PL2709445T3 - Zwierzęta odporne na wirus zespołu rozrodczo-oddechowego świń - Google Patents

Zwierzęta odporne na wirus zespołu rozrodczo-oddechowego świń

Info

Publication number: PL2709445T3
Authority: PL; Poland
Prior art keywords: respiratory syndrome; syndrome virus; porcine reproductive; virus resistant; resistant animals
Prior art date: 2011-05-16

Application number

PL12785983T

Other languages

English (en)

Inventor

Randall S. Prather

Kevin D. Wells

Kristin M. Whitworth

Original Assignee

The Curators Of The University Of Missouri

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2011-05-16

Filing date

2012-05-16

Publication date

2019-01-31

2012-05-16 Application filed by The Curators Of The University Of Missouri filed Critical The Curators Of The University Of Missouri

2019-01-31 Publication of PL2709445T3 publication Critical patent/PL2709445T3/pl

Links

241001465754 Metazoa Species 0.000 title 1
241001135989 Porcine reproductive and respiratory syndrome virus Species 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A01K67/0275—Genetically modified vertebrates, e.g. transgenic
- A01K67/0276—Knock-out vertebrates
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A01K67/0275—Genetically modified vertebrates, e.g. transgenic
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/07—Animals genetically altered by homologous recombination
- A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/15—Animals comprising multiple alterations of the genome, by transgenesis or homologous recombination, e.g. obtained by cross-breeding
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/108—Swine
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/02—Animal zootechnically ameliorated
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/7056—Lectin superfamily, e.g. CD23, CD72
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70596—Molecules with a "CD"-designation not provided for elsewhere
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/80—Vectors containing sites for inducing double-stranded breaks, e.g. meganuclease restriction sites

Landscapes

Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Genetics & Genomics (AREA)
Zoology (AREA)
Biotechnology (AREA)
Environmental Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Biomedical Technology (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical & Material Sciences (AREA)
Wood Science & Technology (AREA)
General Engineering & Computer Science (AREA)
Animal Husbandry (AREA)
Animal Behavior & Ethology (AREA)
Biodiversity & Conservation Biology (AREA)
Microbiology (AREA)
Biochemistry (AREA)
Plant Pathology (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Physics & Mathematics (AREA)
Cell Biology (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

PL12785983T 2011-05-16 2012-05-16 Zwierzęta odporne na wirus zespołu rozrodczo-oddechowego świń PL2709445T3 (pl)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US201161519076P	2011-05-16	2011-05-16
PCT/US2012/038193 WO2012158828A1 (en)	2011-05-16	2012-05-16	Porcine reproductive and respiratory syndrome virus resistant animals
EP12785983.3A EP2709445B1 (en)	2011-05-16	2012-05-16	Porcine reproductive and respiratory syndrome virus resistant animals

Publications (1)

Publication Number	Publication Date
PL2709445T3 true PL2709445T3 (pl)	2019-01-31

Family

ID=47177326

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL12785983T PL2709445T3 (pl)	2011-05-16	2012-05-16	Zwierzęta odporne na wirus zespołu rozrodczo-oddechowego świń

Country Status (22)

Country	Link
US (6)	US9820475B2 (pl)
EP (2)	EP3420813A1 (pl)
JP (6)	JP2014519323A (pl)
KR (6)	KR102574897B1 (pl)
CN (3)	CN111593025A (pl)
AU (5)	AU2012255744A1 (pl)
BR (1)	BR112013029498A8 (pl)
CA (2)	CA2836288A1 (pl)
CY (1)	CY1120890T1 (pl)
DK (1)	DK2709445T3 (pl)
ES (1)	ES2691618T3 (pl)
HK (1)	HK1215282A1 (pl)
HR (1)	HRP20181729T1 (pl)
HU (1)	HUE039793T2 (pl)
LT (1)	LT2709445T (pl)
MX (2)	MX357421B (pl)
PH (2)	PH12020500244A1 (pl)
PL (1)	PL2709445T3 (pl)
PT (1)	PT2709445T (pl)
RU (1)	RU2644673C2 (pl)
SI (1)	SI2709445T1 (pl)
WO (1)	WO2012158828A1 (pl)

