JPS6470428A - Compound and manufacture - Google Patents

Compound and manufacture

Info

Publication number: JPS6470428A
Authority: JP; Japan
Prior art keywords: compounds; manufacture; compound; novel; sulfone
Prior art date: 1980-01-02
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

JP63151360A

Other languages

English (en)

Other versions

JPH0349899B2 (ja

Inventor

Saakaa Aira

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Warner Lambert Co LLC

Original Assignee

Warner Lambert Co LLC

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1980-01-02

Filing date

1988-06-21

Publication date

1989-03-15

1988-06-21 Application filed by Warner Lambert Co LLC filed Critical Warner Lambert Co LLC

1989-03-15 Publication of JPS6470428A publication Critical patent/JPS6470428A/ja

1991-07-31 Publication of JPH0349899B2 publication Critical patent/JPH0349899B2/ja

Status Granted legal-status Critical Current

Links

150000001875 compounds Chemical class 0.000 title abstract 3
238000004519 manufacturing process Methods 0.000 title abstract 2
NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
125000000732 arylene group Chemical group 0.000 abstract 1
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1
229910052760 oxygen Inorganic materials 0.000 abstract 1
239000001301 oxygen Substances 0.000 abstract 1
125000001424 substituent group Chemical group 0.000 abstract 1
150000003457 sulfones Chemical class 0.000 abstract 1
150000003462 sulfoxides Chemical class 0.000 abstract 1
229910052717 sulfur Inorganic materials 0.000 abstract 1
239000011593 sulfur Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
- C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
- C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C62/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C62/30—Unsaturated compounds
- C07C62/34—Unsaturated compounds containing ether groups, groups, groups, or groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Hematology (AREA)
Obesity (AREA)
Diabetes (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

JP63151360A 1980-01-02 1988-06-21 Compound and manufacture Granted JPS6470428A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/108,978 US4351950A (en)	1980-01-02	1980-01-02	Anti-arteriosclerotic agents

Publications (2)

Publication Number	Publication Date
JPS6470428A true JPS6470428A (en)	1989-03-15
JPH0349899B2 JPH0349899B2 (ja)	1991-07-31

Family

ID=22325154

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
JP18514380A Granted JPS56113722A (en)	1980-01-02	1980-12-27	Antiatherosclerotic compound
JP63151360A Granted JPS6470428A (en)	1980-01-02	1988-06-21	Compound and manufacture

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
JP18514380A Granted JPS56113722A (en)	1980-01-02	1980-12-27	Antiatherosclerotic compound

Country Status (6)

