JPS6440426A - Antitumor agent - Google Patents
Antitumor agentInfo
- Publication number
- JPS6440426A JPS6440426A JP62197395A JP19739587A JPS6440426A JP S6440426 A JPS6440426 A JP S6440426A JP 62197395 A JP62197395 A JP 62197395A JP 19739587 A JP19739587 A JP 19739587A JP S6440426 A JPS6440426 A JP S6440426A
- Authority
- JP
- Japan
- Prior art keywords
- salt
- antitumor agent
- lower alkyl
- membered
- ointment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000002246 antineoplastic agent Substances 0.000 title abstract 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- OFOBLEOULBTSOW-UHFFFAOYSA-N Propanedioic acid Natural products OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 abstract 1
- FZEYVTFCMJSGMP-UHFFFAOYSA-N acridone Chemical class C1=CC=C2C(=O)C3=CC=CC=C3NC2=C1 FZEYVTFCMJSGMP-UHFFFAOYSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 125000001589 carboacyl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000006071 cream Substances 0.000 abstract 1
- 239000002552 dosage form Substances 0.000 abstract 1
- 239000000499 gel Substances 0.000 abstract 1
- 239000008187 granular material Substances 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 abstract 1
- 239000011976 maleic acid Substances 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 239000002674 ointment Substances 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
- 239000003826 tablet Substances 0.000 abstract 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 abstract 1
Landscapes
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Abstract
PURPOSE:To obtain an antitumor agent containing acridone alkaloid or a salt thereof as an active ingredient. CONSTITUTION:A compound shown by the formula (R<1> is H or lower alkanoyl; R<2>-R<8> are H, lower alkyl, hydroxy, lower alkoxy, lower alkanoyloxy or R<2> and R<3> or R<3> and R<4> may be bonded to form 5-membered or 6-membered oxygen-containing heterocyclic ring; R<9> is H or lower alkyl) or a salt (e.g. hydrochloric acid or maleic acid) as a main component is blended with a conventional drug additive and pharmaceutically manufactured by a conventional procedure to give the aimed substance. The material can be prepared into a dosage form such as tablet, capsule, granule, solution, ointment, gel, suspension or cream. A dose is 0.1-2,000mg daily and administered once - dividedly several time.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP62197395A JPS6440426A (en) | 1987-08-07 | 1987-08-07 | Antitumor agent |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP62197395A JPS6440426A (en) | 1987-08-07 | 1987-08-07 | Antitumor agent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS6440426A true JPS6440426A (en) | 1989-02-10 |
Family
ID=16373792
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP62197395A Pending JPS6440426A (en) | 1987-08-07 | 1987-08-07 | Antitumor agent |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS6440426A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1990014008A1 (en) * | 1989-05-25 | 1990-11-29 | Sloan-Kettering Institute For Cancer Research | Methods and compositions for inhibiting tumor cell growth |
| WO1997012871A1 (en) * | 1995-03-31 | 1997-04-10 | Eisai Co., Ltd. | Acridone derivative |
-
1987
- 1987-08-07 JP JP62197395A patent/JPS6440426A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1990014008A1 (en) * | 1989-05-25 | 1990-11-29 | Sloan-Kettering Institute For Cancer Research | Methods and compositions for inhibiting tumor cell growth |
| WO1997012871A1 (en) * | 1995-03-31 | 1997-04-10 | Eisai Co., Ltd. | Acridone derivative |
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