LT2709445T - Kiaulių reprodukcinio ir kvėpavimo sindromo virusui atsparūs gyvūnai - Google Patents

Kiaulių reprodukcinio ir kvėpavimo sindromo virusui atsparūs gyvūnai

Info

Publication number: LT2709445T
Authority: LT; Lithuania
Prior art keywords: pigs; virus; representative; respiratory syndrome; animals
Prior art date: 2011-05-16

Application number

LTEP12785983.3T

Other languages

English (en)

Inventor

Randall S. Prather

Kevin D. Wells

Kristin M. Whitworth

Original Assignee

The Curators Of The University Of Missouri

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2011-05-16

Filing date

2012-05-16

Publication date

2018-11-12

2012-05-16 Application filed by The Curators Of The University Of Missouri filed Critical The Curators Of The University Of Missouri

2018-11-12 Publication of LT2709445T publication Critical patent/LT2709445T/lt

Links

241001465754 Metazoa Species 0.000 title 1
241000282887 Suidae Species 0.000 title 1
241000700605 Viruses Species 0.000 title 1
230000000241 respiratory effect Effects 0.000 title 1
208000011580 syndromic disease Diseases 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A01K67/0275—Genetically modified vertebrates, e.g. transgenic
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A01K67/0275—Genetically modified vertebrates, e.g. transgenic
- A01K67/0276—Knock-out vertebrates
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/07—Animals genetically altered by homologous recombination
- A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/15—Animals comprising multiple alterations of the genome, by transgenesis or homologous recombination, e.g. obtained by cross-breeding
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/108—Swine
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/02—Animal zootechnically ameliorated
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/7056—Lectin superfamily, e.g. CD23, CD72
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70596—Molecules with a "CD"-designation not provided for elsewhere
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/80—Vectors containing sites for inducing double-stranded breaks, e.g. meganuclease restriction sites

Landscapes

Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Genetics & Genomics (AREA)
Zoology (AREA)
Biotechnology (AREA)
Environmental Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical & Material Sciences (AREA)
Biomedical Technology (AREA)
Wood Science & Technology (AREA)
Organic Chemistry (AREA)
General Engineering & Computer Science (AREA)
Animal Husbandry (AREA)
Biodiversity & Conservation Biology (AREA)
Animal Behavior & Ethology (AREA)
Microbiology (AREA)
Biochemistry (AREA)
Physics & Mathematics (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Plant Pathology (AREA)
Cell Biology (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

LTEP12785983.3T 2011-05-16 2012-05-16 Kiaulių reprodukcinio ir kvėpavimo sindromo virusui atsparūs gyvūnai LT2709445T (lt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US201161519076P	2011-05-16	2011-05-16
PCT/US2012/038193 WO2012158828A1 (en)	2011-05-16	2012-05-16	Porcine reproductive and respiratory syndrome virus resistant animals

Publications (1)

Publication Number	Publication Date
LT2709445T true LT2709445T (lt)	2018-11-12

Family

ID=47177326

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
LTEP12785983.3T LT2709445T (lt)	2011-05-16	2012-05-16	Kiaulių reprodukcinio ir kvėpavimo sindromo virusui atsparūs gyvūnai

Country Status (22)

Country	Link
US (6)	US9820475B2 (lt)
EP (2)	EP3420813A1 (lt)
JP (6)	JP2014519323A (lt)
KR (6)	KR102807016B1 (lt)
CN (3)	CN103687482A (lt)
AU (5)	AU2012255744A1 (lt)
BR (1)	BR112013029498A8 (lt)
CA (2)	CA3184311A1 (lt)
CY (1)	CY1120890T1 (lt)
DK (1)	DK2709445T3 (lt)
ES (1)	ES2691618T3 (lt)
HK (1)	HK1215282A1 (lt)
HR (1)	HRP20181729T1 (lt)
HU (1)	HUE039793T2 (lt)
LT (1)	LT2709445T (lt)
MX (2)	MX383372B (lt)
PH (2)	PH12020500244A1 (lt)
PL (1)	PL2709445T3 (lt)
PT (1)	PT2709445T (lt)
RU (1)	RU2644673C2 (lt)
SI (1)	SI2709445T1 (lt)
WO (1)	WO2012158828A1 (lt)

