LT3116891T - Imunoglobulino gryninimas, naudojant išankstinio valymo pakopas - Google Patents

Imunoglobulino gryninimas, naudojant išankstinio valymo pakopas

Info

Publication number
LT3116891T
LT3116891T LTEP15708522.6T LT15708522T LT3116891T LT 3116891 T LT3116891 T LT 3116891T LT 15708522 T LT15708522 T LT 15708522T LT 3116891 T LT3116891 T LT 3116891T
Authority
LT
Lithuania
Prior art keywords
cleaning steps
immunoglobulin purification
immunoglobulin
purification
cleaning
Prior art date
Application number
LTEP15708522.6T
Other languages
English (en)
Inventor
Ferenc FELFÖLDI
Zsuzsa BENKÖ
Melinda Gaspar
Original Assignee
Richter Gedeon Nyrt.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from HU1400131A external-priority patent/HUP1400131A1/hu
Priority claimed from HU1500053A external-priority patent/HUP1500053A1/hu
Application filed by Richter Gedeon Nyrt. filed Critical Richter Gedeon Nyrt.
Publication of LT3116891T publication Critical patent/LT3116891T/lt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J39/00—Cation exchange; Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
    • B01J39/26—Cation exchangers for chromatographic processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J41/00—Anion exchange; Use of material as anion exchangers; Treatment of material for improving the anion exchange properties
    • B01J41/20—Anion exchangers for chromatographic processes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/165—Extraction; Separation; Purification by chromatography mixed-mode chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241—Tumor Necrosis Factors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2887—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Water Supply & Treatment (AREA)
  • Peptides Or Proteins (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
LTEP15708522.6T 2014-03-10 2015-03-09 Imunoglobulino gryninimas, naudojant išankstinio valymo pakopas LT3116891T (lt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
HU1400131A HUP1400131A1 (hu) 2014-03-10 2014-03-10 Immunoglobulin tisztítása elõtisztítási lépések alkalmazásával
HU1500053A HUP1500053A1 (hu) 2015-02-09 2015-02-09 Immunglobulin tisztítása elõtisztítási lépések alkalmazásával
PCT/EP2015/054862 WO2015135884A1 (en) 2014-03-10 2015-03-09 Immunoglobulin purification using pre-cleaning steps

Publications (1)

Publication Number Publication Date
LT3116891T true LT3116891T (lt) 2020-03-25

Family

ID=89991731

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEP15708522.6T LT3116891T (lt) 2014-03-10 2015-03-09 Imunoglobulino gryninimas, naudojant išankstinio valymo pakopas

Country Status (15)

Country Link
US (1) US10487138B2 (lt)
EP (2) EP3674310A1 (lt)
JP (1) JP6293907B2 (lt)
KR (1) KR101921552B1 (lt)
CN (1) CN106103465B (lt)
CA (1) CA2930350C (lt)
DK (1) DK3116891T3 (lt)
ES (1) ES2784749T3 (lt)
HR (1) HRP20200711T1 (lt)
HU (1) HUE048782T2 (lt)
LT (1) LT3116891T (lt)
PL (1) PL3116891T3 (lt)
PT (1) PT3116891T (lt)
SI (1) SI3116891T1 (lt)
WO (1) WO2015135884A1 (lt)

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ES2784749T3 (es) 2014-03-10 2020-09-30 Richter Gedeon Nyrt Purificación de inmunoglobulina con el uso de etapas de limpieza previa
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KR20190047376A (ko) 2017-10-27 2019-05-08 주식회사 녹십자 개선된 면역글로불린의 정제방법
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EP4118108A4 (en) * 2020-04-10 2024-05-15 Plasma Technologies, LLC COMPOSITIONS AND METHODS FOR HIGHLY EFFICIENT SIMPLIFIED PROTEIN ISOLATION
CN113563469A (zh) * 2020-04-28 2021-10-29 江苏中新医药有限公司 高回收率纯化阿达木单抗的方法
EP4142792A4 (en) 2020-05-01 2024-11-27 Kashiv Biosciences, LLC An improved process of purification of protein
EP4142905A4 (en) * 2020-05-01 2024-11-13 Kashiv Biosciences, LLC IMPROVED PROCESS FOR PURIFICATION OF PROTEIN
PL4263568T3 (pl) * 2020-12-18 2025-11-24 Richter Gedeon Nyrt. Sposoby oczyszczania poddanego ponownemu fałdowaniu białka fuzyjnego peptydu Fc
EP4392156A4 (en) * 2021-10-08 2025-06-25 Kashiv Biosciences, LLC Separation of pre-peak and post-peak in fusion protein sample by using size exclusion high performance liquid chromatography
WO2023057994A1 (en) * 2021-10-08 2023-04-13 Kashiv Biosciences, Llc Separation of pre-peak in fusion protein sample by using size exclusion high performance liquid chromatography
CN114133446A (zh) * 2021-12-31 2022-03-04 方坦思(上海)生物医药有限公司 单克隆抗体的纯化方法
CN115304673B (zh) * 2022-06-24 2024-10-01 上海赛伦生物技术股份有限公司 一种马抗破伤风特异性免疫球蛋白F(ab’)2的纯化方法及其应用

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Also Published As

Publication number Publication date
JP2017507907A (ja) 2017-03-23
CN106103465B (zh) 2021-01-08
EP3674310A1 (en) 2020-07-01
DK3116891T3 (da) 2020-05-04
HRP20200711T1 (hr) 2020-07-24
HUE048782T2 (hu) 2020-08-28
PT3116891T (pt) 2020-05-18
WO2015135884A1 (en) 2015-09-17
EP3116891B1 (en) 2020-02-12
PL3116891T3 (pl) 2020-07-27
SI3116891T1 (sl) 2020-07-31
KR101921552B1 (ko) 2018-11-23
CA2930350A1 (en) 2015-09-17
US10487138B2 (en) 2019-11-26
EP3116891A1 (en) 2017-01-18
KR20160124107A (ko) 2016-10-26
CA2930350C (en) 2021-04-06
US20170058019A1 (en) 2017-03-02
CN106103465A (zh) 2016-11-09
ES2784749T3 (es) 2020-09-30
JP6293907B2 (ja) 2018-03-14

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