JPS6447747A - Method for collecting 7-dimethylamino-6-demethyl-6-deoxytetracycline - Google Patents

Method for collecting 7-dimethylamino-6-demethyl-6-deoxytetracycline

Info

Publication number
JPS6447747A
JPS6447747A JP20354087A JP20354087A JPS6447747A JP S6447747 A JPS6447747 A JP S6447747A JP 20354087 A JP20354087 A JP 20354087A JP 20354087 A JP20354087 A JP 20354087A JP S6447747 A JPS6447747 A JP S6447747A
Authority
JP
Japan
Prior art keywords
minocycline
aqueous solution
deoxytetracycline
demethyl
dimethylamino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP20354087A
Other languages
Japanese (ja)
Other versions
JPH0737434B2 (en
Inventor
Hiroaki Ono
Ryoichi Hasegawa
Kazuaki Sano
Yoshinori Saito
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nippon Kayaku Co Ltd
Original Assignee
Nippon Kayaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Kayaku Co Ltd filed Critical Nippon Kayaku Co Ltd
Priority to JP20354087A priority Critical patent/JPH0737434B2/en
Priority to US07/222,886 priority patent/US4918208A/en
Publication of JPS6447747A publication Critical patent/JPS6447747A/en
Priority to US07/758,274 priority patent/US5202449A/en
Publication of JPH0737434B2 publication Critical patent/JPH0737434B2/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PURPOSE:To collect tetracycline based antibiotics without requiring special reagent and organic solvent in high purity and yield by subjecting a minocycline- containing aqueous solution to one absorption-elution treatment by a nonpolar and high-porous polymer. CONSTITUTION:An aqueous solution containing 7-dimethylamino-6-demethyl-6- deoxytetracycline (hereafter described as minocycline) is absorbed using a nonpolar and high-porous polymer as an absorbent at ambient temperature. Then minocycline is eluted with a polar organic solvent (e.g. methanol) mixable with water. The absorbent is used at 10-100 times amount (cc/g) based on an amount of minocycline in minocycline-containing aqueous solution. The minocycline-containing aqueous solution is preferably absorbed after adjusting pH to 3-9 by adding water thereto.
JP20354087A 1987-07-28 1987-08-18 Method for collecting 7-dimethylamino-6-demethyl-6-deoxytetracycline Expired - Fee Related JPH0737434B2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP20354087A JPH0737434B2 (en) 1987-08-18 1987-08-18 Method for collecting 7-dimethylamino-6-demethyl-6-deoxytetracycline
US07/222,886 US4918208A (en) 1987-07-28 1988-07-22 Process for producing 7-dimethylamino-6-demethyl-6-deoxytetracycline
US07/758,274 US5202449A (en) 1987-07-28 1991-08-27 Process for purifying 7-dimethylamino-6-demethyl-6-deoxytetracycline

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP20354087A JPH0737434B2 (en) 1987-08-18 1987-08-18 Method for collecting 7-dimethylamino-6-demethyl-6-deoxytetracycline

Publications (2)

Publication Number Publication Date
JPS6447747A true JPS6447747A (en) 1989-02-22
JPH0737434B2 JPH0737434B2 (en) 1995-04-26

Family

ID=16475837

Family Applications (1)

Application Number Title Priority Date Filing Date
JP20354087A Expired - Fee Related JPH0737434B2 (en) 1987-07-28 1987-08-18 Method for collecting 7-dimethylamino-6-demethyl-6-deoxytetracycline

Country Status (1)

Country Link
JP (1) JPH0737434B2 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008293931A (en) * 2007-05-28 2008-12-04 Panasonic Electric Works Co Ltd Opening / closing surface guide method and lighting apparatus used therefor
JP2018506539A (en) * 2015-02-13 2018-03-08 ホビオネ サイエンティア リミテッド Novel polymorph of minocycline base and process for producing the same

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008293931A (en) * 2007-05-28 2008-12-04 Panasonic Electric Works Co Ltd Opening / closing surface guide method and lighting apparatus used therefor
JP2018506539A (en) * 2015-02-13 2018-03-08 ホビオネ サイエンティア リミテッド Novel polymorph of minocycline base and process for producing the same

Also Published As

Publication number Publication date
JPH0737434B2 (en) 1995-04-26

Similar Documents

Publication Publication Date Title
MX169466B (en) PROCEDURE FOR THE CONTINUOUS OBTAINING OF MONOISOCIANATES OR POLYISOCYANATES
DE3665540D1 (en) Process for the decontamination of soil by means of micro-organisms
PH16533A (en) Method for producing ethanol in high concentration by using immobilized microorganis
ES460385A1 (en) Process for converting cis-hexahydrodibenzo{8 b,d{9 pyran-9-ones to trans-hexahydrodibenzo{8 b,d{9 -pyran-9-ones
ES2083542T3 (en) DERIVED FROM TIENIL-2-GLICIDIC ACID, ITS PREPARATION PROCEDURE, AND ITS USE AS A SYNTHESIS INTERMEDIARY.
ATE16406T1 (en) PROCESS FOR THE PRODUCTION OF ISOMALTULOSE (6-O-ALPHA-D-GLUCO-PYRANOSIDO-D-FRUCTOSE) USING IMMOBILIZED BACTERIAL CELLS.
JPS57167009A (en) Dimming body
JPS6447747A (en) Method for collecting 7-dimethylamino-6-demethyl-6-deoxytetracycline
JPS5338690A (en) Isolation of co-enzyme q
JPS5389259A (en) Process for biologically denitrification of organic waste water
EP0331745A4 (en) Ferrocene derivatives, surfactants containing same, and process for producing thin organic film
JPS5424457A (en) Process for swelling treatment of organic sludge
JPS5223020A (en) Process for preparation of fluorocompound containing oxygen
ES486851A1 (en) Process for the production of ursodesoxycholic acid
JPS5581794A (en) Recovery method for methane gas
JPS5769667A (en) Electrode
JPS5247982A (en) Method for low temperature immobilization of yeast or microbial cells
JPS5436300A (en) Collection of protein
JPS5249085A (en) Method of decomposing organic sample
DE3569103D1 (en) Process for the preparation of monochlorohydroquinones
JPS55147260A (en) Photosensitized production of viologen cation radical
JPS53139354A (en) Method of treating wast water by microorganism film
ES8604978A1 (en) A process for isolating levamisole from tetramisole.
JPS5422445A (en) Method of treating article
DE3565248D1 (en) Method and apparatus for preparing high-concentration alkali

Legal Events

Date Code Title Description
LAPS Cancellation because of no payment of annual fees