JPS63503241A - 特にhtlv3ウイルスによってひき起こされた感染の実験室的改良診断方法 - Google Patents
特にhtlv3ウイルスによってひき起こされた感染の実験室的改良診断方法Info
- Publication number
- JPS63503241A JPS63503241A JP61506160A JP50616086A JPS63503241A JP S63503241 A JPS63503241 A JP S63503241A JP 61506160 A JP61506160 A JP 61506160A JP 50616086 A JP50616086 A JP 50616086A JP S63503241 A JPS63503241 A JP S63503241A
- Authority
- JP
- Japan
- Prior art keywords
- antigen
- antibodies
- incubation
- antibody
- item
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000002405 diagnostic procedure Methods 0.000 title claims description 6
- 208000015181 infectious disease Diseases 0.000 title description 10
- 241000700605 Viruses Species 0.000 title description 4
- 239000000427 antigen Substances 0.000 claims description 25
- 102000036639 antigens Human genes 0.000 claims description 25
- 108091007433 antigens Proteins 0.000 claims description 25
- 238000000034 method Methods 0.000 claims description 20
- 238000011534 incubation Methods 0.000 claims description 14
- 210000002966 serum Anatomy 0.000 claims description 7
- 238000010828 elution Methods 0.000 claims description 5
- 230000009385 viral infection Effects 0.000 claims description 5
- 238000003745 diagnosis Methods 0.000 claims description 4
- 238000010438 heat treatment Methods 0.000 claims description 4
- 208000036142 Viral infection Diseases 0.000 claims description 3
- 238000001514 detection method Methods 0.000 claims description 3
- 238000003756 stirring Methods 0.000 claims description 3
- 239000003085 diluting agent Substances 0.000 claims description 2
- 238000000926 separation method Methods 0.000 claims description 2
- 239000000126 substance Substances 0.000 claims description 2
- 208000031886 HIV Infections Diseases 0.000 claims 1
- 230000005251 gamma ray Effects 0.000 claims 1
- 208000011580 syndromic disease Diseases 0.000 claims 1
- 241000598436 Human T-cell lymphotropic virus Species 0.000 description 9
- 108060003951 Immunoglobulin Proteins 0.000 description 8
- 102000018358 immunoglobulin Human genes 0.000 description 8
- 210000004369 blood Anatomy 0.000 description 6
- 239000008280 blood Substances 0.000 description 6
- 238000012360 testing method Methods 0.000 description 6
- 102000003992 Peroxidases Human genes 0.000 description 3
- 229940072221 immunoglobulins Drugs 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 230000000405 serological effect Effects 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- 241000283707 Capra Species 0.000 description 2
- 102000004190 Enzymes Human genes 0.000 description 2
- 108090000790 Enzymes Proteins 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 2
- 239000004793 Polystyrene Substances 0.000 description 2
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 2
- 238000011161 development Methods 0.000 description 2
- 108040007629 peroxidase activity proteins Proteins 0.000 description 2
- 229920002223 polystyrene Polymers 0.000 description 2
- 206010029719 Nonspecific reaction Diseases 0.000 description 1
- 108700020962 Peroxidase Proteins 0.000 description 1
- 102000045595 Phosphoprotein Phosphatases Human genes 0.000 description 1
- 108700019535 Phosphoprotein Phosphatases Proteins 0.000 description 1
- 102000004160 Phosphoric Monoester Hydrolases Human genes 0.000 description 1
- 108090000608 Phosphoric Monoester Hydrolases Proteins 0.000 description 1
- 101710172711 Structural protein Proteins 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 230000000890 antigenic effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000000872 buffer Substances 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000007865 diluting Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 210000000987 immune system Anatomy 0.000 description 1
- 229940127121 immunoconjugate Drugs 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 238000003771 laboratory diagnosis Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 239000012071 phase Substances 0.000 description 1
- 239000008363 phosphate buffer Substances 0.000 description 1
- 230000001012 protector Effects 0.000 description 1
- 239000011541 reaction mixture Substances 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000035807 sensation Effects 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000007790 solid phase Substances 0.000 description 1
- 229940043517 specific immunoglobulins Drugs 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56983—Viruses
- G01N33/56988—HIV or HTLV
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Virology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- AIDS & HIV (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Tropical Medicine & Parasitology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT8522941A IT1214642B (it) | 1985-11-21 | 1985-11-21 | Procedimento migliorato per la diagnosi in laboratorio di infezioni in particolare d avirushtlv iii. |
| IT22941A/85 | 1985-11-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS63503241A true JPS63503241A (ja) | 1988-11-24 |
Family
ID=11202122
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP61506160A Pending JPS63503241A (ja) | 1985-11-21 | 1986-11-20 | 特にhtlv3ウイルスによってひき起こされた感染の実験室的改良診断方法 |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0289493A1 (it) |
| JP (1) | JPS63503241A (it) |
| AU (1) | AU6732587A (it) |
| IT (1) | IT1214642B (it) |
| PL (1) | PL262516A1 (it) |
| PT (1) | PT83787B (it) |
| WO (1) | WO1987003375A1 (it) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5268299A (en) * | 1988-04-14 | 1993-12-07 | Eastman Kodak Company | Diluent composition useful in the detection of antibodies in assays |
| US5077198A (en) * | 1988-04-14 | 1991-12-31 | Eastman Kodak Company | Diagnostic kit and method for rapid detection of antibodies |
| US5759774A (en) * | 1988-05-18 | 1998-06-02 | Cobe Laboratories, Inc. | Method of detecting circulating antibody types using dried or lyophilized cells |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5931453A (ja) * | 1982-07-14 | 1984-02-20 | Fujirebio Inc | 梅毒抗体の測定方法 |
| EP0136798A3 (en) * | 1983-08-25 | 1986-02-19 | Biotech Research Laboratories Inc. | Titre plate and assay kit for detection of antibodies in human serum and their production and use |
| IE58321B1 (en) * | 1984-04-23 | 1993-09-08 | Us Health | Isolation of proteins of HTLV-III, serological detection of antibodies to HTLV-III in sera of patients with aids and pre-aids conditions, and detection of HTLV-III infection bi/immuno-assays using HTLV-III infection by immuno-assays using HTLV-III and its proteins |
-
1985
- 1985-11-21 IT IT8522941A patent/IT1214642B/it active
-
1986
- 1986-11-20 AU AU67325/87A patent/AU6732587A/en not_active Abandoned
- 1986-11-20 EP EP86906919A patent/EP0289493A1/en not_active Withdrawn
- 1986-11-20 WO PCT/IT1986/000084 patent/WO1987003375A1/en not_active Ceased
- 1986-11-20 JP JP61506160A patent/JPS63503241A/ja active Pending
- 1986-11-21 PL PL1986262516A patent/PL262516A1/xx unknown
- 1986-11-21 PT PT83787A patent/PT83787B/pt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU6732587A (en) | 1987-07-01 |
| PT83787A (en) | 1986-12-01 |
| PL262516A1 (en) | 1987-12-14 |
| WO1987003375A1 (en) | 1987-06-04 |
| IT1214642B (it) | 1990-01-18 |
| IT8522941A0 (it) | 1985-11-21 |
| EP0289493A1 (en) | 1988-11-09 |
| PT83787B (en) | 1988-02-22 |
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