JPS6043323B2 - Oral composition - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION The present invention relates to oral compositions such as toothpaste and profilakis paste, and more specifically to oral compositions containing alumina anhydride (Al2O3) with a gelatinization rate of 15 to 85%. .

Abrasives, which are generally added to oral compositions such as toothpaste and profilakis paste, have a high ability to efficiently remove stains, plaque, food particles, and other substances adhering to teeth by physical action as a tooth cleaning base. , has excellent cleaning ability, mild polishing and polishing properties that do not damage tooth surfaces, and gives excellent gloss to teeth.
What is desired is something that can smooth the tooth surface and prevent the deposition of plaque and tartar.

In this case, the efficiency of physical removal of stains, plaque, food particles, etc. can be increased by increasing the abrasive power of the abrasive. However, increasing the polishing power is generally contradictory to preventing damage to the tooth surface and adding gloss to the tooth surface. It becomes easy to scrape and damage the tooth surface, sometimes causing wedge-shaped defects, and the polishing force is too high, damaging the tooth surface and reducing the gloss of the tooth surface.

In particular, with Profilakis paste, the main purpose is to remove strongly deposited stain, plaque, tartar, etc., so care is taken to ensure that the polishing force is sufficiently large, and consideration is given to damage to the tooth surface. Currently, very little is being done. When brushing teeth, care is taken not to damage the tooth surface, but there are very few things that can improve the gloss of the tooth surface. For this reason, there has been a demand for an abrasive that does not damage tooth surfaces, gives gloss to tooth surfaces, has appropriate abrasive power, and has excellent cleaning effects. The present inventors conducted extensive research in order to meet the above demands, and found that alumina anhydride (A1.O0) with a gelatinization rate of 15 to 85% has a high glossing effect on tooth surfaces, and has a moderate polishing effect. The present invention was based on the discovery that the alumina anhydride has properties suitable as an abrasive and brightener for toothpaste, profilakis paste, etc. It is known that α-alumina anhydride is used as an abrasive for toothpaste and the like. However, conventional α-alumina anhydride has a gelatinization rate of 90%.
However, as shown in the experimental examples described below, particles in the normal particle size range do not have a sufficient gloss imparting effect on the tooth surface, and their abrasive power is too high. In addition to the α type, as alumina anhydride, γ with a gelatinization rate of 0%,
Types such as ni are also known, but these also do not have a sufficient gloss imparting effect. Furthermore, an alumina anhydride with a pregelatinization rate lower than 15% and an alumina anhydride with a pregelatinization rate higher than 85% are mixed, and the apparent pregelatinization rate of the mixture as a whole is 15~15%.
Even if adjusted to a range of 85%, there is no gloss imparting effect.

However, anhydrous alumina with a gelatinization rate of 15 to 85% has an excellent gloss imparting effect, and thus anhydrous alumina with a gelatinization rate of 15 to 85% provides excellent gloss to the tooth surface. This provision is a new finding of the present inventors.

The present invention will be explained in more detail below.

The oral composition according to the present invention contains anhydrous alumina (Al) with a gelatinization rate of 15 to 85%.

By using this type of alumina anhydride, it is possible to impart excellent gloss to the tooth surface, as well as moderate abrasive power and good cleaning power. Note that alumina anhydride with a gelatinization rate of 15 to 85% refers to α-Al2O3, γ-Al2O3, amorphous Al
2O3 etc. are combined in an appropriate proportion, and its alumina anhydride α-Al is determined by X-ray diffraction. Alumina anhydride (α-Al2O3) with 100% alpha conversion rate for O3 peak
When compared with the peak of , the gelatinization rate is 100%.
．． 15-85% of alumina anhydride (α-Al.O3)
refer to something in Specifically, (a) 12) plane and (116) plane are formed between α-Al2O3 with a α-ization rate of 100%.
Find the diffraction X-ray intensity ratio on the surface, and the average value is 15 to 85
Point out what is in %. The above-mentioned alumina anhydride having a pregelatinization rate of 15 to 85% can be produced by the Bayer method, and by appropriately controlling the firing temperature in the production process by the Baier method, the alumina anhydride having the desired pregelatinization rate can be produced by the Baier method. can get things.

