JPS6215065B2 - - Google Patents

Info

Publication number: JPS6215065B2
Authority: JP; Japan
Prior art keywords: water; hydroxyornithine; benzoyl; ethanol; hours
Prior art date: 1979-10-01
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

JP12658079A

Other languages

English (en)

Japanese (ja)

Other versions

JPS5651442A (en

Inventor

Haruyuki Oogishi

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Mitsubishi Chemical Corp

Original Assignee

Mitsubishi Chemical Industries Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1979-10-01

Filing date

1979-10-01

Publication date

1987-04-06

1979-10-01 Application filed by Mitsubishi Chemical Industries Ltd filed Critical Mitsubishi Chemical Industries Ltd

1979-10-01 Priority to JP12658079A priority Critical patent/JPS5651442A/ja

1981-05-09 Publication of JPS5651442A publication Critical patent/JPS5651442A/ja

1987-04-06 Publication of JPS6215065B2 publication Critical patent/JPS6215065B2/ja

Status Granted legal-status Critical Current

Links

-1 δ-benzoyl-γ-hydroxyornithine Chemical compound 0.000 claims description 5
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 6
150000001413 amino acids Chemical class 0.000 description 6
210000004027 cell Anatomy 0.000 description 4
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
ZWEHNKRNPOVVGH-UHFFFAOYSA-N 2-Butanone Chemical compound CCC(C)=O ZWEHNKRNPOVVGH-UHFFFAOYSA-N 0.000 description 3
CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 3
OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
IQFYYKKMVGJFEH-XLPZGREQSA-N Thymidine Chemical compound O=C1NC(=O)C(C)=CN1[C@@H]1O[C@H](CO)[C@@H](O)C1 IQFYYKKMVGJFEH-XLPZGREQSA-N 0.000 description 3
238000006243 chemical reaction Methods 0.000 description 3
150000001875 compounds Chemical class 0.000 description 3
IDGUHHHQCWSQLU-UHFFFAOYSA-N ethanol;hydrate Chemical compound O.CCO IDGUHHHQCWSQLU-UHFFFAOYSA-N 0.000 description 3
102000052812 Ornithine decarboxylases Human genes 0.000 description 2
108700005126 Ornithine decarboxylases Proteins 0.000 description 2
JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 description 2
239000012980 RPMI-1640 medium Substances 0.000 description 2
239000003125 aqueous solvent Substances 0.000 description 2
WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 description 2
238000012258 culturing Methods 0.000 description 2
238000000605 extraction Methods 0.000 description 2
239000003112 inhibitor Substances 0.000 description 2
210000004698 lymphocyte Anatomy 0.000 description 2
239000002904 solvent Substances 0.000 description 2
210000000952 spleen Anatomy 0.000 description 2
230000000638 stimulation Effects 0.000 description 2
239000000126 substance Substances 0.000 description 2
ZVDGZUVHJGGWSG-BKLSDQPFSA-N (2s)-2,5-diamino-4-hydroxypentanoic acid Chemical compound NCC(O)C[C@H](N)C(O)=O ZVDGZUVHJGGWSG-BKLSDQPFSA-N 0.000 description 1
JDBLKQWADCRWMX-BYPYZUCNSA-N (2s)-5-amino-2-(hydroxyamino)pentanoic acid Chemical compound NCCC[C@H](NO)C(O)=O JDBLKQWADCRWMX-BYPYZUCNSA-N 0.000 description 1
NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 description 1
239000005711 Benzoic acid Substances 0.000 description 1
DWRXFEITVBNRMK-UHFFFAOYSA-N Beta-D-1-Arabinofuranosylthymine Natural products O=C1NC(=O)C(C)=CN1C1C(O)C(O)C(CO)O1 DWRXFEITVBNRMK-UHFFFAOYSA-N 0.000 description 1
AHLPHDHHMVZTML-BYPYZUCNSA-N L-Ornithine Chemical compound NCCC[C@H](N)C(O)=O AHLPHDHHMVZTML-BYPYZUCNSA-N 0.000 description 1
