JPS641476B2 - - Google Patents
Info
- Publication number
- JPS641476B2 JPS641476B2 JP1447981A JP1447981A JPS641476B2 JP S641476 B2 JPS641476 B2 JP S641476B2 JP 1447981 A JP1447981 A JP 1447981A JP 1447981 A JP1447981 A JP 1447981A JP S641476 B2 JPS641476 B2 JP S641476B2
- Authority
- JP
- Japan
- Prior art keywords
- ethyl
- hours
- group
- compound
- hydroxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Landscapes
- Pyrane Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11804980A | 1980-02-04 | 1980-02-04 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS56122375A JPS56122375A (en) | 1981-09-25 |
| JPS641476B2 true JPS641476B2 (de) | 1989-01-11 |
Family
ID=22376230
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP1447981A Granted JPS56122375A (en) | 1980-02-04 | 1981-02-04 | Novel antihypercholesteremic compound* its intermediate and its manufacture |
Country Status (2)
| Country | Link |
|---|---|
| JP (1) | JPS56122375A (de) |
| ZA (1) | ZA81703B (de) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008102563A1 (ja) | 2007-02-23 | 2008-08-28 | Next21 K.K. | 血管攣縮の治療剤又は予防剤 |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0692381B2 (ja) * | 1980-03-31 | 1994-11-16 | 三共株式会社 | Mb−530a誘導体 |
| US4916239A (en) * | 1988-07-19 | 1990-04-10 | Merck & Co., Inc. | Process for the lactonization of mevinic acids and analogs thereof |
| JPH0334975A (ja) * | 1990-04-27 | 1991-02-14 | Sankyo Co Ltd | Ml―236aおよびmb―530a誘導体 |
| HUP0103021A3 (en) * | 1998-12-10 | 2002-04-29 | Kaneka Corp | Process for producing simvastatin derivatives |
| SI1323701T1 (sl) | 2000-09-07 | 2009-12-31 | Kaneka Corp | Postopki za kristalizacijo hidroksikarboksilnih kislin |
| MX2007005129A (es) | 2004-10-27 | 2007-09-11 | Daiichi Sankyo Co Ltd | Compuesto de benceno que tiene 2 o mas sustituyentes. |
| US20090203701A1 (en) | 2006-06-29 | 2009-08-13 | Kowa Co., Ltd | Prophylactic and/or therapeutic agent for rheumatoid arthritis |
| US20100086615A1 (en) | 2007-04-27 | 2010-04-08 | Kyushu University, National University Corporation | Agent for treatment of pulmonary disease |
| WO2011074690A1 (en) | 2009-12-14 | 2011-06-23 | Kyoto University | Pharmaceutical composition for prevention and treatment of amyotrophic lateral sclerosis |
| JP6536871B2 (ja) | 2013-12-02 | 2019-07-03 | 国立大学法人京都大学 | Fgfr3病の予防および治療剤ならびにそのスクリーニング方法 |
| US20210299331A1 (en) | 2018-07-19 | 2021-09-30 | Kyoto University | Pluripotent stem cell-derived plate-shaped cartilage and method for producing the same |
| JP7224001B2 (ja) | 2018-12-21 | 2023-02-17 | 国立大学法人京都大学 | ルブリシン局在軟骨様組織、その製造方法及びそれを含む関節軟骨損傷治療用組成物 |
| US20230172996A1 (en) | 2020-02-21 | 2023-06-08 | Yoshikazu NAKAOKA | Composition for alleviating pulmonary hypertension, method for predicting prognosis of pulmonary hypertension, method for assisting in determining severity of pulmonary hypertension, and method for assisting in diagnosing pulmonary hypertension |
-
1981
- 1981-02-03 ZA ZA00810703A patent/ZA81703B/xx unknown
- 1981-02-04 JP JP1447981A patent/JPS56122375A/ja active Granted
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008102563A1 (ja) | 2007-02-23 | 2008-08-28 | Next21 K.K. | 血管攣縮の治療剤又は予防剤 |
Also Published As
| Publication number | Publication date |
|---|---|
| ZA81703B (en) | 1982-09-29 |
| JPS56122375A (en) | 1981-09-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US4444784A (en) | Antihypercholesterolemic compounds | |
| US4293496A (en) | 6(R)-[2-(8-Hydroxy-2,6-dimethylpolyhydronaphthyl-1)-ethyl]-4(R)-hydroxy-3,4,5,6-tetrahydro-2H-pyran-2-ones | |
| US4450171A (en) | Antihypercholesterolemic compounds | |
| US4282155A (en) | Antihypercholesterolemic compounds | |
| EP0033538B1 (de) | 6(R)-(2-(8'-Acyloxy-2'-methyl-6'-methyl (oder hydrogen)-polyhydronaphthyl-1')-äthyl)-4(R)-hydroxy-3,4,5,6-tetrahydro-2H-pyran-2-one, die Hydroxysäure-Form dieser Pyranone, pharmazeutisch unbedenkliche Salze dieser Säuren, Niederalkylester, durch Phenyl Dimethylamino oder Acetylamino substituierte Niederalkylester dieser Säuren, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische antihypercholesterinämische Zusammensetzung | |
| USRE36520E (en) | HMG-CoA reductase inhibitors | |
| US5116870A (en) | HMG-CoA reductase inhibitors | |
| US4351844A (en) | Hypocholesterolemic hydrogenation products and process of preparation | |
| NO177004B (no) | Analogifremgangsmåte for fremstilling av 7-substituerte derivater av 3,5-dihydroksyhept-6-ynsyre | |
| JPS6366306B2 (de) | ||
| JPS641476B2 (de) | ||
| EP0331250A2 (de) | Antihypercholesterolemisches Mittel | |
| US5099035A (en) | Mevinic acid derivatives useful as antihypercholesterolemic agents and method for preparing same | |
| USRE36481E (en) | HMG-CoA reductase inhibitors | |
| JPH0136471B2 (de) | ||
| US5166364A (en) | Mevinic acid derivatives useful as antihypercholesterolemic agents and method for preparing same | |
| US4665091A (en) | Macrocyclic lactone HMG-CoA reductase inhibitors | |
| US5177104A (en) | 6-α-hydroxy derivatives of mevinic acids | |
| KR850000669B1 (ko) | 항 과콜레스테린 혈증성 화합물의 제법 | |
| EP0306263B1 (de) | Inhibitoren von HMG-CoA-Reduktase | |
| EP0094443A1 (de) | 6(R)-(2-(8(S)(2,2-dimethylbutyryloxy)-2(S),6(S)-dimethyl-1,2,3,4,4a(S),5,6,7,8,8a(S)-decahydronaphthyl-1(S))ethyl)-4(R)-hydroxy-3,4,5,6-tetrahydro-2H-Pyran-2-on, Verfahren zur Herstellung und diese enthaltende pharmazeutische Zusammenstellung | |
| JP2582785B2 (ja) | 新規HMG−CoAレダクタ−ゼ阻害剤 | |
| DE69025817T2 (de) | 3-Keto-HMG-CoA Reduktase-Inhibitoren | |
| US5041562A (en) | 3-keto HMG-CoA reductase inhibitors | |
| CS233718B2 (cs) | Způsob přípravy acyloxypolyhydronaftylderivátů 2H-pyran-2-onu |