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GB201313235D0 (en)	2013-07-24	2013-09-04	Univ Edinburgh	Antiviral Compositions Methods and Animals
WO2015153647A1 (en) *	2014-03-31	2015-10-08	Mice With Horns, Llc	Method of preventing or reducing virus transmission in animals
CN104593422A (zh) *	2015-01-08	2015-05-06	中国农业大学	一种抗蓝耳病克隆猪的制备方法
JP6929527B2 (ja) *	2015-03-04	2021-09-01	株式会社ポル・メド・テック	安定した表現型を示す疾患モデルブタおよびその作製方法
KR20250016515A (ko) *	2015-08-06	2025-02-03	더 큐레이터스 오브 더 유니버시티 오브 미주리	변형된 cd163 유전자를 갖는 병원균-내성 동물
FI3331355T3 (fi)	2015-08-06	2024-06-17	Univ Missouri	Sikojen lisääntymishäiriö- ja keuhkotulehdusoireyhtymävirukselle (PRRSV) resistentti sika ja soluja, joilla on muokattuja CD163-geenejä
GB201617559D0 (en)	2016-10-17	2016-11-30	University Court Of The University Of Edinburgh The	Swine comprising modified cd163 and associated methods
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CN107937345B (zh) *	2017-11-16	2019-01-29	山东蓝思种业股份有限公司	一种制备同时敲除cd163基因和cd13基因的猪成纤维细胞的方法
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US11160260B2 (en)	2018-04-17	2021-11-02	The Curators Of The University Of Missouri	Methods for protecting porcine fetuses from infection with porcine reproductive and respiratory syndrome virus (PRRSV)
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JP2023525263A (ja)	2020-05-05	2023-06-15	ジーナスピーエルシー	Ｃｄ１６３不活化のターゲティングにより、ブタ種の健康状態を改善するための方法
ES3064029T3 (en) *	2021-01-05	2026-04-22	Public Univ Corporation Yokohama City Univ	Biomarker for determining fertility, and determining method using same

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2012
- 2012-05-16 KR KR1020247001725A patent/KR102807016B1/ko active Active
- 2012-05-16 HR HRP20181729TT patent/HRP20181729T1/hr unknown
- 2012-05-16 PH PH1/2020/500244A patent/PH12020500244A1/en unknown
- 2012-05-16 KR KR1020237029748A patent/KR102627319B1/ko active Active
- 2012-05-16 WO PCT/US2012/038193 patent/WO2012158828A1/en not_active Ceased
- 2012-05-16 MX MX2018008377A patent/MX383372B/es unknown
- 2012-05-16 MX MX2013013427A patent/MX357421B/es active IP Right Grant
- 2012-05-16 LT LTEP12785983.3T patent/LT2709445T/lt unknown
- 2012-05-16 PL PL12785983T patent/PL2709445T3/pl unknown
- 2012-05-16 CA CA3184311A patent/CA3184311A1/en active Pending
- 2012-05-16 HU HUE12785983A patent/HUE039793T2/hu unknown
- 2012-05-16 ES ES12785983.3T patent/ES2691618T3/es active Active
- 2012-05-16 CA CA2836288A patent/CA2836288A1/en active Pending
- 2012-05-16 SI SI201231423T patent/SI2709445T1/sl unknown
- 2012-05-16 AU AU2012255744A patent/AU2012255744A1/en not_active Abandoned
- 2012-05-16 CN CN201280023487.4A patent/CN103687482A/zh active Pending
- 2012-05-16 KR KR1020137033359A patent/KR20140034229A/ko not_active Ceased
- 2012-05-16 CN CN201510463471.0A patent/CN105112450A/zh active Pending
- 2012-05-16 BR BR112013029498A patent/BR112013029498A8/pt not_active Application Discontinuation
- 2012-05-16 EP EP18189039.3A patent/EP3420813A1/en active Pending
- 2012-05-16 CN CN202010588447.0A patent/CN111593025A/zh active Pending
- 2012-05-16 KR KR1020227026347A patent/KR102574897B1/ko active Active
- 2012-05-16 KR KR1020257015124A patent/KR20250073511A/ko active Pending
- 2012-05-16 RU RU2013155677A patent/RU2644673C2/ru active
- 2012-05-16 PH PH1/2013/502360A patent/PH12013502360A1/en unknown
- 2012-05-16 KR KR1020207015089A patent/KR102428306B1/ko active Active
- 2012-05-16 EP EP12785983.3A patent/EP2709445B1/en active Active
- 2012-05-16 DK DK12785983.3T patent/DK2709445T3/en active
- 2012-05-16 JP JP2014511498A patent/JP2014519323A/ja active Pending
- 2012-05-16 PT PT12785983T patent/PT2709445T/pt unknown
- 2012-05-16 US US14/117,943 patent/US9820475B2/en active Active
2016
- 2016-03-21 HK HK16103259.2A patent/HK1215282A1/zh unknown
2017
- 2017-04-19 AU AU2017202540A patent/AU2017202540B2/en active Active
- 2017-05-09 JP JP2017092768A patent/JP6970525B2/ja active Active
- 2017-10-13 US US15/783,417 patent/US10080353B2/en active Active
2018
- 2018-08-24 US US16/111,631 patent/US10405526B2/en active Active
- 2018-11-02 AU AU2018256670A patent/AU2018256670B2/en active Active
- 2018-11-07 CY CY181101169T patent/CY1120890T1/el unknown
2019
- 2019-07-04 JP JP2019125475A patent/JP2019193660A/ja not_active Withdrawn
- 2019-08-30 US US16/556,878 patent/US11019809B2/en active Active
2020
- 2020-12-24 AU AU2020294305A patent/AU2020294305A1/en not_active Abandoned
2021
- 2021-04-28 US US17/242,963 patent/US12527305B2/en active Active
2022
- 2022-03-16 JP JP2022041628A patent/JP2022081637A/ja not_active Withdrawn
2023
- 2023-08-22 AU AU2023219858A patent/AU2023219858A1/en not_active Abandoned
2024
- 2024-03-06 JP JP2024033472A patent/JP2024069309A/ja active Pending
- 2024-04-19 US US18/640,282 patent/US20240284884A1/en active Pending
2026
- 2026-01-08 JP JP2026001964A patent/JP2026065056A/ja active Pending