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PT2709445T (pt) *	2011-05-16	2018-11-27	Univ Missouri	Animais resistentes ao vírus da síntese reprodutiva e respiratória porcino
GB201313235D0 (en) *	2013-07-24	2013-09-04	Univ Edinburgh	Antiviral Compositions Methods and Animals
WO2015153647A1 (en) *	2014-03-31	2015-10-08	Mice With Horns, Llc	Method of preventing or reducing virus transmission in animals
CN104593422A (zh) *	2015-01-08	2015-05-06	中国农业大学	一种抗蓝耳病克隆猪的制备方法
JP6929527B2 (ja) *	2015-03-04	2021-09-01	株式会社ポル・メド・テック	安定した表現型を示す疾患モデルブタおよびその作製方法
CA3255239A1 (en) *	2015-08-06	2026-03-02	The Curators Of The University Of Missouri	Pathogen-resistant animals having modified cd163 genes
RS65691B1 (sr) *	2015-08-06	2024-07-31	Univ Missouri	Svinja i ćelije rezistentne na virus reproduktivnog i respiratornog sindroma svinja (prrsv) koje imaju modifikovane cd163 gene
GB201617559D0 (en)	2016-10-17	2016-11-30	University Court Of The University Of Edinburgh The	Swine comprising modified cd163 and associated methods
WO2019079285A1 (en)	2017-10-16	2019-04-25	Kansas State University Research Foundation	METHODS AND COMPOSITIONS FOR TREATMENT AND PROTECTION AGAINST DYSGENESIC AND RESPIRATORY PORK SYNDROME VIRUS
CN107937345B (zh) *	2017-11-16	2019-01-29	山东蓝思种业股份有限公司	一种制备同时敲除cd163基因和cd13基因的猪成纤维细胞的方法
KR102680060B1 (ko) *	2018-04-17	2024-07-02	더 큐레이터스 오브 더 유니버시티 오브 미주리	바이러스에 의한 감염으로부터 돼지 태아를 보호하는 방법
US11160260B2 (en)	2018-04-17	2021-11-02	The Curators Of The University Of Missouri	Methods for protecting porcine fetuses from infection with porcine reproductive and respiratory syndrome virus (PRRSV)
MX2020010926A (es) *	2018-04-27	2021-01-08	Univ Missouri	Animales resistentes a patogenos que tienen genes aminopeptidasa n (anpep) modificados.
CN109197780A (zh) *	2018-11-26	2019-01-15	湖北天牧畜禽有限公司	一种减少仔猪生病的养殖方法
WO2021024123A1 (en) *	2019-08-06	2021-02-11	Nzeno Limited	Donor pigs for xenotransplantation
CA3179710A1 (en) *	2020-05-05	2021-11-11	Andrew Mark CIGAN	Methods for improving the health of porcine species by targeted inactivation of cd163
ES3064029T3 (en) *	2021-01-05	2026-04-22	Public Univ Corp Yokohama City Univ	Biomarker for determining fertility, and determining method using same

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US5683993A (en)	1995-06-22	1997-11-04	Ciba Vision Corporation	Compositions and methods for stabilizing polymers
AU715468B2 (en)	1995-06-22	2000-02-03	Minnesota Mining And Manufacturing Company	Stable hydroalcoholic compositions
GB9517779D0 (en)	1995-08-31	1995-11-01	Roslin Inst Edinburgh	Biological manipulation
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RS65691B1 (sr)	2015-08-06	2024-07-31	Univ Missouri	Svinja i ćelije rezistentne na virus reproduktivnog i respiratornog sindroma svinja (prrsv) koje imaju modifikovane cd163 gene

2012
- 2012-05-16 PT PT12785983T patent/PT2709445T/pt unknown
- 2012-05-16 MX MX2013013427A patent/MX357421B/es active IP Right Grant
- 2012-05-16 PH PH1/2020/500244A patent/PH12020500244A1/en unknown
- 2012-05-16 CN CN202010588447.0A patent/CN111593025A/zh active Pending
- 2012-05-16 US US14/117,943 patent/US9820475B2/en active Active
- 2012-05-16 PL PL12785983T patent/PL2709445T3/pl unknown
- 2012-05-16 HU HUE12785983A patent/HUE039793T2/hu unknown
- 2012-05-16 WO PCT/US2012/038193 patent/WO2012158828A1/en not_active Ceased
- 2012-05-16 CA CA2836288A patent/CA2836288A1/en active Pending
- 2012-05-16 KR KR1020227026347A patent/KR102574897B1/ko active Active
- 2012-05-16 CN CN201280023487.4A patent/CN103687482A/zh active Pending
- 2012-05-16 CN CN201510463471.0A patent/CN105112450A/zh active Pending
- 2012-05-16 MX MX2018008377A patent/MX383372B/es unknown
- 2012-05-16 CA CA3184311A patent/CA3184311A1/en active Pending
- 2012-05-16 JP JP2014511498A patent/JP2014519323A/ja active Pending
- 2012-05-16 KR KR1020237029748A patent/KR102627319B1/ko active Active
- 2012-05-16 RU RU2013155677A patent/RU2644673C2/ru active
- 2012-05-16 AU AU2012255744A patent/AU2012255744A1/en not_active Abandoned
- 2012-05-16 LT LTEP12785983.3T patent/LT2709445T/lt unknown
- 2012-05-16 EP EP18189039.3A patent/EP3420813A1/en active Pending
- 2012-05-16 DK DK12785983.3T patent/DK2709445T3/en active
- 2012-05-16 SI SI201231423T patent/SI2709445T1/sl unknown
- 2012-05-16 PH PH1/2013/502360A patent/PH12013502360A1/en unknown
- 2012-05-16 KR KR1020257015124A patent/KR20250073511A/ko active Pending
- 2012-05-16 KR KR1020207015089A patent/KR102428306B1/ko active Active
- 2012-05-16 HR HRP20181729TT patent/HRP20181729T1/hr unknown
- 2012-05-16 EP EP12785983.3A patent/EP2709445B1/en active Active
- 2012-05-16 ES ES12785983.3T patent/ES2691618T3/es active Active
- 2012-05-16 KR KR1020247001725A patent/KR102807016B1/ko active Active
- 2012-05-16 KR KR1020137033359A patent/KR20140034229A/ko not_active Ceased
- 2012-05-16 BR BR112013029498A patent/BR112013029498A8/pt not_active Application Discontinuation
2016
- 2016-03-21 HK HK16103259.2A patent/HK1215282A1/zh unknown
2017
- 2017-04-19 AU AU2017202540A patent/AU2017202540B2/en active Active
- 2017-05-09 JP JP2017092768A patent/JP6970525B2/ja active Active
- 2017-10-13 US US15/783,417 patent/US10080353B2/en active Active
2018
- 2018-08-24 US US16/111,631 patent/US10405526B2/en active Active
- 2018-11-02 AU AU2018256670A patent/AU2018256670B2/en active Active
- 2018-11-07 CY CY181101169T patent/CY1120890T1/el unknown
2019
- 2019-07-04 JP JP2019125475A patent/JP2019193660A/ja not_active Withdrawn
- 2019-08-30 US US16/556,878 patent/US11019809B2/en active Active
2020
- 2020-12-24 AU AU2020294305A patent/AU2020294305A1/en not_active Abandoned
2021
- 2021-04-28 US US17/242,963 patent/US12527305B2/en active Active
2022
- 2022-03-16 JP JP2022041628A patent/JP2022081637A/ja not_active Withdrawn
2023
- 2023-08-22 AU AU2023219858A patent/AU2023219858A1/en not_active Abandoned
2024
- 2024-03-06 JP JP2024033472A patent/JP2024069309A/ja active Pending
- 2024-04-19 US US18/640,282 patent/US20240284884A1/en active Pending
2026
- 2026-01-08 JP JP2026001964A patent/JP2026065056A/ja active Pending