As mentioned above, the alumina anhydride used in the present invention has a pregelatinization rate of 15 to 85%, but the pregelatinization rate is in a more preferable range from the viewpoint of imparting gloss to the tooth surface and imparting appropriate polishing power. is 30-75%.

Further, the average particle size of the alumina anhydride used in the present invention is not necessarily limited, but is preferably 10 μm or less,
If the particle size is too large, the gloss imparting effect may deteriorate. In particular, when the gelatinization rate is 60 to 85%, it is most preferable that the average particle size is 5 μm or less in terms of gloss imparting and polishing power. In addition, the amount of alumina anhydride with a gelatinization rate of 15 to 85% is appropriately selected depending on the type of oral composition, purpose of use, etc., and is not particularly limited, but is usually 0.5 to 5%.
It is 0% by weight.

In the present invention, the alumina anhydride having a gelatinization rate of 15 to 85% may be used alone or in combination of two or more.

In addition, alumina anhydride with a gelatinization rate of 15 to 85% may be used in combination with other alumina anhydrides or hydrates, and furthermore may be used in combination with other conventionally known abrasives. No problem. The oral composition according to the present invention can be prepared as dentifrices such as toothpaste, powdered toothpaste, moisturized toothpaste, profilakis paste, etc. Other components of the oral composition of the present invention include Appropriate components depending on the type may be used.

For example, in the case of toothpaste, carboxymethyl cellulose, hydroxyethyl cellulose, alginate,
Binder such as carrageenan, gum arabic, polyvinyl alcohol, thickener such as polyethylene glycol, sorbitol, glycerin, propylene glycol, sodium laur sulfate, sodium dodecylbenzenesulfonate,
Foaming agents such as hydrogenated coconut fatty acid monoglyceride monosulfate sodium, sodium lauryl sulfoacetate, sodium N-lauroyl sarcosinate, N-acyl glutamate, lauroyl diethanolamide, sucrose fatty acid ester, and essential oils such as peppermint, spearmint, etc. - Flavoring materials such as menthol, carvone, eugenol, anethole, etc., sweeteners such as saccharin sodium, stevioside, neohesperidyl dihydrochalcone, glycyrrhizin, perillartine, p-methoxycinnamic aldehyde, thaumatin, preservatives, and lysozyme chloride, dextranase, lytic enzyme,
Mutanase, chlorhexidine or its salt, sorbic acid, alexidine, hinokitiol, cetylpyridinium chloride, alkylglycine, alkyldiaminoethylglycine salt, allantoin, ε-aminocaproic acid,
Tranexamic acid, azulene, vitamin E1 sodium monofluorophosphate, sodium fluoride, stannous fluoride,
Active ingredients such as water-soluble primary or secondary phosphates, quaternary ammonium compounds, sodium chloride, etc. may be blended. In this case, the gelatinization rate used in the present invention is 15 to 85.
% of alumina anhydride stably retains active ingredients such as fluoride, so these active ingredients can be effectively blended. As explained above, the alumina anhydride with a gelatinization rate of 15 to 85% used in the oral composition of the present invention is
It imparts excellent gloss to the tooth surface, smooths the tooth surface, has appropriate abrasive power, and has a good tooth cleaning effect without damaging the tooth surface.

This Yanghe is an alumina anhydride with a normal gelatinization rate of over 90% (
α-． Al2O3) does not have a sufficient tooth surface glossing effect, and alumina anhydride with a gelatinization rate of 90% or more is not combined (for example, alumina anhydride with a gelatinization rate of 90% or more).
-Al2O3) and γ-Al2O3 with a gelatinization rate of 0%), the apparent gelatinization rate of the entire mixture is 15 to 85%.
Even if one adjusted to the above is used, the tooth surface gloss imparting improvement effect does not occur, and the above-mentioned effects are unique to alumina anhydride having a gelatinization rate of 15 to 85%. Next, the effects of the present invention will be specifically explained using experimental examples. Experimental example Average particle diameter 3 to 3 with various gelatinization rates by Beyer method
4μ alumina anhydride (Al.

