KR920700252A - 콘택트렌즈에 관한 색상 결합 메카니즘 - Google Patents
콘택트렌즈에 관한 색상 결합 메카니즘Info
- Publication number
- KR920700252A KR920700252A KR1019900702589A KR900702589A KR920700252A KR 920700252 A KR920700252 A KR 920700252A KR 1019900702589 A KR1019900702589 A KR 1019900702589A KR 900702589 A KR900702589 A KR 900702589A KR 920700252 A KR920700252 A KR 920700252A
- Authority
- KR
- South Korea
- Prior art keywords
- lens
- alkyl
- polymer
- hydrogen
- functional group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J7/00—Chemical treatment or coating of shaped articles made of macromolecular substances
- C08J7/04—Coating
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29D—PRODUCING PARTICULAR ARTICLES FROM PLASTICS OR FROM SUBSTANCES IN A PLASTIC STATE
- B29D11/00—Producing optical elements, e.g. lenses or prisms
- B29D11/00009—Production of simple or compound lenses
- B29D11/00038—Production of contact lenses
- B29D11/00048—Production of contact lenses composed of parts with dissimilar composition
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- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B1/00—Optical elements characterised by the material of which they are made; Optical coatings for optical elements
- G02B1/04—Optical elements characterised by the material of which they are made; Optical coatings for optical elements made of organic materials, e.g. plastics
- G02B1/041—Lenses
- G02B1/043—Contact lenses
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- G—PHYSICS
- G02—OPTICS
- G02C—SPECTACLES; SUNGLASSES OR GOGGLES INSOFAR AS THEY HAVE THE SAME FEATURES AS SPECTACLES; CONTACT LENSES
- G02C7/00—Optical parts
- G02C7/02—Lenses; Lens systems ; Methods of designing lenses
- G02C7/04—Contact lenses for the eyes
- G02C7/049—Contact lenses having special fitting or structural features achieved by special materials or material structures
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2300/00—Characterised by the use of unspecified polymers
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2339/00—Characterised by the use of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen; Derivatives of such polymers
- C08J2339/04—Homopolymers or copolymers of monomers containing heterocyclic rings having nitrogen as ring member
- C08J2339/06—Homopolymers or copolymers of N-vinyl-pyrrolidones
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2433/00—Characterised by the use of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides, or nitriles thereof; Derivatives of such polymers
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/31504—Composite [nonstructural laminate]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/31504—Composite [nonstructural laminate]
- Y10T428/31855—Of addition polymer from unsaturated monomers
Landscapes
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Ophthalmology & Optometry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Mechanical Engineering (AREA)
- Manufacturing & Machinery (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Eyeglasses (AREA)
- Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Joining Of Glass To Other Materials (AREA)
- Surface Treatment Of Optical Elements (AREA)
- Coloring (AREA)
- Coating Of Shaped Articles Made Of Macromolecular Substances (AREA)
- Treatments Of Macromolecular Shaped Articles (AREA)
Abstract
Description
Claims (15)
- a) 하나 이상의 -COOH, -OH 및 -NH-R(여기서, R은 수소 또는 C1내지 C8알킬이다)중에서 선택된 작용성 그룹을 갖는 비친수성 중합체 또는 친수성 중합체로 조성된 콘택트 렌즈를 수득하고; b) 렌즈 표면의 한 분획 이상에 하나 이상의 안료, 하나 이상의 -COOH, -OH 및 -NH-R(여기서, R은 수소 또는 C1내지 C8알킬이다)중에서 선택된 작용성 그룹을 갖는 결합 중합체, 및 방향족 환의 일부인 탄소 원자에 결합되거나 질소 또는 산소원자에 결합된 일반식 -CH2-O-R1(여기서, R1은 수소 또는 C1내지 C16알킬이다)의 분자당 둘 이상의 작용성 그룹을 갖는 정착제를 함유하는 색도료(color coat)를 피복시키며, c) 피복된 렌즈를 색도료가 렌즈에 접착하는 조건에 적용시키는 단계를 특징으로 하여, 착색된 콘택즈 렌즈를 제조하는 방법.
- 제1항에 있어서, 렌즈 중합체가 친수성이고 하나 이상의 -COOH, -OH 및 -NH-R(여기서, R은 수소 또는 C1내지 C8알킬이다)중에서 선택된 작용성 그룹을 갖는 방법.
