LT2704703T - Transderminės ibuprofeno kompozicijos ir jų naudojimo būdai - Google Patents

Transderminės ibuprofeno kompozicijos ir jų naudojimo būdai

Info

Publication number
LT2704703T
LT2704703T LT12779275T LT12779275T LT2704703T LT 2704703 T LT2704703 T LT 2704703T LT 12779275 T LT12779275 T LT 12779275T LT 12779275 T LT12779275 T LT 12779275T LT 2704703 T LT2704703 T LT 2704703T
Authority
LT
Lithuania
Prior art keywords
ibuprophene
transdermal
compositions
transdermal ibuprophene
ibuprophene compositions
Prior art date
Application number
LT12779275T
Other languages
English (en)
Inventor
Haigang Chen
Gareth Winckle
Christopher Riley
Original Assignee
Aponia Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47108054&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LT2704703(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Aponia Laboratories Inc filed Critical Aponia Laboratories Inc
Publication of LT2704703T publication Critical patent/LT2704703T/lt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Immunology (AREA)
  • Dispersion Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
LT12779275T 2011-05-03 2012-05-03 Transderminės ibuprofeno kompozicijos ir jų naudojimo būdai LT2704703T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161482058P 2011-05-03 2011-05-03
PCT/US2012/036366 WO2012151427A1 (en) 2011-05-03 2012-05-03 Transdermal compositions of ibuprofen and methods of use thereof

Publications (1)

Publication Number Publication Date
LT2704703T true LT2704703T (lt) 2019-12-10

Family

ID=47108054

Family Applications (1)

Application Number Title Priority Date Filing Date
LT12779275T LT2704703T (lt) 2011-05-03 2012-05-03 Transderminės ibuprofeno kompozicijos ir jų naudojimo būdai

Country Status (26)

Country Link
US (7) US9205041B2 (lt)
EP (2) EP2704703B1 (lt)
JP (1) JP5989095B2 (lt)
KR (1) KR101926211B1 (lt)
CN (1) CN103717213B (lt)
AU (3) AU2012250664B2 (lt)
BR (1) BR112013028435A2 (lt)
CA (1) CA2835062C (lt)
CL (1) CL2013003163A1 (lt)
CO (1) CO6862148A2 (lt)
CY (1) CY1122273T1 (lt)
DK (1) DK2704703T3 (lt)
EA (1) EA026697B1 (lt)
ES (1) ES2749323T3 (lt)
HR (1) HRP20191806T1 (lt)
HU (1) HUE046750T2 (lt)
LT (1) LT2704703T (lt)
ME (1) ME03540B (lt)
MX (1) MX365427B (lt)
PE (2) PE20140936A1 (lt)
PL (1) PL2704703T3 (lt)
PT (1) PT2704703T (lt)
RS (1) RS59484B1 (lt)
SI (1) SI2704703T1 (lt)
SM (1) SMT201900595T1 (lt)
WO (1) WO2012151427A1 (lt)