AHLPHDHHMVZTML-UHFFFAOYSA-N Orn-delta-NH2 Natural products NCCCC(N)C(O)=O AHLPHDHHMVZTML-UHFFFAOYSA-N 0.000 description 1
UTJLXEIPEHZYQJ-UHFFFAOYSA-N Ornithine Natural products OC(=O)C(C)CCCN UTJLXEIPEHZYQJ-UHFFFAOYSA-N 0.000 description 1
238000010521 absorption reaction Methods 0.000 description 1
238000000862 absorption spectrum Methods 0.000 description 1
MHLMRBVCMNDOCW-UHFFFAOYSA-N acetic acid;butan-1-ol;hydrate Chemical compound O.CC(O)=O.CCCCO MHLMRBVCMNDOCW-UHFFFAOYSA-N 0.000 description 1
230000002378 acidificating effect Effects 0.000 description 1
239000002246 antineoplastic agent Substances 0.000 description 1
239000007864 aqueous solution Substances 0.000 description 1
235000010233 benzoic acid Nutrition 0.000 description 1
IQFYYKKMVGJFEH-UHFFFAOYSA-N beta-L-thymidine Natural products O=C1NC(=O)C(C)=CN1C1OC(CO)C(O)C1 IQFYYKKMVGJFEH-UHFFFAOYSA-N 0.000 description 1
230000035584 blastogenesis Effects 0.000 description 1
229920002678 cellulose Polymers 0.000 description 1
239000001913 cellulose Substances 0.000 description 1
229920001429 chelating resin Polymers 0.000 description 1
238000004587 chromatography analysis Methods 0.000 description 1
238000004440 column chromatography Methods 0.000 description 1
229940124558 contraceptive agent Drugs 0.000 description 1
239000003433 contraceptive agent Substances 0.000 description 1
239000013078 crystal Substances 0.000 description 1
238000002425 crystallisation Methods 0.000 description 1
230000008025 crystallization Effects 0.000 description 1
238000000354 decomposition reaction Methods 0.000 description 1
230000000694 effects Effects 0.000 description 1
238000000921 elemental analysis Methods 0.000 description 1
238000010438 heat treatment Methods 0.000 description 1
238000003384 imaging method Methods 0.000 description 1
229960001438 immunostimulant agent Drugs 0.000 description 1
239000003022 immunostimulating agent Substances 0.000 description 1
230000003308 immunostimulating effect Effects 0.000 description 1
238000011534 incubation Methods 0.000 description 1
239000003456 ion exchange resin Substances 0.000 description 1
229920003303 ion-exchange polymer Polymers 0.000 description 1
150000002500 ions Chemical class 0.000 description 1
239000000463 material Substances 0.000 description 1
239000002609 medium Substances 0.000 description 1
238000002844 melting Methods 0.000 description 1
230000008018 melting Effects 0.000 description 1
239000012046 mixed solvent Substances 0.000 description 1
FEMOMIGRRWSMCU-UHFFFAOYSA-N ninhydrin Chemical compound C1=CC=C2C(=O)C(O)(O)C(=O)C2=C1 FEMOMIGRRWSMCU-UHFFFAOYSA-N 0.000 description 1
230000003287 optical effect Effects 0.000 description 1
239000003960 organic solvent Substances 0.000 description 1
229960003104 ornithine Drugs 0.000 description 1
230000000704 physical effect Effects 0.000 description 1
229920001467 poly(styrenesulfonates) Polymers 0.000 description 1
238000000746 purification Methods 0.000 description 1
UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 description 1
238000010992 reflux Methods 0.000 description 1
239000000243 solution Substances 0.000 description 1
229940104230 thymidine Drugs 0.000 description 1
238000005406 washing Methods 0.000 description 1

Landscapes

Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

JP12658079A 1979-10-01 1979-10-01 Ornithine derivative Granted JPS5651442A (en)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
JP12658079A JPS5651442A (en)	1979-10-01	1979-10-01	Ornithine derivative