Country	Link
US (1)	US4351950A (ja)
EP (1)	EP0032063B1 (ja)
JP (2)	JPS56113722A (ja)
AT (1)	ATE6586T1 (ja)
DE (1)	DE3067072D1 (ja)
HK (1)	HK69087A (ja)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3125059A1 (de) *	1981-06-26	1983-01-05	Bayer Ag, 5090 Leverkusen	Dioxybenzoletherderivate, diese enthaltende arzneimittel, verfahren zu ihrer herstellung und ihre verwendung
IT1170214B (it) *	1983-09-12	1987-06-03	Crinos Industria Farmaco	Composizione farmaceutica per la cura delle arteriopatie periferiche
US4603142A (en) *	1984-06-01	1986-07-29	Wisconsin Alumni Research Foundation	Cholesterol lowering method of use
EP0175188A1 (de) *	1984-09-11	1986-03-26	Nihon Tokushu Noyaku Seizo K.K.	Carbamoylimidazol-Derivate
US4876279A (en) *	1986-05-05	1989-10-24	Merck & Co., Inc.	Antihypercholesterolemic compounds
US4847306A (en) *	1986-05-05	1989-07-11	Merck & Co., Inc.	Antihypercholesterolemic compounds
EP0380633A4 (en) *	1988-07-11	1990-12-05	East Tennessee State University	Arteriosclerosis prognostication procedure and therapeutic method
US4937371A (en) *	1989-02-21	1990-06-26	Hoffmann-La Roche Inc.	Dihydroxynaphthalene derivatives
CA2074537A1 (en) *	1991-07-29	1993-01-30	Bruce E. Witzel	Catechol type non-steroidal drugs as 5-alpha reductase inhibitors
FR2738817B1 (fr) *	1995-09-14	1997-10-17	Adir	Nouveaux acides et esters 2,2-dimethyl-omega-phenoxy alcanoiques substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
IL155246A0 (en)	2000-10-11	2003-11-23	Esperion Therapeutics Inc	Sulfoxide and bis-sulfoxide compounds and compositions for cholesterol management and related uses
AU2002211666A1 (en)	2000-10-11	2002-04-22	Esperion Therapeutics, Inc.	Sulfide and disulfide compounds and compositions for cholesterol management and related uses
US6713507B2 (en) *	2000-10-11	2004-03-30	Esperion Therapeutics, Inc.	Ether compounds and compositions for cholesterol management and related uses
US7816385B2 (en)	2002-12-20	2010-10-19	High Point Pharmaceuticals, Llc	Dimeric dicarboxylic acid derivatives, their preparation and use
AU2003287912A1 (en) *	2002-12-20	2004-07-14	Novo Nordisk A/S	Dicarboxylic acid derivatives as ppar-agonists
AU2003300438A1 (en) *	2003-12-24	2005-08-03	Esperion Therapeutics, Inc.	Ether compounds and compositions for cholesterol management and related uses
WO2005068418A1 (en) *	2003-12-24	2005-07-28	Esperion Therapeutics, Inc.	Sulfide and disulfide compounds and compositions for cholesterol management and related uses
US7846878B2 (en)	2007-07-17	2010-12-07	Halliburton Energy Services, Inc.	Friction reducer performance in water containing multivalent ions
WO2023102364A1 (en) *	2021-12-02	2023-06-08	Ecole Polytechnique Federale De Lausanne (Epfl)	Antiviral compounds, compositions and uses thereof
JP7266139B1 (ja) *	2022-07-22	2023-04-27	本州化学工業株式会社	芳香族ビスエーテル化合物の製造方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BE627791A (ja) *	1962-02-10
GB1129175A (en) *	1966-06-23	1968-10-02	Pfizer Ltd	4,4'-substituted biphenyls
US3674836A (en) *	1968-05-21	1972-07-04	Parke Davis & Co	2,2-dimethyl-{11 -aryloxy-alkanoic acids and salts and esters thereof
FR2060088B1 (ja) *	1969-08-08	1974-08-30	Orsymonde
US3824293A (en) *	1972-11-07	1974-07-16	Union Carbide Corp	Bisthioethers
FR2331336A1 (fr) *	1975-11-14	1977-06-10	Rolland Sa A	Acides oxy-4,4' bis(phenoxy-2 alcanocarboxyliques), leurs derives et leur application comme medicament

1980
- 1980-01-02 US US06/108,978 patent/US4351950A/en not_active Expired - Lifetime
- 1980-12-27 JP JP18514380A patent/JPS56113722A/ja active Granted
- 1980-12-30 DE DE8080304749T patent/DE3067072D1/de not_active Expired
- 1980-12-30 EP EP80304749A patent/EP0032063B1/en not_active Expired
- 1980-12-30 AT AT80304749T patent/ATE6586T1/de not_active IP Right Cessation
1987
- 1987-09-24 HK HK690/87A patent/HK69087A/en not_active IP Right Cessation
1988
- 1988-06-21 JP JP63151360A patent/JPS6470428A/ja active Granted

