JPS6469A - Novel prolinal derivative, production thereof and drug for alleviating amnesia containing said derivative - Google Patents

Novel prolinal derivative, production thereof and drug for alleviating amnesia containing said derivative

Info

Publication number: JPS6469A
Authority: JP; Japan
Prior art keywords: derivative; formula; amnesia; alleviating; drug
Prior art date: 1987-02-04
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

JP63022814A

Other languages

English (en)

Other versions

JP2528343B2 (ja

JPH0169A (ja

Inventor

Masaaki Toda

Shuichi Ouchida

Hiroyuki Ono

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Ono Pharmaceutical Co Ltd

Original Assignee

Ono Pharmaceutical Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-02-04

Filing date

1988-02-04

Publication date

1989-01-05

1988-02-04 Application filed by Ono Pharmaceutical Co Ltd filed Critical Ono Pharmaceutical Co Ltd

1988-02-04 Priority to JP63022814A priority Critical patent/JP2528343B2/ja

1989-01-05 Publication of JPS6469A publication Critical patent/JPS6469A/ja

1989-01-05 Publication of JPH0169A publication Critical patent/JPH0169A/ja

1996-08-28 Application granted granted Critical

1996-08-28 Publication of JP2528343B2 publication Critical patent/JP2528343B2/ja

2011-08-28 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Links

208000000044 Amnesia Diseases 0.000 title abstract 2
208000031091 Amnestic disease Diseases 0.000 title abstract 2
230000006986 amnesia Effects 0.000 title abstract 2
AGRIQBHIKABLPJ-UHFFFAOYSA-N 1-Pyrrolidinecarboxaldehyde Chemical class O=CN1CCCC1 AGRIQBHIKABLPJ-UHFFFAOYSA-N 0.000 title 1
239000003814 drug Substances 0.000 title 1
229940079593 drug Drugs 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 2
OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
102000056251 Prolyl Oligopeptidases Human genes 0.000 abstract 1
101710178372 Prolyl endopeptidase Proteins 0.000 abstract 1
HVVNJUAVDAZWCB-YFKPBYRVSA-N [(2s)-pyrrolidin-2-yl]methanol Chemical class OC[C@@H]1CCCN1 HVVNJUAVDAZWCB-YFKPBYRVSA-N 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
125000002947 alkylene group Chemical group 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
125000000623 heterocyclic group Chemical group 0.000 abstract 1
125000001183 hydrocarbyl group Chemical group 0.000 abstract 1
230000002401 inhibitory effect Effects 0.000 abstract 1
239000000463 material Substances 0.000 abstract 1
239000003960 organic solvent Substances 0.000 abstract 1
239000007800 oxidant agent Substances 0.000 abstract 1
229930195734 saturated hydrocarbon Natural products 0.000 abstract 1
125000001424 substituent group Chemical group 0.000 abstract 1

Landscapes

Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyrrole Compounds (AREA)

JP63022814A 1987-02-04 1988-02-04 新規なプロリナ―ル誘導体 Expired - Lifetime JP2528343B2 (ja)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
JP63022814A JP2528343B2 (ja)	1987-02-04	1988-02-04	新規なプロリナ―ル誘導体

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
JP62-22407		1987-02-04
JP2240787		1987-02-04
JP63022814A JP2528343B2 (ja)	1987-02-04	1988-02-04	新規なプロリナ―ル誘導体

Publications (3)

Publication Number	Publication Date
JPS6469A true JPS6469A (en)	1989-01-05
JPH0169A JPH0169A (ja)	1989-01-05
JP2528343B2 JP2528343B2 (ja)	1996-08-28

Family

ID=26359622

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP63022814A Expired - Lifetime JP2528343B2 (ja)	1987-02-04	1988-02-04	新規なプロリナ―ル誘導体

Country Status (1)

Country	Link
JP (1)	JP2528343B2 (ja)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2004098591A2 (en)	2003-05-05	2004-11-18	Probiodrug Ag	Inhibitors of glutaminyl cyclase and their use in the treatment of neurological diseases
WO2011029920A1 (en)	2009-09-11	2011-03-17	Probiodrug Ag	Heterocylcic derivatives as inhibitors of glutaminyl cyclase
EP2338490A2 (en)	2003-11-03	2011-06-29	Probiodrug AG	Combinations Useful for the Treatment of Neuronal Disorders
WO2011107530A2 (en)	2010-03-03	2011-09-09	Probiodrug Ag	Novel inhibitors
EP2481408A2 (en)	2007-03-01	2012-08-01	Probiodrug AG	New use of glutaminyl cyclase inhibitors
EP2865670A1 (en)	2007-04-18	2015-04-29	Probiodrug AG	Thiourea derivatives as glutaminyl cyclase inhibitors

1988
- 1988-02-04 JP JP63022814A patent/JP2528343B2/ja not_active Expired - Lifetime

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2004098591A2 (en)	2003-05-05	2004-11-18	Probiodrug Ag	Inhibitors of glutaminyl cyclase and their use in the treatment of neurological diseases
EP2338490A2 (en)	2003-11-03	2011-06-29	Probiodrug AG	Combinations Useful for the Treatment of Neuronal Disorders
EP2481408A2 (en)	2007-03-01	2012-08-01	Probiodrug AG	New use of glutaminyl cyclase inhibitors
EP2865670A1 (en)	2007-04-18	2015-04-29	Probiodrug AG	Thiourea derivatives as glutaminyl cyclase inhibitors
WO2011029920A1 (en)	2009-09-11	2011-03-17	Probiodrug Ag	Heterocylcic derivatives as inhibitors of glutaminyl cyclase
WO2011107530A2 (en)	2010-03-03	2011-09-09	Probiodrug Ag	Novel inhibitors

Also Published As

Publication number	Publication date
JP2528343B2 (ja)	1996-08-28

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