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP12658079A JPS5651442A (en)	1979-10-01	1979-10-01	Ornithine derivative

Publications (2)

Publication Number	Publication Date
JPS5651442A JPS5651442A (en)	1981-05-09
JPS6215065B2 true JPS6215065B2 (cs)	1987-04-06

Family

ID=14938681

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP12658079A Granted JPS5651442A (en)	1979-10-01	1979-10-01	Ornithine derivative

Country Status (1)

Country	Link
JP (1)	JPS5651442A (cs)

1979
- 1979-10-01 JP JP12658079A patent/JPS5651442A/ja active Granted

Also Published As

Publication number	Publication date
JPS5651442A (en)	1981-05-09

Similar Documents

Publication	Publication Date	Title
US10160780B2 (en)	2018-12-25	Compound extracted from husk and fruit stem of Xanthoceras sobifolia and its extracting method and use thereof
Kashman et al.	1974	The structure determination of two new acylphloroglucinols from Myrtus communis L.
Horton et al.	1967	Anomeric equilibria in derivatives of amino sugars. Nuclear magnetic resonance studies on acetylated amino sugars and specifically deuterated analogs
EP0036663B1 (de)	1984-09-12	Oxiranbuttersäure-Derivate, ihre Herstellung und Verwendung, sowie diese enthaltende Arzneimittel
COXON et al.	1961	Simplified preparation of sophorose (2-O-β-D-glucopyranosyl-D-glucose)
Wolfrom et al.	1958	Synthesis of Amino Sugars by Reduction of Hydrazine Derivatives1
Crombie et al.	1990	Alkaloids of khat (Catha edulis)
US3028430A (en)	1962-04-03	Process for the production of optically active isomers of amphetamine
DE1770161A1 (de)	1971-10-14	Heterocyclische Verbindungen und Verfahren zu ihrer Herstellung
DE3424107C2 (cs)	1990-03-29
JPH0150714B2 (cs)	1989-10-31
SU990230A1 (ru)	1983-01-23	Способ получени стероидных гликозидов,обладающих антимикробным действием
Furneaux	1983	Byproducts in the preparation of penta-O-acetyl-d-hexononitriles from d-galactose and d-glucose
DE2532069A1 (de)	1976-02-05	Acylierte pyrazofurinderivate und verfahren zu ihrer herstellung
Sørensen	1970	o-(α-l-rhamnopyranosyloxy) benzylamine and o-hydroxybenzylamine in Reseda odorata
ONODERA et al.	1962	Synthesis of 2-Amino-2-deoxy-β-D-glucosides via 3, 4, 6-Tri-O-acetyl-2-benzyl-sulfonamido-2-deoxy-α-D-glucopyranosyl Bromide
Watanabe et al.	1970	Nucleosides. LXIX. Synthetic Studies on Nucleoside Antibiotics.(6). Synthses of 1-(4-Amino-2, 3, 4-trideoxy-β-D-erythro-hex-2-enopyranosyl) cytosine and Derivatives related to the Nucleoside Moiety of Blasticidin S
CH409996A (de)	1966-03-31	Verfahren zur Herstellung von substituierten Hydrazinen
JPH02111785A (ja)	1990-04-24	スフインゴ糖脂質
DE1470020A1 (de)	1969-05-29	alpha-Hydrazino-indolyl-(3)-carbonsaeurederivate und Verfahren zu ihrer Herstellung
DE1958383C3 (de)	1974-12-19	Leupeptine, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
CH449006A (de)	1967-12-31	Verfahren zur Herstellung von Fusidinsäure- und Dihydrofusidinsäurederivaten
DE2609533B2 (de)	1980-02-21	Verfahren zur Extraktion von Wirkstoffen, insbesondere von Heterosidestern der Kaffeesäure, sowie diese Verbindungen enthaltende Arzneimittel
DE3688364T2 (de)	1993-11-25	Steroidische Glycolipide als Immunstimulatoren.
JPH0363544B2 (cs)	1991-10-01