KR920703473A - 페리틴 유사체 - Google Patents

페리틴 유사체

Info

Publication number
KR920703473A
KR920703473A KR1019920700351A KR920700351A KR920703473A KR 920703473 A KR920703473 A KR 920703473A KR 1019920700351 A KR1019920700351 A KR 1019920700351A KR 920700351 A KR920700351 A KR 920700351A KR 920703473 A KR920703473 A KR 920703473A
Authority
KR
South Korea
Prior art keywords
ferritin
analog
globules
apo
ammonium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
KR1019920700351A
Other languages
English (en)
Other versions
KR950002917B1 (ko
Inventor
프란시스 몬지크 브루스
Original Assignee
제임스 클리프튼 보올딩
몬산토 캄파니
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 제임스 클리프튼 보올딩, 몬산토 캄파니 filed Critical 제임스 클리프튼 보올딩
Publication of KR920703473A publication Critical patent/KR920703473A/ko
Application granted granted Critical
Publication of KR950002917B1 publication Critical patent/KR950002917B1/ko
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B35/00—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/5115—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5169—Proteins, e.g. albumin, gelatin
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/06—Making microcapsules or microballoons by phase separation
    • B01J13/08—Simple coacervation, i.e. addition of highly hydrophilic material
    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B35/00—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
    • C04B35/01—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on oxide ceramics
    • C04B35/10—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on oxide ceramics based on aluminium oxide
    • C04B35/111—Fine ceramics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/79—Transferrins, e.g. lactoferrins, ovotransferrins
    • G—PHYSICS
    • G03—PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03C—PHOTOSENSITIVE MATERIALS FOR PHOTOGRAPHIC PURPOSES; PHOTOGRAPHIC PROCESSES, e.g. CINE, X-RAY, COLOUR, STEREO-PHOTOGRAPHIC PROCESSES; AUXILIARY PROCESSES IN PHOTOGRAPHY
    • G03C1/00—Photosensitive materials
    • G03C1/005—Silver halide emulsions; Preparation thereof; Physical treatment thereof; Incorporation of additives therein
    • G03C1/015—Apparatus or processes for the preparation of emulsions

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Ceramic Engineering (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Materials Engineering (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nanotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Biomedical Technology (AREA)
  • Structural Engineering (AREA)
  • Manufacturing & Machinery (AREA)
  • Biochemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Bipolar Transistors (AREA)
  • Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Compositions Of Oxide Ceramics (AREA)

Abstract

내용 없음

Description

페리틴 유사체
[도면의 간단한 설명]
제1도는 10킬로볼트 전자비임을 사용하여 알루미늄 페리틴은 유사체로 제조된 융합되고, 고도로 균일한 세라믹 물품의 표면을 20,000배로 확대한 투과 전자현미경사진(TEM)이다.
제2도와 제3도는 페리틴 유사체로부터 유도된 융합 알루미나 소구체의 얇고 평편한 외피를 갖는 세라믹 물품을 보여주는 투과 전자현미경사진(TEM)이다.
제4도는 약 100옹그스트롬의 실질적으로 단일형식의 크기분포를 갖는 균일한 알루미나 입자를 나타내는 TEM이다.
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (20)