- 제1항 또는 2항에 있어서, 렌즈 중합체 및 결합 중합체가 하드록시에틸 메트아크릴레이트, 에톡시에틸 메트아크릴레이트 및 메트아크릴산을 포함하는 단량체의 혼합물로부터 형성되는 방법.
- 제1항에 있어서, 렌즈 중합체가 친수성이고 비닐 피톨리돈을 포함하는 단량체 및 소수성 단량체로부터 형성되는 방법.
- 제1항 내지 4항 중 어느 한 항에 있어서, 정착제가 간단한 하기 일반식의 화합물, 또는 이의 중합체 및 이의 배합물인 방법.상기식에서, R2는 CH3또는 C2H5이고, R는 탄소-CH-탄소 단일 결합이거나, C1내지 C6알킬렌이며, R5는 독립적으로 C1내지 C6알킬이고, R4는 각각 독립적으로 H, -CH3, -C2H3, -C3H7또는 -C4H9이며, R6는 각각 독립적으로 H, -CH3또는 이소부틸이다.
- 제1항 내지 5항 중 어느 한 항에 따른 방법으로 제조한 렌즈.
- a) 하나 이상의 -COOH, -OH 및 -NH-R(여기서, R은 수소 또는 C1내지 C8알킬이다)중에서 선택된 작용성 그룹을 갖는 비친수성 중합체 또는 친수성 중합체로 조성된 콘택트 렌즈를 수득하고; b) 렌즈 표면의 한 분획 이상에 하나 이상의 안료, 및 방향족 환의 일부인 탄소 원자에 결합되거나 질소 또는 산소원자에 결합된 일반식 -CH2-O-R1(여기서, R1은 수소 또는 C1내지 C16알킬이다)의 작용성 그룹을 갖는 정착제를 함유하는 색도료를 피복시키며, c) 피복된 렌즈를 색도료가 렌즈에 접착하는 조건에 적용시키는 단계를 특징으로 하여, 착색된 콘택즈 렌즈를 제조하는 방법.
- 제7항에 따른 방법으로 제조한 렌즈.
- a) 방향족 환의 일부인 탄소원자에 결합되거나 질소 또는 산소원자에 결합된 일반식 -CH2-O-R1(여기서, R1은 수소 또는 C1내지 C16알킬이다)의 작용성 그룹을 갖는 중합체로 조성된 콘택트 렌즈를 수득하고; b) 렌즈 표면의 한 분획 이상에 하나 이상의 안료, 하나 이상의 -COOH, -OH 및 -NH-R(여기서, R은 수소 또는 C1내지 C8알킬이다)중에서 선택된 작용성 그룹을 갖는 결합 중합체를 함유하는 색도료를 피복시키며, c) 피복된 렌즈를 색도료가 렌즈에 접착하는 조건에 적용시키는 단계를 특징으로 하여, 착색된 콘택즈 렌즈를 제조하는 방법.
- 제9항에 따른 방법으로 제조한 렌즈.
- a) 방향족 환의 일부인 탄소원자에 결합되거나 질소 또는 산소원자에 결합된 일반식 -CH2-O-R1(여기서, R1은 수소 또는 C1내지 C16알킬이다)의 분자당 둘 이상의 작용성 그룹을 갖는 중합체로 조성된 콘택트 렌즈를 수득하고; b) 렌즈 표면의 한 분획 이상에 하나 이상의 안료, 및 방향족 환의 일부인 탄소 원자에 결합되거나 질소 또는 산소원자에 결합된 일반식 -CH2-O-R1(여기서, R1은 수소 또는 C1내지 C16알킬이다)의 작용성 그룹을 갖는결합 중합체, 및 하나 이상의 -COOH, -OH 및 -NH-R(여기서, R은 수소 또는 C1내지 C8알킬이다)중에서 선택된 분자당 둘 이상의 작용을 갖는 정착제를 함유하는 색도료를 피복시키며, c) 피복된 렌즈를 색도료가 렌즈에 접착하는 조건에 적용시키는 단계를 특징으로 하여, 착색된 콘택즈 렌즈를 제조하는 방법.
- 제11항에 따른 방법으로 제조한 렌즈.
