LT2890699T - Kristalinės 1-(5'-(5-(3,5-dichlor-4-fluorfenil)-5-(trifluormetil)-4,5-dihidroizoksazol-3-il)-3'h-spiro[azetidin-3,1'-izobenzofuran]-1-il)-2-(metilsulfonil)etano formos - Google Patents

Kristalinės 1-(5'-(5-(3,5-dichlor-4-fluorfenil)-5-(trifluormetil)-4,5-dihidroizoksazol-3-il)-3'h-spiro[azetidin-3,1'-izobenzofuran]-1-il)-2-(metilsulfonil)etano formos

Info

Publication number: LT2890699T
Authority: LT; Lithuania
Prior art keywords: dihydroisoxazol; isobenzofuran; azetidine; ethanone; methylsulfonyl
Prior art date: 2012-08-31

Application number

LTEP13756985.1T

Other languages

English (en)

Inventor

Denis Billen

Matthew Joseph Birchmeier

Ronald J. VANDERROEST

Original Assignee

Zoetis Services Llc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2012-08-31

Filing date

2013-08-28

Publication date

2018-06-25

2013-08-28 Application filed by Zoetis Services Llc filed Critical Zoetis Services Llc

2018-06-25 Publication of LT2890699T publication Critical patent/LT2890699T/lt

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- C07D491/107—Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/14—Ectoparasiticides, e.g. scabicides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Tropical Medicine & Parasitology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

LTEP13756985.1T 2012-08-31 2013-08-28 Kristalinės 1-(5'-(5-(3,5-dichlor-4-fluorfenil)-5-(trifluormetil)-4,5-dihidroizoksazol-3-il)-3'h-spiro[azetidin-3,1'-izobenzofuran]-1-il)-2-(metilsulfonil)etano formos LT2890699T (lt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US201261695410P	2012-08-31	2012-08-31
PCT/US2013/056945 WO2014036056A1 (en)	2012-08-31	2013-08-28	Crystalline forms of 1-(5'-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-3'h-spiro[azetidine-3,1'-isobenzofuran]-1-yl)-2-(methylsulfonyl)ethanone

Publications (1)

Publication Number	Publication Date
LT2890699T true LT2890699T (lt)	2018-06-25

Family

ID=49115603

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
LTEP13756985.1T LT2890699T (lt)	2012-08-31	2013-08-28	Kristalinės 1-(5'-(5-(3,5-dichlor-4-fluorfenil)-5-(trifluormetil)-4,5-dihidroizoksazol-3-il)-3'h-spiro[azetidin-3,1'-izobenzofuran]-1-il)-2-(metilsulfonil)etano formos

Country Status (28)

Country	Link
US (1)	US9200003B2 (lt)
EP (1)	EP2890699B1 (lt)
JP (1)	JP6109942B2 (lt)
KR (1)	KR101736643B1 (lt)
CN (1)	CN104812758B (lt)
AR (1)	AR092409A1 (lt)
AU (1)	AU2013308887B2 (lt)
BR (1)	BR112015004135B8 (lt)
CA (1)	CA2881467C (lt)
CL (1)	CL2015000332A1 (lt)
CY (1)	CY1120611T1 (lt)
DK (1)	DK2890699T3 (lt)
ES (1)	ES2671271T3 (lt)
HR (1)	HRP20180861T1 (lt)
HU (1)	HUE037667T2 (lt)
LT (1)	LT2890699T (lt)
MX (1)	MX351463B (lt)
NO (1)	NO2931268T3 (lt)
NZ (1)	NZ704175A (lt)
PH (1)	PH12015500441A1 (lt)
PL (1)	PL2890699T3 (lt)
PT (1)	PT2890699T (lt)
RS (1)	RS57284B1 (lt)
RU (1)	RU2614978C2 (lt)
SI (1)	SI2890699T1 (lt)
TR (1)	TR201807735T4 (lt)
WO (1)	WO2014036056A1 (lt)
ZA (1)	ZA201500728B (lt)

