JPS6034957B2 - ペニシラン酸誘導体 - Google Patents

ペニシラン酸誘導体

Info

Publication number
JPS6034957B2
JPS6034957B2 JP53043624A JP4362478A JPS6034957B2 JP S6034957 B2 JPS6034957 B2 JP S6034957B2 JP 53043624 A JP53043624 A JP 53043624A JP 4362478 A JP4362478 A JP 4362478A JP S6034957 B2 JPS6034957 B2 JP S6034957B2
Authority
JP
Japan
Prior art keywords
oxo
carboxylic acid
dimethyl
phenylacetamide
hebutane
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP53043624A
Other languages
English (en)
Japanese (ja)
Other versions
JPS54135767A (en
Inventor
廣 石川
不二男 田房
量之 中川
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Pharmaceutical Co Ltd
Original Assignee
Otsuka Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharmaceutical Co Ltd filed Critical Otsuka Pharmaceutical Co Ltd
Priority to JP53043624A priority Critical patent/JPS6034957B2/ja
Priority to DE19792914258 priority patent/DE2914258A1/de
Priority to DE2953973A priority patent/DE2953973C2/de
Priority to DE2914218A priority patent/DE2914218C2/de
Priority to DE2953974A priority patent/DE2953974C2/de
Priority to IT48691/79A priority patent/IT1162605B/it
Priority to NO79791223A priority patent/NO791223L/no
Priority to US06/028,770 priority patent/US4317820A/en
Priority to IT48690/79A priority patent/IT1196531B/it
Priority to DK149479A priority patent/DK149479A/da
Priority to BE0/194518A priority patent/BE875469A/fr
Priority to BE0/194519A priority patent/BE875470A/fr
Priority to ZA791713A priority patent/ZA791713B/xx
Priority to CA325,375A priority patent/CA1133469A/fr
Priority to CA000325376A priority patent/CA1153374A/fr
Priority to AU46038/79A priority patent/AU524795B2/en
Priority to CH343479A priority patent/CH642081A5/de
Priority to MX797868U priority patent/MX5704E/es
Priority to AT0269079A priority patent/AT368159B/de
Priority to AR276166A priority patent/AR227005A1/es
Priority to AU46037/79A priority patent/AU529330B2/en
Priority to CH343379A priority patent/CH640853A5/de
Priority to ES480281A priority patent/ES480281A1/es
Priority to FI791190A priority patent/FI70219C/fi
Priority to SU792753360A priority patent/SU1151212A3/ru
Priority to PT69473A priority patent/PT69473A/pt
Priority to NLAANVRAGE7902906,A priority patent/NL180589C/xx
Priority to FR7909337A priority patent/FR2422666A1/fr
Priority to FR7909338A priority patent/FR2422658A1/fr
Priority to SE7903297A priority patent/SE7903297L/xx
Priority to GB7913040A priority patent/GB2020279B/en
Priority to GB7913039A priority patent/GB2019844B/en
Priority to SE7903298A priority patent/SE436280B/sv
Priority to NLAANVRAGE7902905,A priority patent/NL180664C/xx
Publication of JPS54135767A publication Critical patent/JPS54135767A/ja
Priority to ES488833A priority patent/ES488833A0/es
Priority to US06/195,691 priority patent/US4416884A/en
Priority to AT95881A priority patent/AT371121B/de
Priority to AR284582A priority patent/AR226883A1/es
Priority to NO84840617A priority patent/NO840617L/no
Publication of JPS6034957B2 publication Critical patent/JPS6034957B2/ja
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/04—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms
    • C07D215/06—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms having only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/18—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/03—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/04—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06—Peri-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
JP53043624A 1978-04-12 1978-04-12 ペニシラン酸誘導体 Expired JPS6034957B2 (ja)

Priority Applications (39)

