JPS6113974A - Ｎｍｒイメージング装置に用いるカテーテル - Google Patents

Ｎｍｒイメージング装置に用いるカテーテル

Info

Publication number
JPS6113974A
JPS6113974A JP60127260A JP12726085A JPS6113974A JP S6113974 A JPS6113974 A JP S6113974A JP 60127260 A JP60127260 A JP 60127260A JP 12726085 A JP12726085 A JP 12726085A JP S6113974 A JPS6113974 A JP S6113974A
Authority
JP
Japan
Prior art keywords
catheter
magnetic
magnetic field
image
sheath
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP60127260A
Other languages
English (en)
Other versions
JPH0649032B2 (ja
Inventor
ロバート・エス・コドリントン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Varian Medical Systems Inc
Original Assignee
Varian Associates Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Varian Associates Inc filed Critical Varian Associates Inc
Publication of JPS6113974A publication Critical patent/JPS6113974A/ja
Publication of JPH0649032B2 publication Critical patent/JPH0649032B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/0105—Steering means as part of the catheter or advancing means; Markers for positioning
    • A61M25/0127—Magnetic means; Magnetic markers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
    • G01R33/285—Invasive instruments, e.g. catheters or biopsy needles, specially adapted for tracking, guiding or visualization by NMR
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
    • A61B2090/3954—Markers, e.g. radio-opaque or breast lesions markers magnetic, e.g. NMR or MRI
    • A61B2090/3958—Markers, e.g. radio-opaque or breast lesions markers magnetic, e.g. NMR or MRI emitting a signal

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Veterinary Medicine (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • General Physics & Mathematics (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Media Introduction/Drainage Providing Device (AREA)