Also Published As

Publication number	Publication date
JPS56113722A (en)	1981-09-07
JPH0132811B2 (ja)	1989-07-10
HK69087A (en)	1987-10-02
DE3067072D1 (en)	1984-04-19
EP0032063B1 (en)	1984-03-14
JPH0349899B2 (ja)	1991-07-31
EP0032063A3 (en)	1981-11-18
EP0032063A2 (en)	1981-07-15
ATE6586T1 (de)	1984-03-15
US4351950A (en)	1982-09-28

Publication	Publication Date	Title
DE3067072D1 (en)	1984-04-19	Novel substituted arylene compounds and processes for their production
IT8125464A0 (it)	1981-12-04	Derivati dell'1-sulfo-2-ossoazetidina, loro produzione ed impiego.
FR2564469B1 (fr)	1988-06-10	Complexes de sulfure de polyarylene, procedes de production et utilisations de ceux-ci
ATE22104T1 (de)	1986-09-15	Herstellung von pyrrolo-(3,4-c)-pyrrolen.
ATE107635T1 (de)	1994-07-15	Arylendiamin-substituierte pyrimidine.
DE3585111D1 (de)	1992-02-20	Spiro-oxazinverbindungen, ihre herstellung und photochromischer geformter artikel.
IT1164634B (it)	1987-04-15	Derivati cefalosporinici e composizioni antibatteriche che li contengono,nonche' procedimento per la loro produzione
ATE8461T1 (de)	1984-08-15	Gangliosidderivate, ihre herstellung und ihre verwendung.
PH19857A (en)	1986-07-22	Antiinflammatory 17, 17, bis (substituted thio) androstents
ATE64T1 (de)	1981-05-15	Substituierte cyanamide, verfahren zu ihrer herstellung und ihre verwendung als fungizide.
DE3162089D1 (de)	1984-03-08	Antiinflammatory 4,5-diaryl-alpha-(polyfluoroalkyl)-1h-pyrrole-2-methanamines
IT8322080A0 (it)	1983-07-14	Derivati del n-fenilpirazolo utili come erbicidi.
BG40147A3 (bg)	1986-10-15	Метод за получаване на хетероциклични съединения
DE68914711D1 (de)	1994-05-26	1,4-Disubstituierte-2,3,4,6-tetrahydroxy-1,4-diphosphorinan und ihre Oxide oder Sulfides.
IT8025261A0 (it)	1980-10-09	Procedimento per la produzione di teatrafluoruro di zolfo.
IT1122745B (it)	1986-04-23	Procedimento per la produzione di diciclopentilen parentesi quadra aperta 2,2'-bis(4-alchil-6-t-butilfenoli)parentesi quadra chiusa
IT8148412A0 (it)	1981-05-07	Composti dis-o poliazoici esenti da gruppi solfo e loro complessi metalliferi 2.1
DE3381839D1 (de)	1990-10-04	Triazinverbindungen, ihre herstellung und ihre verwendung.
ES505310A0 (es)	1982-12-01	Metodo de obtener nuevos compuestos citostaticos del tipo de la vinblastina y similares.
IT8125742A0 (it)	1981-12-21	1,4-bisostituiti e processo per la derivati piperazinici loro preparazione.
DE3381313D1 (de)	1990-04-19	Dihydropyridinderivate, deren herstellung und verwendung.
ES507704A0 (es)	1982-09-01	Nuevo procedimiento de fabricacion de derivados de 5,6,7,7atetrahidro-4h-tieno(3,2-c)piridin-2-ona .
IT1148012B (it)	1986-11-26	Derivati isossazolici di composti tipo 9alfa 11alfa-epossi-immino-9,11,15-trideossi-pgf
PL202246A1 (pl)	1978-07-31	Sposob wytwarzania 1,1-dwuchlorowco-4-metylopentadienu-1,3
FI871307A0 (fi)	1987-03-25	Foerfarande foer framstaellning av ett nytt, terapeutiskt anvaendbart 1,2-dihydro-4h-pyrrolo-/1,2-c/ tiazin-1,3.