Also Published As

Publication number	Publication date
WO2012158828A1 (en)	2012-11-22
US12527305B2 (en)	2026-01-20
AU2018256670A1 (en)	2018-12-06
HUE039793T2 (hu)	2019-02-28
CN105112450A (zh)	2015-12-02
MX2013013427A (es)	2014-09-04
AU2018256670B2 (en)	2020-09-24
JP2024069309A (ja)	2024-05-21
JP2017158579A (ja)	2017-09-14
DK2709445T3 (en)	2018-11-19
AU2012255744A1 (en)	2014-01-09
AU2023219858A1 (en)	2023-09-28
KR20230132606A (ko)	2023-09-15
CA2836288A1 (en)	2012-11-22
BR112013029498A2 (pt)	2016-08-09
KR20240014587A (ko)	2024-02-01
MX357421B (es)	2018-07-09
BR112013029498A8 (pt)	2017-02-21
KR20200063264A (ko)	2020-06-04
AU2017202540A1 (en)	2017-05-18
MX383372B (es)	2025-03-13
US20240284884A1 (en)	2024-08-29
KR102428306B1 (ko)	2022-08-03
KR102627319B1 (ko)	2024-01-23
HK1215282A1 (zh)	2016-08-19
EP2709445A4 (en)	2015-03-25
US20140096275A1 (en)	2014-04-03
KR102574897B1 (ko)	2023-09-06
US20180368374A1 (en)	2018-12-27
AU2017202540B2 (en)	2018-08-09
CN111593025A (zh)	2020-08-28
RU2013155677A (ru)	2015-06-27
SI2709445T1 (sl)	2018-11-30
CA3184311A1 (en)	2012-11-22
HRP20181729T1 (hr)	2018-12-28
RU2644673C2 (ru)	2018-02-13
EP3420813A1 (en)	2019-01-02
KR20140034229A (ko)	2014-03-19
PH12020500244A1 (en)	2024-06-24
ES2691618T3 (es)	2018-11-28
LT2709445T (lt)	2018-11-12
JP2026065056A (ja)	2026-04-14
EP2709445B1 (en)	2018-10-03
US9820475B2 (en)	2017-11-21
PT2709445T (pt)	2018-11-27
JP6970525B2 (ja)	2021-11-24
JP2014519323A (ja)	2014-08-14
US11019809B2 (en)	2021-06-01
KR102807016B1 (ko)	2025-05-14
US10405526B2 (en)	2019-09-10
PH12013502360A1 (en)	2014-01-06
US20200137992A1 (en)	2020-05-07
KR20250073511A (ko)	2025-05-27
US20180027783A1 (en)	2018-02-01
JP2022081637A (ja)	2022-05-31
JP2019193660A (ja)	2019-11-07
EP2709445A1 (en)	2014-03-26
CN103687482A (zh)	2014-03-26
AU2020294305A1 (en)	2021-02-11
CY1120890T1 (el)	2019-12-11
US20210259219A1 (en)	2021-08-26
KR20220111739A (ko)	2022-08-09
US10080353B2 (en)	2018-09-25

Publication	Publication Date	Title
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