ATE109353T1 - Verfahren zur herstellung eines impfstoffs gegen hepatitis b. - Google Patents

Verfahren zur herstellung eines impfstoffs gegen hepatitis b.

Info

Publication number
ATE109353T1
ATE109353T1 AT87402743T AT87402743T ATE109353T1 AT E109353 T1 ATE109353 T1 AT E109353T1 AT 87402743 T AT87402743 T AT 87402743T AT 87402743 T AT87402743 T AT 87402743T AT E109353 T1 ATE109353 T1 AT E109353T1
Authority
AT
Austria
Prior art keywords
zonal
subjected
preparation
vaccine against
against hepatitis
Prior art date
Application number
AT87402743T
Other languages
English (en)
Inventor
Philippe Jean Adamowicz
Marie Noelle Mevelec
Marc Girard
Original Assignee
Pasteur Merieux Serums Vacc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pasteur Merieux Serums Vacc filed Critical Pasteur Merieux Serums Vacc
Application granted granted Critical
Publication of ATE109353T1 publication Critical patent/ATE109353T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT87402743T 1986-12-10 1987-12-03 Verfahren zur herstellung eines impfstoffs gegen hepatitis b. ATE109353T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8617265A FR2608052B1 (fr) 1986-12-10 1986-12-10 Procede de preparation d'un vaccin contre l'hepatite b et vaccin obtenu

Publications (1)

Publication Number Publication Date
ATE109353T1 true ATE109353T1 (de) 1994-08-15

Family

ID=9341743

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87402743T ATE109353T1 (de) 1986-12-10 1987-12-03 Verfahren zur herstellung eines impfstoffs gegen hepatitis b.

Country Status (11)

Country Link
EP (1) EP0273811B1 (de)
JP (1) JPS63215639A (de)
KR (1) KR880007732A (de)
AT (1) ATE109353T1 (de)
CA (1) CA1306689C (de)
DE (1) DE3750330T2 (de)
DK (1) DK645687A (de)
FR (1) FR2608052B1 (de)
IL (1) IL84729A (de)
NO (1) NO171147C (de)
PT (1) PT86321B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1073604A (zh) * 1991-12-01 1993-06-30 高真南 制备高免疫原性乙型肝炎疫苗的方法
WO1993012815A1 (fr) * 1991-12-27 1993-07-08 Gensci Limited Procede d'obtention d'un antigene de surface recombine de l'hepatite b, antigene et vaccin a base de celui-ci

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1356413A (en) * 1971-09-09 1974-06-12 Pfizer Ltd Method of obtaining purified australia antigen from blood serum
US4088748A (en) * 1976-11-02 1978-05-09 Merck & Co., Inc. Hepatitis B surface antigen
US4162192A (en) * 1978-09-28 1979-07-24 Juridical Foundation Method for purification of HBs antigen
FR2560890B1 (fr) * 1984-03-07 1987-10-16 Grp Genie Genetique Composition utile pour la fabrication de vaccins contenant des particules portant l'antigene de surface du virus de l'hepatite b et le recepteur de l'albumine serique humaine polymerisee, cellules animales capables de produire de telles particules et procede pour leur obtention
US4624918A (en) * 1984-07-09 1986-11-25 Genentech, Inc. Purification process for hepatitis surface antigen and product thereof
US4683294A (en) * 1985-04-03 1987-07-28 Smith Kline Rit, S.A. Process for the extraction and purification of proteins from culture media producing them

Also Published As

Publication number Publication date
NO875142L (no) 1988-06-13
CA1306689C (en) 1992-08-25
NO171147B (no) 1992-10-26
DE3750330D1 (de) 1994-09-08
NO875142D0 (no) 1987-12-09
DE3750330T2 (de) 1994-11-17
IL84729A (en) 1993-02-21
PT86321A (fr) 1988-01-01
EP0273811B1 (de) 1994-08-03
FR2608052A1 (fr) 1988-06-17
NO171147C (no) 1993-02-03
DK645687A (da) 1988-06-11
DK645687D0 (da) 1987-12-09
KR880007732A (ko) 1988-08-29
PT86321B (pt) 1990-11-07
IL84729A0 (en) 1988-05-31
EP0273811A3 (en) 1988-08-03
JPS63215639A (ja) 1988-09-08
FR2608052B1 (fr) 1990-04-13
EP0273811A2 (de) 1988-07-06

Similar Documents

Publication Publication Date Title
Tytell et al. Inducers of interferon and host resistance. 3. Double-stranded RNA from reovirus type 3 virions (reo 3-RNA).
ATE123225T1 (de) Synthese von menschlichen virusantigenen durch hefe.
MA21911A1 (fr) Procede pour produire une grande proteine de surface modifiee du virus de l'hepatite b .
FI102616B1 (fi) Menetelmä rokotteen valmistamiseksi ihmisen parainfluenssa-viruksen tyyppiä 3 varten ja menetelmässä käytettävä ilmentämisjärjestelmä
AU3473489A (en) Expression of hepatisis b s and pres2proteins in methylotrophic yeasts
Hooks et al. Isolation of a new simian foamy virus from a spider monkey brain culture
EP0231083A3 (en) Purification of pertussis antigens
AU2865084A (en) Virus antigen, preparation process thereof and its utilisation in diagnostic and therapy (vaccine)
DE3750330D1 (de) Verfahren zur Herstellung eines Impfstoffs gegen Hepatitis B.
ATE179428T1 (de) Verfahren zur herstellung von hepatitis antigenen und impfstoffen
GR3029582T3 (en) Method for obtaining recombinant surface antigen of hepatitis B virus (HEP B)
Valenzuela et al. Hepatitis-B vaccine: Characterization of hepatitis-B antigen particles produced in yeast.
KOIKE et al. Production of hepatitis B virus surface antigen particles by the human hepatoma cell line huGK-14 in a serum-free medium
Zuckerman et al. Toward hepatitis B vaccines
DK257887A (da) Fremgangsmaade til fremstilling af hbcag i gaer og plasmid til brug ved udoevelse af fremgangsmaaden
ATE112170T1 (de) Verfahren zur herstellung und reinigung von hepatitis b-impfstoff.
Gerin et al. The molecular biology of hepatitis delta virus: recent advances
Ablashi et al. Extraction of Soluble Antigens of Epstein-Barr Virus, Herpervirus saimiri, and Herpesvirus ateles With the Use of Glycine
Leboulleux et al. Loss of anti-HBc antibodies after HBV infection in immunized Senegalese children
EP0205625A1 (de) Hepatitis-b-virusimpfstoff und dessen herstellung
EP0328123A1 (de) Pre-S-reiches Hepatitis-B-Oberflächenantigen
ATE53235T1 (de) Synthese von menschlichen viralen antigenen mit hilfe von hefe.
Michel et al. Synthesis and secretion of hepatitis-B surface antigen particles in transfected animal cells.
JPH0762033B2 (ja) Ｂ型肝炎ワクチン
Kaufmann et al. Hepatitis B vaccine: Safety study in anti-HBs seronegative human volunteers

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee