JPS63257543A - 病原性増殖組織の破壊法 - Google Patents
病原性増殖組織の破壊法Info
- Publication number
- JPS63257543A JPS63257543A JP63074265A JP7426588A JPS63257543A JP S63257543 A JPS63257543 A JP S63257543A JP 63074265 A JP63074265 A JP 63074265A JP 7426588 A JP7426588 A JP 7426588A JP S63257543 A JPS63257543 A JP S63257543A
- Authority
- JP
- Japan
- Prior art keywords
- metal particles
- lipid
- ultrasound
- shock wave
- pathogenic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 title claims description 31
- 230000001717 pathogenic effect Effects 0.000 title claims 18
- 238000009395 breeding Methods 0.000 title 1
- 230000001488 breeding effect Effects 0.000 title 1
- 239000002923 metal particle Substances 0.000 claims description 63
- 230000035939 shock Effects 0.000 claims description 53
- 150000002632 lipids Chemical class 0.000 claims description 45
- 210000004027 cell Anatomy 0.000 claims description 21
- 239000002502 liposome Substances 0.000 claims description 20
- 238000002604 ultrasonography Methods 0.000 claims description 18
- 238000000926 separation method Methods 0.000 claims description 14
- 239000012528 membrane Substances 0.000 claims description 11
- 230000006378 damage Effects 0.000 claims description 9
- 239000002245 particle Substances 0.000 claims description 7
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 7
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 claims description 6
- 230000002209 hydrophobic effect Effects 0.000 claims description 6
- 229910000510 noble metal Inorganic materials 0.000 claims description 6
- 210000000056 organ Anatomy 0.000 claims description 6
- 230000001575 pathological effect Effects 0.000 claims description 6
- 108090000623 proteins and genes Proteins 0.000 claims description 6
- 102000004169 proteins and genes Human genes 0.000 claims description 6
- 239000000232 Lipid Bilayer Substances 0.000 claims description 5
- 210000000170 cell membrane Anatomy 0.000 claims description 5
- 229910052737 gold Inorganic materials 0.000 claims description 5
- 239000010931 gold Substances 0.000 claims description 5
- 239000000203 mixture Substances 0.000 claims description 5
- 239000004033 plastic Substances 0.000 claims description 5
- 238000002560 therapeutic procedure Methods 0.000 claims description 4
- 239000008346 aqueous phase Substances 0.000 claims description 3
- 238000000576 coating method Methods 0.000 claims description 3
- 210000004369 blood Anatomy 0.000 claims description 2
- 239000008280 blood Substances 0.000 claims description 2
- 239000000969 carrier Substances 0.000 claims description 2
- 238000002512 chemotherapy Methods 0.000 claims description 2
- 239000011248 coating agent Substances 0.000 claims description 2
- 239000007789 gas Substances 0.000 claims description 2
- 238000009217 hyperthermia therapy Methods 0.000 claims description 2
- 239000007924 injection Substances 0.000 claims description 2
- 238000002347 injection Methods 0.000 claims description 2
- 229910052751 metal Inorganic materials 0.000 claims description 2
- 239000002184 metal Substances 0.000 claims description 2
- 230000008520 organization Effects 0.000 claims description 2
- 230000035755 proliferation Effects 0.000 claims description 2
- 239000004094 surface-active agent Substances 0.000 claims description 2
- 230000002062 proliferating effect Effects 0.000 claims 13
- 238000009210 therapy by ultrasound Methods 0.000 claims 5
- 238000002372 labelling Methods 0.000 claims 4
- 230000002950 deficient Effects 0.000 claims 3
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 claims 2
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 claims 1
- 239000013043 chemical agent Substances 0.000 claims 1
- 238000010438 heat treatment Methods 0.000 claims 1
- 239000002596 immunotoxin Substances 0.000 claims 1
- 230000005389 magnetism Effects 0.000 claims 1
- QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 claims 1
- 229910052753 mercury Inorganic materials 0.000 claims 1
- 229910052697 platinum Inorganic materials 0.000 claims 1
- 229910052709 silver Inorganic materials 0.000 claims 1
- 239000004332 silver Substances 0.000 claims 1
- 230000002459 sustained effect Effects 0.000 claims 1
- 239000003053 toxin Substances 0.000 claims 1
- 231100000765 toxin Toxicity 0.000 claims 1
- 108700012359 toxins Proteins 0.000 claims 1
- 210000001519 tissue Anatomy 0.000 description 10
- 206010028980 Neoplasm Diseases 0.000 description 6
- 238000010586 diagram Methods 0.000 description 5
- 230000017531 blood circulation Effects 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 239000010970 precious metal Substances 0.000 description 3
- 238000010322 bone marrow transplantation Methods 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 238000000338 in vitro Methods 0.000 description 2
- 210000004698 lymphocyte Anatomy 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 210000004881 tumor cell Anatomy 0.000 description 2
- 239000002691 unilamellar liposome Substances 0.000 description 2
- 206010019695 Hepatic neoplasm Diseases 0.000 description 1
- 208000000913 Kidney Calculi Diseases 0.000 description 1
- 102000004856 Lectins Human genes 0.000 description 1
- 108090001090 Lectins Proteins 0.000 description 1
- 206010029148 Nephrolithiasis Diseases 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 210000001185 bone marrow Anatomy 0.000 description 1
- 239000003990 capacitor Substances 0.000 description 1
- 210000003855 cell nucleus Anatomy 0.000 description 1
- 239000000084 colloidal system Substances 0.000 description 1
- 230000001143 conditioned effect Effects 0.000 description 1
- 231100000599 cytotoxic agent Toxicity 0.000 description 1
- 239000002619 cytotoxin Substances 0.000 description 1
- 230000008021 deposition Effects 0.000 description 1
- 230000001627 detrimental effect Effects 0.000 description 1
- 235000014113 dietary fatty acids Nutrition 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 238000001493 electron microscopy Methods 0.000 description 1
- 230000003511 endothelial effect Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 229930195729 fatty acid Natural products 0.000 description 1
- 239000000194 fatty acid Substances 0.000 description 1
- 150000004665 fatty acids Chemical group 0.000 description 1
- 238000013467 fragmentation Methods 0.000 description 1
- 238000006062 fragmentation reaction Methods 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 230000001678 irradiating effect Effects 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 239000002523 lectin Substances 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 208000014018 liver neoplasm Diseases 0.000 description 1
- 230000034153 membrane organization Effects 0.000 description 1
- 150000002739 metals Chemical class 0.000 description 1
- 210000003463 organelle Anatomy 0.000 description 1
- 230000003204 osmotic effect Effects 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 230000003389 potentiating effect Effects 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 230000008685 targeting Effects 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
- 238000004804 winding Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N7/00—Ultrasound therapy
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Radiology & Medical Imaging (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Preparation (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Laser Surgery Devices (AREA)
- Surgical Instruments (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19873710371 DE3710371A1 (de) | 1987-03-28 | 1987-03-28 | Zerstoerung von krankhaft veraenderten gewebezellen |
| DE3710371.7 | 1987-03-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS63257543A true JPS63257543A (ja) | 1988-10-25 |
Family
ID=6324282
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP63074265A Pending JPS63257543A (ja) | 1987-03-28 | 1988-03-28 | 病原性増殖組織の破壊法 |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP0284802A3 (fr) |
| JP (1) | JPS63257543A (fr) |
| DE (1) | DE3710371A1 (fr) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008039692A (ja) * | 2006-08-09 | 2008-02-21 | Canon Inc | 標的物質検出材料、及びその製造方法 |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3741201A1 (de) | 1987-12-02 | 1989-06-15 | Schering Ag | Ultraschallarbeitsverfahren und mittel zu dessen durchfuehrung |
| DE3900433A1 (de) * | 1989-01-10 | 1990-07-12 | Schubert Werner | Verfahren und vorrichtung fuer die behandlung von erkrankungen mit ultraschallwellen |