Abstract

(57)【要約】本公報は電子出願前の出願データであるた
め要約のデータは記録されません。

Description

【発明の詳細な説明】 産業上の利用分野 本発明は医療用磁気共鳴イメージングの分野に属し、磁
気共鳴イメージングと共に用いるためのカテーテル装置
に関する。
従来の技術 カテーテル処置は生体内での検出技術の変化に対して改
良されてきた。イメージング手段に関して、カテーテル
装置はカテーテルが用いられるべき特別な処置を完遂す
るために正確に配置されることもある。
核磁気共鳴（ＮＭＲ）イメージングにおいて、干渉性の
核の磁化（該して水素原子核の磁化）の空間密度分布が
描かれ、水素を含む物質に対する走査装置の感度は、も
し後者が、イメージング装置においてその周辺よシも実
質的によく見えるならば、カテーテルの進行の記録のた
めの基磁を形成する。もし、カテーテルの構造上の一部
分が、まわシの組織よシも単に、よシ水素を含んでいる
（ということ）ならば、カテーテルは検知できるが限界
は有効なコントラスト上に置かれる。加えて、カテーテ
ルの近くの周辺にある組織はげやけるかもしれない。更
に、多くのカテーテルは光ガイド、切削装置、電極線及
び体液に対して化学的に不活性な物質でできた半硬性の
外装に含まれる類いのような機能的要素から成る。これ
らの機能的要素は磁気共鳴イメージングを減損する傾向
があシ、交互に、カテーテル末端の臨界位置をよシネ確
定にする分析の損失がある。本発明はＮＭＲコントラス
トの制限をカテーテル先端において局限され、制御可能
な磁場を準備することによって克服し、それによシ、先
端の位置はＮＭＲイメージ内で明白に決定される。
発明の概要 本発明は一対の近接したフォイル導体であって、カテー
テル外装物質内に埋め込まれ、カテーテル先端でルー！
内において電気的に成端しているストリッジライン（５
ｔｒｉｐ　１ｉｎｅ　）によって提供される。導体は外
装の磁化率と実質的に調和するように構成されている。
弱い双極子場は交互のイメージング間隔の間、電流・ぐ
ルスによって励磁され、その結果それら交互のイメージ
ング間隔の間、ＮＭＲイメージの局所的デグラデーショ
ン（ｄｅｇｒａ−４１，１゜。）を起。す。　　　　　
　　　　　　　　　　　髪好適実施例 第１図は本発明のブロック図である。イメージング装置
１０は、数多くの磁気共鳴イメージング装置のどれか１
つである。このような装置は特殊化した磁気モーメント
の分布に対する２次元又は３次元の空間的な感度を示す
。その特別な装置は決定的なものではなく、イメージが
重要な領域で形成されることが必須であるにすぎない。
イメージング装置１０は患者１４に磁場分布Ｈ（ｘ、ｙ
。
ｚ、ｔ）をかけるための装置を有し、ＲＦコイル構造物
１８を介してＲＦ電源から回転磁場が得られる。受信器
２０は共鳴信号に応答し、イメージプロセッサ（ｉｍａ
ｇｅ　ｐｒｏｃｅｓｓｏｒ　）　２２は再び空間関数ｆ
（ｘ、ｙ、ｚ）を構成し、それより所望の投影、例えば
ｆｚ（ｘ、ｙ）がディスプレイ装置２４によって、図的
に描写される。カテーテル制御器２８と共に本発明のカ
テーテル２６が以下のようによシ十分に検討されている
。
第２図を・参照すると、カテーテル構造物の一部の縦断
面図が示されている。外装３０は好適には良い断熱性と
絶縁特性及び比較的低い磁化率の特徴がある強化された
フッ素樹脂で構成される。その目的に適する物質の１つ
はテフロン（Ｔｅｆｌｏｎ　）又はケルＦである。
外装３０はその壁内に一対の導体３２及び３２’が埋め
込まれている。これらは好適には伝導性物質のめっき又
は他の蒸着技術によって得られたフォイル合成物から形
成され、実質的に外装の磁化率と調和する所望の磁化率
の合成物を得る。磁化率を調和させるだめの技術は米国
出願番号第４８２゜３４４号に記載されている。このよ
うにカテーテル・の磁気的不可視性が維持される。
フォイル導体は距離をおいて分離されてス）　ＩＪッグ
ライン（５ｔｒｉｐ　１ｉｎｅ　）を形成し、その距離
は他の導体の大きさに比べて短かい。ストリッ！ライン
上のＡ？ルス伝達は実質的にそれによって制限された領
域に制限され、また、この領域の外部にある孤立した磁
場を効果的に打ち消す。
カテーテルのチップ（ｔｔｐ）　３４は、導体３２及び
３２′を接続するループ３６を有している。ループの平
面は好適にはカテーテル対称軸３７を横断することであ
る。弱いノ４ルス源によって励磁すれるとき、ルーツは
第３図にあるように双極磁場４０を支持し、その磁場は
磁気共鳴イメージングディスプレイ上にイメージカーソ
ルを提供するＮＭＲイメージを局所的にひずませる。カ
ーソルの空間的伸びが最小になるために弱い励磁を用い
る仁とが好ましい。
本発明の主要な目的はカテーテルチップの正確な位置決
め及び監視である。低磁化率の機能的要素である光導体
又はそれと同様のものは、カテーテル外装中に突き通さ
れ、カテーテルは選ばれた血管を通って調査の正常位置
に向けられる。この位置決め操作の間、カテーテルルー
ツの励磁は連続的に近接するＮＭＲイメージ獲得の間じ
ゆう交互に断続する。これはカテーテル制御器２８によ
って達成される。イメージの獲得には２〜３秒間の時間
がかがシ、組になった連続的イメージはカテーテルチッ
プノの位置を強張するために、好適にはプロセッサー２
２によって取替えられるモードと比較される。カテーテ
ル制御器２６とプロセッサ２２の同期化は簡単である。
好適には、プロセッサ２２は交互に連続するイメージを
伴う信号並行を提供してカテーテルチップの弱い磁場４
０を活動化する。取替可能なモードイメージ情報はイメ
ージカーソルを形成し、それは、好適には同じイメージ
の付加されたディスプレイ又はまさにその最も新しい単
一イメージ上に重ねられる。このようにカテーテルチッ
プが置かれるので、低い磁化率の機能的要素が除去され
てもよく、また、所望の要素がカテーテル外装に挿入さ
れてもよい。
このような他の要素は伝導性又は高磁化率を示し、もし
そうでなければ位置決め操作ステツブの間、ＮＭＲイメ
ージに反対の影響を及ぼすとみなせる。
カテーテルチップからのパルス場の使用は、イメージの
計算をカテーテルチップの隣接領域内のピクセルの数に
限定すふことによってスピードアッグされる。この技術
は好適にはカテーテルの先端１中心を置“た３０”拡大
さ１だ”旬−′を　　　１保つための適切なアルｔリズ
ム（ａｌｇｏｒｉｔｈｍ　）と連　　　結される。その
ときＣＲＴディスゾレイは体内を移動するカテーテルの
ある程度即時的な映像を提供する。好適なディスグレイ
モードにおいて、操縦者はフラッシング（ｆｌａｓｈｉ
ｎｇ　）の強さ又は灰色で制御できる対照色に従ってカ
テーテルの先端を見、又、表示されたピクセルの領域内
のＮＭＲ信号の分析を最大化するように選択された色ス
ケールを見る。
【図面の簡単な説明】
第１図は本発明に従った装置のブロック図である。 第２Ａ図は本発明のカテーテにの一部分の縦断面図であ
る。 第２Ｂ図はカテーテルの先端近くの部分の横断面図であ
る。 第３図は使用中のＮＭＲカテーテルの場の略示図である
。 主要符号の説明 １０・−・イメージング装置 ２６・・・カテーテル ３０・・・外装 ３４・・・チップ ３６・・・ループ ４０・・・双極磁場 特許出願人　　Δリアンのアンシエイツ・インコーポレ
イテッド