Application Number Priority Date Filing Date Title
JP53043624A JPS6034957B2 (ja) 1978-04-12 1978-04-12 ペニシラン酸誘導体
DE19792914258 DE2914258A1 (de) 1978-04-12 1979-04-09 Piperazinylbenzoheterozyklische verbindungen, verfahren zu deren herstellung und mittel, welche diese enthalten
DE2953973A DE2953973C2 (fr) 1978-04-12 1979-04-09
DE2914218A DE2914218C2 (de) 1978-04-12 1979-04-09 N-Acylderivate des Ampicillins und Amoxicillins, Verfahren zu deren Herstellung und pharmazeutische Zubereitungen, welche die Verbindungen enthalten
DE2953974A DE2953974C2 (fr) 1978-04-12 1979-04-09
IT48691/79A IT1162605B (it) 1978-04-12 1979-04-10 Composti della serie beta-lattamica procedimento per produrli e preparato farmaceutico che li comprende
NO79791223A NO791223L (no) 1978-04-12 1979-04-10 Fremgangsmaate for fremstilling av beta-laktamforbindelser
US06/028,770 US4317820A (en) 1978-04-12 1979-04-10 β-Lactam series compound and antibacterial pharmaceutical composition containing the same
IT48690/79A IT1196531B (it) 1978-04-12 1979-04-10 Composti piperazinil-benzoeterociclici procedimento per produrli e preparato farmaceutico che li contiene
DK149479A DK149479A (da) 1978-04-12 1979-04-10 Fremgangsmaade til fremstilling af betalactamforbindelser eller farmaceutisk acceptable salte deraf
BE0/194518A BE875469A (fr) 1978-04-12 1979-04-10 Nouveaux composes de type beta-lactame utiles comme agents antimicrobiens et leur procede de preparation
BE0/194519A BE875470A (fr) 1978-04-12 1979-04-10 Composes piperazinyl-benzoheterocycliques, leur preparation et leurs utilisations therapeutiques
ZA791713A ZA791713B (en) 1978-04-12 1979-04-10 Lactam series compound
AR276166A AR227005A1 (es) 1978-04-12 1979-04-11 Un metodo para preparar un oxo-(pirido 3,2,1-jk-carbazol o benzo(ij)-quinolizina o pirrolo 3,2,1-ij-quinolina)-carboxamido-2-fenilacetamido-oxo-tia-1-azabiciclo-(heptano u oct-2-ene)-2-acido carboxilico
CA000325376A CA1153374A (fr) 1978-04-12 1979-04-11 Composes piperazinylbenzoheterocycliques
AU46038/79A AU524795B2 (en) 1978-04-12 1979-04-11 Beta-lactam series compound
CH343479A CH642081A5 (de) 1978-04-12 1979-04-11 Derivate der beta-lactamserie und diese enthaltende pharmazeutische zubereitungen.
MX797868U MX5704E (es) 1978-04-12 1979-04-11 Procedimiento para la preparacion de derivados del acido penicilanico
AT0269079A AT368159B (de) 1978-04-12 1979-04-11 Verfahren zur herstellung von neuen beta-lactam -verbindungen
CA325,375A CA1133469A (fr) 1978-04-12 1979-04-11 COMPOSE DE LA SERIE DU .beta.-LACTAM
AU46037/79A AU529330B2 (en) 1978-04-12 1979-04-11 Piperazinylbenzoheterocyclic compounds
CH343379A CH640853A5 (de) 1978-04-12 1979-04-11 Piperazinylbenzoheterozyklische verbindungen und bakteriostatische zubereitung welche diese enthaelt.
ES480281A ES480281A1 (es) 1978-04-12 1979-04-11 Procedimiento de preparar compuestos de la serie de las be- ta-lactamas y similares.
FI791190A FI70219C (fi) 1978-04-12 1979-04-11 Foerfarande foer framstaellning av en beta-laktamantibiotikumfoerening
SU792753360A SU1151212A3 (ru) 1978-04-12 1979-04-11 Способ получени производных пенициллина или их фармацевтически приемлемых солей (его варианты)
PT69473A PT69473A (en) 1978-04-12 1979-04-11 Process for preparing beta-lactam series compounds
FR7909338A FR2422658A1 (fr) 1978-04-12 1979-04-12 Composes piperazinyl-benzoheterocycliques, leur preparation et leurs utilisations therapeutiques
NLAANVRAGE7902905,A NL180664C (nl) 1978-04-12 1979-04-12 1,8-alkyleen-3-carboxy-4-oxo-7-piperazinochinolinederivaten, werkwijze voor de bereiding daarvan en anti-microbiele preparaten die een dergelijke verbinding als werkzame stof bevatten.
NLAANVRAGE7902906,A NL180589C (nl) 1978-04-12 1979-04-12 Verbindingen met anti-microbiele werking uit de beta-lactamreeks en farmaceutische preparaten die een dergelijke verbinding als werkzame stof bevatten.
SE7903297A SE7903297L (sv) 1978-04-12 1979-04-12 Beta-laktam-foreningar
GB7913040A GB2020279B (en) 1978-04-12 1979-04-12 Piperazinylbenzoheterocyclic compounds
GB7913039A GB2019844B (en) 1978-04-12 1979-04-12 Lactam series compound
SE7903298A SE436280B (sv) 1978-04-12 1979-04-12 Piperazinylbensoheterocykliska foreningar av antimikrobiellt preparat derav
FR7909337A FR2422666A1 (fr) 1978-04-12 1979-04-12 Nouveaux composes de type b-lactame utiles comme agents antimicrobiens et leur procede de preparation
ES488833A ES488833A0 (es) 1978-04-12 1980-01-30 Metodo de preparar compuestos de la serie de las beta-lacta-mas y similares
US06/195,691 US4416884A (en) 1978-04-12 1980-10-09 Piperazinylbenzoheterocyclic compounds
AT95881A AT371121B (de) 1978-04-12 1981-03-02 Verfahren zur herstellung von neuen beta-lactamen -verbindungen
AR284582A AR226883A1 (es) 1978-04-12 1981-03-11 Metodo para preparar un oxo-(pirido(3,2,1-jk)carbazol o benzo(ij)quinolizina o pirrolo(3,2,1-ij)quinolina)-carboxamido-2-fenilacetamido-oxo-tia-1-azabiciclo-(heptano u oct-2-ene)-2-acido carboxilico
NO84840617A NO840617L (no) 1978-04-12 1984-02-20 Analogifremgangsmaate for fremstilling av farmakologisk aktive cefalosporinderivater

