JPS643142A - 2-hylomethyl-3,5-dioxaalkene, its production and acetonylation of active hydrogen compound using same - Google Patents
2-hylomethyl-3,5-dioxaalkene, its production and acetonylation of active hydrogen compound using sameInfo
- Publication number
- JPS643142A JPS643142A JP15696887A JP15696887A JPS643142A JP S643142 A JPS643142 A JP S643142A JP 15696887 A JP15696887 A JP 15696887A JP 15696887 A JP15696887 A JP 15696887A JP S643142 A JPS643142 A JP S643142A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- formula
- dioxaalkene
- acetonylation
- active hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 229910052739 hydrogen Inorganic materials 0.000 title abstract 2
- 239000001257 hydrogen Substances 0.000 title abstract 2
- -1 hydrogen compound Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 abstract 3
- 239000003444 phase transfer catalyst Substances 0.000 abstract 2
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 2
- JKHPOPCIKQQRPU-UHFFFAOYSA-N 3-chloro-2-(methoxymethoxy)prop-1-ene Chemical compound COCOC(=C)CCl JKHPOPCIKQQRPU-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 238000006704 dehydrohalogenation reaction Methods 0.000 abstract 1
- DDXLVDQZPFLQMZ-UHFFFAOYSA-M dodecyl(trimethyl)azanium;chloride Chemical group [Cl-].CCCCCCCCCCCC[N+](C)(C)C DDXLVDQZPFLQMZ-UHFFFAOYSA-M 0.000 abstract 1
- 230000007774 longterm Effects 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 239000008188 pellet Substances 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
Landscapes
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
NEW MATERIAL:The 2-halomethyl-3,5-dioxaalkene of formula I (X is Cl, Br or I; Y is 1W10C alkyl).
EXAMPLE: 2-Chloromethyl-3,5-dioxahexene.
USE: Useful as an electrophilic acetonylation agent for a wide variety of compound containing active hydrogen. The objective compound can be easily produced and purified and has excellent long-term storage stability.
PREPARATION: The objective compound of formula I can be produced by the dehydrohalogenation of a dihalogeno compound of formula II in the presence of a base and a phase-transfer catalyst. The phase-transfer catalyst is preferably dodecyltrimethylammonium chloride, etc., and the base is preferably sodium hydroxide, etc., of the form of powder, pellet or solid. The starting compound of formula II is obtained by reacting an epihalohydrin with a compound of formula III in the presence of a catalyst.
COPYRIGHT: (C)1989,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP15696887A JPS643142A (en) | 1987-06-24 | 1987-06-24 | 2-hylomethyl-3,5-dioxaalkene, its production and acetonylation of active hydrogen compound using same |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP15696887A JPS643142A (en) | 1987-06-24 | 1987-06-24 | 2-hylomethyl-3,5-dioxaalkene, its production and acetonylation of active hydrogen compound using same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH013142A JPH013142A (en) | 1989-01-06 |
| JPS643142A true JPS643142A (en) | 1989-01-06 |
Family
ID=15639258
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP15696887A Pending JPS643142A (en) | 1987-06-24 | 1987-06-24 | 2-hylomethyl-3,5-dioxaalkene, its production and acetonylation of active hydrogen compound using same |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS643142A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1652832A4 (en) * | 2003-08-06 | 2007-05-16 | Sumitomo Chemical Co | HYDROXY PROTECTIVE REAGENT AND METHOD FOR PROTECTING HYDROXY WITH THIS REAGENT |
-
1987
- 1987-06-24 JP JP15696887A patent/JPS643142A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1652832A4 (en) * | 2003-08-06 | 2007-05-16 | Sumitomo Chemical Co | HYDROXY PROTECTIVE REAGENT AND METHOD FOR PROTECTING HYDROXY WITH THIS REAGENT |
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