Families Citing this family (70)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BR112015004826A2 (pt) *	2012-09-07	2017-07-04	Zoetis Llc	derivados espirocíclicos como agentes antiparasíticos
ES2748631T3 (es)	2012-09-07	2020-03-17	Zoetis Services Llc	Combinaciones parasiticidas de isoxazolina espirocíclica
WO2014189837A1 (en) *	2013-05-20	2014-11-27	Zoetis Llc	Long-acting spiro-isoxazoline antiparasitic compositions
WO2016022066A1 (en)	2014-08-04	2016-02-11	Jerry Tan Eye Surgery Pte Ltd	Pharmaceutical compositions for demodex related blepharitis and eyelid crusting
BR112017005140A2 (pt)	2014-10-06	2018-01-23	Basf Se	compostos, mistura, composição, métodos para a proteção de culturas e para o combate ou controle de praga de invertebrados, método não terapêutico para o tratamento de animais infestados ou infectados por parasitas e semente
WO2016071499A1 (en)	2014-11-06	2016-05-12	Basf Se	3-pyridyl heterobicyclic compound for controlling invertebrate pests
BR112017021450B1 (pt)	2015-04-07	2021-12-28	Basf Agrochemical Products B.V.	Métodos de controle de pragas, método de melhoria da saúde vegetal e semente revestida
WO2016198613A1 (en)	2015-06-11	2016-12-15	Basf Se	N-(thio)acylimino compounds
WO2016198611A1 (en)	2015-06-11	2016-12-15	Basf Se	N-(thio)acylimino heterocyclic compounds
WO2017016883A1 (en)	2015-07-24	2017-02-02	Basf Se	Process for preparation of cyclopentene compounds
CR20180254A (es)	2015-10-02	2018-08-13	Basf Se	Compuestos de imino con un sustituyente de 2-cloropirimidin-5-ilo como agentes de control de plagas
PL3383183T3 (pl)	2015-11-30	2020-11-16	Basf Se	Kompozycje zawierające cis-jasmon i bacillus amyloliquefaciens
EP3426660A1 (en)	2016-03-09	2019-01-16	Basf Se	Spirocyclic derivatives
BR112018068042A2 (pt)	2016-03-11	2019-01-08	Basf Se	métodos para controlar pragas de plantas, material de propagação de planta e uso de um ou mais compostos de fórmula i
AU2017242539B2 (en)	2016-04-01	2020-10-15	Basf Se	Bicyclic compounds
WO2018082962A1 (en) *	2016-11-02	2018-05-11	Basf Se	Process for preparation of tetrahydrothiophene derivatives
EP3555050A1 (en)	2016-12-16	2019-10-23	Basf Se	Pesticidal compounds
WO2018162312A1 (en)	2017-03-10	2018-09-13	Basf Se	Spirocyclic derivatives
WO2018166855A1 (en)	2017-03-16	2018-09-20	Basf Se	Heterobicyclic substituted dihydroisoxazoles
WO2018177781A1 (en)	2017-03-28	2018-10-04	Basf Se	Pesticidal compounds
CN116076518A (zh)	2017-03-31	2023-05-09	巴斯夫欧洲公司	用于防除动物害虫的嘧啶鎓化合物及其混合物
WO2018192793A1 (en)	2017-04-20	2018-10-25	Basf Se	Substituted rhodanine derivatives
AU2018260098A1 (en)	2017-04-26	2019-10-31	Basf Se	Substituted succinimide derivatives as pesticides
KR102694625B1 (ko)	2017-05-10	2024-08-12	바스프 에스이	바이시클릭 화합물
WO2018224455A1 (en)	2017-06-07	2018-12-13	Basf Se	Substituted cyclopropyl derivatives
US20210179620A1 (en)	2017-06-16	2021-06-17	Basf Se	Mesoionic imidazolium compounds and derivatives for combating animal pests
US11542280B2 (en)	2017-06-19	2023-01-03	Basf Se	Substituted pyrimidinium compounds and derivatives for combating animal pests
WO2018234488A1 (en)	2017-06-23	2018-12-27	Basf Se	Substituted cyclopropyl derivatives
WO2019042932A1 (en)	2017-08-31	2019-03-07	Basf Se	METHOD FOR CONTROLLING RICE PARASITES IN RICE
EP3453706A1 (en)	2017-09-08	2019-03-13	Basf Se	Pesticidal imidazole compounds
US11399543B2 (en)	2017-10-13	2022-08-02	Basf Se	Substituted 1,2,3,5-tetrahydroimidazo[1,2-a]pyrimidiniumolates for combating animal pests
JP2021503465A (ja) *	2017-11-16	2021-02-12	アビスタファーマソリューションズ，インコーポレーテッド	単一エナンチオマーの抗寄生生物化合物
AU2018385766B2 (en)	2017-12-15	2022-12-01	Tarsus Pharmaceuticals, Inc.	Isoxazoline parasiticide formulations and methods for treating blepharitis
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US11414438B2 (en)	2018-01-09	2022-08-16	Basf Se	Silylethynyl hetaryl compounds as nitrification inhibitors
WO2019137995A1 (en)	2018-01-11	2019-07-18	Basf Se	Novel pyridazine compounds for controlling invertebrate pests