Also Published As

Publication number	Publication date
US20180027783A1 (en)	2018-02-01
HK1215282A1 (zh)	2016-08-19
RU2013155677A (ru)	2015-06-27
AU2012255744A1 (en)	2014-01-09
BR112013029498A8 (pt)	2017-02-21
HUE039793T2 (hu)	2019-02-28
SI2709445T1 (sl)	2018-11-30
EP2709445B1 (en)	2018-10-03
KR20250073511A (ko)	2025-05-27
HRP20181729T1 (hr)	2018-12-28
KR102574897B1 (ko)	2023-09-06
US20210259219A1 (en)	2021-08-26
US20240284884A1 (en)	2024-08-29
PT2709445T (pt)	2018-11-27
BR112013029498A2 (pt)	2016-08-09
US20180368374A1 (en)	2018-12-27
EP2709445A1 (en)	2014-03-26
CN105112450A (zh)	2015-12-02
KR20200063264A (ko)	2020-06-04
US20140096275A1 (en)	2014-04-03
KR20140034229A (ko)	2014-03-19
PH12020500244A1 (en)	2024-06-24
CN103687482A (zh)	2014-03-26
US9820475B2 (en)	2017-11-21
DK2709445T3 (en)	2018-11-19
KR20230132606A (ko)	2023-09-15
KR102807016B1 (ko)	2025-05-14
EP3420813A1 (en)	2019-01-02
US11019809B2 (en)	2021-06-01
MX2013013427A (es)	2014-09-04
MX357421B (es)	2018-07-09
US10405526B2 (en)	2019-09-10
JP2019193660A (ja)	2019-11-07
CA3184311A1 (en)	2012-11-22
KR20240014587A (ko)	2024-02-01
ES2691618T3 (es)	2018-11-28
AU2018256670B2 (en)	2020-09-24
CA2836288A1 (en)	2012-11-22
US10080353B2 (en)	2018-09-25
RU2644673C2 (ru)	2018-02-13
JP6970525B2 (ja)	2021-11-24
JP2026065056A (ja)	2026-04-14
KR102428306B1 (ko)	2022-08-03
KR20220111739A (ko)	2022-08-09
CN111593025A (zh)	2020-08-28
AU2023219858A1 (en)	2023-09-28
PL2709445T3 (pl)	2019-01-31
CY1120890T1 (el)	2019-12-11
JP2017158579A (ja)	2017-09-14
AU2020294305A1 (en)	2021-02-11
KR102627319B1 (ko)	2024-01-23
WO2012158828A1 (en)	2012-11-22
PH12013502360A1 (en)	2014-01-06
US12527305B2 (en)	2026-01-20
JP2014519323A (ja)	2014-08-14
JP2024069309A (ja)	2024-05-21
MX383372B (es)	2025-03-13
AU2017202540B2 (en)	2018-08-09
US20200137992A1 (en)	2020-05-07
AU2018256670A1 (en)	2018-12-06
EP2709445A4 (en)	2015-03-25
JP2022081637A (ja)	2022-05-31
AU2017202540A1 (en)	2017-05-18

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