JPS6475475A - Novel substituted diphenylthizole derivative - Google Patents

Novel substituted diphenylthizole derivative

Info

Publication number: JPS6475475A
Authority: JP; Japan
Prior art keywords: compound shown; formula; drug; diphenylthizole; derivative
Prior art date: 1987-09-14
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

JP23007487A

Other languages

English (en)

Other versions

JPH0753666B2 (ja

Inventor

Masayoshi Tsuji

Toshitaka Inoue

Koichi Ikesue

Masaru Saida

Yasuaki Taniguchi

Yoshiki Deguchi

Kanji Noda

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Hisamitsu Pharmaceutical Co Inc

Original Assignee

Hisamitsu Pharmaceutical Co Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-09-14

Filing date

1987-09-14

Publication date

1989-03-22

1987-09-14 Application filed by Hisamitsu Pharmaceutical Co Inc filed Critical Hisamitsu Pharmaceutical Co Inc

1987-09-14 Priority to JP62230074A priority Critical patent/JPH0753666B2/ja

1989-03-22 Publication of JPS6475475A publication Critical patent/JPS6475475A/ja

1995-06-07 Publication of JPH0753666B2 publication Critical patent/JPH0753666B2/ja

2010-06-07 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Links

150000001875 compounds Chemical class 0.000 abstract 4
-1 (substituted)phenoxy Chemical group 0.000 abstract 2
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
125000003545 alkoxy group Chemical group 0.000 abstract 2
239000003814 drug Substances 0.000 abstract 2
229940079593 drug Drugs 0.000 abstract 2
229910052736 halogen Inorganic materials 0.000 abstract 2
150000002367 halogens Chemical class 0.000 abstract 2
RAIPHJJURHTUIC-UHFFFAOYSA-N 1,3-thiazol-2-amine Chemical compound NC1=NC=CS1 RAIPHJJURHTUIC-UHFFFAOYSA-N 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
239000004480 active ingredient Substances 0.000 abstract 1
125000002252 acyl group Chemical group 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
229950003476 aminothiazole Drugs 0.000 abstract 1
230000000202 analgesic effect Effects 0.000 abstract 1
239000002260 anti-inflammatory agent Substances 0.000 abstract 1
229940124599 anti-inflammatory drug Drugs 0.000 abstract 1
230000001754 anti-pyretic effect Effects 0.000 abstract 1
230000003356 anti-rheumatic effect Effects 0.000 abstract 1
239000002221 antipyretic Substances 0.000 abstract 1
239000003435 antirheumatic agent Substances 0.000 abstract 1
125000000753 cycloalkyl group Chemical group 0.000 abstract 1
125000000623 heterocyclic group Chemical group 0.000 abstract 1
239000000463 material Substances 0.000 abstract 1
239000003960 organic solvent Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Landscapes

Thiazole And Isothizaole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

JP62230074A 1987-09-14 1987-09-14 置換ジフェニルチアゾール誘導体からなる抗炎症剤 Expired - Lifetime JPH0753666B2 (ja)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
JP62230074A JPH0753666B2 (ja)	1987-09-14	1987-09-14	置換ジフェニルチアゾール誘導体からなる抗炎症剤

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP62230074A JPH0753666B2 (ja)	1987-09-14	1987-09-14	置換ジフェニルチアゾール誘導体からなる抗炎症剤

Publications (2)

Publication Number	Publication Date
JPS6475475A true JPS6475475A (en)	1989-03-22
JPH0753666B2 JPH0753666B2 (ja)	1995-06-07

Family

ID=16902136

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP62230074A Expired - Lifetime JPH0753666B2 (ja)	1987-09-14	1987-09-14	置換ジフェニルチアゾール誘導体からなる抗炎症剤

Country Status (1)

Country	Link
JP (1)	JPH0753666B2 (ja)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5145860A (en) *	1989-01-05	1992-09-08	Fujisawa Pharmaceutical Co., Ltd.	Thiazole compounds and pharmaceutical composition comprising the same
WO1992015570A1 (en) *	1991-03-07	1992-09-17	Hisamitsu Pharmaceutical Co., Inc.	Novel diphenylthyazole derivative
WO2001017995A1 (en) *	1999-09-10	2001-03-15	Merck & Co., Inc.	Tyrosine kinase inhibitors
US6872724B2 (en)	2002-07-24	2005-03-29	Merck & Co., Inc.	Polymorphs with tyrosine kinase activity
US6875767B2 (en)	2001-06-22	2005-04-05	Merck & Co., Inc.	(5-cyano-2-thiazolyl)amino-4-pyridine tyrosine kinase inhibitors
US7514566B2 (en)	2006-01-18	2009-04-07	Amgen, Inc.	Thiazole compounds and methods of use
US7897619B2 (en)	2007-07-17	2011-03-01	Amgen Inc.	Heterocyclic modulators of PKB
US7919504B2 (en)	2007-07-17	2011-04-05	Amgen Inc.	Thiadiazole modulators of PKB

