JPS6234014B2 - - Google Patents

Description

[Detailed description of the invention]

The present invention relates to a tooth/denture cleaning agent suitable for removing cigarette tar stuck to teeth, dentures, etc. Denture cleaners containing strong alkali as a main ingredient have been commercially available for the purpose of removing cigarette tar and dental plaque. Further, compositions containing organic acids such as citric acid, tartaric acid, malic acid, and their salts in combination have also been found to be effective in removing tar under strongly acidic conditions. However, these tar removers do not necessarily have a high tar removal effect, and even though such strongly alkaline or strongly acidic cleaning agents and compositions can be used for removing tar from dentures, etc. There are problems with using it directly on raw teeth. As a result of various studies conducted by the present inventors to solve the above-mentioned problems, we found that phytic acid or its derivatives are effective against tar adhering to teeth and dentures not only under strongly acidic conditions but also in a wide pH range including the neutral range. The present invention has been completed based on the discovery that the removal of the compound is extremely effective. That is, the present invention provides a cleaning agent for teeth and dentures which contains phytic acid or a derivative thereof as a main component and is highly effective in removing tobacco tar stuck to teeth and dentures. The present invention will be explained in detail below. The phytic acid used in the present invention is a hexaphosphoric acid ester of myo-inositol, and the phytic acid derivatives include phytic acid in which some or all of the hydrogen atoms of the phosphoric acid groups at positions 1 to 6 of phytic acid are replaced with an alkali metal. Alkali metal salts and ammonium salts of phytic acid such as sodium phytate and potassium phytate, as well as those in which some or all of the hydrogen atoms of the phosphoric acid groups at positions 1 to 6 of phytic acid are replaced with alkyl groups, allyl groups, etc. etc. can be used.
Furthermore, phytin present in seeds of plants such as cereals can also be used. These phytic acids and their derivatives are formulated without polyvalent metal salts.
Demonstrates particularly excellent tar removal effect. The blending ratio of these phytic acid and phytic acid derivatives is 0.1 to 50 in terms of phytic acid based on the total weight.
% by weight (hereinafter simply expressed as %), particularly preferably 1 to 20%. The cleaning agent according to the present invention can be prepared by dissolving phytic acid or a derivative thereof in water or other solvent to make it liquid, or adding a binder such as sodium carboxymethyl cellulose, carrageenan, sodium alginate, or vegum, glycerin, or a sorbitol solution. It can be used in the form of a paste by adding a thickening agent such as propylene glycol or polyethylene glycol. In this case, non-polyvalent metal salt powders such as insoluble sodium metaphosphate, anhydrous silicic acid, and plastic powders may be added to these liquids and pastes, and sweeteners such as saccharin sodium, glycyrrhizic acid, and stevioside may be added. Appropriate ingredients such as fragrances and fragrances can also be blended. In addition, phytic acid or its derivatives can be mixed with known ingredients for tablets and powders, such as excipients such as lactose and mannitrate, disintegrants such as corn starch and carboxymethyl cellulose, and binders, to form tablets and powders. It is also possible to take the form of Furthermore, it can be mixed with the non-polyvalent metal salt powder to form a powdered dentifrice. It may also be incorporated into chewing gum and the like. Note that the PH value of the cleaning agent of the present invention is not particularly limited;
Phytic acid or its derivatives exhibit good tar removal effects not only under strongly acidic and strongly alkaline conditions, but also under any pH range from weakly acidic to weakly alkaline. It is preferable that the PH value is in the range of about 4 to 8, and the PH value is adjusted within this range using an appropriate PH adjuster. Examples of PH regulators include inorganic acids such as hydrochloric acid and phosphoric acid; alkali metal hydroxides such as ammonia, sodium hydroxide, and potassium hydroxide; organic acids such as acetic acid, citric acid, tartaric acid, malic acid, and fumaric acid; There are ammonium salts, alkali metal salts, etc., and these can be used alone or in appropriate combinations to adjust the desired pH value. In this case, adding a portion of an organic acid or a salt thereof, particularly sodium citrate, etc., is effective in softening the soapy taste of sodium phytate. Although phytic acid or its alkali metal salts, such as sodium phytate and potassium phytate, have good tar-removal properties, polyvalent metal salts of phytic acid, such as calcium phytate,
Magnesium phytate tends to have a weak tar removal effect, and it is not preferable to use an alkali containing a polyvalent metal such as calcium carbonate, calcium hydroxide, or magnesium hydroxide as a PH regulator; however, in this case, an organic acid or Add that salt. The cleaning agent of the present invention is used depending on its formulation. For example, in the case of a liquid agent, a paste agent, etc., it can be applied to porous plastics, brushes, felt, porous rubber, etc. and impregnated with it to clean teeth and dentures. Wash or
In addition, tablets, powder and granules, etc. are used by dissolving them in water or other solvents and immersing dentures in the solution. In this case, the cleaning agent for dentures can have a low pH and a high amount of phytic acid to achieve tar removal effect in a short time. As mentioned above, the cleaning agent of the present invention swells and removes cigarette tar by applying, contacting, brushing, etc. on teeth, dentures, etc. to which cigarette tar has adhered, and it uses the action of phytic acid or its derivatives. According to
It exhibits an excellent tar removal effect, and shows a remarkable effect in removing tar even when the pH value is around neutrality of 4 to 8, which was impossible with conventional tar removers. Therefore, it can be applied directly to the oral cavity. For the first time, it becomes possible to safely and easily remove tar attached to teeth. Furthermore, since this phytic acid is extracted and manufactured from foods such as grains, it is extremely safe for the human body. In addition, although the aqueous solution of phytic acid or its derivatives itself does not have sufficient action to dissolve tar,
When a tooth with tar adhered to it is immersed in this aqueous solution, a phenomenon in which the tar swells on the tooth surface like a resin is observed, and when this is gently wiped, the tar detaches from the tooth surface. The aqueous solution of the derivative has the effect of breaking down the resin structure of strongly resinized tar, therefore, after applying the cleaning agent of the present invention, by brushing with a regular toothbrush, etc., the tar can be removed more reliably. can do. Hereinafter, the present invention will be specifically explained with reference to Examples. Examples 1 to 6 A cleaning agent having the composition shown in the table below was prepared, and the test object was immersed in the detergent for a certain period of time (6 hours), and then the test object was wiped with paper to determine the degree of tar removal. The judgment results are also listed in the table below. The test object was a denture (made of polymethyl methacrylate) covered with cigarette tar.
were immersed in 5% aqueous ethanol for more than one week, and those from which no tar was removed even when wiped with paper were selected and used for evaluation. Note that the criteria for judgment are as shown below. +++ You can remove tar by just touching it. ++ The tar can be removed just by wiping it lightly. + Wipe hard to remove tar. ± Wipe hard to remove some tar. − The tar cannot be removed even if you wipe it vigorously.