Claims (1)

  1. 【特許請求の範囲】 １、組合せにおいて患者の組織構成物の特性を表す選択
    された磁気パラメータの空間分布を得るための磁気共鳴
    イメージング装置と前記患者に挿入するためのカテーテ
    ルであって、該カテーテルがその局所付近の磁場を制御
    可能に妨げることに適しているところの組合せ。 ２、カテーテル装置であって、 ａ）屈伸自在に伸びた絶縁体を有する中空外装と、 ｂ）前記絶縁体内に埋められ、実質的にその長さの分だ
    け伸びている一対の伝導性のストリップと、 ｃ）前記外装内に埋められ、その一端に隣接して配列さ
    れた伝導性ループ手段であって、該ループは互いに前記
    伝導性ストリップに接続しているところのループ手段と
    、 ｄ）電流を供給するための励起装置で、その電流は前記
    伝導性ストリップを通り、次に、前記ループを通り、そ
    れによって制御可能な双極磁場が、前記装置の付近で得
    られるところの装置と、 から成るカテーテル装置。 ３、身体内におけるカテーテルの前記身体内との空間的
    関係を調査する方法であって、 ａ）前記カテーテルを前記身体内に導入し、ｂ）前記カ
    テーテルの末端に弱い磁場を励磁し、それによって前記
    磁気イメージを部分的に摂動させ、 ｃ）前記身体の磁気共鳴イメージを形成する、ことより
    成る方法。
JP60127260A 1984-06-18 1985-06-13 Ｎｍｒイメ−ジング装置に用いるカテ−テル Expired - Lifetime JPH0649032B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US621635 1984-06-18
US06/621,635 US4572198A (en) 1984-06-18 1984-06-18 Catheter for use with NMR imaging systems

Publications (2)

Publication Number Publication Date
JPS6113974A true JPS6113974A (ja) 1986-01-22
JPH0649032B2 JPH0649032B2 (ja) 1994-06-29

Family

ID=24490973

Family Applications (1)

Application Number Title Priority Date Filing Date
JP60127260A Expired - Lifetime JPH0649032B2 (ja) 1984-06-18 1985-06-13 Ｎｍｒイメ−ジング装置に用いるカテ−テル

Country Status (5)

Country Link
US (1) US4572198A (ja)
EP (1) EP0165742B1 (ja)
JP (1) JPH0649032B2 (ja)
DE (2) DE165742T1 (ja)
IL (1) IL75378A (ja)

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IL75378A0 (en) 1985-09-29
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US4572198A (en) 1986-02-25
DE3577804D1 (de) 1990-06-28
EP0165742A3 (en) 1987-05-27
EP0165742B1 (en) 1990-05-23
DE165742T1 (de) 1986-08-14
EP0165742A2 (en) 1985-12-27

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