Citations (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3458526A (en) *	1966-09-26	1969-07-29	Upjohn Co	Certain 2-amino-4,5-bis(p-methoxyphenyl)thiazoles
JPS50121269A (ja) *	1974-01-31	1975-09-23
JPS5455566A (en) *	1977-09-28	1979-05-02	Upjohn Co	Organic compound and pharmaceutical composition
JPS54160369A (en) *	1978-06-02	1979-12-19	Pfizer	Novel aminothiazoles
US4307106A (en) *	1978-06-02	1981-12-22	Pfizer Inc.	Aminothiazoles
JPS57118574A (en) *	1981-01-13	1982-07-23	Mitsui Toatsu Chem Inc	N-(4-phenylthiazol-2-yl)carbamate derivative, its preparation and medicinal composition containing the same
JPS58216186A (ja) *	1982-05-28	1983-12-15	バイエル・アクチエンゲゼルシヤフト	グアニジノチアゾ−ル誘導体、それらの製造法およびそれらの薬剤としての用途
JPS63243080A (ja) *	1987-03-12	1988-10-07	サノフイ	コリン作用系に作用する新規チアゾール誘導体、製造方法および医薬組成物

1987
- 1987-09-14 JP JP62230074A patent/JPH0753666B2/ja not_active Expired - Lifetime

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3458526A (en) *	1966-09-26	1969-07-29	Upjohn Co	Certain 2-amino-4,5-bis(p-methoxyphenyl)thiazoles
JPS50121269A (ja) *	1974-01-31	1975-09-23
JPS5455566A (en) *	1977-09-28	1979-05-02	Upjohn Co	Organic compound and pharmaceutical composition
JPS54160369A (en) *	1978-06-02	1979-12-19	Pfizer	Novel aminothiazoles
US4307106A (en) *	1978-06-02	1981-12-22	Pfizer Inc.	Aminothiazoles
JPS57118574A (en) *	1981-01-13	1982-07-23	Mitsui Toatsu Chem Inc	N-(4-phenylthiazol-2-yl)carbamate derivative, its preparation and medicinal composition containing the same
JPS58216186A (ja) *	1982-05-28	1983-12-15	バイエル・アクチエンゲゼルシヤフト	グアニジノチアゾ−ル誘導体、それらの製造法およびそれらの薬剤としての用途
JPS63243080A (ja) *	1987-03-12	1988-10-07	サノフイ	コリン作用系に作用する新規チアゾール誘導体、製造方法および医薬組成物

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5145860A (en) *	1989-01-05	1992-09-08	Fujisawa Pharmaceutical Co., Ltd.	Thiazole compounds and pharmaceutical composition comprising the same
WO1992015570A1 (en) *	1991-03-07	1992-09-17	Hisamitsu Pharmaceutical Co., Inc.	Novel diphenylthyazole derivative
WO2001017995A1 (en) *	1999-09-10	2001-03-15	Merck & Co., Inc.	Tyrosine kinase inhibitors
JP2003509342A (ja) *	1999-09-10	2003-03-11	メルクエンドカムパニーインコーポレーテッド	チロシンキナーゼ阻害薬
US6586423B2 (en)	1999-09-10	2003-07-01	Merck & Co., Inc.	Tyrosine kinase inhibitors
US6586424B2 (en)	1999-09-10	2003-07-01	Merck & Co., Inc.	Tyrosine kinase inhibitors
US6875767B2 (en)	2001-06-22	2005-04-05	Merck & Co., Inc.	(5-cyano-2-thiazolyl)amino-4-pyridine tyrosine kinase inhibitors
US6872724B2 (en)	2002-07-24	2005-03-29	Merck & Co., Inc.	Polymorphs with tyrosine kinase activity
US7514566B2 (en)	2006-01-18	2009-04-07	Amgen, Inc.	Thiazole compounds and methods of use
US8084479B2 (en)	2006-01-18	2011-12-27	Amgen Inc.	Thiazole compounds and methods of use
US7897619B2 (en)	2007-07-17	2011-03-01	Amgen Inc.	Heterocyclic modulators of PKB
US7919504B2 (en)	2007-07-17	2011-04-05	Amgen Inc.	Thiadiazole modulators of PKB

Also Published As

Publication number	Publication date
JPH0753666B2 (ja)	1995-06-07

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