JPS6419099A - Bonding compound of lipid a monosaccharide analog with sulfur-containing muramic acid dipeptide derivative - Google Patents

Bonding compound of lipid a monosaccharide analog with sulfur-containing muramic acid dipeptide derivative

Info

Publication number
JPS6419099A
JPS6419099A JP62175767A JP17576787A JPS6419099A JP S6419099 A JPS6419099 A JP S6419099A JP 62175767 A JP62175767 A JP 62175767A JP 17576787 A JP17576787 A JP 17576787A JP S6419099 A JPS6419099 A JP S6419099A
Authority
JP
Japan
Prior art keywords
compound
formula
expressed
lipid
sulfur
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP62175767A
Other languages
Japanese (ja)
Inventor
Akira Hasegawa
Makoto Kiso
Kazuyuki Morihara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Toho Pharmaceutical Industries Co Ltd
Original Assignee
Toho Pharmaceutical Industries Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toho Pharmaceutical Industries Co Ltd filed Critical Toho Pharmaceutical Industries Co Ltd
Priority to JP62175767A priority Critical patent/JPS6419099A/en
Publication of JPS6419099A publication Critical patent/JPS6419099A/en
Pending legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

NEW MATERIAL:A compound obtained by linking a 2-deoxy-4-O-phosphoryl-2-(3- hydroxytetradecanamide)-3-D-[(3-O-alkanoyl)-tetradecanoyl]-D-glucopyra nose derivative expressed by formula I (X is bonding site; l is 8-12) and N-[2-O-(2- acetamide-1-S-sulfhydryl-2,3-dideoxy-6-O-alkanoyl-1-thio-beta-D-glucop yranose-3-yl)-D- lactoyl]-L-alanyl-D-isoglutamine methyl ester expressed by formula II (Y is bonding site; m is 0-22) with a succinoylaminoalkanoyl group expressed by formula III (n is 1-15). USE:An immune-enhancing agent. PREPARATION:For example, a functional group, which does not participate in the following reaction, in a compound expressed by formula II (X is H) is protected and then the partially protected compound is reacted with succinic anhydride and the resultant product is reacted with an aminoalkanoylation product of compound expressed by formula II and then the protecting group of the resultant compound is removed to provide the aimed novel compound.
JP62175767A 1987-07-14 1987-07-14 Bonding compound of lipid a monosaccharide analog with sulfur-containing muramic acid dipeptide derivative Pending JPS6419099A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP62175767A JPS6419099A (en) 1987-07-14 1987-07-14 Bonding compound of lipid a monosaccharide analog with sulfur-containing muramic acid dipeptide derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP62175767A JPS6419099A (en) 1987-07-14 1987-07-14 Bonding compound of lipid a monosaccharide analog with sulfur-containing muramic acid dipeptide derivative

Publications (1)

Publication Number Publication Date
JPS6419099A true JPS6419099A (en) 1989-01-23

Family

ID=16001903

Family Applications (1)

Application Number Title Priority Date Filing Date
JP62175767A Pending JPS6419099A (en) 1987-07-14 1987-07-14 Bonding compound of lipid a monosaccharide analog with sulfur-containing muramic acid dipeptide derivative

Country Status (1)

Country Link
JP (1) JPS6419099A (en)

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