JPS6479196A - Novel anthracycline derivative - Google Patents

Novel anthracycline derivative

Info

Publication number
JPS6479196A
JPS6479196A JP62236362A JP23636287A JPS6479196A JP S6479196 A JPS6479196 A JP S6479196A JP 62236362 A JP62236362 A JP 62236362A JP 23636287 A JP23636287 A JP 23636287A JP S6479196 A JPS6479196 A JP S6479196A
Authority
JP
Japan
Prior art keywords
formula
expressed
tetrahydropyranyladriamycin
coor
aralkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP62236362A
Other languages
Japanese (ja)
Inventor
Tomio Takeuchi
Shinichi Kondo
Daishiro Ikeda
Keiichi Ajito
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Microbial Chemistry Research Foundation
Original Assignee
Microbial Chemistry Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microbial Chemistry Research Foundation filed Critical Microbial Chemistry Research Foundation
Priority to JP62236362A priority Critical patent/JPS6479196A/en
Publication of JPS6479196A publication Critical patent/JPS6479196A/en
Pending legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:A compound expressed by formula I {R is OH, alkoxy, -COOR<1> [R<1> is H, (substituted)1-6C alkyl, aralkyl or aryl] or -CH(NHR<2>)COOR<3> [R<2> is H or monofunctional amino-protecting group; R<3> is H, (substituted)1-6C alkyl, aralkyl or aryl]; n is 0-3}. EXAMPLE:3'-N-(5-Methoxysalicylidene)-4'-O-tetrahydropyranyladriamycin. USE:An antitumor agent. PREPARATION:A free base of 4'-O-tetrahydropyranyladriamycin expressed by formula II is dissolved in an organic solvent and a salicylaldehyde derivative expressed by formula III is added to the resultant so and reacted therewith at ambient temperature or while being heated.
JP62236362A 1987-09-22 1987-09-22 Novel anthracycline derivative Pending JPS6479196A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP62236362A JPS6479196A (en) 1987-09-22 1987-09-22 Novel anthracycline derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP62236362A JPS6479196A (en) 1987-09-22 1987-09-22 Novel anthracycline derivative

Publications (1)

Publication Number Publication Date
JPS6479196A true JPS6479196A (en) 1989-03-24

Family

ID=16999673

Family Applications (1)

Application Number Title Priority Date Filing Date
JP62236362A Pending JPS6479196A (en) 1987-09-22 1987-09-22 Novel anthracycline derivative

Country Status (1)

Country Link
JP (1) JPS6479196A (en)

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