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IL276745B2 (en)	2018-02-28	2023-10-01	Basf Se	Use of N-functional alkoxy pyrazole compounds as nitrification inhibitors
CA3089374A1 (en)	2018-02-28	2019-09-06	Basf Se	Use of alkoxypyrazoles as nitrification inhibitors
WO2019175713A1 (en)	2018-03-14	2019-09-19	Basf Corporation	New catechol molecules and their use as inhibitors to p450 related metabolic pathways
WO2019175712A1 (en)	2018-03-14	2019-09-19	Basf Corporation	New uses for catechol molecules as inhibitors to glutathione s-transferase metabolic pathways
WO2019185413A1 (en)	2018-03-27	2019-10-03	Basf Se	Pesticidal substituted cyclopropyl derivatives
WO2019219529A1 (en)	2018-05-15	2019-11-21	Basf Se	Mixtures comprising benzpyrimoxan and oxazosulfyl and uses and methods of applying them
WO2019224092A1 (en)	2018-05-22	2019-11-28	Basf Se	Pesticidally active c15-derivatives of ginkgolides
WO2020002472A1 (en)	2018-06-28	2020-01-02	Basf Se	Use of alkynylthiophenes as nitrification inhibitors
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AU2019348280A1 (en)	2018-09-28	2021-04-22	Basf Se	Method of controlling pests by seed treatment application of a mesoionic compound or mixture thereof
EP3643705A1 (en)	2018-10-24	2020-04-29	Basf Se	Pesticidal compounds
US12459934B2 (en)	2018-11-28	2025-11-04	Basf Se	Pesticidal compounds
BR112021009395A2 (pt)	2018-12-18	2021-08-10	Basf Se	compostos de pirimidínio substituídos, compostos de fórmula (i), métodos para proteger culturas, para o combate, controle, prevenção ou proteção, método não terapêutico para o tratamento de animais, semente e usos dos compostos de fórmula (i)
EP3696177A1 (en)	2019-02-12	2020-08-19	Basf Se	Heterocyclic compounds for the control of invertebrate pests
US12502377B2 (en)	2019-04-04	2025-12-23	Tarsus Pharmaceuticals, Inc.	Method of eradicating ticks that attach to humans using lotilaner formulations
EP3769623A1 (en)	2019-07-22	2021-01-27	Basf Se	Mesoionic imidazolium compounds and derivatives for combating animal pests
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EP3766879A1 (en)	2019-07-19	2021-01-20	Basf Se	Pesticidal pyrazole derivatives
WO2022061914A1 (zh) *	2020-09-28	2022-03-31	台州臻挚生物科技有限公司	一种3,5-二卤三氟苯乙酮及其衍生物的制备方法
EP4288398A1 (en)	2021-02-02	2023-12-13	Basf Se	Synergistic action of dcd and alkoxypyrazoles as nitrification inhibitors
EP4341248A1 (en)	2021-05-21	2024-03-27	Basf Se	Use of an n-functionalized alkoxy pyrazole compound as nitrification inhibitor
CA3219022A1 (en)	2021-05-21	2022-11-24	Barbara Nave	Use of ethynylpyridine compounds as nitrification inhibitors
BR112023027004A2 (pt)	2021-06-21	2024-03-12	Basf Se	Estrutura de metal-orgânica, uso da estrutura de metal-orgânica, composição para uso na redução da nitrificação, mistura agroquímica e métodos de redução da nitrificação, de tratamento de fertilizante ou composição de fertilizante e de preparação de uma estrutura de metal-orgânica
EP4358847A4 (en)	2021-06-23	2025-05-21	Kimtron, Inc.	System and method for ultra-close irradiation of rotating biomass
WO2023203066A1 (en)	2022-04-21	2023-10-26	Basf Se	Synergistic action as nitrification inhibitors of dcd oligomers with alkoxypyrazole and its oligomers
CA3263381A1 (en)	2022-08-02	2024-02-08	Basf Se	PYRAZOLO PESTICIDE COMPOUNDS
CN117263825A (zh) *	2023-11-23	2023-12-22	内蒙古百灵科技有限公司	一种双甲脒结晶的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20110288089A1 (en) *	2009-01-22	2011-11-24	Syngenta Crop Protection Llc	Insecticidal compounds
AU2011220041A1 (en)	2010-02-25	2012-08-23	Syngenta Limited	Process for the preparation of isoxazoline derivatives
ES2682303T3 (es) *	2010-08-05	2018-09-19	Zoetis Services Llc	Derivados de isoxazolina como agentes antiparasitarios
WO2012086462A1 (ja) *	2010-12-20	2012-06-28	日本曹達株式会社	イソオキサゾリン化合物および有害生物防除剤
PH12013501831B1 (en) *	2011-03-10	2019-06-14	Zoetis Services Llc	Spirocyclic isoxazoline derivatives as antiparasitic agents