  1. 페리틴 유사체.
  2. 제1항에 있어서. 페리하이드라이트가 본래 없는 무기 코아를 가짐을 특징으로 하는 페리틴 유사체.
  3. 제2항에 있어서, 금속이 알루미늄, 암모늄, 바륨, 크로뮴, 코발트, 구리, 유로퓸, 가돌리늄, 철, 란타늄, 리튬, 마그네슘, 망간, 네오디뮴, 포타슘, 소듐, 은, 티타늄, 우라늄, 이테르븀, 이트륨이나, 또는 지로코늄이나 이의 혼합물인 금속염, 금속 수산화물이나 금속 산화물을 포함함을 특징으로 하는 페리틴 유사체.
  4. 제3항에 있어서, 아세테이트, 암모늄, 보롬화물, 탄산염, 염화물, 불화물, 개미산염, 요오드화물, 질산염, 아질산염, 옥살산염, 인산염, 아인산염, 황산염, 황화물이나 또는 아황산염 이온류나 또는 이의 혼합물의 염을 포함함을 특징으로 하는 페리틴 유사체.
  5. 제1항에 있어서, 알루미늄 페리틴 유사체임을 특징으로 하는 페리틴 유사체.
  6. 제1항에 있어서, 은 페리틴 유사체임을 특징으로 하는 페리틴 유사체.
  7. 제1항에 있어서, 칼슘 플루오라이드 페리틴 유사체임을 특징으로 하는 페리틴 유사체.
  8. 제1항에 있어서, 본질적으로 유기코아를 가짐을 특징으로 하는 페리틴 유사체.
  9. 페리하이드라이트가 본질적으로 없는 아포레리틴 안에서 성장하는 소구체.
  10. 제9항에 있어서, 본질적으로 100옹그스트롬 이하의 단일형식의 공칭직경을 가짐을 특징으로 하는 소구체.
  11. 제10항에 있어서, 금속이 알루미늄, 암모늄, 바륨, 크로뮴, 코발트, 구리, 유로퓸, 가돌리늄, 철, 란타늄, 리튬, 마그네슘, 망간, 네오디뮴, 포타슘, 은, 소듐, 티타늄, 우라늄, 이테르븀, 이트륨이나 지로코늄이나 또는 이의 혼합물인 금속염, 금속 수산화물이나 금속 산화물을 포함하고, 여기서 상기 염은 아세테이트, 암모늄, 보롬화물, 탄산염, 염화물, 불화물, 개미산염, 요오드화물, 질산염, 아질산염, 옥살산염, 인산염, 아인산염, 황산염, 황화물이나 또는 아황산염 이온류나 이의 혼합물로 구성된 군에서 선택된 음이온류를 포함함을 특징으로 하는 소구체.
  12. 제10항에 있어서, 본질적으로 유기조성물로 구성됨을 특징으로 하는 소구체.
  13. 제10항에 있어서, 카본으로 피복된 무기 소구체로 구성됨을 특징으로 하는 소구체.
  14. 아포 페리틴을 투과하기 위한 비-페리하이드라이트 형성용제를 공급함을 포함하는 페리틴 유사체의 제조방법.
  15. 제14항에 있어서, 상기 용제는 알루미늄, 암모늄, 바륨, 크로뮴, 코발트, 구리, 유로퓸, 가도리늄, 철, 란타늄, 리튬, 마그네슘, 망간, 네오디뮴, 포타슘, 은, 소듐, 티타늄, 우라늄, 이테르븀, 이트륨이나, 또는 지로코늄이나 이의 혼합물의 양이온류와 아세테이트, 브롬화물, 탄산염, 염화물, 불화물, 개미산염, 요오드화물, 질산염, 아질산염, 옥살산염, 인산염, 아인산염, 황산염, 황화물이나 또는 이의 혼합물의 음이온류를 포함함을 특징으로 하는 방법.
  16. 제14항에 있어서, 상기용제는 유기화합물을 포함함을 특징으로 하는 방법.
  17. 다음의 (a)(b)(c)(d)를 포함하는 무기입자의 제조방법.
    (a) 아포 페리틴과 비-페리하이드라이트-생성용재를 포함하는 매질을 결합하고, (b) 폐리하이드라이트가 본질적으로 없는 코아를 가지는 페리틴 유사체를 형성하기 위한 상기 아포 페리틴을 투과하기에 충분한 용제를 공급하고, (c) 아포 페리틴 소단위체와 코아를 제공하기 위해 분해 환경에 페리틴 유사체를 노출시키고, (d) 소구체로서 상기 코아를 피복한다.
  18. 제17항에 있어서, 상기 해체 환경은 1과 4사이 또는 9와 13사이의 pH를 갖는 수성 매질임을 특징으로 하는 방법.
  19. 제18항에 있어서, 더우기 상기 아포 페리틴 소단위체를 아포 페리틴으로 분리 및 생성함을 특징으로 하는 방법.
  20. 본질적으로 페리하이드라이트가 없고 100옹그스트롬 이하의 최대 직경을 갖는 무기 소구체를 포함하는 모놀리식 물품.
    ※ 참고사항 : 최초출원 내용에 의하여 공개되는 것임.
KR1019920700351A 1989-08-18 1990-08-03 페리틴 유사체 Expired - Fee Related KR950002917B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US39593489A 1989-08-18 1989-08-18
US07/395,934 1989-08-18
PCT/US1990/004348 WO1991002704A1 (en) 1989-08-18 1990-08-03 Ferritin analogs

