LT3144389T - In vitro susintetintos viengrandės rnr gavimas ir panaudojimas įvedimui į žinduolio ląsteles, siekiant sužadinti biologinį arba biocheminį poveikį - Google Patents

In vitro susintetintos viengrandės rnr gavimas ir panaudojimas įvedimui į žinduolio ląsteles, siekiant sužadinti biologinį arba biocheminį poveikį

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Publication number
LT3144389T
LT3144389T LTEP16186283.4T LT16186283T LT3144389T LT 3144389 T LT3144389 T LT 3144389T LT 16186283 T LT16186283 T LT 16186283T LT 3144389 T LT3144389 T LT 3144389T
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LT
Lithuania
Prior art keywords
vitro
induce
biological
introducing
making
Prior art date
Application number
LTEP16186283.4T
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English (en)
Inventor
Judith Meis
Anthony D. PERSON
Cynthia S. Chin
Jerome Jendrisak
Gary A. Dahl
Original Assignee
Cellscript, Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cellscript, Llc filed Critical Cellscript, Llc
Publication of LT3144389T publication Critical patent/LT3144389T/lt

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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
    • A61K48/0066—Manipulation of the nucleic acid to modify its expression pattern, e.g. enhance its duration of expression, achieved by the presence of particular introns in the delivered nucleic acid
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/7105—Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
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    • A61K48/0008—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition
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    • A61K48/0041—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition wherein the non-active part clearly interacts with the delivered nucleic acid the non-active part being polymeric
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LTEP16186283.4T 2011-12-30 2012-12-31 In vitro susintetintos viengrandės rnr gavimas ir panaudojimas įvedimui į žinduolio ląsteles, siekiant sužadinti biologinį arba biocheminį poveikį LT3144389T (lt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161582080P 2011-12-30 2011-12-30
US201161582050P 2011-12-30 2011-12-30
US201261651738P 2012-05-25 2012-05-25

Publications (1)

Publication Number Publication Date
LT3144389T true LT3144389T (lt) 2018-08-10

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ID=47559751

Family Applications (2)

Application Number Title Priority Date Filing Date
LTEP18170777.9T LT3421601T (lt) 2011-12-30 2012-12-31 In vitro susintetintos ssrnr gamyba ir panaudojimas įvedimui į žinduolių ląsteles biologinio arba biocheminio poveikio sukėlimui
LTEP16186283.4T LT3144389T (lt) 2011-12-30 2012-12-31 In vitro susintetintos viengrandės rnr gavimas ir panaudojimas įvedimui į žinduolio ląsteles, siekiant sužadinti biologinį arba biocheminį poveikį

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LTEP18170777.9T LT3421601T (lt) 2011-12-30 2012-12-31 In vitro susintetintos ssrnr gamyba ir panaudojimas įvedimui į žinduolių ląsteles biologinio arba biocheminio poveikio sukėlimui

Country Status (12)

Country Link
US (4) US10201620B2 (lt)
EP (6) EP3144389B1 (lt)
AU (5) AU2012362113B2 (lt)
CA (1) CA2862377A1 (lt)
DK (3) DK3144389T3 (lt)
ES (2) ES2770314T3 (lt)
HR (1) HRP20200251T1 (lt)
HU (1) HUE047947T2 (lt)
LT (2) LT3421601T (lt)
PL (2) PL3144389T3 (lt)
SI (1) SI3421601T1 (lt)
WO (1) WO2013102203A1 (lt)

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TR201809547T4 (tr) 2012-11-09 2018-07-23 Biontech Rna Pharmaceuticals Gmbh Hücresel RNA ifadesine yönelik yöntem.
PL2922554T3 (pl) 2012-11-26 2022-06-20 Modernatx, Inc. Na zmodyfikowany na końcach
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