JPS63215639A - Ｂ型肝炎のワクチンの製造方法およびこの方法により得られるワクチン - Google Patents

Ｂ型肝炎のワクチンの製造方法およびこの方法により得られるワクチン

Info

Publication number
JPS63215639A
JPS63215639A JP62313100A JP31310087A JPS63215639A JP S63215639 A JPS63215639 A JP S63215639A JP 62313100 A JP62313100 A JP 62313100A JP 31310087 A JP31310087 A JP 31310087A JP S63215639 A JPS63215639 A JP S63215639A
Authority
JP
Japan
Prior art keywords
particles
hbs antigen
centrifugation
hepatitis
density
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP62313100A
Other languages
English (en)
Japanese (ja)
Inventor
フィリップ　ジャン　アダモヴィッチ
マリー　ノエル　メヴェレック
マルク　ジラール
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PASUTSUULE BUAKUSAN
Original Assignee
PASUTSUULE BUAKUSAN
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PASUTSUULE BUAKUSAN filed Critical PASUTSUULE BUAKUSAN
Publication of JPS63215639A publication Critical patent/JPS63215639A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP62313100A 1986-12-10 1987-12-10 Ｂ型肝炎のワクチンの製造方法およびこの方法により得られるワクチン Pending JPS63215639A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8617265A FR2608052B1 (fr) 1986-12-10 1986-12-10 Procede de preparation d'un vaccin contre l'hepatite b et vaccin obtenu
FR8617265 1986-12-10

Publications (1)

Publication Number Publication Date
JPS63215639A true JPS63215639A (ja) 1988-09-08

Family

ID=9341743

Family Applications (1)

Application Number Title Priority Date Filing Date
JP62313100A Pending JPS63215639A (ja) 1986-12-10 1987-12-10 Ｂ型肝炎のワクチンの製造方法およびこの方法により得られるワクチン

Country Status (11)

Country Link
EP (1) EP0273811B1 (de)
JP (1) JPS63215639A (de)
KR (1) KR880007732A (de)
AT (1) ATE109353T1 (de)
CA (1) CA1306689C (de)
DE (1) DE3750330T2 (de)
DK (1) DK645687A (de)
FR (1) FR2608052B1 (de)
IL (1) IL84729A (de)
NO (1) NO171147C (de)
PT (1) PT86321B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1073604A (zh) * 1991-12-01 1993-06-30 高真南 制备高免疫原性乙型肝炎疫苗的方法
WO1993012815A1 (fr) * 1991-12-27 1993-07-08 Gensci Limited Procede d'obtention d'un antigene de surface recombine de l'hepatite b, antigene et vaccin a base de celui-ci

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1356413A (en) * 1971-09-09 1974-06-12 Pfizer Ltd Method of obtaining purified australia antigen from blood serum
US4088748A (en) * 1976-11-02 1978-05-09 Merck & Co., Inc. Hepatitis B surface antigen
US4162192A (en) * 1978-09-28 1979-07-24 Juridical Foundation Method for purification of HBs antigen
FR2560890B1 (fr) * 1984-03-07 1987-10-16 Grp Genie Genetique Composition utile pour la fabrication de vaccins contenant des particules portant l'antigene de surface du virus de l'hepatite b et le recepteur de l'albumine serique humaine polymerisee, cellules animales capables de produire de telles particules et procede pour leur obtention
US4624918A (en) * 1984-07-09 1986-11-25 Genentech, Inc. Purification process for hepatitis surface antigen and product thereof
US4683294A (en) * 1985-04-03 1987-07-28 Smith Kline Rit, S.A. Process for the extraction and purification of proteins from culture media producing them

Also Published As

Publication number Publication date
NO875142L (no) 1988-06-13
CA1306689C (en) 1992-08-25
ATE109353T1 (de) 1994-08-15
NO171147B (no) 1992-10-26
DE3750330D1 (de) 1994-09-08
NO875142D0 (no) 1987-12-09
DE3750330T2 (de) 1994-11-17
IL84729A (en) 1993-02-21
PT86321A (fr) 1988-01-01
EP0273811B1 (de) 1994-08-03
FR2608052A1 (fr) 1988-06-17
NO171147C (no) 1993-02-03
DK645687A (da) 1988-06-11
DK645687D0 (da) 1987-12-09
KR880007732A (ko) 1988-08-29
PT86321B (pt) 1990-11-07
IL84729A0 (en) 1988-05-31
EP0273811A3 (en) 1988-08-03
FR2608052B1 (fr) 1990-04-13
EP0273811A2 (de) 1988-07-06

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