Publications (2)

Publication Number Publication Date
KR920703473A true KR920703473A (ko) 1992-12-18
KR950002917B1 KR950002917B1 (ko) 1995-03-28

Family

ID=23565152

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019920700351A Expired - Fee Related KR950002917B1 (ko) 1989-08-18 1990-08-03 페리틴 유사체

Country Status (11)

Country Link
US (2) US5304382A (ko)
EP (1) EP0487615B1 (ko)
JP (1) JPH04507255A (ko)
KR (1) KR950002917B1 (ko)
AT (1) ATE99656T1 (ko)
AU (1) AU641936B2 (ko)
CA (1) CA2064069A1 (ko)
DE (1) DE69005827T2 (ko)
DK (1) DK0487615T3 (ko)
ES (1) ES2062551T3 (ko)
WO (1) WO1991002704A1 (ko)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5443813A (en) * 1991-06-06 1995-08-22 Associated Universities, Inc. Loading and conjugating cavity biostructures
US20060003163A1 (en) * 1996-11-16 2006-01-05 Nanomagnetics Limited Magnetic fluid
US6713173B2 (en) 1996-11-16 2004-03-30 Nanomagnetics Limited Magnetizable device
US6815063B1 (en) 1996-11-16 2004-11-09 Nanomagnetics, Ltd. Magnetic fluid
US6986942B1 (en) 1996-11-16 2006-01-17 Nanomagnetics Limited Microwave absorbing structure
GB2319253A (en) 1996-11-16 1998-05-20 Eric Leigh Mayes Composition, for use in a device, comprising a magnetic layer of domain-separated magnetic particles
US6180389B1 (en) * 1997-01-03 2001-01-30 The Research And Development Institute, Inc. Virion-constrained nanoparticles comprising a plant virion coat protein shell and encapsulated guest molecules
WO1998032902A1 (en) * 1997-01-22 1998-07-30 Ester Guy R Method of manufacturing crystalline particles on a support or a substrate
US6514453B2 (en) * 1997-10-21 2003-02-04 Nanoproducts Corporation Thermal sensors prepared from nanostructureed powders
AU4116401A (en) 2000-03-16 2001-09-24 Matsushita Electric Industrial Co., Ltd. Nucleotide detector, process for producing the same and process for forming fineparticle membrane
DE10042023C2 (de) * 2000-08-08 2003-04-10 Biognostic Ag Kapseln, die feste Teilchen signalerzeugender Substanzen einkapseln, und deren Verwendung bei Bioassays zum Nachweis von Zielmolekülen in einer Probe
US7033613B2 (en) 2001-05-14 2006-04-25 Matsushita Electric Industrial Co., Ltd. Recombinant cage-like protein, method for producing the same, precious metal-recombinant cage-like protein complex, method for producing the same and recombinant DNA
JP3588602B2 (ja) * 2001-10-01 2004-11-17 松下電器産業株式会社 コバルト−タンパク質複合体の作製方法
US7282710B1 (en) 2002-01-02 2007-10-16 International Business Machines Corporation Scanning probe microscopy tips composed of nanoparticles and methods to form same
US20040028694A1 (en) * 2002-02-01 2004-02-12 Young Mark J. Novel nanoparticles and use thereof
US6897650B2 (en) * 2002-02-11 2005-05-24 International Business Machines Corporation Magnetic-field sensor device
CA2485363C (en) * 2002-05-10 2014-10-28 New Century Pharmaceuticals, Inc. Ferritin fusion proteins for use in vaccines and other applications
WO2003096990A2 (en) * 2002-05-17 2003-11-27 Montana State University Protein cages for the delivery of medical imaging and therapy
JP3683265B2 (ja) * 2002-05-28 2005-08-17 松下電器産業株式会社 ナノ粒子の製造方法及び該製造方法によって製造されたナノ粒子