O3) was produced. In this case, alumina anhydride having a desired gelatinization rate was obtained by appropriately controlling the firing temperature. The relationship between the firing temperature and the gelatinization rate is approximately as follows. The gelatinization rate of the alumina anhydride was determined by measuring the diffraction X-ray intensities at the (4), 12) and (116) planes of the sample alumina anhydride. A
The intensity ratio with l2O3 is (a) 12) plane and (11
6) The surface was determined and averaged to determine the gelatinization rate.

Next, the gloss improvement effect and polishing power of each alumina anhydride was investigated using the following method. Gloss improvement measurement method 5×5T! ! Bovine teeth cut into n-sized pieces were embedded in resin, and the surface of the bovine tooth enamel was smoothed with a rotary polisher, followed by polishing with NOl2OO emery paper, and polishing and buffing with calcium hydrogen phosphate anhydrate. The enamel surface was treated to have a gloss level of 80.0±2.0 using a gloss meter (Nippon Denshoku Kogyo Co., Ltd. GLOSSMETER G-10).

Next, a suspension made by suspending powder (alumina anhydride) 4a1 in 30ml of water was poured into a polishing container in which the above-mentioned cow teeth were set, and a horizontal polishing tester was used to apply a load of 200y1.
Brushing was carried out under the conditions of 7,000 strokes/4 gins, and the increase or decrease in gloss was measured using a gloss meter, and the difference from the initial gloss was defined as the degree of improvement in gloss.

In this case, the level of gloss improvement that is visually recognized as sufficiently glossy is +20 or more, and the level that is recognized as glossy is +15 or more. In addition, as a brushing brush, the number of bristle bundles is 44, and the thickness of the hair is 8 mil (approximately 0.2w0n).
The material was made of nylon (62) with a hair length of 12 wrm, and the hardness of the material was M according to the Household Goods Quality Indication Law.

Polishing force measurement method Using a suspension consisting of 4cI1 of powder (anhydrous alumina) suspended in 30ml of water, J at a load of 200y was used.
A copper plate of ISH-3361 (Vickers hardness 120) was brushed 20,000 times in 2 hours using a horizontal polishing tester (the same brush used in the gloss improvement test was used), and the amount of wear of the copper plate was measured.

The results are shown in Table 1 and Figure 1 (Gloss Improvement) and Figure 2 (Abrasive Power).

For comparison, the degree of gloss improvement of mixtures of alumina anhydrides having different gelatinization rates was investigated in the same manner as above.

The results are also listed in Table 1. From the results in Table 1 and Figures 1 and 2, it is clear that anhydrous alumina with a gelatinization rate of 15 to 85%, especially 30 to 75%, has a good effect on improving tooth enamel gloss and has a moderate polishing power. It is found that On the other hand, it has been found that the usual α-alumina anhydride having a gelatinization rate of 90% or more has a small gloss improvement effect and has the problem of excessively high polishing force. In addition, the normal gelatinization rate is 90%
Even if a mixture of the above α-alumina anhydride and γ-alumina with a gelatinization rate of 0% is used at a weight ratio of 1:1, the effect of improving gloss is small, and those with a different gelatinization rate (the gelatinization rate of the present invention) outside the range), and the mixture as a whole has an apparent α
It was found that even if the gelatinization rate was adjusted to the gelatinization rate range of the present invention, the object of the present invention could not be achieved. Examples are shown below.

In addition, in the compounding amounts of the following examples, all percentages are weight percentages. Examples 1-4

[Brief explanation of the drawing]

FIG. 1 is a graph showing the relationship between the degree of gelatinization of anhydrous alumina and the degree of gloss improvement, and FIG. 2 is a graph showing the relationship between the degree of gelatinization of anhydrous alumina and polishing power.

Claims (1)

[Scope of Claims] 1. An oral composition comprising anhydrous alumina having a gelatinization rate of 15 to 85%. 2. The oral composition according to claim 1, wherein the alumina anhydride has a gelatinization rate of 30 to 75%. 3. The oral cavity composition according to claim 1 or 2, wherein the alumina anhydride has an average particle size of 10 μm or less. 4. The oral composition according to any one of claims 1 to 3, wherein the alumina anhydride is produced by the Bayer process.