JPS61161258A - １，３，４―三置換アザシクロアルカン及びアザシクロアルケン - Google Patents

１，３，４―三置換アザシクロアルカン及びアザシクロアルケン

Info

Publication number
JPS61161258A
JPS61161258A JP60293362A JP29336285A JPS61161258A JP S61161258 A JPS61161258 A JP S61161258A JP 60293362 A JP60293362 A JP 60293362A JP 29336285 A JP29336285 A JP 29336285A JP S61161258 A JPS61161258 A JP S61161258A
Authority
JP
Japan
Prior art keywords
ethyl
indol
carboxylic acid
salt
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP60293362A
Other languages
English (en)
Japanese (ja)
Inventor
ヴオルフガング・フルーストル
アンゲロ・シユトーニ
ベアト・シユミツツ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of JPS61161258A publication Critical patent/JPS61161258A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/78—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • G—PHYSICS
    • G05—CONTROLLING; REGULATING
    • G05B—CONTROL OR REGULATING SYSTEMS IN GENERAL; FUNCTIONAL ELEMENTS OF SUCH SYSTEMS; MONITORING OR TESTING ARRANGEMENTS FOR SUCH SYSTEMS OR ELEMENTS
    • G05B2219/00—Program-control systems
    • G05B2219/30—Nc systems
    • G05B2219/35—Nc in input of data, input till input file format
    • G05B2219/35287—Verify, check program by drawing, display part, testpiece

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Indole Compounds (AREA)
JP60293362A 1985-01-03 1985-12-27 １，３，４―三置換アザシクロアルカン及びアザシクロアルケン Pending JPS61161258A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH13/85-5 1985-01-03
CH1385 1985-01-03
CH3053/85-0 1985-07-15

Publications (1)

Publication Number Publication Date
JPS61161258A true JPS61161258A (ja) 1986-07-21

Family

ID=4177425

Family Applications (2)

Application Number Title Priority Date Filing Date
JP60293362A Pending JPS61161258A (ja) 1985-01-03 1985-12-27 １，３，４―三置換アザシクロアルカン及びアザシクロアルケン
JP60293363A Pending JPS61161279A (ja) 1985-01-03 1985-12-27 １，３‐ジ置換テトラヒドロピリジン類

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP60293363A Pending JPS61161279A (ja) 1985-01-03 1985-12-27 １，３‐ジ置換テトラヒドロピリジン類

Country Status (12)

Country Link
EP (1) EP0187619A3 (fr)
JP (2) JPS61161258A (fr)
KR (1) KR870006036A (fr)
AU (1) AU5178786A (fr)
DD (1) DD251131A5 (fr)
DK (1) DK886A (fr)
FI (1) FI855182A7 (fr)
GR (1) GR860003B (fr)
HU (1) HUT39442A (fr)
NO (1) NO860008L (fr)
PT (1) PT81781B (fr)
ZA (2) ZA869B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008524276A (ja) * 2004-12-20 2008-07-10 エフ．ホフマン−ラ ロシュ アーゲー ４−アミノピペリジン誘導体

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3907974A1 (de) * 1989-03-11 1990-09-13 Merck Patent Gmbh Indolderivate
US5428043A (en) * 1990-02-08 1995-06-27 Pfizer Inc. Tricyclic-cyclic amines as novel cholinesterase inhibitors
TW197442B (fr) * 1990-02-08 1993-01-01 Pfizer
KR100457857B1 (ko) * 2002-05-23 2004-11-18 (주) 비엔씨바이오팜 2-[2-(3-인돌릴)에틸아미노]피리딘 유도체, 그 제조방법및 이를 포함하는 항바이러스용 약학적 조성물

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3075986A (en) * 1958-01-09 1963-01-29 Rhone Poulenc Sa (1-piperdidylalkyl) derivatives of 3-indole
US3183235A (en) * 1961-06-27 1965-05-11 Sterling Drug Inc 1-[3-, 2-, and 1-indolyl-lower-alkanoyl] piperidines
US3238215A (en) * 1963-10-17 1966-03-01 Sterling Drug Inc 1-[(3-, 2-, and 1-indolyl)-lower-alkyl-, lower-alkenyl-, and lower-alkynyl]piperidines
US3821387A (en) * 1965-10-23 1974-06-28 Robins Co Inc A H The treatment of parkinsonism with 3-(omega-substituted alkyl)-indoles
GB1189064A (en) * 1967-05-01 1970-04-22 Sterling Drug Inc Indole Derivatives
DE3233553A1 (de) * 1982-09-10 1984-03-15 Merck Patent Gmbh, 6100 Darmstadt Pyrrolderivate
DE3342632A1 (de) * 1983-11-25 1985-06-05 Merck Patent Gmbh, 6100 Darmstadt Indolderivate