JP3703479B2 (ja) * 2002-09-20 2005-10-05 松下電器産業株式会社 ナノ粒子の製造方法及び該製造方法によって製造されたナノ粒子
GB2393729A (en) * 2002-10-04 2004-04-07 Nanomagnetics Ltd Semiconductor nanoparticles
WO2004088313A1 (en) * 2003-04-02 2004-10-14 Tero Soukka Nanoparticle for bioaffinity assays
FI20030615A0 (fi) * 2003-04-24 2003-04-24 Marko Virta Nanopartikkeli bioaffiniteettimäärityksiin
US6972095B1 (en) 2003-05-07 2005-12-06 Electric Power Research Institute Magnetic molecules: a process utilizing functionalized magnetic ferritins for the selective removal of contaminants from solution by magnetic filtration
EP1571198A1 (en) * 2004-03-02 2005-09-07 Dalli-Werke GmbH & Co. KG. Polymer bound manganese compounds in cleaning compositions
WO2006132050A1 (ja) 2005-06-07 2006-12-14 Matsushita Electric Industrial Co., Ltd. 酸化亜鉛－タンパク質複合体の製造方法
US20100021391A1 (en) * 2006-07-14 2010-01-28 Montana State University Novel nanoparticles for biofilm targeting
JP4149503B2 (ja) * 2006-12-07 2008-09-10 松下電器産業株式会社 フェリチンを基板上に二次元配列させる方法
JP4149504B2 (ja) * 2006-12-07 2008-09-10 松下電器産業株式会社 フェリチンを基板上に二次元配列させる方法
JP5325427B2 (ja) * 2008-02-20 2013-10-23 株式会社Ｉｈｉ 磁性を有する薬剤
DE102008023228A1 (de) 2008-05-08 2009-11-19 Technische Universität Dresden Nanopartikel zur selektiven Gewebetherapie, Verfahren zu deren Herstellung und deren Verwendung in der Gewebetherapie
JP2011025116A (ja) * 2009-07-22 2011-02-10 Okayama Univ 金属類回収装置
JP5624735B2 (ja) * 2009-07-22 2014-11-12 国立大学法人岡山大学 フィルター
US8945391B2 (en) * 2009-08-03 2015-02-03 National Institute For Materials Science Organic polymers-separation membrane filter, and organic polymers-separation method
US20120020879A1 (en) * 2010-07-22 2012-01-26 Brigham Young University Process, composition and method for anion deposition into ferritin for therapeutic and other use
JP6100762B2 (ja) 2011-06-02 2017-03-22 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 膜で被包されたナノ粒子および使用方法
WO2015021390A2 (en) 2013-08-08 2015-02-12 The Regents Of The University Of California Nanoparticles leverage biological membranes to target pathogens for disease treatment and diagnosis
CN106163504B (zh) 2014-03-20 2021-02-09 加利福尼亚大学董事会 水凝胶毒素-吸收或结合纳米颗粒
WO2015187502A1 (en) 2014-06-02 2015-12-10 Cellics Therapeutics, Inc. Use of nanoparticles coated with red blood cell membranes to treat hemolytic diseases and disorders
WO2016109306A1 (en) 2015-01-02 2016-07-07 Cellics Therapeutics, Inc. Use of nanoparticles coated with red blood cell membranes to enable blood transfusion
KR101523924B1 (ko) * 2015-02-13 2015-06-01 한국지질자원연구원 철단백질을 이용한 수용성 금속 나노입자의 합성 장치 및 이를 이용해 제조된 수용성 금속 나노입자
US10610493B2 (en) 2015-04-29 2020-04-07 The Regents Of The University Of California Detoxification using nanoparticles
KR102225790B1 (ko) * 2016-07-08 2021-03-11 나가세 상교오 가부시키가이샤 금속 내포 바구니형 단백질의 제조 방법
JP7312429B2 (ja) * 2019-05-23 2023-07-21 国立大学法人 奈良先端科学技術大学院大学 ゲル組成物及びゲル乾燥物
WO2020239809A1 (en) * 2019-05-28 2020-12-03 Previpharma Consulting Gmbh Method for preparing iron-depleted ferritin and use thereof
JP7754614B2 (ja) * 2019-09-03 2025-10-15 株式会社 東北テクノアーチ フェリチン用リンス液
WO2026027779A1 (en) 2024-08-02 2026-02-05 Previpharma Gmbh Extraction and purification of (apo)ferritin from blood plasma and plasma fractions