- a) 중합체로 조성된 렌즈; 및 b) 렌즈 표면의 한 분획 이상에서 정착제와 혼합된 안료〔여기서, 정착제와 렌즈 중합체는 하나 이상의 -COOH, -OH 및 -NH-R(여기서, R은 수소 또는 C1내지 C8알킬이다)중에서 선택된 제1작용성 그룹을 방향족 환의 일부인 탄소원자에 결합되거나 질소 또는 산소원자에 결합된 일반식 -CH2-O-R1의 제2작용성 그룹(여기서, R1은 수소 또는 C1내지 C16알킬이다)과 반응시킴으로써 서로 결합된 것이다〕를 포함하는 착색된 콘택트 렌즈.
- 제13항에 있어서, 렌즈 중합체가 아크릴산, 메트아크릴산, 아크릴산 또는 메트아크릴산의 하이드록시 C1내지 C8알킬 에스테르, 아크릴산 또는 메트아크릴산의 아미노 C1내지 C8알킬 에스테르, 아크릴산 또는 메티아크릴산의 글리세롤 에스테르 및 이의 혼합물 중에서 선택된 하나 이상의 단량체로부터 형성된 착색된 콘택트 렌즈.
- 제13항에 있어서, 렌즈 중합체가 아크릴산, 메트아크릴산 및 하이드록시에틸 메트아크릴레이트 중에서 선택된 하나 이상의 단량체로부터 형성된 렌즈.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33807789A | 1989-04-14 | 1989-04-14 | |
| US338077 | 1989-04-14 | ||
| US338,077 | 1989-04-14 | ||
| PCT/US1990/001868 WO1990012840A2 (en) | 1989-04-14 | 1990-04-12 | Color binding mechanism for contact lenses |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR920700252A true KR920700252A (ko) | 1992-02-19 |
| KR0171571B1 KR0171571B1 (ko) | 1999-05-01 |
Family
ID=23323315
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019900702589A Expired - Fee Related KR0171571B1 (ko) | 1989-04-14 | 1990-04-12 | 콘택트렌즈에 관한 색상 결합 메카니즘 |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US5272010A (ko) |
| EP (2) | EP0393532B1 (ko) |
| JP (1) | JPH0623264B2 (ko) |
| KR (1) | KR0171571B1 (ko) |
| CN (1) | CN1045126C (ko) |
| AT (1) | ATE139549T1 (ko) |
| AU (1) | AU631425B2 (ko) |
| BR (1) | BR9007294A (ko) |
| CA (1) | CA2051387C (ko) |
| CZ (1) | CZ187690A3 (ko) |
| DE (1) | DE69027475T2 (ko) |
| DK (1) | DK0393532T3 (ko) |
| ES (1) | ES2088395T3 (ko) |
| IL (1) | IL94072A (ko) |
| NZ (1) | NZ233317A (ko) |
| PL (1) | PL163759B1 (ko) |
| PT (1) | PT93750B (ko) |
| RU (1) | RU2049097C1 (ko) |
| SG (1) | SG43306A1 (ko) |
| WO (1) | WO1990012840A2 (ko) |
| ZA (1) | ZA902842B (ko) |
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| US5266077A (en) * | 1992-11-09 | 1993-11-30 | Ciba-Geigy Corporation | Method for tinting a hydrophilic contact lens |
| US5770259A (en) * | 1994-11-10 | 1998-06-23 | 2C Optics, Inc. | Quantitative tinting |
| US8039026B1 (en) | 1997-07-28 | 2011-10-18 | Johnson & Johnson Consumer Companies, Inc | Methods for treating skin pigmentation |
| US6500481B1 (en) | 1998-06-11 | 2002-12-31 | Johnson & Johnson Vision Care, Inc. | Biomedical devices with amid-containing coatings |
| US8106094B2 (en) | 1998-07-06 | 2012-01-31 | Johnson & Johnson Consumer Companies, Inc. | Compositions and methods for treating skin conditions |
| US8093293B2 (en) | 1998-07-06 | 2012-01-10 | Johnson & Johnson Consumer Companies, Inc. | Methods for treating skin conditions |
| US6750229B2 (en) | 1998-07-06 | 2004-06-15 | Johnson & Johnson Consumer Companies, Inc. | Methods for treating skin pigmentation |
| US6183083B1 (en) * | 1998-09-08 | 2001-02-06 | Wesley-Jessen Corporation | Contact lens comprising a violet tint |
| US6149842A (en) * | 1998-11-12 | 2000-11-21 | Novartis Ag | Methods and compositions for manufacturing tinted ophthalmic lenses |
| US7985404B1 (en) | 1999-07-27 | 2011-07-26 | Johnson & Johnson Consumer Companies, Inc. | Reducing hair growth, hair follicle and hair shaft size and hair pigmentation |