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UA119324C2 (uk) * 2013-04-02 2019-06-10 Теміс Медікер Лімітед Композиції фармацевтично активних речовин, що містять моноетиловий ефір діетиленгліколю або інші алкільні похідні
JP6632810B2 (ja) * 2015-03-31 2020-01-22 小林製薬株式会社 外用医薬組成物
WO2017027778A1 (en) * 2015-08-13 2017-02-16 Temple University-Of The Commonwealth System Of Higher Education Calcium alginate dosage formulations, and methods of making and using thereof
KR20190003535A (ko) * 2016-03-31 2019-01-09 스마테크 토피칼, 인코포레이티드 전달 시스템
GB201609968D0 (en) * 2016-06-07 2016-07-20 Futura Medical Dev Ltd Topical pharmaceutical formulation
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WO2018090149A1 (en) * 2016-11-21 2018-05-24 Vivier Canada Inc. Putrescine slow-release topical formulations
GB201706969D0 (en) * 2017-05-02 2017-06-14 Medherant Ltd Formulation
JP7025129B2 (ja) * 2017-05-17 2022-02-24 小林製薬株式会社 筋痙攣治療剤
US12042487B2 (en) 2018-11-16 2024-07-23 Arcutis Biotherapeutics, Inc. Method for reducing side effects from administration of phosphodiesterase-4 inhibitors
US20210161870A1 (en) 2017-06-07 2021-06-03 Arcutis Biotherapeutics, Inc. Roflumilast formulations with an improved pharmacokinetic profile
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US11534493B2 (en) * 2017-09-22 2022-12-27 Arcutis Biotherapeutics, Inc. Pharmaceutical compositions of roflumilast in aqueous blends of water-miscible, pharmaceutically acceptable solvents
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KR20190101140A (ko) * 2018-02-22 2019-08-30 동아제약 주식회사 비스테로이드성 소염진통 활성성분을 함유하는 필름 형성 약제학적 조성물
JP7492918B2 (ja) 2018-06-04 2024-05-30 アーキュティス・バイオセラピューティクス・インコーポレーテッド ロフルミラスト皮膚浸透ラグタイムを改善する方法及び配合物
CN112206222A (zh) * 2018-11-09 2021-01-12 北京德默高科医药技术有限公司 含有布洛芬结构类似物的多层经皮给药系统
US20220378729A1 (en) 2019-11-06 2022-12-01 Smartech Topical, Inc. Topical formulations of cyclooxygenase inhibitors and their use
EP4458414A3 (en) 2020-12-04 2025-01-01 Arcutis Biotherapeutics, Inc. Topical roflumilast formulation having antifungal properties
EP4308088B1 (en) 2021-11-08 2025-03-12 Weiyong Li Transdermal drug delivery system for delivering a drug to a patient
CN118765194A (zh) 2021-12-28 2024-10-11 阿尔库缇斯生物疗法股份有限公司 局部罗氟司特气溶胶泡沫
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Also Published As

Publication number Publication date
US20210045999A1 (en) 2021-02-18
HRP20191806T1 (hr) 2020-01-10
SI2704703T1 (sl) 2019-12-31
US20180125779A1 (en) 2018-05-10
JP2014513132A (ja) 2014-05-29
RS59484B1 (sr) 2019-12-31
PE20140936A1 (es) 2014-08-06
NZ618259A (en) 2016-02-26
ES2749323T3 (es) 2020-03-19
US20230248640A1 (en) 2023-08-10
PE20180399A1 (es) 2018-02-28
CA2835062C (en) 2019-08-13
EP2704703A4 (en) 2014-12-03
AU2012250664B2 (en) 2017-04-20
BR112013028435A2 (pt) 2017-01-24
US20160331678A1 (en) 2016-11-17
AU2019203188A1 (en) 2019-05-30
CY1122273T1 (el) 2020-11-25
US10821071B2 (en) 2020-11-03
EP2704703A1 (en) 2014-03-12
CN103717213B (zh) 2016-11-09
MX2013012832A (es) 2015-01-22
WO2012151427A1 (en) 2012-11-08
HUE046750T2 (hu) 2020-03-30
AU2012250664A1 (en) 2013-12-19
US9205041B2 (en) 2015-12-08
US20130005816A1 (en) 2013-01-03
EP2704703B1 (en) 2019-07-24
DK2704703T3 (da) 2019-10-14
PT2704703T (pt) 2019-10-25
EP3560485A1 (en) 2019-10-30
AU2017204878A1 (en) 2017-08-03
US9849080B2 (en) 2017-12-26
US20240108569A1 (en) 2024-04-04
ME03540B (me) 2020-07-20
US20220387301A1 (en) 2022-12-08
CL2013003163A1 (es) 2014-07-04
CA2835062A1 (en) 2012-11-08
SMT201900595T1 (it) 2019-11-13
US11419814B2 (en) 2022-08-23
KR101926211B1 (ko) 2019-02-26
JP5989095B2 (ja) 2016-09-07
EA026697B1 (ru) 2017-05-31
EA201391623A1 (ru) 2014-06-30
NZ703779A (en) 2016-10-28
MX365427B (es) 2019-06-03
KR20140041504A (ko) 2014-04-04
CO6862148A2 (es) 2014-02-10
PL2704703T3 (pl) 2020-03-31
CN103717213A (zh) 2014-04-09

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