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3937668A (en) * 1970-07-15 1976-02-10 Ilse Zolle Method for incorporating substances into protein microspheres
DE2656317C2 (de) * 1976-12-11 1986-06-19 Kernforschungsanlage Jülich GmbH, 5170 Jülich Verfahren zur Herstellung einer Suspension von beladenen Erythrocyten
SE443282B (sv) * 1981-06-25 1986-02-24 Alfa Laval Ab Fettprodukt som er bredbar vid kylskapstemperatur samt forfarande for framstellning derav
JPS61174103A (ja) * 1985-01-23 1986-08-05 Shokubai Kasei Kogyo Kk 金属酸化物からなる多孔質真球状微粒子粉末の製造法
EP0214308B1 (en) * 1985-03-05 1993-07-28 Idemitsu Kosan Company Limited Method for preparing super-fine spherical particles of metal oxide
US4778671A (en) * 1986-07-14 1988-10-18 Corning Glass Works Preparation of unagglomerated metal oxide particles with uniform particle size
US5141634A (en) * 1988-02-03 1992-08-25 Regents Of The University Of Minnesota High stability porous zirconium oxide spherules
US5108597A (en) * 1990-03-22 1992-04-28 Regents Of The University Of Minnesota Carbon-clad zirconium oxide particles
US5173454A (en) * 1992-01-09 1992-12-22 Corning Incorporated Nanocrystalline materials

Also Published As

Publication number Publication date
ES2062551T3 (es) 1994-12-16
WO1991002704A1 (en) 1991-03-07
ATE99656T1 (de) 1994-01-15
EP0487615B1 (en) 1994-01-05
DE69005827T2 (de) 1994-07-28
DE69005827D1 (de) 1994-02-17
US5358722A (en) 1994-10-25
AU641936B2 (en) 1993-10-07
JPH04507255A (ja) 1992-12-17
DK0487615T3 (da) 1994-03-14
EP0487615A1 (en) 1992-06-03
CA2064069A1 (en) 1991-02-19
US5304382A (en) 1994-04-19
AU6296790A (en) 1991-04-03
KR950002917B1 (ko) 1995-03-28

Similar Documents

Publication Publication Date Title
KR920703473A (ko) 페리틴 유사체
KR890009804A (ko) 안정화된 지르코니아, 이의 제조방법 및 세라믹 조성물에서의 용도
JPS6486975A (en) Preparation of calcium phosphate compound coated composite material
KR870000101A (ko) 은 함유 촉매 및 산화에틸렌과 이 촉매의 제조방법
DE2313760C3 (de) Hochtransparenter Körper aus Aluminiumoxyd und Verfahren zu seiner Herstellung
JPS54114445A (en) Low hydrogen type coated arc welding rod
DE3216863A1 (de) Magnetisches aufzeichnungsmaterial
DE69008440T2 (de) Verfahren zur Herstellung keramischer und zusammengesetzter keramischer Körper.
US6224944B1 (en) Method of protecting a surface
KR900001598A (ko) 산화알루미늄 응집체의 제조방법 및 수득한 응집체
ES433778A1 (es) Metodo mejorado de inhibir la perdida de velocidad de seca- do, por envejecimiento, de composiciones de recubrimiento superficial que contienen agentes secantes de sales metali- cas.
GB1508003A (en) Expandable polymer compositions comprising particles of a polymer derived from ethylenically unsaturated monomers
RU94046350A (ru) Способ получения свободно-текучих частиц нитрата аммония, покрытые частицы нитрата аммония
DE3703206A1 (de) Waermedaemmende trennwand und verfahren zur herstellung derselben
DE69603122T2 (de) Aluminiumoxidsol mit hoher Konzentration und niedriger Viskosität
Lynch et al. The microstructure of single-crystal titanium diboride
ES391483A1 (es) Un procedimiento para controlar la acumulacion de iones in-deseables en un circuito de instalacion de cinc electroliti-co.
PL16240B1 (pl) Sposób otrzymywania mieszanin weglanów wapniowców, stosowanych do wyrobu katod tlenkowych.
US2963450A (en) Filament coating composition
DE2046482C3 (de) Verfahren zum Konservieren von Steinen
JPS54121248A (en) Coated arc welding rod for low hydrogen system
Inaba Wettability of Solid Surface. VI. The Effects of Metallic Cations on Stearic Acid Built-up Film
JPS57118019A (en) Manufacture of miio-m2iiio3 powder
JPS5256136A (en) Coating composition
DE1131813B (de) Verfahren zum Aufbringen duenner emissions-faehiger Schichten auf Kathodentraeger elektrischer Entladungsgefaesse

