYSA-N Uric Acid Chemical compound N1C(=O)NC(=O)C2=C1NC(=O)N2 LEHOTFFKMJEONL-UHFFFAOYSA-N 0.000 description 1
TVWHNULVHGKJHS-UHFFFAOYSA-N Uric acid Natural products N1C(=O)NC(=O)C2NC(=O)NC21 TVWHNULVHGKJHS-UHFFFAOYSA-N 0.000 description 1
238000010521 absorption reaction Methods 0.000 description 1
239000000654 additive Substances 0.000 description 1
238000004026 adhesive bonding Methods 0.000 description 1
238000012863 analytical testing Methods 0.000 description 1
VEQOALNAAJBPNY-UHFFFAOYSA-N antipyrine Chemical compound CN1C(C)=CC(=O)N1C1=CC=CC=C1 VEQOALNAAJBPNY-UHFFFAOYSA-N 0.000 description 1
239000011230 binding agent Substances 0.000 description 1
210000001124 body fluid Anatomy 0.000 description 1
239000012928 buffer substance Substances 0.000 description 1
239000004202 carbamide Substances 0.000 description 1
-1 chloride 2.5-Dichlorophenyldiazonium chloride Chemical compound 0.000 description 1
GGCLNOIGPMGLDB-GYKMGIIDSA-N cholest-5-en-3-one Chemical compound C1C=C2CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 GGCLNOIGPMGLDB-GYKMGIIDSA-N 0.000 description 1
NYOXRYYXRWJDKP-UHFFFAOYSA-N cholestenone Natural products C1CC2=CC(=O)CCC2(C)C2C1C1CCC(C(C)CCCC(C)C)C1(C)CC2 NYOXRYYXRWJDKP-UHFFFAOYSA-N 0.000 description 1
150000001840 cholesterol esters Chemical class 0.000 description 1
239000012459 cleaning agent Substances 0.000 description 1
239000011248 coating agent Substances 0.000 description 1
238000000576 coating method Methods 0.000 description 1
239000005515 coenzyme Substances 0.000 description 1
229940109239 creatinine Drugs 0.000 description 1
230000006378 damage Effects 0.000 description 1
230000001419 dependent effect Effects 0.000 description 1
238000013461 design Methods 0.000 description 1
238000007598 dipping method Methods 0.000 description 1
238000004090 dissolution Methods 0.000 description 1
238000005516 engineering process Methods 0.000 description 1
238000007824 enzymatic assay Methods 0.000 description 1
238000003028 enzyme activity measurement method Methods 0.000 description 1
239000000945 filler Substances 0.000 description 1
238000009472 formulation Methods 0.000 description 1
239000000174 gluconic acid Substances 0.000 description 1
235000012208 gluconic acid Nutrition 0.000 description 1
239000000383 hazardous chemical Substances 0.000 description 1
108700026427 hemiglobincyanide Proteins 0.000 description 1
108010036302 hemoglobin AS Proteins 0.000 description 1
230000008588 hemolysis Effects 0.000 description 1
238000007654 immersion Methods 0.000 description 1
239000007788 liquid Substances 0.000 description 1
239000000463 material Substances 0.000 description 1
238000002156 mixing Methods 0.000 description 1
229930027945 nicotinamide-adenine dinucleotide Natural products 0.000 description 1
BOPGDPNILDQYTO-NNYOXOHSSA-N nicotinamide-adenine dinucleotide Chemical compound C1=CCC(C(=O)N)=CN1[C@H]1[C@H](O)[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]2[C@H]([C@@H](O)[C@@H](O2)N2C3=NC=NC(N)=C3N=C2)O)O1 BOPGDPNILDQYTO-NNYOXOHSSA-N 0.000 description 1
238000004806 packaging method and process Methods 0.000 description 1
AZQWKYJCGOJGHM-UHFFFAOYSA-N para-benzoquinone Natural products O=C1C=CC(=O)C=C1 AZQWKYJCGOJGHM-UHFFFAOYSA-N 0.000 description 1
OXNIZHLAWKMVMX-UHFFFAOYSA-N picric acid Chemical compound OC1=C([N+]([O-])=O)C=C([N+]([O-])=O)C=C1[N+]([O-])=O OXNIZHLAWKMVMX-UHFFFAOYSA-N 0.000 description 1
239000008057 potassium phosphate buffer Substances 0.000 description 1
239000010453 quartz Substances 0.000 description 1
238000007430 reference method Methods 0.000 description 1
238000011160 research Methods 0.000 description 1
150000003839 salts Chemical class 0.000 description 1
238000001507 sample dispersion Methods 0.000 description 1
238000005070 sampling Methods 0.000 description 1
210000000582 semen Anatomy 0.000 description 1
VYPSYNLAJGMNEJ-UHFFFAOYSA-N silicon dioxide Inorganic materials O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
150000003626 triacylglycerols Chemical class 0.000 description 1
MOJVORNARBTYPV-UHFFFAOYSA-N trimethyl(2-sulfanylethyl)azanium;bromide Chemical compound [Br-].C[N+](C)(C)CCS MOJVORNARBTYPV-UHFFFAOYSA-N 0.000 description 1
238000002604 ultrasonography Methods 0.000 description 1
229940116269 uric acid Drugs 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements

Landscapes

Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Organic Chemistry (AREA)
Hematology (AREA)
Molecular Biology (AREA)
Urology & Nephrology (AREA)
Biotechnology (AREA)
Microbiology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Analytical Chemistry (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Biochemistry (AREA)
Physics & Mathematics (AREA)
Biomedical Technology (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
General Physics & Mathematics (AREA)
General Engineering & Computer Science (AREA)
Cell Biology (AREA)
Biophysics (AREA)
Food Science & Technology (AREA)
Medicinal Chemistry (AREA)
Genetics & Genomics (AREA)
Pathology (AREA)
Investigating Or Analysing Biological Materials (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Optical Measuring Cells (AREA)
Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Investigating Or Analysing Materials By Optical Means (AREA)
Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
Sampling And Sample Adjustment (AREA)

JP53055743A 1977-05-14 1978-05-12 光学的分析装置に使用するための測定流体の準備用装置 Expired JPS6027375B2 (ja)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE2721942A DE2721942C3 (de)	1977-05-14	1977-05-14	Vorrichtung zum Aufbereiten einer Meßflüssigkeit zum Einsatz in analytisch optischen Geräten
DE2721942.7		1977-05-14

Publications (2)

Publication Number	Publication Date
JPS53141688A JPS53141688A (en)	1978-12-09
JPS6027375B2 true JPS6027375B2 (ja)	1985-06-28

Family

ID=6009015

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP53055743A Expired JPS6027375B2 (ja)	1977-05-14	1978-05-12	光学的分析装置に使用するための測定流体の準備用装置

Country Status (13)

Country	Link
JP (1)	JPS6027375B2 (de)
AT (1)	AT371253B (de)
AU (1)	AU514940B2 (de)
BE (1)	BE866993A (de)
BR (1)	BR7803016A (de)
CH (1)	CH637216A5 (de)
DE (1)	DE2721942C3 (de)
ES (1)	ES469792A1 (de)
FR (1)	FR2390724A1 (de)
GB (1)	GB1582224A (de)
IT (1)	IT1094667B (de)
NL (1)	NL190427C (de)
SE (1)	SE7805408L (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2913889A1 (de) *	1979-04-06	1980-10-16	Compur Electronic Gmbh	Verfahren zur kristallinen abscheidung von chromogenen
DE3024835A1 (de) *	1980-07-01	1982-01-28	Bayer Ag, 5090 Leverkusen	Reagenz fuer die haemoglobinbestimmung
US4454235A (en) *	1982-06-01	1984-06-12	Miles Laboratories, Inc.	Capillary tube holder for liquid transfer in immunoassay
DE19835243A1 (de) *	1998-08-04	2000-02-24	Lmb Technologie Gmbh	Vorrichtung und Verfahren zum Bestimmen eines Hämoglobinwerts von Blut
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1977
- 1977-05-14 DE DE2721942A patent/DE2721942C3/de not_active Expired
1978
- 1978-05-10 CH CH509678A patent/CH637216A5/de not_active IP Right Cessation
- 1978-05-11 SE SE7805408A patent/SE7805408L/xx unknown
- 1978-05-11 AU AU36008/78A patent/AU514940B2/en not_active Expired
- 1978-05-12 FR FR7814330A patent/FR2390724A1/fr active Granted
- 1978-05-12 GB GB19197/78A patent/GB1582224A/en not_active Expired
- 1978-05-12 BE BE2056973A patent/BE866993A/xx not_active IP Right Cessation
- 1978-05-12 ES ES469792A patent/ES469792A1/es not_active Expired
- 1978-05-12 JP JP53055743A patent/JPS6027375B2/ja not_active Expired
- 1978-05-12 NL NLAANVRAGE7805189,A patent/NL190427C/xx not_active IP Right Cessation
- 1978-05-12 BR BR7803016A patent/BR7803016A/pt unknown
- 1978-05-12 IT IT23384/78A patent/IT1094667B/it active
- 1978-05-12 AT AT0348578A patent/AT371253B/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
DE2721942B2 (de)	1979-06-07
AU3600878A (en)	1979-11-15
ES469792A1 (es)	1978-12-16
IT1094667B (it)	1985-08-02
GB1582224A (en)	1981-01-07
CH637216A5 (en)	1983-07-15
BE866993A (fr)	1978-11-13
ATA348578A (de)	1982-10-15
JPS53141688A (en)	1978-12-09
AU514940B2 (en)	1981-03-05
BR7803016A (pt)	1979-01-02
NL190427C (nl)	1994-02-16
NL190427B (nl)	1993-09-16
NL7805189A (nl)	1978-11-16
FR2390724B1 (de)	1983-12-30
FR2390724A1 (fr)	1978-12-08
IT7823384A0 (it)	1978-05-12
DE2721942A1 (de)	1978-11-23
SE7805408L (sv)	1978-11-15
DE2721942C3 (de)	1980-02-07
AT371253B (de)	1983-06-10

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