JPS649932A - Soft capsule preparation using newly combined component as the base - Google Patents
Soft capsule preparation using newly combined component as the baseInfo
- Publication number
- JPS649932A JPS649932A JP62164145A JP16414587A JPS649932A JP S649932 A JPS649932 A JP S649932A JP 62164145 A JP62164145 A JP 62164145A JP 16414587 A JP16414587 A JP 16414587A JP S649932 A JPS649932 A JP S649932A
- Authority
- JP
- Japan
- Prior art keywords
- base material
- cap
- soft capsule
- base
- capsules
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000007901 soft capsule Substances 0.000 title abstract 4
- 238000002360 preparation method Methods 0.000 title abstract 2
- 229920008347 Cellulose acetate propionate Polymers 0.000 abstract 4
- 239000002202 Polyethylene glycol Substances 0.000 abstract 4
- 239000000463 material Substances 0.000 abstract 4
- 229920001223 polyethylene glycol Polymers 0.000 abstract 4
- HKQOBOMRSSHSTC-UHFFFAOYSA-N cellulose acetate Chemical compound OC1C(O)C(O)C(CO)OC1OC1C(CO)OC(O)C(O)C1O.CC(=O)OCC1OC(OC(C)=O)C(OC(C)=O)C(OC(C)=O)C1OC1C(OC(C)=O)C(OC(C)=O)C(OC(C)=O)C(COC(C)=O)O1.CCC(=O)OCC1OC(OC(=O)CC)C(OC(=O)CC)C(OC(=O)CC)C1OC1C(OC(=O)CC)C(OC(=O)CC)C(OC(=O)CC)C(COC(=O)CC)O1 HKQOBOMRSSHSTC-UHFFFAOYSA-N 0.000 abstract 3
- 229920003132 hydroxypropyl methylcellulose phthalate Polymers 0.000 abstract 3
- 229940031704 hydroxypropyl methylcellulose phthalate Drugs 0.000 abstract 3
- YYGNTYWPHWGJRM-UHFFFAOYSA-N (6E,10E,14E,18E)-2,6,10,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaene Chemical compound CC(C)=CCCC(C)=CCCC(C)=CCCC=C(C)CCC=C(C)CCC=C(C)C YYGNTYWPHWGJRM-UHFFFAOYSA-N 0.000 abstract 1
- BHEOSNUKNHRBNM-UHFFFAOYSA-N Tetramethylsqualene Natural products CC(=C)C(C)CCC(=C)C(C)CCC(C)=CCCC=C(C)CCC(C)C(=C)CCC(C)C(C)=C BHEOSNUKNHRBNM-UHFFFAOYSA-N 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 239000011248 coating agent Substances 0.000 abstract 1
- 238000000576 coating method Methods 0.000 abstract 1
- PRAKJMSDJKAYCZ-UHFFFAOYSA-N dodecahydrosqualene Natural products CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C PRAKJMSDJKAYCZ-UHFFFAOYSA-N 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 229940031439 squalene Drugs 0.000 abstract 1
- TUHBEKDERLKLEC-UHFFFAOYSA-N squalene Natural products CC(=CCCC(=CCCC(=CCCC=C(/C)CCC=C(/C)CC=C(C)C)C)C)C TUHBEKDERLKLEC-UHFFFAOYSA-N 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Landscapes
- Medicinal Preparation (AREA)
Abstract
PURPOSE:To provide enteric soft capsules of high efficiency easily by using a base material consisting of polyethylene glycol (PG), cellulose acetate propionate (CAP) or hydroxypropyl methyl cellulose phthalate (HP). CONSTITUTION:The base material is prepared by admixing CAP or HP to PG and its equivalent substance such as squalene at a PG/CAP weight ratio of (70-97):(30-3). The base material is combined with a soft capsule drug to give the subject preparation. The base material according to the present invention is a clear liquid which is a little viscous at room temperature, and becomes a white and opaque solid, and insoluble, when meets water. The soft capsules can be obtained through a simple process in no need of coating such as in case of tablets, even when enteric or gradually releasing capsules are produced.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP62164145A JPS649932A (en) | 1987-07-01 | 1987-07-01 | Soft capsule preparation using newly combined component as the base |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP62164145A JPS649932A (en) | 1987-07-01 | 1987-07-01 | Soft capsule preparation using newly combined component as the base |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS649932A true JPS649932A (en) | 1989-01-13 |
Family
ID=15787603
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP62164145A Pending JPS649932A (en) | 1987-07-01 | 1987-07-01 | Soft capsule preparation using newly combined component as the base |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS649932A (en) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994000128A1 (en) * | 1992-06-22 | 1994-01-06 | Lunar Corporation | ORAL 1α-HYDROXYPREVITAMIN D |
| WO1994014421A3 (en) * | 1992-12-23 | 1994-08-18 | Diolaiti Luigi | Process for preparing controlled release pharmaceutical forms and the forms thus obtained |
| WO1995011024A1 (en) * | 1993-10-19 | 1995-04-27 | The Procter & Gamble Company | Picosulphate dosage form |
| JPWO2003072085A1 (en) * | 2002-02-27 | 2005-06-16 | 塩野義製薬株式会社 | Solid formulation with improved absorption of poorly water-soluble drugs |
| JP2005531531A (en) * | 2002-04-15 | 2005-10-20 | パリス,ローレンス | Liquid compositions for sustained-release soft capsules and methods for producing them |
| EP1940365A2 (en) * | 2005-10-24 | 2008-07-09 | Eastman Chemical Company | Liquid dosage forms having enteric properties of delayed and then sustained release |
| JP2011057712A (en) * | 1998-11-04 | 2011-03-24 | Mayne Pharma Plc | Oral administration of adenosine analogue |
-
1987
- 1987-07-01 JP JP62164145A patent/JPS649932A/en active Pending
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994000128A1 (en) * | 1992-06-22 | 1994-01-06 | Lunar Corporation | ORAL 1α-HYDROXYPREVITAMIN D |
| WO1994014421A3 (en) * | 1992-12-23 | 1994-08-18 | Diolaiti Luigi | Process for preparing controlled release pharmaceutical forms and the forms thus obtained |
| US5662935A (en) * | 1992-12-23 | 1997-09-02 | Saitec S.R.L. | Process for preparing controlled release pharmaceutical forms and the forms thus obtained |
| WO1995011024A1 (en) * | 1993-10-19 | 1995-04-27 | The Procter & Gamble Company | Picosulphate dosage form |
| US5631022A (en) * | 1993-10-19 | 1997-05-20 | The Procter & Gamble Company | Picosulfate dosage form |
| JP2011057712A (en) * | 1998-11-04 | 2011-03-24 | Mayne Pharma Plc | Oral administration of adenosine analogue |
| JPWO2003072085A1 (en) * | 2002-02-27 | 2005-06-16 | 塩野義製薬株式会社 | Solid formulation with improved absorption of poorly water-soluble drugs |
| JP2005531531A (en) * | 2002-04-15 | 2005-10-20 | パリス,ローレンス | Liquid compositions for sustained-release soft capsules and methods for producing them |
| JP4918212B2 (en) * | 2002-04-15 | 2012-04-18 | パリス,ローレンス | Liquid compositions for sustained-release soft capsules and methods for producing them |
| EP1940365A2 (en) * | 2005-10-24 | 2008-07-09 | Eastman Chemical Company | Liquid dosage forms having enteric properties of delayed and then sustained release |
| JP2009512699A (en) * | 2005-10-24 | 2009-03-26 | イーストマン ケミカル カンパニー | Liquid dosage form with enteric properties of delayed release followed by sustained release |
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