| US6478423B1 (en) | 1999-10-12 | 2002-11-12 | Johnson & Johnson Vison Care, Inc. | Contact lens coating selection and manufacturing process |
| US6488375B2 (en) | 1999-10-28 | 2002-12-03 | Ocular Sciences, Inc. | Tinted contact lens and method for making same |
| US7267846B2 (en) | 1999-11-01 | 2007-09-11 | Praful Doshi | Tinted lenses and methods of manufacture |
| US6880932B2 (en) | 1999-11-01 | 2005-04-19 | Praful Doshi | Tinted lenses and methods of manufacture |
| US7048375B2 (en) | 1999-11-01 | 2006-05-23 | Praful Doshi | Tinted lenses and methods of manufacture |
| CA2388655C (en) | 1999-11-01 | 2010-12-14 | Praful Doshi | Tinted lenses and methods of manufacture |
| US7309688B2 (en) | 2000-10-27 | 2007-12-18 | Johnson & Johnson Consumer Companies | Topical anti-cancer compositions and methods of use thereof |
| US6451236B1 (en) | 2000-02-02 | 2002-09-17 | Gentex Optics, Inc. | Method of making photochromic thermoplastics |
| US6811259B2 (en) * | 2000-06-12 | 2004-11-02 | Novartis Ag | Printing colored contact lenses |
| SG121688A1 (en) * | 2000-08-24 | 2006-05-26 | Oculus Contact Lens Mfg Pte Lt | Ink for printing contact lenses, a printing process for coloured contact lenses, and lenses made thereby |
| US8431550B2 (en) | 2000-10-27 | 2013-04-30 | Johnson & Johnson Consumer Companies, Inc. | Topical anti-cancer compositions and methods of use thereof |
| KR20020063382A (ko) * | 2001-01-29 | 2002-08-03 | 주식회사 티씨 싸이언스 | 미용 칼라 콘택트렌즈 및 그의 제조방법 |
| US20020133889A1 (en) * | 2001-02-23 | 2002-09-26 | Molock Frank F. | Colorants for use in tinted contact lenses and methods for their production |
| CA2371965C (en) * | 2001-02-23 | 2010-07-06 | Johnson & Johnson Vision Care, Inc. | Colorants for use in tinted contact lenses and methods for their production |
| US7192615B2 (en) | 2001-02-28 | 2007-03-20 | J&J Consumer Companies, Inc. | Compositions containing legume products |
| CA2440900A1 (en) * | 2001-03-16 | 2002-09-26 | Novartis Ag | Colored printing ink for contact lenses |
| US6767097B2 (en) | 2001-03-29 | 2004-07-27 | Daniel G. Streibig | Colored contact lens and method of making same |
| US6655804B2 (en) * | 2001-06-29 | 2003-12-02 | Daniel G. Streibig | Colored contact lens and method of making same |
| US6733126B2 (en) | 2001-06-29 | 2004-05-11 | Daniel G. Streibig | Colored contact lens and method of making same |
| US20030165015A1 (en) * | 2001-12-05 | 2003-09-04 | Ocular Sciences, Inc. | Coated contact lenses and methods for making same |
| RU2258948C1 (ru) * | 2003-02-26 | 2005-08-20 | Международный центр "Институт прикладной оптики" Национальной академии наук Украины | Термочувствительная контактная линза |
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| CN102667575B (zh) * | 2009-12-17 | 2014-03-19 | 诺华股份有限公司 | 用于制造有色接触透镜的衬垫转印方法 |
| US10413506B2 (en) | 2010-04-03 | 2019-09-17 | Praful Doshi | Medical devices including medicaments and methods of making and using same including enhancing comfort, enhancing drug penetration, and treatment of myopia |
| WO2011123180A1 (en) | 2010-04-03 | 2011-10-06 | Praful Doshi | Medical devices including medicaments and methods of making and using same |
| ES2980213T3 (es) | 2010-07-30 | 2024-09-30 | Alcon Inc | Lentes de hidrogel de silicona con superficies ricas en agua |