2013
- 2013-08-28 BR BR112015004135A patent/BR112015004135B8/pt active IP Right Grant
- 2013-08-28 ES ES13756985.1T patent/ES2671271T3/es active Active
- 2013-08-28 CA CA2881467A patent/CA2881467C/en active Active
- 2013-08-28 SI SI201331062T patent/SI2890699T1/en unknown
- 2013-08-28 KR KR1020157004953A patent/KR101736643B1/ko active Active
- 2013-08-28 CN CN201380044821.9A patent/CN104812758B/zh active Active
- 2013-08-28 EP EP13756985.1A patent/EP2890699B1/en active Active
- 2013-08-28 HU HUE13756985A patent/HUE037667T2/hu unknown
- 2013-08-28 RS RS20180636A patent/RS57284B1/sr unknown
- 2013-08-28 JP JP2015529970A patent/JP6109942B2/ja active Active
- 2013-08-28 RU RU2015107052A patent/RU2614978C2/ru active
- 2013-08-28 MX MX2015002679A patent/MX351463B/es active IP Right Grant
- 2013-08-28 WO PCT/US2013/056945 patent/WO2014036056A1/en not_active Ceased
- 2013-08-28 TR TR2018/07735T patent/TR201807735T4/tr unknown
- 2013-08-28 PT PT137569851T patent/PT2890699T/pt unknown
- 2013-08-28 AU AU2013308887A patent/AU2013308887B2/en active Active
- 2013-08-28 LT LTEP13756985.1T patent/LT2890699T/lt unknown
- 2013-08-28 DK DK13756985.1T patent/DK2890699T3/en active
- 2013-08-28 PL PL13756985T patent/PL2890699T3/pl unknown
- 2013-08-28 HR HRP20180861TT patent/HRP20180861T1/hr unknown
- 2013-08-28 NZ NZ704175A patent/NZ704175A/en unknown
- 2013-08-28 US US14/422,098 patent/US9200003B2/en active Active
- 2013-08-30 AR ARP130103110A patent/AR092409A1/es unknown
- 2013-12-13 NO NO13863231A patent/NO2931268T3/no unknown
2015
- 2015-01-30 ZA ZA2015/00728A patent/ZA201500728B/en unknown
- 2015-02-11 CL CL2015000332A patent/CL2015000332A1/es unknown
- 2015-02-27 PH PH12015500441A patent/PH12015500441A1/en unknown
2018
- 2018-06-13 CY CY181100619T patent/CY1120611T1/el unknown