【table】

[Table] As is clear from the table, the detergents containing phytic acid as the main component (Examples 1 to 6) exhibit extremely good tarnishing properties not only in the acidic region with a small PH value, but also in the neutral region with a PH of 4 to 8. It showed a positive effect. However, cleaning agents that do not contain phytic acid (Comparative Examples 1 to 17) have a pH value of 4 to 4.
8 shows almost no tar removal effect or only a weak effect near neutrality, and among these, the most effective citric acid-based tar removal agent (Comparative Example 5,
Even in case 6), the criterion was only "+". Examples 7 to 10 A cleaning agent containing powder having the composition shown in the table below and a cleaning agent containing no powder were prepared, and the teeth were brushed with this twice a day for 30 days using a brush. The tar removal effect was determined. The judgment criteria are as follows. (3 panel members) Judgment criteria (Evaluation was made by photographing and observing the teeth.) ++ Most of the tar was removed. + A large amount of tar was removed. ± Tar was slightly removed. - Almost no tar has been removed.

[Table] As is clear from the table, the cleaning agent containing phytic acid as a main component in which the above powder was present was sufficiently effective. Example 11 50% phytic acid aqueous solution 37.76% 25% sodium hydroxide aqueous solution 33.96 Sodium citrate (dihydrate) 18.52 Water 9.76 Add sodium citrate and water to phytic acid aqueous solution and mix and dissolve, then add sodium hydroxide aqueous solution A neutral cleaning agent with a pH of 6.0 is obtained. Example 12 50 parts of phytic acid powder in 25 parts of 50% phytic acid aqueous solution
1 part, 12 parts of sodium citrate, and 13 parts of talc are added, kneaded, and freeze-dried to obtain a dry product. This is blended into chewing gum of the following composition. Gum base ^* 25.0% Anhydrous glucose 24.0 Finely ground sucrose 30.0 Sorbiturate 10.0 The above dry matter 10.0 Flavor 1.0 Total 100.0 *Gum base composition Natural resin base (ticle) 24% Vinyl acetate 53 Polyisobutylene 10 Butylphthalyl butyl glucorate 4 Span 60 1 Talc 8

Claims (1)

[Scope of Claims] 1. A tooth/denture cleaning agent containing phytic acid or a derivative thereof as a main component. 2. The tooth/denture cleaning agent according to claim 1, wherein the phytic acid equivalent content of phytic acid or its derivative is 0.1 to 50% by weight based on the total weight.