| KR20120039398A (ko) * | 2010-10-15 | 2012-04-25 | 삼성전자주식회사 | 에어로젤, 에어로젤용 조성물, 에어로젤 복합체 및 이들의 제조방법 |
| CA2851668C (en) | 2011-10-12 | 2016-08-16 | Novartis Ag | Method for making uv-absorbing ophthalmic lenses by coating |
| CN104023959B (zh) | 2011-12-31 | 2016-08-03 | 诺华股份有限公司 | 具有识别标记的接触透镜 |
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-
1990
- 1990-04-12 PT PT93750A patent/PT93750B/pt not_active IP Right Cessation
- 1990-04-12 EP EP90107106A patent/EP0393532B1/en not_active Expired - Lifetime
- 1990-04-12 SG SG1996007875A patent/SG43306A1/en unknown
- 1990-04-12 RU SU905010138A patent/RU2049097C1/ru active
- 1990-04-12 ES ES90107106T patent/ES2088395T3/es not_active Expired - Lifetime
- 1990-04-12 US US07/768,910 patent/US5272010A/en not_active Expired - Lifetime
- 1990-04-12 IL IL9407290A patent/IL94072A/en not_active IP Right Cessation
- 1990-04-12 KR KR1019900702589A patent/KR0171571B1/ko not_active Expired - Fee Related
- 1990-04-12 AU AU55290/90A patent/AU631425B2/en not_active Ceased
- 1990-04-12 CA CA002051387A patent/CA2051387C/en not_active Expired - Fee Related
- 1990-04-12 DK DK90107106.8T patent/DK0393532T3/da active
- 1990-04-12 ZA ZA902842A patent/ZA902842B/xx unknown
- 1990-04-12 JP JP2506440A patent/JPH0623264B2/ja not_active Expired - Fee Related
- 1990-04-12 EP EP90906695A patent/EP0467977A1/en active Pending
- 1990-04-12 WO PCT/US1990/001868 patent/WO1990012840A2/en not_active Ceased
- 1990-04-12 NZ NZ233317A patent/NZ233317A/en unknown
- 1990-04-12 AT AT90107106T patent/ATE139549T1/de not_active IP Right Cessation
- 1990-04-12 DE DE69027475T patent/DE69027475T2/de not_active Expired - Fee Related
- 1990-04-12 BR BR909007294A patent/BR9007294A/pt not_active IP Right Cessation
- 1990-04-13 CN CN90102059A patent/CN1045126C/zh not_active Expired - Fee Related
- 1990-04-13 PL PL90284779A patent/PL163759B1/pl unknown
- 1990-04-13 CZ CS901876A patent/CZ187690A3/cs unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL94072A0 (en) | 1991-01-31 |
| CN1045126C (zh) | 1999-09-15 |
| SG43306A1 (en) | 1997-10-17 |
| JPH0623264B2 (ja) | 1994-03-30 |
| DK0393532T3 (da) | 1996-08-19 |
| EP0393532B1 (en) | 1996-06-19 |
| DE69027475T2 (de) | 1996-12-12 |
| HK1007434A1 (en) | 1999-04-09 |
| WO1990012840A2 (en) | 1990-11-01 |
| CA2051387C (en) | 1996-06-25 |
| EP0467977A1 (en) | 1992-01-29 |
| RU2049097C1 (ru) | 1995-11-27 |
| CZ187690A3 (en) | 1995-02-15 |
| ATE139549T1 (de) | 1996-07-15 |
| PT93750B (pt) | 1996-10-31 |
| PT93750A (pt) | 1990-11-20 |
| BR9007294A (pt) | 1992-03-03 |
| WO1990012840A3 (en) | 1990-11-29 |
| KR0171571B1 (ko) | 1999-05-01 |
| JPH04500696A (ja) | 1992-02-06 |
| DE69027475D1 (de) | 1996-07-25 |
| EP0393532A3 (en) | 1990-11-28 |
| PL163759B1 (pl) | 1994-04-29 |
| AU5529090A (en) | 1990-11-16 |
| ZA902842B (en) | 1990-12-28 |
| CN1046575A (zh) | 1990-10-31 |
| CA2051387A1 (en) | 1990-10-15 |
| ES2088395T3 (es) | 1996-08-16 |
| US5272010A (en) | 1993-12-21 |
| AU631425B2 (en) | 1992-11-26 |
| NZ233317A (en) | 1992-04-28 |
| EP0393532A2 (en) | 1990-10-24 |
| IL94072A (en) | 1994-06-24 |
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