Also Published As

Publication number	Publication date
TR201807735T4 (tr)	2018-06-21
SI2890699T1 (en)	2018-07-31
EP2890699B1 (en)	2018-04-11
CY1120611T1 (el)	2019-12-11
EP2890699A1 (en)	2015-07-08
CA2881467A1 (en)	2014-03-06
AR092409A1 (es)	2015-04-22
KR101736643B1 (ko)	2017-05-16
CN104812758B (zh)	2017-05-03
BR112015004135B8 (pt)	2022-11-22
JP2015526522A (ja)	2015-09-10
HUE037667T2 (hu)	2018-09-28
AU2013308887B2 (en)	2015-11-12
HK1209125A1 (en)	2016-03-24
PH12015500441B1 (en)	2015-04-20
CA2881467C (en)	2017-08-29
BR112015004135B1 (pt)	2020-12-08
KR20150038366A (ko)	2015-04-08
CL2015000332A1 (es)	2015-05-15
DK2890699T3 (en)	2018-06-14
ES2671271T3 (es)	2018-06-05
CN104812758A (zh)	2015-07-29
HRP20180861T1 (hr)	2018-07-13
RU2614978C2 (ru)	2017-03-31
MX2015002679A (es)	2015-05-12
US9200003B2 (en)	2015-12-01
RU2015107052A (ru)	2016-10-20
JP6109942B2 (ja)	2017-04-05
AU2013308887A1 (en)	2015-02-19
NZ704175A (en)	2015-10-30
PT2890699T (pt)	2018-06-01
PL2890699T3 (pl)	2018-10-31
US20150183795A1 (en)	2015-07-02
RS57284B1 (sr)	2018-08-31
NO2931268T3 (lt)	2018-04-21
WO2014036056A1 (en)	2014-03-06
PH12015500441A1 (en)	2015-04-20
ZA201500728B (en)	2016-08-31
MX351463B (es)	2017-10-16
BR112015004135A2 (pt)	2017-07-04

Publication	Publication Date	Title
LT2890699T (lt)	2018-06-25	Kristalinės 1-(5'-(5-(3,5-dichlor-4-fluorfenil)-5-(trifluormetil)-4,5-dihidroizoksazol-3-il)-3'h-spiro[azetidin-3,1'-izobenzofuran]-1-il)-2-(metilsulfonil)etano formos
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SI2321235T1 (sl)	2019-11-29	Uporaba sestavka za pospeševanje strjevanja, ki vsebuje mehčalec
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WO2013186792A3 (en)	2014-02-06	Process for preparation of azilsartan medoxomil and its salts
ZA201700110B (en)	2018-04-25	Compounds comprising 1,1',2,5'-tetrahydrospiro[indole-3,2'-pyrrole]-2,5'-dione system as inhibitors p53-mdm2 protein-protein interaction
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IL233421A (en)	2016-04-21	Derivatives of the fungicide 3 - [(pyridine-2-ylmethoxyamino) (phenyl) methyl] -2-Converted 4,2,1 -Oxadiazole-5 (2h) - On
IL228270A0 (en)	2013-11-25	History of 1-h- pyrrolidine -4,2-dione spirocyclics converted in cis-alkoxy
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UA69857U (en)	2012-05-10	3-{2-[5-(3,5-diaryl)-4,5-dihydropyrazole-1-yl]-4-oxo-4h-thiazol-5-ylidene}-1,3-dihydroindole-2-ones exhibiting anticancer activity
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CO6930371A2 (es)	2014-04-28	Derivados fungicidas de 3-{fenil[(heterociclilmetoxi)imino]metil}-1,2,4-oxadiazol-5(4h)-ona sustituidos en 4
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