Legal Events

Date Code Title Description
A201 Request for examination
PA0105 International application

St.27 status event code: A-0-1-A10-A15-nap-PA0105

PA0201 Request for examination

St.27 status event code: A-1-2-D10-D11-exm-PA0201

R17-X000 Change to representative recorded

St.27 status event code: A-3-3-R10-R17-oth-X000

PG1501 Laying open of application

St.27 status event code: A-1-1-Q10-Q12-nap-PG1501

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

St.27 status event code: A-1-2-D10-D21-exm-PE0902

T11-X000 Administrative time limit extension requested

St.27 status event code: U-3-3-T10-T11-oth-X000

T11-X000 Administrative time limit extension requested

St.27 status event code: U-3-3-T10-T11-oth-X000

T11-X000 Administrative time limit extension requested

St.27 status event code: U-3-3-T10-T11-oth-X000

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

G160 Decision to publish patent application
PG1605 Publication of application before grant of patent

St.27 status event code: A-2-2-Q10-Q13-nap-PG1605

E701 Decision to grant or registration of patent right
PE0701 Decision of registration

St.27 status event code: A-1-2-D10-D22-exm-PE0701

GRNT Written decision to grant
PR0701 Registration of establishment

St.27 status event code: A-2-4-F10-F11-exm-PR0701

PR1002 Payment of registration fee

St.27 status event code: A-2-2-U10-U12-oth-PR1002

Fee payment year number: 1

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 4

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 5

FPAY Annual fee payment

Payment date: 20000322

Year of fee payment: 6

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 6

R18-X000 Changes to party contact information recorded

St.27 status event code: A-5-5-R10-R18-oth-X000

R18-X000 Changes to party contact information recorded

St.27 status event code: A-5-5-R10-R18-oth-X000

LAPS Lapse due to unpaid annual fee
PC1903 Unpaid annual fee

St.27 status event code: A-4-4-U10-U13-oth-PC1903

Not in force date: 20010329

Payment event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

PC1903 Unpaid annual fee

St.27 status event code: N-4-6-H10-H13-oth-PC1903

Ip right cessation event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

Not in force date: 20010329

PN2301 Change of applicant

St.27 status event code: A-5-5-R10-R13-asn-PN2301

St.27 status event code: A-5-5-R10-R11-asn-PN2301

R18-X000 Changes to party contact information recorded

St.27 status event code: A-5-5-R10-R18-oth-X000

R18-X000 Changes to party contact information recorded

St.27 status event code: A-5-5-R10-R18-oth-X000

R18-X000 Changes to party contact information recorded

St.27 status event code: A-5-5-R10-R18-oth-X000

R18-X000 Changes to party contact information recorded

St.27 status event code: A-5-5-R10-R18-oth-X000

R18-X000 Changes to party contact information recorded

St.27 status event code: A-5-5-R10-R18-oth-X000

P22-X000 Classification modified

St.27 status event code: A-4-4-P10-P22-nap-X000