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP53043624A JPS6034957B2 (ja) 1978-04-12 1978-04-12 ペニシラン酸誘導体

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP53098535A Division JPS588396B2 (ja) 1978-08-11 1978-08-11 ピリド〔３，２，１↓−ｊｋ〕カルバゾ−ル誘導体

Publications (2)

Publication Number Publication Date
JPS54135767A JPS54135767A (en) 1979-10-22
JPS6034957B2 true JPS6034957B2 (ja) 1985-08-12

Family

ID=12668994

Family Applications (1)

Application Number Title Priority Date Filing Date
JP53043624A Expired JPS6034957B2 (ja) 1978-04-12 1978-04-12 ペニシラン酸誘導体

Country Status (3)

Country Link
JP (1) JPS6034957B2 (fr)
BE (2) BE875470A (fr)
ZA (1) ZA791713B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6118566A (ja) * 1984-07-05 1986-01-27 Toyoda Mach Works Ltd 動力舵取装置の操舵力制御装置

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6019910B2 (ja) * 1979-10-11 1985-05-18 大塚製薬株式会社 ベンゾ〔ｉｊ〕キノリジン−２−カルボン酸誘導体及びその製造法

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6118566A (ja) * 1984-07-05 1986-01-27 Toyoda Mach Works Ltd 動力舵取装置の操舵力制御装置

Also Published As

Publication number Publication date
BE875470A (fr) 1979-10-10
BE875469A (fr) 1979-10-10
JPS54135767A (en) 1979-10-22
ZA791713B (en) 1980-04-30

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