| DE3921808A1 (de) * | 1989-07-03 | 1991-01-17 | Schubert Werner | Vorrichtung zur fokussierten stosswellenbehandlung von tumoren |
| WO2000006244A2 (fr) * | 1998-07-30 | 2000-02-10 | Hainfeld James F | Particules metalliques de chargement dans des vesicules membranaires cellulaires et particule metallique utilisee pour l'imagerie et la therapie |
| DE102007000800A1 (de) * | 2007-10-01 | 2009-04-02 | Beiersdorf Ag | Vorrichtung und Verfahren zur Reduktion der Hautpigmentierung |
| KR101477488B1 (ko) | 2010-01-19 | 2014-12-30 | 보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 | 고주파 충격파를 발생시키기 위한 장치 및 시스템과, 그 사용 방법 |
| AR087170A1 (es) * | 2011-07-15 | 2014-02-26 | Univ Texas | Aparato para generar ondas de choque terapeuticas y sus aplicaciones |
| EP2634246A1 (fr) * | 2012-03-02 | 2013-09-04 | Justus-Liebig-Universität Giessen | Dispositif et procédé d'identification, de séparation et/ou de manipulation spécifique au type de cellule d'au moins une cellule d'un système cellulaire ainsi que de micro-organismes |
| WO2016183307A1 (fr) | 2015-05-12 | 2016-11-17 | Soliton, Inc. | Procédés de traitement de la cellulite et du tissu adipeux sous-cutané |
| WO2017165595A1 (fr) | 2016-03-23 | 2017-09-28 | Soliton, Inc. | Système et procédé de nettoyage cutané par ondes acoustiques pulsées |
| TWI838078B (zh) | 2016-07-21 | 2024-04-01 | 美商席利通公司 | 用於產生醫療脈衝之電容器陣列裝置以及產生醫療脈衝之裝置 |
| US12508043B2 (en) | 2017-01-17 | 2025-12-30 | Soliton, Inc. | Rapid Pulse electrohydraulic (EH) shockwave generator apparatus with improved acoustic wavefronts |
| JP2020508112A (ja) | 2017-02-19 | 2020-03-19 | ソリトン， インコーポレイテッド | 生物学的媒体中の選択的レーザ誘起光学破壊 |
| AU2020254738B2 (en) | 2019-04-03 | 2025-10-30 | Soliton, Inc. | Systems, devices, and methods of treating tissue and cellulite by non-invasive acoustic subcision |
| CN113925572B (zh) * | 2021-11-10 | 2025-07-29 | 上海益超医疗器械有限公司 | 一种手术器械 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2628234A1 (de) * | 1976-06-24 | 1978-01-05 | Wolfgang Joachim Guettner | Hochfrequenz-apparaturen fuer industrielle sterilisation und fuer medizinische therapie und diagnostik |
| US4315514A (en) * | 1980-05-08 | 1982-02-16 | William Drewes | Method and apparatus for selective cell destruction |
| DE3150512A1 (de) * | 1981-12-21 | 1983-06-30 | Battelle-Institut E.V., 6000 Frankfurt | "vorrichtung zur hyperthermiebehandlung von tumoren bei kleintieren" |
| US4501728A (en) * | 1983-01-06 | 1985-02-26 | Technology Unlimited, Inc. | Masking of liposomes from RES recognition |
| US4610241A (en) * | 1984-07-03 | 1986-09-09 | Gordon Robert T | Atherosclerosis treatment method |
| CA1267840A (fr) * | 1984-11-23 | 1990-04-17 | Cary Arnet Presant | Methode de ciblage des tumeurs chez les humains |
| US4652257A (en) * | 1985-03-21 | 1987-03-24 | The United States Of America As Represented By The Secretary Of The Navy | Magnetically-localizable, polymerized lipid vesicles and method of disrupting same |
| DE3517020C1 (de) * | 1985-05-11 | 1986-08-28 | Dornier System Gmbh, 7990 Friedrichshafen | Beruehrungslose Bearbeitung,insbesondere Zerstoerung von kuenstlich hergestellten Werkstoffen,Bauteilen und Strukturteilen |
| US5041581A (en) * | 1985-10-18 | 1991-08-20 | The University Of Texas System Board Of Regents | Hydrophobic cis-platinum complexes efficiently incorporated into liposomes |
| DE3614657A1 (de) * | 1986-04-30 | 1987-11-05 | Dornier Medizintechnik | Pharmaka enthaltende lipidvesikel, verfahren zu ihrer herstellung und einbringung in den koerper eines lebewesens und freisetzung der in den lipidvesikeln enthaltende pharmaka |
-
1987
- 1987-03-28 DE DE19873710371 patent/DE3710371A1/de not_active Withdrawn
-
1988
- 1988-03-02 EP EP88103152A patent/EP0284802A3/fr not_active Withdrawn
- 1988-03-28 JP JP63074265A patent/JPS63257543A/ja active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008039692A (ja) * | 2006-08-09 | 2008-02-21 | Canon Inc | 標的物質検出材料、及びその製造方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| DE3710371A1 (de) | 1988-10-13 |
| EP0284802A3 (fr) | 1988-12-28 |
| EP0284802A2 (fr) | 1988-10-05 |
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