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008524276A (ja) * 2004-12-20 2008-07-10 エフ．ホフマン−ラ ロシュ アーゲー ４−アミノピペリジン誘導体

Also Published As

Publication number Publication date
EP0187619A3 (fr) 1987-08-26
HUT39442A (en) 1986-09-29
ZA869B (en) 1986-08-27
KR870006036A (ko) 1987-07-08
NO860008L (no) 1986-07-04
JPS61161279A (ja) 1986-07-21
FI855182L (fi) 1986-07-04
GR860003B (en) 1986-04-25
DK886A (da) 1986-07-04
DK886D0 (da) 1986-01-02
DD251131A5 (de) 1987-11-04
FI855182A0 (fi) 1985-12-30
PT81781B (de) 1987-11-05
EP0187619A2 (fr) 1986-07-16
PT81781A (de) 1986-02-01
AU5178786A (en) 1986-07-17
ZA8610B (en) 1986-08-27
FI855182A7 (fi) 1986-07-04

Similar Documents

Publication Publication Date Title
US5834493A (en) Indole derivatives as 5-HT1A and/or 5-HT2 ligands
AU763960B2 (en) Pyrrolidine derivatives-CCR-3 receptor antagonists
FI104631B (fi) Menetelmä uusien 1-asyyli-2-aralkyyli-4-(alkyyli)-aminopiperidiiniyhdisteiden valmistamiseksi
CN1174970C (zh) 3-卤代烷基-1h-吡唑的制备方法
EP0414289B1 (fr) Agents antipsychotiques spirocycliques
RU2095361C1 (ru) Конденсированные гетероциклические соединения, способ их получения и фармацевтическая композиция на их основе
US5116846A (en) N-aralkyl piperidine derivatives as psychotropic drugs
HU221193B1 (en) Neuroprotective indole, qinoline and benzoxazolone derivatives, pharmaceutical compositions comprising such compounds and process for producing them
NZ230068A (en) Indazole-3-carboxylic acid esters and amides of diaza compounds having 6,7, or 8 ring members: preparatory processes and pharmaceutical compositions
CA1246563A (fr) 3-arylcarbonyl- et 3-cycloalcoylcarbonyl-1- aminoalcoyl-1h-indoles utiles comme analgesiques
NZ209279A (en) 3-(piperidinyl)- and 3-(pyrrolidinyl)-1h-indazole derivatives and pharmaceutical compositions
JPH0739387B2 (ja) 新規１−ベンジル−アミノアルキル−ピロリジノン化合物及びその製造方法
JPS6289679A (ja) ピペリジン誘導体
JPS63146874A (ja) インドール誘導体
JPH07506825A (ja) ５−ｈｔ１レセプターアゴニストとしての縮合イミダゾール及びトリアゾール誘導体
CA1337202C (fr) Amides cycliques qui sont des antagonistes des leucotrienes
MXPA97006605A (en) Indol derivatives as antagonists of amino acids exited
CZ292379B6 (cs) Tetrahydrochinolinové deriváty, způsob jejich výroby a farmaceutický prostředek s jejich obsahem
US5708174A (en) Heterocyclic-esters or -amides used as 5-HT4 receptor antagonists
HU177410B (en) Process for preparing new piperidino-propanol derivatives
NZ233645A (en) 3-(hetero)aryl-substituted-3,4 dehydropiperidine derivatives; preparatory processes and pharmaceutical compositions
JPS638382A (ja) 水素添加された１−ベンゾオキサシクロアルキルピリジンカルボン酸化合物，その製造方法及び該化合物を含む医薬製剤
JPS61161258A (ja) １，３，４―三置換アザシクロアルカン及びアザシクロアルケン
BG61186B1 (bg) Цис-2,3,3а,4,5,9в-хексахидро-1н-бензо(е)- индолови производни
WO1993020066A1 (fr) Derives de l'imidazole, du triazole et du tetrazole