KR940001902A - 쓴 약제의 맛-차단 조성물 - Google Patents

쓴 약제의 맛-차단 조성물 Download PDF

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KR940001902A
KR940001902A KR1019930014564A KR930014564A KR940001902A KR 940001902 A KR940001902 A KR 940001902A KR 1019930014564 A KR1019930014564 A KR 1019930014564A KR 930014564 A KR930014564 A KR 930014564A KR 940001902 A KR940001902 A KR 940001902A
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composition
bitter
alkaline earth
bacterial infection
pharmaceutically acceptable
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KR100242399B1 (ko
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에스.카타니아 조셉
디. 존슨 알톤
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알렌 제이. 스피겔
화이자 인코포레이티드
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/01—Hydrocarbons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Zoology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)

Abstract

본 발명은 쓴 약제, 맛-차단 성분 및 약제적으로 허용 가능한 담체로 이루어진, 쓴맛이 감소된 약학 조성물에 관한 것이다.
상기 쓴맛-차단성분은 알칼리 토 산화물, 알칼리 토수산화물 또는 알칼리 수산화물이며, 이는 약제의 활성을 방해하지 않는다.

Description

쓴 약제의 맛-차단 조성물
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (15)

  1. 쓴 약제 ; 알칼리 토 산화물 및 알칼리 토 수산화물로 이루어 진 그룹 중에서 선택된 염기성 화합물 ; 및 약학적으로 허용가능한 담체를 포함하는, 쓴맛이 감소된 약학 조성물.
  2. 제1항에 있어서, 상기 염기성 화합물이 알칼리 토 산화물인 조성물
  3. 제2항에 있어서, 상기 쓴 약제가 아자라이드인 조성물.
  4. 제3항에 있어서, 상기 알칼리 토 산화물이 산화 마그네슘인 조성물.
  5. 제4항에 있어서, 상기 아자라이드가 아지쓰로마이신인 조성물.
  6. 제1항에 있어서, 알돈산 또는 그의 약학적으로 허용가능한 염을 추가로 포항하는 조성물.
  7. 제6항에 있어서, 상기 알돈산이 약학적으로 허용가능한 염으로서 존재하는 조성물.
  8. 제7항에 있어서, 상기 알돈산화염이 글루콘산 칼슘인 조성물.
  9. 제8항에 있어서, 상기 염기성 화합물이 알칼리 토 산화물인 조성물.
  10. 제9항에 있언서, 상기 쓴 약제가 아자라이드인 조성물.
  11. 제10항에 있어서, 상기 알칼리 토 산화물이 산화 마그네슘인 조성물.
  12. 제11항에 있어서, 상기 아자라이드가 아지쓰로마이신인 조성물.
  13. 쓴 약제를 제1항에 따른 약락 조성물로서 배합함을 포함하는, 상기 쓴 약제의 쓴맛을 감소시키는 방법.
  14. 세균감염으로 고통받는 포유동물에게 항균 유효량의 제3항에 따른 약학 조성물을 투여함을 포항하는, 상기 포유동물의 세균 감염 치료방법.
  15. 세균감염으로 고통받는 포유동물에게 항균 유효량의 제10항에 따른 약학 조성물을 투여함을 포함하는, 상기 포유동물의 세균 감염 치료방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019930014564A 1992-07-30 1993-07-29 쓴 약제의 맛-차단 조성물 Expired - Fee Related KR100242399B1 (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US92226292A 1992-07-30 1992-07-30
US922,262 1992-07-30
JP922,262 1992-07-30
JP93-083225 1993-04-09

Publications (2)

Publication Number Publication Date
KR940001902A true KR940001902A (ko) 1994-02-16
KR100242399B1 KR100242399B1 (ko) 2000-03-02

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Country Link
US (1) US5633006A (ko)
EP (1) EP0582396B1 (ko)
JP (1) JP2685403B2 (ko)
KR (1) KR100242399B1 (ko)
CN (1) CN1030964C (ko)
AT (1) ATE198421T1 (ko)
AU (1) AU655892B2 (ko)
CA (1) CA2101466C (ko)
CZ (1) CZ285057B6 (ko)
DE (1) DE69329810T2 (ko)
DK (1) DK0582396T3 (ko)
EG (1) EG20385A (ko)
ES (1) ES2153836T3 (ko)
FI (1) FI933404A7 (ko)
GR (1) GR3035426T3 (ko)
HR (1) HRP931049B1 (ko)
HU (1) HU221682B1 (ko)
IL (1) IL106451A (ko)
MX (1) MX9304577A (ko)
MY (1) MY110581A (ko)
NO (1) NO308023B1 (ko)
NZ (1) NZ248280A (ko)
PL (1) PL174795B1 (ko)
PT (1) PT582396E (ko)
RU (1) RU2126257C1 (ko)
SK (1) SK280194B6 (ko)
TW (1) TW271400B (ko)
YU (1) YU52593A (ko)
ZA (1) ZA935475B (ko)

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KR100809911B1 (ko) * 1999-02-18 2008-03-06 후소카가쿠코교 가부시키가이샤 마스킹제

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YU52593A (sh) 1996-05-20
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CA2101466C (en) 2000-06-06
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NO308023B1 (no) 2000-07-10
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CN1083728A (zh) 1994-03-16
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CA2101466A1 (en) 1994-01-31
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FI933404A0 (fi) 1993-07-29
RU2126257C1 (ru) 1999-02-20
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ZA935475B (en) 1995-01-29
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HU9302213D0 (en) 1993-10-28
PT582396E (pt) 2001-04-30
IL106451A0 (en) 1993-11-15
EP0582396A1 (en) 1994-02-09
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NO932736D0 (no) 1993-07-29
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AU655892B2 (en) 1995-01-12
EG20385A (en) 1999-02-28
PL174795B1 (pl) 1998-09-30
TW271400B (ko) 1996-03-01
NZ248280A (en) 1995-07-26
DE69329810D1 (de) 2001-02-08
ATE198421T1 (de) 2001-01-15
US5633006A (en) 1997-05-27
MY110581A (en) 1998-08-29
ES2153836T3 (es) 2001-03-16
CZ285057B6 (cs) 1999-05-12
KR100242399B1 (ko) 2000-03-02
GR3035426T3 (en) 2001-05-31
HU221682B1 (hu) 2002-12-28
NO932736L (no) 1994-01-31
AU4426193A (en) 1994-04-28
CN1030964C (zh) 1996-02-14

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